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Journal of Pharmacy Tiara Bunda
Published by Politeknik Tiara Bunda
ISSN : -     EISSN : 30323657     DOI : 10.62619
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Journal of Pharmacy Tiara Bunda (JPTB) is an academic journal related to the fields of pharmacy and healthcare, published by an institution named "Tiara Bunda." JPTB serves as a platform for academics, researchers, and professionals in the field of pharmacy to share knowledge, research findings, innovations, and the latest developments in the pharmaceutical industry. The journal aims to provide a venue for exploring various topics in the field of pharmacy, including but not limited to pharmacology, pharmaceutical chemistry, pharmacokinetics, pharmacodynamics, clinical pharmacy, pharmacogenomics, pharmaceutical sciences, drug development, and rational drug use.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 48 Documents
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The LIQUID SOAP FORMULATION OF AVOCADO (Persea americana) ETHANOL EXTRACT AGAINST Staphylococcus aureus BACTERIA: FORMULASI SABUN CAIR EKSTRAK ETANOL KULIT ALPUKAT (Persea americana) TERHADAP BAKTERI Sthapylococcus aureus Suryani, Ade Irma
Journal of Pharmacy Tiara Bunda Vol. 5 No. 1 (2025): Vol. 5 No. 1 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Avocado peels contain Flavanoid compounds and alkaloids as antibacterial. In this study, the ethanol extract of Avocado peels was formulated as a liquid soap using concentrations of FI (1%), FII (3%) and FIII (5%). The aim of this study was to formulate a liquid soap from a sample of Avocado peel extract against the antibacterial activity of Staphylococcus aureus using the agar diffusion method in wells. Physical evaluation of liquid soap preparations includes several parameters, namely organoleptic tests including odor, shape and color, pH test, foam stability test, viscosity test and homogeneity test. The results obtained from testing liquid soap using ethanol extract of Avocado peels with varying concentrations of 1%, 3% and 5% can inhibit the growth of Staphylococcus aureus bacteria, namely 1% = 19.6, 3% = 21.6 and 5% = 25.8. Based on the results of this study it can be concluded that the ethanol extract of Avocado peels (Persea americana) can be formulated in the form of liquid soap and is effective against inhibition of Staphylococcus aureus bacteria. And in this study FIII fulfilled the physical quality evaluation test and had activity as an antibacterial, with the resulting inhibition zone at a concentration of 5% = 26.6 mm, very strong category.
REVIEW ARTIKEL : POTENSI AKTIVITAS ANTIOKSIDAN PETAI CINA (Leucaena leucocephala L.) Oktaviani, Milla
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.15

Abstract

Antioksidan merupakan suatu molekul untuk melawan radikal bebas yang terdapat dalam tubuh. Tujuan dari review artikel ini adalah untuk memberikan informasi terkait potensi aktivitas antioksidan petai cina. Metode yang digunakan adalah studi pustaka yang diperoleh melalui online dari jurnal nasional dan internasional. Dari hasil penelitian diketahui bahwa kulit, daun dan biji petai cina dimanfaatkan sebagai antioksidan dengan berbagai macam pelarut menggunakan metode DPPH. Aktivitas antioksidan petai cina dikategorikan menurut IC50. Aktivitas antioksidan yang paling kuat terdapat dalam biji petai cina, sedangkan kulit buah petai cina termasuk kedalam kategori kuat dan daun petai cina termasuk kedalam antioksidan yang lemah. Karena potensi sebagai antioksidan, petai cina juga dapat dibuat sediaan farmasi seperti serbuk effervescent.
Literature Review: Waktu Tunggu Obat di Instalasi Farmasi Rumah Sakit Amir, Kemal; Tulak Rerung, Lola'
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.17

Abstract

Prescription service is the patient's final point in the health care process. Therefore, the hospital must pay attention to the processing time for patient prescription services. The waiting time for prescription services is divided into two, namely finished drugs with a time of ≤ 30 minutes and concoction drugs ≤ 60 minutes. This literature review study aims to determine the waiting time for drugs in hospital pharmacy installations. The method used is the Literature Review approach. This study uses a descriptive method in the form of a literature review. A literature search of research journals, scientific articles and journal reviews through google schoolar, researchgate, and garuda portal. This Literature Review study was obtained from research article searches of the last 10 years. 10 journals that meet predetermined inclusion and exclusion criteria. Based on the results of the Literature Review that was carried out, it was found that 7 journals were in accordance with the minimum service standards of the hospital. While 3 journals did not meet the minimum hospital service standards.
FORMULASI DAN UJI SIFAT FISIK LILIN AROMATERAPI KOMBINASI ROSEMARY (ROSMARINUS OFFICINALIS L.) DAN DAUN MINT (MENTHA ARVENSIS) Tulak Rerung, Lola'; Oktaviani, Milla
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.18

Abstract

Essential oils have a distinctive aroma and are volatile. In general, essential oils are used as food flavoring, perfume, cosmetics, aromatherapy and medicine. Rosemary (Rosmarinus Officinalis L.) contains essential oils with the main ingredients being 1,8-cineol, camphor, α-pinene limonene, camphene and linalool which are useful for reducing anxiety and improving memory. Mint leaves (Mentha arvensis) contain menthol which is antiseptic, carminative, cooling, stimulant, diuretic and has a sedative and relaxing effect. This research was conducted to formulate and test the physical properties of a combination of Rosemary (Rosmarinus officinalis L.) and Mint (Mentha arvensis) aromatherapy candles. This research method was experimental with the formulas F1 (1%:1%), F2 (3%:3%), and F3 (5%:5%), then organoleptic tests, burning time tests, and preference tests were carried out. The results showed that all formulas had a distinctive aromatic shape, color, and smell. F2 preparation wax has the longest burning time. The results of the preference test showed that the F2 wax preparation was much liked by the respondents.
A Review MANFAAT PRODUK LEBAH SEBAGAI PENGAWET PADA KOSMETIK: MANFAAT PRODUK LEBAH SEBAGAI PENGAWET PADA KOSMETIK Mustika, Rahayu; Suryani, Ade Irma
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.19

Abstract

Kosmetik atau skin care salah satu produk farmasi yang paling banyak dibicarakan saat ini, tren ini memiliki ruang lingkup yang luas baik usia maupun gender, seiring perkembangan teknologi hampir semua industri kosmetik mengadopsi bahan-bahan alam. Aktivitas antibakteri madu sudah dikenal sejak abad ke-19. Konsentrasi gula yang tinggi, hidrogen peroksida, dan pH rendah adalah faktor antibakteri yang terkenal dalam madu, methylglyoxal dan antimikroba peptida bee defensin-1 diidentifikasi sebagai senyawa antibakteri penting, sehingga madu memiliki potensi besar dijadikan sebagai bahan pengawet alami untuk sediaan kosmetik. Artikel ini akan membahas tentang pemanfaatan madu sebagai agen antibakteri atau pengawet pada sediaan kosmetik.
REVIEW ARTIKEL : POTENSI LIMBAH KULIT NANAS (ANANAS COMOSUS L. MERR) SEBAGAI SHAMPO ANTIKETOMBE Agustina, Putri; Budiyanti, Lia Eka
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.20

Abstract

Shampoo is one of the cosmetics used on hair to treat various problems, one of which is dandruff. Dandruff is the excessive release of dead skin cells on the head which can be accompanied by itching and inflammation of the scalp. Pineapple skin is part of the pineapple that is usually not used and will become waste. The purpose of reviewing this article is to provide information to readers regarding the potential of pineapple peel as an anti-dandruff shampoo. The method used in this research is Literature Review Article by taking literature from Google Scholar, Researchgate and PubMed. Based on the results of the review article, it was found that pineapple peel has the potential as an anti-dandruff shampoo against Candida albicans, Pityrosporum ovale, Trichophyton mentaghrophytes and Malassezia furfur. At a concentration of 25%, pineapple peel extract had an inhibition of 22,73 mm against Trichophyton mentaghrophytes and 24,16 mm against Malassezia furfur.
FORMULASI DAN UJI SIFAT FISIK GEL EKSTRAK ETANOL DAUN MURBEI (MORUS ALBA L.): FORMULASI DAN UJI SIFAT FISIK GEL EKSTRAK ETANOL DAUN MURBEI (MORUS ALBA L.) Ambarsari, Niati; Tulak Rerung , Lola'
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.22

Abstract

The use of plants as medicines in Indonesia has been going on for a long time. One example is mulberry leaves (Morus alba L.) which are traditionally used to treat burns. Mulberry leaf extract (Morus alba L.) contains secondary metabolites such as alkaloids, flavonoids, saponins, tannins and terpenoids. The presence of these contents in mulberry leaves has the potential as anti-inflammatory, antibacterial and antioxidant. This research aims to prepare and test the physical properties of mulberry leaf extract gel (Morus alba L). The extraction method used is maceration. The gel formula is made with three extract concentrations, namely F I (1.5%), F II (2%) and F III (2.5%). The physical properties of the gel include organoleptic tests, pH, homogeneity, adhesion and spreadability. The results of all physical properties tests on formulas I, II and II met the requirements for gel preparations, but the spreadability test for formula I did not meet the requirements for gel preparations. From the results of the physical properties test of the ethanol extract gel of mulberry leaves (Morus alba L.) it can be concluded that formula III is the best and optimal formula.
LITERATURE REVIEW: AKTIVITAS ANTIBAKTERI EKSTRAK DAUN RAMANIA (Bouea macrophylla Griffith) Tulak Rerung, Lola'
Journal of Pharmacy Tiara Bunda Vol. 4 No. 1 (2024): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i1.43

Abstract

The ramania plant (Bouea macrophylla Griffith) is still very limited in its use, however ramania leaves have the potential to control the wound healing process or infection. Infections are generally caused by bacteria such as Staphyloccous aures, Escherichia coli, Actinomyces spp, and many more. This literature review research aims to determine the antibacterial activity of ramania leaf extract (Bouea macrophylla Griffith). The method used in the review process for this article is a narrative review through searching articles that have been published both nationally and internationally. Searching research journal libraries, scientific articles and journal reviews via Google Schoolar, Researchgate, and the Garuda Portal. This literature review study was obtained from article searches. research in the last 10 years. There are 5 journals that meet the specified inclusion and exclusion criteria. Based on the results of the literature review that has been carried out, it was found that ramania/gandaria leaves have potential as an antibacterial treatment. The antibacterial activity in ramania leaves is due to the work activity of the secondary metabolite compounds contained therein, including alkaloids, flavonoids, saponins, steroids, quinones and tannins. Ramania leaves have moderate to strong activity against the bacteria Staphylococcus aureus and Actinomyces spp, while the antibacterial activity of ramania leaves is weak against Escherichia coli.
PENGARUH PEMBERIAN EKSTRAK ETANOL BIJI PAPAYA (CARICA PAPAYA L.) DAN DAUN GANDARUSA (JUSTICIA GANDARUSSA BURN. F.) SERTA KOMBINASINYA TERHADAP KUALITAS SPERMATOZOA MENCIT JANTAN (MUS MUSCULUS) TAHUN 2022 Irma Suryani, Ade
Journal of Pharmacy Tiara Bunda Vol. 3 No. 1 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i1.47

Abstract

Spermatozoa merupakan bentuk sel matur dari sel germinal yang terdapat dalam tubulus seminiferus. Kualitas spermatozoa dapat dilihat dari beberapa parameter seperti konsentrasi, motilitas dan morfologi spermatozoa. Salah satu tanaman yang mempunyai kemampuan untuk memengaruhi kualitas spermatozoa adalah biji tanaman pepaya (Carica papaya L.). Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak biji pepaya (Carica papaya L.) terhadap kualitas spermatozoa terutama konsentrasi, motilitas dan morfologi spermatozoa. Penelitian ini merupakan penelitian yang bersifat studi pustaka (literature review) yang dilakukan dengan cara identifikasi dan interpretasi terhadap semua hasil penelitian tertentu. Literatur diperoleh dari database Pubmed, Sciencedirect, dan Google Scholar. Berdasarkan kriteria inklusi dan eksklusi didapatkan 14 literatur. Semua literatur yang terpilih adalah penelitian bentuk eksperimental. Penelitian ini menunjukkan bahwa dari 14 literatur yang terpilih, 8 literatur yang data hasil penelitiannya memberikan respon bermakna berupa penurunan konsentrasi spermatozoa, 13 literatur yang data hasil penelitiannya memberikan respon bermakna berupa penurunan motilitas spermatozoa dan 12 literatur yang data hasil penelitiannya memberikan respon bermakna berupa penurunan morfologi normal spermatozoa. Simpulan: Ekstrak biji pepaya (Carica papaya L.) memengaruhi kualitas spermatozoa yaitu menurunkan konsentrasi, motilitas dan morfologi spermatozoa
SKRINING FITOKIMIA DAN AKTIVITAS ANTIBAKTERI EKSTRAK AKAR DADANGKAK (HYDROLEA SPINOSA L) TERHADAP BAKTERI Oktaviani, Mila
Journal of Pharmacy Tiara Bunda Vol. 3 No. 1 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i1.48

Abstract

Background: Infectious diseases are still a major problem in the world, especially in developing countries, Indonesia. Objective: To determine the antibacterial activity of dadangkak root extract (Hydrolea spnosa L.) against Sterptococcus mutans bacteria using the disc diffusion and dilution methods to determine the MIC (Minimum Inhibitory Concentration) and KBM (Minimum Kill Concentration) values. Method: Extraction used the maceration method and testing for antibacterial activity used the disc diffusion and dilution methods with concentrations of 20%, 40%, 60%, 80% and 100%. Data analysis uses descriptive qualitative and quantitative. Results: Secondary metabolites produced by dadangakak root extract are: alkaloids, flavonoids, tannins and saponins which have antibacterial activity. The antibacterial activity of Dadangkak root extract (Hydrolea spinosa L.) against Streptococcus mutans bacteria using diffusion testing produced an average inhibition zone of 8.22 mm and using the dilution method to find the MIC was found at a concentration of 40%. Meanwhile, KBM was not found in all concentrations. Conclusion: Dadangkak root extract has secondary metabolites, namely: alkaloids, flavonoids, tannins and saponins. Testing of antibacterial activity using the disc diffusion method showed that there was an inhibitory zone produced, Dadangkak (Hydrolea spinosa L.) root extract had an MIC value at a concentration of 40% against Streptococcus mutans bacteria using the dilution method.

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