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INDONESIA
Journal of Pharmacy Tiara Bunda
Published by Politeknik Tiara Bunda
ISSN : -     EISSN : 30323657     DOI : 10.62619
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Journal of Pharmacy Tiara Bunda (JPTB) is an academic journal related to the fields of pharmacy and healthcare, published by an institution named "Tiara Bunda." JPTB serves as a platform for academics, researchers, and professionals in the field of pharmacy to share knowledge, research findings, innovations, and the latest developments in the pharmaceutical industry. The journal aims to provide a venue for exploring various topics in the field of pharmacy, including but not limited to pharmacology, pharmaceutical chemistry, pharmacokinetics, pharmacodynamics, clinical pharmacy, pharmacogenomics, pharmaceutical sciences, drug development, and rational drug use.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 49 Documents
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POTENSI BAHAN ALAM BAWAH LAUT SEBAGAI OBAT ALAMI UNTUK PENGOBATAN DIABETES Agustina, Putri
Journal of Pharmacy Tiara Bunda Vol. 4 No. 2 (2024): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.93

Abstract

The potential of underwater natural materials has attracted the attention of researchers and health professionals as an effective source of natural remedies for the treatment of diabetes. Several examples of polyphenol compounds found in underwater natural materials have the ability to act as antioxidants, so they are widely used to improve the condition of diabetic patients. Polyphenols have the ability to suppress postprandial hyperglycemia by inhibiting the hydrolysis activity of enzyme carbohydrates, inhibiting glucose transport in the blood, affecting the function of cells β pancreas, and glucose absorption tissue. The method used in this writing is literature review using international and national journals that are in accordance with the purpose of writing. Thus, the potential of underwater natural ingredients as a natural remedy for diabetes treatment is very promising and needs to be further examined and developed to improve the quality of life of diabetics.
Perbandingan Efektivitas Paracetamol dan Ibuprofen untuk Terapi Penurun Demam pada Usia 6 Bulan sampai 18 Tahun di RSUD Kota Depok periode Juni 2023 sampai Juni 2024 Rahayu, Mustika; Ambarsari, Niati; Fadilah, Nur
Journal of Pharmacy Tiara Bunda Vol. 4 No. 2 (2024): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.103

Abstract

Fever has been noted as a precursor or characteristic of the disease. Conditions that aggravate fever often result in therapeutic failure or a poor prognosis. This study aims to analyze the comparison of single therapy administration of Paracetamol, Ibuprofen and a combination of both in treating fever and/or pain in patients aged 6 months to 18 years. The results of the study showed that using Ibuprofen alone was better at reducing fever in the first 4 hours than Paracetamol alone, however, the combination therapy of the two was not much different from using Ibuprofen alone. To treat pain accompanied by fever, using Ibuprofen alone has been proven to provide a longer pain-free period compared to using Paracetamol alone, and the combination of the two is not much different from Ibuprofen
Analisis Tingkat Kepuasan Pelanggan Terhadap Pelayanan Kefarmasian Model SERVQUAL di Apotek X Kota Belitang Subagiyo, Ahmad; Aulia, Rina
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.243

Abstract

Pelayanan kefarmasian di apotek merupakan tolok ukur mutu pelayanan kesehatan yang diberikan. Kepuasan pelanggan menjadi indikator penting dalam evaluasi dan perbaikan mutu pelayanan. Penelitian ini bertujuan mengetahui tingkat kepuasan pelanggan terhadap pelayanan kefarmasian di apotek berdasarkan lima dimensi SERVQUAL: kehandalan, ketanggapan, empati, jaminan, dan bukti fisik. Penelitian ini menggunakan metode deskriptif kuantitatif dengan teknik quota sampling pada 82 pelanggan yang berkunjung pada Juni–Juli 2024 dan memenuhi kriteria inklusi. Data dikumpulkan menggunakan kuesioner skala Likert dan dianalisis secara univariat. Hasil penelitian menunjukkan bahwa pelanggan merasa sangat puas pada semua dimensi: kehandalan (4,58), ketanggapan (4,55), empati (4,41), jaminan (4,40), dan bukti fisik (4,65), dengan skor rata-rata keseluruhan 4,40 (kategori puas). Hasil ini menunjukkan bahwa mutu pelayanan di apotek tergolong baik, namun peningkatan pada dimensi empati dan jaminan tetap diperlukan untuk lebih meningkatkan pengalaman pelanggan.
FORMULASI DAN EVALUASI SEDIAAN KOSMETIK LIP BALM DARI EKSTRAK DAUN PACAR AIR (IMPATIENS BALSAMINA L.) Dayanti, Rahma
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.249

Abstract

Bibir sangat rentan terhadap pengaruh lingkungan serta berbagai produk perawatan kesehatan, kosmetik dan produk produk perawatan kulit lainnya yang dapat menyebabkan kerusakan kulit bibir yaitu bibir menjadi kering dan pecahpecah juga menimbulkan rasa nyeri dan tidak nyaman. Untuk menyembukan penyakit bibir seperti pecah atau kering dan agar terlihat lebih lembab maka dibutuhkan pengobatan salah contohnya adalah ekstrak daun pacar air yang diformulasi dalam bentuk lip balm. Penelitian ini bertujuan untuk mengetahui bahwa ekstrak daun pacar air (Impatients balsamina L) bisa dapat dimanfaatkan sebagai pewarna alami pada sediaan lip balm. Simplisia pada daun pacar air diekstrak menggunakan metode maserasi dengan pengujian skrining fitokimia dan uji evaluasi sediaan lip balm. Hasil yang diperoleh pada penelitian bahwa ektrak daun pacar air bisa dijadikan pewarna alami pada sediaan lip balm dan hasil formulasi F1,F2,dan F3 yang menghasilkan formulasi yang paling baik adalah F3 dengan konsentrasi sebesar 15 %
SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN KAPUK (CEIBA PENTANDRA (L.) GAERTN) TERHADAP BAKTERI ESCHERICIA COLI Al Zahra, Siskha
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.250

Abstract

ABSTRAK Kapuk (Ceiba pentandra (L.) Gaertn) merupakan salah satu tanaman asli Indonesia yang sudah dikenal sejak lama. Diketahui kandungan senyawa aktif dalam daun kapuk diyakini mengatasi demam, diare, diabetes, hipertensi, sakit kepala, obat luka, dan astringen ( menyerap air ) yang dapat membantu menghentikan diare Banyak manfaat yang dirasakan oleh masyarakat dengan adanya tanaman obat, bahkan tanaman obat dapat menjadi salah satu alternatif yang dapat menyebuhkan berbagai macam penyakit yang sangat ekonomis. Penelitian bertujuan untuk mengetahui kandungan fitokimia ekstrak etanol daun kapuk dan pengaruh berbagai konsentrasi ekstrak etanol dau kapuk terhadap pertumbuhan bakteri E-coli. Metode kerja yang digunakan yaitu pembuatan simplisia, ekstraksi, skrining fitokimia, pengujian aktivitas antibakteri berdasarkan diameter zona hambat menggunakan metode difusi cakram. Berdasarkan dari hasil penelitian yang telah dilakukan bahwa ekstrak daun kapuk mempunyai kandungan senyawa metabolit sekunder yang memiliki aktivitas antibakteri, seperti: alkaloid, flavonoid, tanin, dan saponin. Ekstrak daun kapuk juga memiliki kemampuan antibakteri terhadap bakteri E-coli yang diperolehnya nilai kategori lemah. Pada konsentrasi 20 %, 40 %, 50 %, dan nilai kontrol positif nilai konsentrasi hambat minimum pada ekstrak daun kapuk ditemukan. Sedangkan, pada nilai kontrol negatif tidak ditemukan.
ANALISIS PENAMBATAN SENYAWA CHARANTIN DARI BUAH PARE (Momordica charantia) PADA GLUCOSE TRANSPORTER 3 (GLUT3) Ilmia, Nisrien
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.256

Abstract

Glucose transporters have an important role in the body to transport blood sugar to other organs. In patients with diabetes mellitus, the signaling of GLUT, especially class 1, is reduced because it is affected by impaired insulin secretion. Bitter gourd is thought to have an anti-diabetic effect by lowering blood pressure, with the main component in it being charantin. Purpose: This study aims to determine the activity of charantin as a blood sugar lowering agent by inducing GLUT3 through a compound anchoring test. Methods: The type of research in this study was a computer-based experimental study using an in silico test or molecular docking by comparing the charantin test ligand and the native ligand as a comparison in the form of Octyl Glucose Neopentyl Glycol. Conclusion: The results of the compound anchoring test show that the binding energy (ΔG) affinity of charantin for GLUT3 is -7.5 Kcal/mol, while for Octyl Glucose Neopentyl Glycol it is -6.15 Kcal/mol, and charantin has activity like Octyl Glucose Neopentyl Glycol with amino acid residues that bind to the active site of the GLUT3 protein, namely AGR228. This indicates that the compounds present in bitter gourd can be predicted to be used as therapy for diabetes mellitus patients.
ANALISIS POLIFARMASI SERTA HUBUNGAN POTENSI INTERAKSI OBAT TERHADAP GLUKOSA PASIEN GERIATRI Dewi, Hasna; Agustiansyah, Lukidita; Dian Andini
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.255

Abstract

Diabetes mellitus is achronic metabolic disease that requires long-term treatment. Elderly people with multimorbidity often use multiple medications, known as polypharmacy, which can increase the risk of drug interactions. This study aims to analyze polypharmacy prescriptions and determine the relationship between drug interactions and blood glucose levels in geriatric patients with type2 diabetes. This study is non-experimental with a descriptive-analytical design through a retrospective cross-sectional approach. Sampling used random sampling in the form of medical records of171 geriatric patients with type 2 diabetes. Using univariate and bivariate analysis in the form of chi-square statistical tests with a significance level of<0.05. The results showed that the incidence of type 2 diabetes in geriatric women was higher than in men at119 (69.59%), with the largest distribution of geriatric patients in the 60-69 year age range (77.77%). Based on polypharmacy prescriptions, the most common type of polypharmacy encountered was minor polypharmacy (5-9 drugs)(95.3%), and 159 patients (92.98%) had the potential for interactions. Based on the mechanism pattern, pharmacodynamic interactions occurred in413 cases (74.95%), with the most common level of interaction severity being moderate, occurring in340 cases (61.7%). Chi-square test results showed a relationship between potential drug interactions and blood glucose levels, with p-value of 0.000<0.005.
HUBUNGAN TINGKAT PENDIDIKAN DENGAN PERILAKU PENGGUNAAN OBAT RASIONAL Amir Kemal Sidiq
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.275

Abstract

This study analyzes the correlation between education level and rational drug use behavior among communities in East Jakarta. The objective was to determine whether higher levels of education are associated with better understanding and implementation of rational drug use. A cross‑sectional design was employed using structured questionnaires and simple random sampling. The results showed a significant positive relationship between education level and rational drug use practices. Respondents with higher education demonstrated better knowledge, attitudes, and behavior in using medicines appropriately. These findings highlight the importance of health education and literacy programs to improve rational drug practices in the community
ANALISA DRUG RELATED PROBLEM PADA ENDOMETRIOSIS DI PUSKESMAS DUREN SERIBU PERIODE 1 JANUARI - 30 JUNI 2025 Mustika Sari, Rahayu; Ambarsari, Niati
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.276

Abstract

This study analyzed the incidence of drug-related problems, including adverse events and medical errors, and possible associated risk factors, in patients with endometriosis who used combined oral contraceptives (COCs) and progestins. Reports were collected between January 1, 2024, and June 30, 2025, regarding endometriosis patients in the Medical Record System at the Duren Seribu Community Health Center, Depok City. A disproportionate analysis was performed using the Gamma–Poisson Shrinker model to detect overreported drug–event pairs. Logistic regression analysis was used to explore potential risk factors. There were 23 reports regarding long-term hormonal treatment and 45 reports regarding other medications used for endometriosis. Long-term hormonal treatment included: 15 reports (22.0%) of combined oral contraceptives (COCs), 10 reports (14.7%) of oral progestins, 8 reports (11.76%) of injectable (depot) progestins, 23 reports (33.82%) of progestin-releasing IUDs, and 12 reports (17.64%) of progestin-only implants. Both combined oral contraceptives (COCs) and progestin-only products are relatively safe for patients with endometriosis. Combination therapy (polytherapy) has been negatively associated with several medical errors in COC users, while patients aged ≥30 years have had more pulmonary embolism cases but fewer reported product-related problems.

Page 5 of 5 | Total Record : 49

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