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Journal of Pharmacy Tiara Bunda
Published by Politeknik Tiara Bunda
ISSN : -     EISSN : 30323657     DOI : 10.62619
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Journal of Pharmacy Tiara Bunda (JPTB) is an academic journal related to the fields of pharmacy and healthcare, published by an institution named "Tiara Bunda." JPTB serves as a platform for academics, researchers, and professionals in the field of pharmacy to share knowledge, research findings, innovations, and the latest developments in the pharmaceutical industry. The journal aims to provide a venue for exploring various topics in the field of pharmacy, including but not limited to pharmacology, pharmaceutical chemistry, pharmacokinetics, pharmacodynamics, clinical pharmacy, pharmacogenomics, pharmaceutical sciences, drug development, and rational drug use.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 49 Documents
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FORMULASI DAN UJI SIFAT LILIN AROMATERAPI KOMBINASI MINYAK ATSIRI DAUN KEMAFORMULASI DAN UJI SIFAT LILIN AROMATERAPI KOMBINASI MINYAK ATSIRI DAUN KEMANGI (OCINUM SANCTUM L) DAN SEREH (CYMPOGOGON ATRATUSNGI (OCINUM SANCTUM L) DAN SEREH (CYMPOGOGON ATRATUS) Anggraini, Herlina
Journal of Pharmacy Tiara Bunda Vol. 5 No. 1 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In the current conditions of the Covid-19 pandemic, aromatherapy candles have become a necessity for the community as an alternative treatment by utilizing natural ingredients whose popularity is increasing. One of natural ingredients used for aromatherapy is basil and lemongrass. This study aimed to determine whether the essential oil combination of basil leaves (Ocimum sanctum L) and lemongrass (Cymbopogon citratus) can be formulated into aromatherapy candles. The experiment was conducted in the laboratory. The essential oils of basil and lemongrass were gainded from E-Commerce and processed through Thin Layer Chromatography. Silica gel stationary phase, chloroform-benzene mobile phase for basil leaves and toluene-ethyl acetate mobile phase for lemongrass samples. Then the materials (for making aromatherapy candle) were made in three different concentrations of formula I (3%: 20%), formula II (2%: 10%), and formula III (1%: 5%). Test of physical properties of the materials included organoleptic test, test melting point, burn times test and preference test from 20 respondents. The results of the test of the materials for aromatherapy candle showed that there was an affect on the physical properties of aromatherapy candles. Based on the findings of physical properties test, formula III resulted the best because of high melting test point and the longest burning time. Formula I was widely preferred for greater concentration of essential oils
AKTIVITAS HIPOGLIKEMI DARI TEH HERBAL CAMPURAN HERBA SAMBILOTO (Andrographis Paniculata) DAN BIJI MAHONI (Swietenia Mahagoni) DAN PROFIL METABOLIT SEKUNDER TAHUN 2022 Dewi, Hasna
Journal of Pharmacy Tiara Bunda Vol. 2 No. 2 (2022): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.80

Abstract

Diabetes mellitus is a chronic metabolic disorder that continues to present a major world wide health problem. Numerous herbal drugs like Andrographis paniculata and Swietenia mahagoni have been used by people of various cultures to treat diabetes. The aim of this research was to measure the hypoglycemic activity herbal tea of Andrographis paniculata herbs and Swietenia mahagoni seeds and their combination in alloxan- induced diabetic mice. The tea was prepared by brewing 10 g herbal tea with 100 ml of boiling water for 10 minutes. The herbal tea of Andrographis paniculata herbs, Swietenia mahagoni seeds, combination with ratio 1:1, 1:2 and 2:1 (0.4 ml/20 g BW), was administered orally to groups I, II, III, IV and V respectively. The reference drug glibenclamide (0,013 mg/10 g BW) and CMC-Na were also administered orally to animals in positive and negative control group respectively. Oral administration of herbal tea for seven days resulted in a slight reduction in blood glucose level. Statistically there is no groups that has significant difference with negative control groups (P < 0.05) except positive control. Therefore the herbal tea combination of Andrographis paniculata herbs and Swietenia mahagoni seeds with ratio 2:1, showed the biggest reduction in blood glucose level (88.20 ± 43.16 mg/dl). The secondary metabolite profiling was done by establish the TLC and chromatogram profile. TLC profiling was performed out using Chloroform:Methanol (9:1) as mobile phase. Then, TLC plate scanned in wavelength 254 nm and 366 nm using CAMAG TLC Scanner 3.
PEMBUATAN TEH HERBAL DARI DAUN KELAPA SAWIT (ELAEIS GUINEENSIS JACQ) Tulak Rerung, Lola'
Journal of Pharmacy Tiara Bunda Vol. 5 No. 1 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v2i2.82

Abstract

Tea is one drink that is liked and consumed by people all over the world, containing tannin which is believed to be a refreshing and healthy drink. To make oil palm herbal tea, and know the quality standards bioactive components. Palm leaves are separated from the lid, washed thoroughly, drained, cut ± 1 cm. Furthermore, it is placed on a rack and allowed to wither for 14 to 24 hours, then the leaves are blended and oxidized. Then put it in a cool and humid place, for the fermentation process. Furthermore, it is dried in a drying cabinet with a temperature variation of 50 ° C, 90 ° C and 110 ° C with successive times (110, 130, and 150 minutes) then a quality standard test, and screening of herbal tea powder. Quality standard test of oil palm herbal tea smell, taste and color of distinctive brewing water of tea products, cadmium metal contamination (0.303ppm) and lead (0.149ppm), arsenic contamination (<0.0004ppm), microbial contamination with total plate number11.72 ×107,, water content in a row (7.18; 5.88; 3.92%), extract content in water (8.6; 5.96; 5.76%), total ash content (4.3;4.91; 5.26%), water soluble ash content from total ash (4.62; 7.88; 10.09%), acid insoluble ash content (0.75; 0.93 ; 1.17%). Herbal tea powder screening results were positive for triterpenes/steroids, alkaloids, flavonoids, tannins, saponins, and glycosides. The results of flavonoid test results from fresh leaves of palm oil, powder before drying, herbal tea with drying temperature variations of 50°C, 90° C and 110°C with successive times (110, 130, 150 minutes), namely (357.13;265.678; 175.14; 161.28; 176.99 mg / 100)Oil palm leaf herbal tea can be made as an herbal tea and variationsin drying temperature can affect the quality of the oil palm leaf herbal tea
FORMULASI DAN UJI STABILITAS FISIK GEL HAND SANITIZER KOMBINASI EKSTRAK DAUN SIRIH HIJAU (PIPER BETLE) DAN EKSTRAK DAUN KELOR (MORINGA OLEIFERA) SEBAGAI ANTIMIKROBA Anggraini, Herlina
Journal of Pharmacy Tiara Bunda Vol. 2 No. 1 (2022): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i1.83

Abstract

Antiseptics or handsanitizers generally contain alcohol and triclosan which when used continuously can irritate the skin, causing a burning sensation on the skin. One alternative to reduce the chemical content in handsanitizers is to use natural ingredients that contain antimicrobial compounds. Natural ingredients used in this study are betel leaf extract and Moringa leaf. The purpose of this study was to determine the right combination of betel and moringa leaf extract concentrations for a handsanitizer formulation with good physical stability and antimicrobial activity. This research method used a completely randomized design (CRD) with a combination of concentrations, namely FI (25% betel leaf extract and 75% moringa leaf extract), F2 (50% betel leaf extract and 50% moringa leaf extract) and F3 (75% betel leaf extract and 25% Moringa leaves). The results showed that green betel leaf and moringa leaf extracts can be made as hand sanitizer gel preparations with various combinations of concentrations. Hand sanitizer gel of green betel leaf and moringa leaf extract with a concentration of 75% betel leaf extract and 25% moringa leaf extract had the best physical properties and stability
Pengetahuan dan Rasionalitas Pasien Terhadap Pengobatan Sendiri di Apotek Aulia Rahmi, Ika
Journal of Pharmacy Tiara Bunda Vol. 1 No. 1 (2021): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i1.84

Abstract

knowledge about self-medication. This sampling was carried out using the Purposive Sampling method, namely a sampling determination technique based on certain considerations. Data collection took place for two months using a questionnaire instrument as data collection for 90 respondents. Through the primary data obtained in the form of questions distributed to respondents who came to buy medicine at the Pharmacy. The data obtained by collecting the answers to the questionnaire were then tabulated, scored, and presented. Based on the results of the study, it was concluded that the level of public knowledge about self-medication in three Pharmacies, which stated that they knew 77.19%, did not know 14.67%, and did not know 8.12%. So it was concluded that the level of public knowledge about self-medication was included in the high category, namely 77.19%
Formulasi dan Uji Stabilitas Fisik Sediaan Salep Dari Fraksi Daun Kemangi (Ocimun sanctum L) Mustika Sari, Rahayu
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.86

Abstract

This basil plant (Ocimum Sanctum.Lin.) contains: essential oils, alkaloids, eugenol, rosmarinic acid, saponins, flavonoids, tannins and phenols. This study aims to determine the preparation of ointment from the basil leaf fraction that meets the requirements of the physical quality of the preparation and to determine the effect of variations in the ointment base from basil leaves by testing the physical stability of the preparation. This research was conducted using the one-way Anova statistical test followed by the Tukey test and the data were analyzed using Kurskal Wallis and Man Withney then tested for the physical properties and stability of the ointment which included organoleptic tests, homogeneity tests, pH tests, viscosity tests, dispersibility tests, and adhesion test. The results showed that basil leaf extract could be formulated into ointment preparations from the basil leaf fraction (Ocimum Sanctum L) into ointment preparations with various base variations that met the physical quality requirements of the preparation and in this study there was an effect of variations in the ointment base from the basil leaf fraction ( hydrocarbon base, absorption base and water soluble base) based on the physical stability test of the ointment preparation. So it can be concluded that the Basil leaf extracts and fractions can be formulated into ointment preparations (Ocimum Sanctum L) but do not meet the physical quality requirements of the preparation and have the effect of base variations on the ointment preparation
Skrining Aktivitas Antibakakteri Fraksi Kulit Buah Durian (Durio zibhetimus M) Kemal, Amir
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.87

Abstract

A screening study of antibacterial activity of Durio zibethinus M fraction on Escherhicia coli bacteria and Staphylococcus aureus bacteria has been carried out. This study aims to determine the inhibitory effect of durian peel extract on Escherhicia coli bacteria and Staphylococcus aureus bacteria, to determine the most active fraction in inhibiting the growth of Escherhicia coli bacteria and Staphylococcus aureus bacteria and to find out the most active class of compounds against antibacterial activity.The fraction on Duiro zibethinus M was carried out by vacuum liquid chromatography method..Ethyl acetate and methanol extract have antibacterial activity characterized by the presence of clear inhibition zones in the paper disk area, for n-hexane extract does not have a inhibitory effect on bacteria. The results of the inhibition of ethyl acetate extract, which is 17.13 mm are strongly marked for Escherichia coli bacteria and moderate inhibitory capacity of 7.34 mm for Staphylococcus aureus bacteria. Whereas the inhibitory results of methanol extract were 15.11 mm which means that it is strong for Escherichia coli bacteria and strong inhibition power of 11.45 mm for Staphylococcus aureus bacteria. Fraction 2 has antibacterial activity in Staphylococcus aureus bacteria characterized by the presence of clear inhibition zones in the piper disk area, whereas in Escherichia coli bacteria there is no inhibiting fraction. The results of the inhibition of fraction 2 is 9.96 mm which means that it is medium for Staphylococcus aureus bacteria. On the results of identification fractionation of Durio zibethunus M fruit skin showed function as an antibacterial, namely the Flavonoid compound
Uji Aktivitas Antibakteri Ekstrak Daun Kemangi (Ocium sanctum L) terhadap bakteri Patogen dengan metode KLT Bioautografi Dewi, Hasna
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.88

Abstract

A research of the antibacterial activity test extracts of basil (Ocimum sanctum L) against pathogenic bacteria by using KLT Bioautografi. This study aims to determine the activity and basil leaf extract chemical components are on the inhibition of bacterial. Basil (Ocimum sanctum L) extracted by maceration method using ethanol 70%. Extraction then screened for antibacterial activity with levels of 1 mg / ml against microbes that Staphylococcus aureus, Streptococcus mutans, Staphylococcus epidermidis, Salmonella typhi, Bacillus subtillis, Escherichia coli, Pseudomonas aeruginaosa and vibrio sp. Tests showed that 70% ethanol extract of leaves of basil can inhibit the growth of Staphylococcus aureus, Streptococcus mutans, Salmonella typhi, Bacillus subtillis, Escherichia coli, Pseudomonas aeruginaosa and vibrio coma. Testing TLC-Bioautografi basil leaves ethanol extract using ethyl acetate eluent: n-hexane (1: 3) showed inhibition of bacteria at Rf values of 0.15, 0.31, 0.44. Identification test showed that the compounds provide antibacterial flavonoids, alkaloids and terpenoids
Skrining Fitokimia dan Uji Aktivitas Antioksidan dengan Metode DPPH Ekstrak Benalu Pohon Mahoni (Loranthus sweietenia macrophylla) Oktaviani, Mila
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.89

Abstract

Mahogany tree (Swietienia macrophylla king) has many benefits as an antioxidant, starting from the roots, bark, leaves, even the mistletoe that lives on this plant. Mahogany mistletoe leaves (Loranthus swietenia macrophylla) were used as samples in this study to test their antioxidant activity. This study was conducted because many have conducted antioxidant tests on mistletoe leaves such as mengkudu mistletoe leaves, coffee mistletoe leaves, mango mistletoe leaves and kersen mistletoe leaves. Mahogany mistletoe leaves (Loranthus swietenia macrophylla) were used as samples in this study to test their antioxidant activity. Before the antioxidant activity test was carried out, a phytochemical screening test was first carried out as a qualitative analysis stage to determine the secondary metabolite content in mahogany mistletoe leaves. Mahogany mistletoe leaves were dried in variations of 0 days (S), 4 days (KA4), and 8 days (KA8) which were extracted by maceration with 96% ethanol solvent. The results of the phytochemical screening test showed that mahogany mistletoe leaf extract contains secondary metabolite compounds such as flavonoids, phenolics, alkaloids, saponins, terpenoids, and steroids. The total phenolic content was 25.25; 48.29; and 52.82 mgGEA/g extract for extracts S, KA4, and KA8, respectively. Furthermore, the antioxidant activity test using vitamin C as a comparator with the DPPH (2,2-Diphenyl-1-picrylhydrazyl) method showed IC50 values ​​of 10.79; 8.00; 7.41 ppm for extracts S, KA4, and KA8, respectively, indicating that the highest antioxidant activity was possessed by sample KA 8 with an IC50 value of 7.41 ppm with a total phenolic content of 52.82 mgGEA/g
THE INFLUENCE OF ELECTRONIC PRESCRIPTIONS ON PRESSRIBING ERROR IN THE CLINIC X JAKARTA PHARMACY INSTALLATION: PENGARUH RESEP ELEKTRONIK TERHADAP PRESCRIBING ERROR DI INSTALASI FARMASI KLINIK X JAKARTA Ambarsari, Niati; Kadek Dwi Parwati, Ni
Journal of Pharmacy Tiara Bunda Vol. 4 No. 2 (2024): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.90

Abstract

Electronic prescriptions play a role in preventing medication errors, which means failures in the treatment process that have the potential to result in harm and endanger the patient. Prescribing errors are errors in drug selection, such as errors in dosage, quantity, indications and contraindications for treatment. This study aims to determine the effect of electronic prescriptions on prescribing errors in improving pharmaceutical services at clinic X Jakarta. The research method used was descriptive research with a random sampling technique, using 250 electronic prescriptions and 250 manual prescriptions in January – May 2023. The results of the study showed prescribing errors in electronic prescriptions, namely 15 prescriptions (no dose (2%), incorrect instructions). usage (2%), no dosage form(2%)). In manual prescriptions, 41 prescribing errors occurred (unclear writing (2%), no patient name (2%), no weight (1.6%), no medication dose (2.8%), no exact instructions for use (2%), no dosage form (2%), no patient age (4%), no prescription date (2%)). The conclusion from this research is that the use of electronic prescriptions in clinic X Jakarta has a very big influence on prescribing errors. Of the 250 manual prescriptions and 250 electronic prescriptions, the largest prescribing error was found, namely 41 prescriptions (18.40%) for manual prescriptions, while only 15 prescription errors for electronic prescriptions (6%).

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