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Ahmad Rayhan
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INDONESIA
Journal of Health and Medicine
Published by Yayasan Penelitian dan Pengabdian Masyarakat Sisi Indonesia
ISSN : -     EISSN : 30646472     DOI : https://doi.org/10.69836/medical-jkk
Core Subject : Health,
Dentistry Medicine & Pharmacology Nursing Public Health Veterinary
Medical : Journal of Health and Medicine - e-ISSN: 3064-6472 (online) is a journal published by Yayasan Penelitian dan Pengabdian Masyarakat Sisi Indonesia with the aim of developing research that focuses on Health, Public Health and Medicine. Focus and Scope: Health Science, Public Health, Public Health Policy, Medical Science, Health Law, Medical Law, Etc. The journal is published in June and December
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 44 Documents
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Ethnobotanical Survey and Literature Review of Phytochemistry and Bioactivity of Medicinal Plants, Cianjur, West Java Yayang Lupita; Zuraida Sagala; Sylvia Rizky Prima; Yelfi Anwar; Purwati
Medical : Jurnal Kesehatan dan Kedokteran Vol 3 No 1 (2026): Januari-Juni 2026
Publisher : Yayasan Penelitian dan Pengabdian Masyarakat Sisi Indonesia

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Abstract

Cianjur Regency, West Java, Indonesia, possesses rich biodiversity and traditional knowledge of medicinal plants that has been transmitted across generations. However, the scientific documentation of local medicinal plant use, phytochemical constituents, and biological activities remains important for supporting the safe and evidence-based development of traditional medicines. This study aimed to identify medicinal plant species used by traditional healers, document the plant parts utilized and preparation methods, and review their reported phytochemical constituents and bioactivities based on scientific literature. A descriptive, cross-sectional ethnobotanical survey was conducted from January to July 2026 in nine villages across the Cipanas, Tanggeung, and Cibinong subdistricts. Primary data were collected through semi-structured interviews with nine traditional healers selected using snowball sampling. Plant specimens were collected and identified through herbarium preparation, while secondary information was obtained through a structured literature review using Google Scholar, PubChem, PubMed, and ScienceDirect. Quantitative ethnobotanical analysis employed the Use Value (UV), Relative Frequency of Citation (RFC), and Relative Importance (RI) indices to determine the cultural significance of each species. The study documented thirteen medicinal plant species belonging to ten botanical families. Leaves were the most frequently utilized plant parts, accounting for 53.85%, followed by rhizomes and tubers at 15.38% each, while flowers and roots accounted for 7.69% each. Orthosiphon aristatus (cat’s whiskers) and Curcuma longa (turmeric) recorded the highest UV, RFC, and RI values, indicating their prominent roles in local traditional healthcare practices. The literature review identified various reported bioactivities, including antioxidant, anti-inflammatory, antibacterial, antidiabetic, and antimicrobial effects. Although several traditional applications were consistent with published scientific findings, certain uses lacked direct supporting evidence and require further investigation. This study provides a documented foundation for preserving ethnomedicinal knowledge, prioritizing medicinal plants for further pharmacological research, and developing standardized, safe, and evidence-based herbal preparations. Further phytochemical, toxicological, and clinical studies are recommended to establish their safety and therapeutic efficacy.
Evaluation of Antihypertensive Drug Use in Chronic Kidney Disease Patients Undergoing Hemodialysis at Cempaka Putih Islamic Hospital, Central Jakarta January-March 2026 Elma Fania Agus; Satya Canda Indra Yanih
Medical : Jurnal Kesehatan dan Kedokteran Vol 3 No 1 (2026): Januari-Juni 2026
Publisher : Yayasan Penelitian dan Pengabdian Masyarakat Sisi Indonesia

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Abstract

Hypertension is one of the leading causes of chronic kidney disease (CKD) progression and is highly prevalent among patients undergoing hemodialysis. Appropriate antihypertensive therapy is essential to control blood pressure, delay disease progression, and reduce cardiovascular complications. Objective: This study aimed to evaluate the use of antihypertensive drugs in chronic kidney disease patients undergoing hemodialysis at Cempaka Putih Islamic Hospital, Central Jakarta, during January–March 2026. Methods: This study employed a descriptive retrospective design using medical record data of CKD patients undergoing hemodialysis. Patient characteristics, antihypertensive drug utilization, and the rationality of therapy were evaluated based on the parameters of appropriate patient, appropriate indication, appropriate drug, and appropriate dose according to the JNC VIII guideline. Results: The evaluation demonstrated that antihypertensive therapy in CKD patients was generally appropriate. The most frequently prescribed antihypertensive agents included candesartan, bisoprolol, amlodipine, clonidine, furosemide, Adalat Oros®, and spironolactone. Assessment of rational drug use showed 100% appropriate patient, 100% appropriate indication, 95.29% appropriate drug selection, and 91.76% appropriate dosage. Conclusion: Antihypertensive therapy among chronic kidney disease patients undergoing hemodialysis at Cempaka Putih Islamic Hospital was predominantly rational according to the JNC VIII guideline. Nevertheless, several cases of inappropriate drug selection and dosing were identified, indicating the need for continuous evaluation to optimize therapeutic outcomes and improve patient safety.
Potential Drug–Drug Interactions and Associated Factors among Outpatients with Coronary Heart Disease at Cempaka Putih Islamic Hospital, Jakarta Lia Ayu Lestari; Widya Handayani
Medical : Jurnal Kesehatan dan Kedokteran 2026: Special Issue
Publisher : Yayasan Penelitian dan Pengabdian Masyarakat Sisi Indonesia

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Abstract

Coronary heart disease (CHD) is a major cause of morbidity and mortality worldwide, and its pharmacological management often involves multiple medications that may increase the risk of potential drug–drug interactions (pDDIs). This study aimed to describe the profile of pDDIs and evaluate their associations with age, gender, number of medications, and comorbidities among outpatients with CHD at Jakarta Cempaka Putih Islamic Hospital. An analytical observational study with a retrospective cross-sectional design was conducted using medical records of 200 outpatients treated between January and March 2026. Total sampling was applied to eligible patients with complete medical records and concurrent use of at least two medications. Potential drug interactions were identified using Drugs.com and Medscape, while descriptive and bivariate analyses were performed using SPSS. Of the 200 patients, 190 (95.0%) had at least one potential drug interaction, with 848 drug-pair occurrences identified. Pharmacodynamic interactions predominated, accounting for 713 occurrences (84.1%), while pharmacokinetic interactions accounted for 135 (15.9%). Most interactions were classified as moderate in severity (782; 92.2%), followed by major (38; 4.5%) and minor interactions (28; 3.3%). Bisoprolol and candesartan constituted the most frequently identified interacting drug pair, with 68 occurrences (8.02%). Bivariate analysis revealed no statistically significant associations between pDDIs and age (p = 0.499), gender (p = 1.000), or number of medications (p = 0.603). However, cardiovascular disorders (p < 0.001) and other comorbidities (p = 0.017) were significantly associated with pDDIs, whereas hypertension, diabetes mellitus, dyslipidemia, and renal disorders were not. These findings demonstrate the high prevalence of potential drug interactions among CHD outpatients and emphasize the importance of routine medication review, systematic interaction screening, and appropriate clinical monitoring. Collaborative pharmaceutical care is essential to support rational prescribing and improve medication safety.
Effectiveness Of Pharmaceutical Interventions In Type 2 Diabetes Mellitus: A Systematic Review Vintha Sari Uly; Yelfi Anwar
Medical : Jurnal Kesehatan dan Kedokteran Vol 3 No 1 (2026): Januari-Juni 2026
Publisher : Yayasan Penelitian dan Pengabdian Masyarakat Sisi Indonesia

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Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder whose global burden continues to rise, placing considerable pressure on patients and healthcare systems. Successful therapeutic outcomes in Type 2 Diabetes Mellitus (T2DM) are largely contingent upon patient compliance with prescribed regimens and robust self-management practices. However, suboptimal medication adherence remains a persistent barrier to achieving glycemic targets and preventing complications. To enhance medication adherence and clinical indices, diverse pharmaceutical strategies encompassing telepharmacy, structured patient counseling, health education, and ongoing medication therapy monitoring are frequently implemented by pharmacists. A systematic literature review was conducted to evaluate the influence of pharmaceutical interventions on medication adherence and clinical outcomes in patients diagnosed with Type 2 Diabetes Mellitus (T2DM). Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, this study examined peer-reviewed articles published from 2019 to 2026. A rigorous bibliographic search was executed across prominent national and international electronic repositories, namely PubMed, ScienceDirect, Google Scholar, and SINTA. Identified records were screened by title and abstract, followed by full-text assessment against predefined eligibility criteria, and data from the included studies were extracted and synthesized qualitatively. The findings indicate that pharmaceutical strategies such as pharmaceutical care, patient counseling, home pharmacy care, telepharmacy, and health education consistently enhance glycemic regulation, therapeutic compliance, and overall quality of life, while simultaneously mitigating the frequency of drug-related problems (DRPs). Ultimately, current literature validates the effectiveness of pharmaceutical interventions in improving clinical parameters and medication adherence among individuals diagnosed with Type 2 Diabetes Mellitus (T2DM), underscoring the necessity for the broader integration of patient-centered pharmaceutical care to secure long-term clinical success.

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