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Contact Name
Adam Mudinillah
Contact Email
adammudinillah@staialhikmahpariangan.ac.id
Phone
+6285379388533
Journal Mail Official
adammudinillah@staialhikmahpariangan.ac.id
Editorial Address
Jorong Kubang Kaciak Dusun Kubang Kaciak, Kelurahan Balai Tangah, Kecamatan Lintau Buo Utara, Kabupaten Tanah Datar, Provinsi Sumatera Barat, Kodepos 27293.
Location
Kab. tanah datar,
Sumatera barat
INDONESIA
Journal of Biomedical and Techno Nanomaterials
ISSN : 30481120     EISSN : 30481155     DOI : 10.70177/jbtn
Core Subject : Science,
Journal of Biomedical and Techno Nanomaterials is an international forum for the publication of peer-reviewed integrative review articles, special thematic issues, reflections or comments on previous research or new research directions, interviews, replications, and intervention articles - all pertaining to the research fields of medicine, pharmaceuticals, biomaterials, biotechnology, diagnosis and prevention of diseases, biomedical devices, bioinformatics, and all other related fields of biomedical and life sciences. All publications provide breadth of coverage appropriate to a wide readership in Biomedical and Techno Nanomaterials research depth to inform specialists in that area. We feel that the rapidly growing Journal of Biomedical and Techno Nanomaterials community is looking for a journal with this profile that we can achieve together. Submitted papers must be written in English for initial review stage by editors and further review process by minimum two international reviewers.
Articles 66 Documents
NUCLEIC ACID AND PROTEIN-BASED NANOTHERAPEUTICS FOR PRECISION MEDICINE Adwoa Agyemang; Samuel Bediako; Kwame Mensah
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3961

Abstract

Nucleic acid and protein-based nanotherapeutics have emerged as revolutionary approaches in the field of precision medicine, offering highly targeted treatments for various diseases, including cancer, genetic disorders, and viral infections. Traditional therapies often face challenges such as off-target effects, limited bioavailability, and inadequate therapeutic outcomes. Nanotechnology, leveraging the unique properties of nucleic acids (DNA/RNA) and proteins encapsulated in nanomaterials, provides solutions to these limitations by enabling controlled drug release, targeted delivery, and enhanced therapeutic efficacy. This study explores the potential of nucleic acid and protein-based nanotherapeutics in precision medicine, focusing on their mechanisms, applications, and future prospects. The research employs in vitro and in vivo models to evaluate the delivery efficiency, biocompatibility, and therapeutic effectiveness of these nanotherapeutics. The results indicate that nucleic acid-based nanoparticles, such as siRNA and DNA, show significant efficacy in gene silencing and expression modulation, while protein-based nanocarriers demonstrate enhanced targeting of specific cells and tissues. In conclusion, nucleic acid and protein-based nanotherapeutics offer promising advances in precision medicine, providing a new paradigm for treating diseases with high specificity and reduced side effects.
NANOFABRICATION STRATEGIES FOR ARTIFICIAL CELLS, TISSUES, AND ORGANS Silva Fitri; Miku Fujita; Daiki Nishida
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.4073

Abstract

Nanofabrication techniques have emerged as pivotal tools in the creation of artificial cells, tissues, and organs, which hold the potential to revolutionize regenerative medicine and organ transplantation. The ability to precisely engineer materials at the nanoscale allows for the replication of biological structures, enabling the development of functional tissue replacements and therapeutic devices. Traditional methods in tissue engineering often face challenges in mimicking the complexity of natural tissues and organs, leading to suboptimal functionality and biocompatibility. This study investigates various nanofabrication strategies used in the development of artificial cells, tissues, and organs, with an emphasis on their applications in biomedical fields. The main objective of this research is to assess the effectiveness of different nanofabrication approaches, such as 3D printing, self-assembly, and nanolithography, in replicating the architecture and functionality of human tissues. In vitro and in vivo models are employed to evaluate the biocompatibility, structural integrity, and functional performance of fabricated constructs. The results indicate that nanofabricated systems show significant promise in replicating the mechanical, biochemical, and cellular properties of natural tissues. In conclusion, nanofabrication offers an innovative approach to the creation of functional artificial tissues and organs, which could significantly impact the future of medical treatments, particularly in tissue regeneration and transplantation.
ADVANCED NANOCARRIERS FOR CONTROLLED DRUG AND GENE DELIVERY IN CHRONIC DISEASES Ren Suzuki; Daiki Nishida; Nila Trisna Yulianti
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3585

Abstract

Chronic diseases such as cancer, cardiovascular diseases, and neurodegenerative disorders pose significant treatment challenges due to their complexity and resistance to conventional therapies. Nanocarriers, as advanced drug and gene delivery systems, offer a promising solution to address these challenges by providing controlled release, improved targeting, and enhanced therapeutic efficacy. The ability to design nanocarriers that are biocompatible, stable, and capable of precise targeting to diseased tissues holds potential for revolutionizing the treatment of chronic diseases. This study aims to explore the design, development, and evaluation of advanced nanocarriers for controlled drug and gene delivery in chronic diseases. The research focuses on evaluating the efficacy of various nanocarriers, including liposomes, dendrimers, and nanoparticles, in improving drug bioavailability, targeting precision, and therapeutic outcomes in chronic disease models. The research utilizes in vitro cell culture studies and in vivo animal models to assess the effectiveness of different nanocarriers. Characterization techniques, including dynamic light scattering (DLS), transmission electron microscopy (TEM), and drug release assays, are used to evaluate the properties and performance of the nanocarriers. The study demonstrates that advanced nanocarriers significantly improve drug delivery efficiency, reduce systemic toxicity, and enhance therapeutic outcomes in chronic disease models. Gene delivery using nanocarriers also shows promising results in terms of targeted therapy. Advanced nanocarriers are a promising tool for controlled drug and gene delivery, offering potential breakthroughs in the treatment of chronic diseases by improving precision and minimizing side effects.
BIODEGRADABLE NANOMATERIALS FOR TISSUE ENGINEERING AND REGENERATIVE MEDICINE APPLICATIONS Fitriani Fitriani; Khalid Al Ansari; Sarah Al Sabih
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i2.3642

Abstract

The field of tissue engineering and regenerative medicine has seen significant advancements with the use of nanomaterials, particularly biodegradable nanomaterials, which offer promising solutions for tissue regeneration and repair. These materials, due to their biocompatibility, biodegradability, and ability to mimic the extracellular matrix, play a crucial role in supporting cell growth, tissue development, and healing processes. Despite these promising properties, challenges remain regarding the optimization of nanomaterial performance, including controlled degradation rates and tissue-specific responses. This study aims to explore the potential of biodegradable nanomaterials in tissue engineering and regenerative medicine, focusing on their applications, properties, and functional enhancements through design optimization. The research aims to evaluate the efficacy of these nanomaterials in promoting tissue regeneration in various models, including bone, cartilage, and soft tissues. The study involves the synthesis and characterization of biodegradable nanomaterials, including nanofibers, nanoparticles, and hydrogels. In vitro cell culture assays and in vivo animal models are used to assess cell viability, proliferation, differentiation, and tissue regeneration potential. The study demonstrates that biodegradable nanomaterials significantly promote cell proliferation and differentiation, accelerating tissue repair and regeneration in all tested models. Controlled degradation rates of the nanomaterials contributed to sustained cell support and tissue integration. Biodegradable nanomaterials hold substantial promise for advancing tissue engineering and regenerative medicine, offering effective and sustainable solutions for tissue repair and regeneration.
NANOPARTICLE-BASED BIOMARKERS FOR EARLY DIAGNOSIS AND PROGNOSIS OF CANCER Omar Khan; Amir Raza; Dito Anurogo
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 3 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i3.3843

Abstract

Nanoparticle-based biomarkers have shown great potential for the early diagnosis and prognosis of cancer, offering enhanced sensitivity and specificity compared to traditional diagnostic methods. The use of nanoparticles as carriers for biomolecules enables the detection of low-abundance biomarkers in the bloodstream, facilitating the identification of cancer at its early stages when treatment options are more effective. This study investigates the development and application of nanoparticle-based biomarkers for improving cancer detection and prognosis. The primary objective of this research is to evaluate the diagnostic and prognostic capabilities of nanoparticle-functionalized biomarkers in detecting various types of cancer. In vitro assays, animal models, and clinical sample analysis were employed to assess the binding affinity, detection sensitivity, and prognostic value of these biomarkers. The results indicate that nanoparticle-based biomarkers significantly enhance the detection of specific cancer markers, achieving high sensitivity and specificity, particularly in detecting early-stage cancer. Additionally, these biomarkers show promise in predicting tumor progression and patient outcomes. In conclusion, nanoparticle-based biomarkers represent a promising tool for the early diagnosis and prognosis of cancer, with the potential to improve clinical decision-making and treatment outcomes by enabling timely interventions.
NANOTOXICOLOGY AND BIOINTERACTION ASSESSMENT OF BIOMEDICAL NANOMATERIALS Ivan Dimitrov; Maria Ivanova; Muntasir Muntasir
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 3 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i3.3962

Abstract

Biomedical nanomaterials have garnered significant attention for their potential applications in medical diagnostics, drug delivery, and therapeutic interventions. However, concerns regarding their toxicity and biointeraction with biological systems remain largely unaddressed. Understanding the safety and biological interactions of these materials is crucial for ensuring their efficacy and safety in clinical settings. The aim of this study was to assess the nanotoxicological properties of biomedical nanomaterials and their interactions with biological systems. The research focused on evaluating the cytotoxicity, genotoxicity, and immunotoxicity of various nanomaterials commonly used in biomedical applications. A combination of in vitro and in vivo assays was employed to assess the toxicological profile of biomedical nanomaterials. These included cell viability tests, oxidative stress analysis, DNA damage assays, and immune response evaluations. The interactions between nanomaterials and cellular components were also examined using advanced imaging and spectroscopy techniques. The findings indicated that the toxicity of nanomaterials varied depending on their size, surface charge, and composition. Certain nanomaterials demonstrated significant cytotoxic and genotoxic effects, while others showed minimal toxicity. The biointeractions were also influenced by the concentration and exposure duration. The study underscores the need for comprehensive toxicity assessments of biomedical nanomaterials to ensure their safe application in medical technologies. Further research is required to optimize their safety profiles for clinical use.