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ISTA Online Technologi Journal
Published by Institut Sains dan Teknologi Al-Kamal
ISSN : 20883315     EISSN : 27457206     DOI : https://doi.org/10.62702/ion.v6i2
Core Subject : Health, Science, Engineering,
Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Health Professions Medicine & Pharmacology
About the Journal IONTECH Journal is published by the Institute for Research and Community Service (LPPM), Institut Sains dan Teknologi Al-Kamal (ISTA). The journal publishes scientific articles in the fields of science, technology, and pharmacy contributed by leading academics and researchers in Indonesia. IONTECH is issued twice a year, in February and August. Open Access Policy IONTECH Journal applies a full open access policy. All articles are freely available to read, download, distribute, and cite without any charges. No Article Processing Charge (APC) is required from authors or readers. Focus and Scope IONTECH is committed to advancing Science, Technology, and Pharmacy, covering original research, literature reviews, and case reports. Science, Technology & Engineering Industrial, Mechanical, Electrical, Civil, Informatics, and Chemical Engineering Data Science & Statistics Biotechnology Device and Process Innovation Pharmacy Pharmacology & Toxicology Clinical & Community Pharmacy Pharmaceutical Chemistry & Biology Pharmaceutics & Biopharmaceutics Social Pharmacy, Management & Marketing Pharmacoepidemiology & Pharmacoeconomics Natural Products & Marine Pharmacy Alternative Medicines & Radiopharmacy Interdisciplinary Digital Health & IoMT Nanotechnology & Pharmaceutical Materials Bioinformatics & Big Data Artificial Intelligence (AI) & Blockchain Green Chemistry Tissue Engineering & Stem Cells Copyright The copyright of each article belongs to the authors and is licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) . Usage, distribution, and adaptation are permitted with proper attribution. Sponsorship This journal is fully funded and published by LPPM Institut Sains dan Teknologi Al-Kamal (ISTA). No external sponsors or advertisements are involved; editorial decisions remain independent. Publication History IONTECH was first published in Volume 1, Issue 1 (August 2020) as an initiative of LPPM ISTA to enhance national research dissemination in science, technology, health, and pharmacy. The journal has been continuously published twice a year — in February and August.
Arjuna Subject : -
Articles 75 Documents
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EVALUATION OF RATIONAL USE OF AMLODIPINE AND CAPTOPRIL IN TYPE 2 DIABETES MELLITUS PATIENTS WITH COMORBIDITIES AT TANGERANG DISTRICT GENERAL HOSPITAL Ahsan Yusma; Rizki Amalia Syafitri; Mutawalli Sjahid Latief; Febri Hidayat
IONTech Journal Vol. 6 No. 2 (2025): Agustus 2025
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v6i2.136

Abstract

Rational use of antihypertensive drugs is essential for patients with Type 2 Diabetes Mellitus (T2DM) with comorbidities to optimize therapeutic efficacy and minimize adverse drug reactions. This study aimed to evaluate the appropriateness of antihypertensive therapy in outpatient BPJS T2DM patients at RSU Tangerang District. A descriptive retrospective study was conducted on 80 BPJS T2DM patients with comorbidities who received captopril or amlodipine from January to June 2021. Data were collected from medical records and analyzed for appropriateness regarding contraindications, indications, drug selection, and dosage according to clinical guidelines including JNC VII/VIII, ACC/AHA, Pharmaceutical Care, and PIONAS. All patients received medications without contraindications, resulting in a 100% appropriateness rate. Specifically, 68.8% of patients received captopril and 31.3% received amlodipine appropriately. All indications and drug selections were fully aligned with clinical guidelines, and dosing was correct for all patients: captopril 12.5 mg in 14 cases (17.50%) and 25 mg in 41 cases (51.25%), amlodipine 5 mg in 19 cases (23.75%) and 10 mg in 6 cases (7.50%). Antihypertensive therapy in BPJS T2DM patients at RSU Tangerang District was rational and fully adherent to clinical guidelines, ensuring patient safety and therapeutic efficacy. The study was limited to two drugs and outpatient care; therefore, future research should include additional antihypertensive medications and care settings to generalize the findings.
PENGARUH MEDIA SOSIAL TERHADAP PEMASARAN PRODUK (UMKM) TOKO OBAT DI KUTAI TIMUR KALIMANTAN TIMUR Husnul Muamilah; Prabawati Ispatrinov
IONTech Journal Vol. 6 No. 2 (2025): Agustus 2025
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v6i2.137

Abstract

Pertumbuhan pesat platform digital telah mengubah cara Usaha Mikro, Kecil, dan Menengah (UMKM) mempromosikan serta memasarkan produk mereka. Di wilayah pedesaan dan berkembang, termasuk Kutai Timur, Kalimantan Timur, media sosial memainkan peran yang semakin penting dalam mendukung keberlanjutan dan daya saing bisnis. Penelitian ini bertujuan untuk menganalisis pengaruh media sosial terhadap strategi pemasaran dan kinerja UMKM di Kutai Timur, Kalimantan Timur. Pendekatan deskriptif kualitatif digunakan dengan melibatkan lima belas pelaku UMKM sebagai partisipan. Data dikumpulkan melalui wawancara langsung dan observasi lapangan. Peneliti melakukan wawancara terstruktur untuk memperoleh wawasan dari partisipan serta mengamati praktik pemasaran secara nyata. Hasil penelitian menunjukkan bahwa platform media sosial seperti Facebook, Instagram, dan WhatsApp berkontribusi signifikan terhadap keberhasilan kampanye pemasaran UMKM. Sebanyak dua belas UMKM memiliki toko fisik sekaligus memanfaatkan media sosial, sedangkan tiga UMKM sepenuhnya mengandalkan promosi daring karena tidak memiliki lokasi fisik. Media sosial terbukti efektif dalam menyebarkan informasi, memperoleh masukan pelanggan, serta menjalin hubungan dengan audiens sasaran dan pemangku kepentingan industri dengan biaya minimal. Pemasaran melalui media sosial meningkatkan daya saing UMKM dengan memperluas jangkauan pasar, memperkuat keterlibatan pelanggan, dan menekan biaya pemasaran, sehingga menjadi alat penting bagi pertumbuhan bisnis berkelanjutan di Kutai Timur.
EVALUASI KINERJA KEUANGAN APOTEK X BERDASARKAN RASIO NPM DAN BOPO SERTA IMPLIKASINYA TERHADAP EFISIENSI OPERASIONAL Imran Firman
IONTech Journal Vol. 6 No. 2 (2025): Agustus 2025
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v6i2.138

Abstract

Penelitian ini bertujuan untuk menganalisis kinerja keuangan Apotek X melalui pengukuran rasio profitabilitas Net Profit Margin (NPM) dan efisiensi operasional Biaya Operasional terhadap Pendapatan Operasional (BOPO) selama periode Januari–Desember 2024. Metode penelitian yang digunakan adalah deskriptif kuantitatif dengan memanfaatkan data sekunder berupa laporan keuangan bulanan, meliputi pendapatan operasional, laba bersih setelah pajak, serta total biaya operasional. Hasil penelitian menunjukkan bahwa nilai NPM Apotek X berada pada kisaran 2,1%–3,2% dengan rata-rata 2,65%, yang mencerminkan margin laba tipis namun konsisten. Sementara itu, nilai BOPO berfluktuasi antara 70%–95%, dengan pencapaian efisiensi terbaik pada Maret (70%) dan relatif stabil di bawah standar 90% pada sebagian besar bulan. Kondisi ini menunjukkan adanya hubungan erat antara efisiensi biaya dan profitabilitas, di mana penurunan BOPO diikuti oleh peningkatan NPM. Secara keseluruhan, Apotek X mampu menjaga stabilitas kinerja keuangan dengan tingkat efisiensi yang cukup baik. Namun demikian, strategi pengendalian biaya yang lebih konsisten serta upaya peningkatan pendapatan perlu dilakukan untuk mendorong profitabilitas yang lebih berkelanjutan di masa mendatang. Secara keseluruhan, Apotek X mampu menjaga stabilitas kinerja keuangan dengan tingkat efisiensi yang cukup baik. Namun demikian, hasil penelitian ini juga menegaskan bahwa profitabilitas sangat dipengaruhi oleh pengendalian biaya. Oleh karena itu, strategi efisiensi biaya yang lebih konsisten serta upaya peningkatan pendapatan perlu dilakukan untuk mendorong profitabilitas yang lebih berkelanjutan di masa mendatang.
PERANCANGAN SISTEM INFORMASI MANAJEMEN PENJUALAN MUHAMART SMK MUHAMMADIYAH 04 JAKARTA BARAT DENGAN METODE RAPID APPLICATION DEVELOPMENT Muhammad Prasteyo; Deden Hedin Purnama Binaefsa; Purwanto
IONTech Journal Vol. 7 No. 1 (2026): Februari 2026
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v7i1.151

Abstract

Muhamart SMK Muhammadiyah 04 Jakarta Barat is a school minimarket used as a learning facility while serving students’ needs such as food, beverages, and uniforms. The predominantly manual sales process leads to issues such as queues during break time, inefficient transaction and stock recording, and limited information for sales monitoring. This study aims to design and implement a web-based Sales Management Information System to support transaction monitoring, stock management, and sales/financial reporting. The system was developed using the Rapid Application Development (RAD) method through requirement planning, user design (prototyping), construction, and cutover phases. The system was modeled using Unified Modeling Language (UML) and implemented using Laravel (PHP), MySQL, and web technologies (HTML and CSS). Functional testing was conducted using black box testing. The results show that the system supports product data management, stock control, sales transactions, and structured reporting. User evaluation using a Likert scale produced an average score of 4.66 (strongly agree), indicating high acceptance and effectiveness in supporting Muhamart operations.
PERANCANGAN DAN IMPLEMENTASI SISTEM PENGELOLAAN DANA DONASI PADA YAYASAN KEMANGGISAN BERBASIS WEB DENGAN METODE WATERFALL Muhammad Rizki; Mundirin; Purwanto
IONTech Journal Vol. 7 No. 1 (2026): Februari 2026
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v7i1.157

Abstract

Donation fund management at Kemanggisan Foundation is still handled manually using Microsoft Excel, making it inefficient, error-prone, and difficult to access outside the foundation. In addition, donors must visit the foundation in person to donate, which is inconvenient. This study aims to design and implement a web-based donation fund management system to facilitate recording of income and expenses, generating financial reports, and enabling donors to donate online. The system was developed using the Waterfall model through requirement analysis, design, implementation, testing, and maintenance phases. The system was designed using UML, implemented using PHP and MySQL, and tested using Blackbox Testing. The results show that the system can manage income, expenses, and financial reports automatically. User evaluation using a Likert questionnaire involving 45 respondents achieved a satisfaction score of 85.44% (strongly agree category), indicating that the system improves efficiency, accuracy, and donor convenience.  
KAJIAN INTERAKSI ANTAROBAT DAN HUBUNGANNYA DENGAN POLIFARMASI PADA PASIEN SKIZOFRENIA Andi Ahriansyah; Mutawalli Sjahid latief
IONTech Journal Vol. 7 No. 1 (2026): Februari 2026
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v7i1.160

Abstract

Schizophrenia is a chronic mental disorder affecting thought processes, perception, affect, and behavior, requiring long-term pharmacotherapy. In routine practice, patients frequently receive multiple concurrent medications (polypharmacy) to control psychiatric symptoms and manage comorbid conditions, which may increase drug-related problems, particularly potential drug–drug interactions (pDDIs). This study aimed to identify pDDIs and examine their association with the number of prescribed drugs among outpatients with schizophrenia at a public hospital in Jakarta. A retrospective analytical cross-sectional study was conducted from January to June 2025. From 357 outpatients, 15 medical records met the inclusion criteria (age ≥18 years, schizophrenia as the primary diagnosis, complete demographic/clinical and medication data, and at least two drugs per visit). Patient characteristics and medication profiles were collected. pDDIs were identified based on drug combinations and categorized by severity. The association between the number of drugs (<3 vs ≥3) and pDDIs was assessed using chi-square testing with odds ratio (OR). Most patients were aged 46–55 years (53.3%), and 73.3% had no documented comorbidities. The most frequently prescribed antipsychotics were risperidone (46.7%) and clozapine (33.3%), and 66.7% of patients received ≥3 drugs. pDDIs were detected in all prescriptions (15/15; 100%), totaling 26 events, predominantly moderate (73.08%) rather than major (26.92%). The most common interaction was risperidone–trihexyphenidyl (15.38%). No statistically significant association was found between the number of drugs and pDDIs (p=0.591; OR 0.444; 95%CI 0.022–9.032). These findings highlight the need for ongoing medication review and clinical pharmacy services to mitigate interaction risks, particularly involving antipsychotics and concomitant therapies.
DRUG-RELATED PROBLEMS TERAPI ANTIDIABETIK PADA PASIEN DIABETES MELITUS TIPE 2 RAWAT JALAN: PROFIL KONTROL GLIKEMIK (HBA1C, GDP), KOMORBIDITAS DAN INTERAKSI OBAT Abdul Razak
IONTech Journal Vol. 7 No. 1 (2026): Februari 2026
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v7i1.161

Abstract

Type 2 diabetes mellitus (T2DM) is a chronic disease requiring long-term pharmacotherapy and is frequently accompanied by comorbidities, which may increase the risk of drug-related problems (DRPs), particularly in outpatient settings. This study aimed to describe the DRP profile related to antidiabetic therapy among T2DM outpatients during July–December 2025 and to review patient characteristics, medication patterns, glycemic control, and potential drug interactions. A retrospective cross-sectional descriptive study was conducted using purposive sampling based on completeness of medical records/prescriptions. The sample included 100 T2DM outpatients. Most patients were aged 46–55 years (56%) and female (61%), with hypertension (39%), neuropathy (20%), and CKD (17%) as the most common comorbidities. Antidiabetic monotherapy was used in 59% of patients and combination therapy in 41%; metformin was the most frequently used single agent (25%), while gliquidone + metformin was the most common combination (16%). Glycemic control was generally suboptimal, with HbA1c ≥9.0% in 59% and fasting plasma glucose >180 mg/dL in 47% of patients; the most common disease duration was 5–10 years (55%). A total of 29 DRP cases (29%) were identified, predominantly drug interactions (18%), followed by adverse drug reactions (5%), overdosing (4%), and underdosing (2%). The most frequent interactions involved antidiabetic agents with cardiovascular drugs, particularly insulin with beta-blockers and ACE inhibitors. In conclusion, DRPs were present among T2DM outpatients with drug interactions as the dominant category, highlighting the need for regular medication review, glucose monitoring, and patient education to improve therapy safety and effectiveness.  
HUBUNGAN KARAKTERISTIK PASIEN DAN PENGETAHUAN DENGAN KEPATUHAN MINUM OBAT ANTIHIPERTENSI: STUDI CROSS-SECTIONAL DI KLINIK PRATAMA Andi Ahsan Yusma; Imran Firman
IONTech Journal Vol. 7 No. 1 (2026): Februari 2026
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v7i1.163

Abstract

Hypertension is a chronic disease that requires long-term therapy; therefore, medication adherence is a key determinant of successful blood pressure control and may be influenced by patient characteristics and knowledge. This analytic observational cross-sectional study was conducted at a primary clinic in Makassar from May to July 2025 among 110 hypertensive outpatients (population: 152) selected using purposive sampling. Data were collected using questionnaires on patient characteristics, knowledge (10-item Guttman scale), and medication adherence (10-item modified ARMS-based 3-point scale); all items were valid (r-count > 0.30) and reliable (Cronbach’s alpha: knowledge 0.729; adherence 0.755). Most respondents were aged 46–55 years (39.1%), male (62.7%), had primary–secondary education (SD–SMA) (80.9%), and were employed (71.8%); high knowledge was found in 73.6% of respondents and high adherence in 79.1%. Knowledge level was significantly associated with medication adherence (p=0.002), and age (p=0.002), sex (p=0.001), education (p=0.001), and employment status (p=0.002) were also significantly associated with adherence, indicating the need for structured education and patient-tailored interventions to improve adherence and support successful antihypertensive therapy outcomes.
FORMULASI DAN EVALUASI SOLID PARFUMEDENGAN BASIS KARAGENANAN MENGGUNAKAN ESSENSIAL OIL CITRUS (Citrus sinensis), JASMINE (Jasminum sambac) DAN VANILA (Vanila planifolia) Iin Hardiyati; In Rahmi Fatria Fajar; Nia Novitasari
ISTA Online Technologi Journal Vol. 1 No. 1 (2020): Agustus 2020
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v1i1.22

Abstract

Abstrak Parfum merupakan produk yang tidak asing lagi digunakan dalam kehidupan sehari-hari sebagai suatu kebutuhan untuk tampil percaya diri. Parfum merupakan campuran senyawa aromatik, minyak essensial, fixatif, dan pelarut yang digunakan untuk memberikan keharuman dan dapat dikembangkan sebagi produk aplikasi minyak atsiri dalam bentuk solid parfum. Solid parfume adalah parfum padat yang umumnya terbuat dari campuran fume oil dan wax. Metode yang digunakan dalam penelitian ini yaitu metode eksperimental yang terdiri dari 6 tahapan diantaranya preformulasi, pemilihan bahan, pembuatan, hasil, evaluasi dan produk jadi. Penelitian ini bertujuan untuk membuat formulasi solid parfume dengan basis karagenanan dengan menggunakan essesial oil citrus, Jasmine dan vanila. Evaluasi yang dilakukan pada sediaan solid parfume dengan menggunakan beberapa metode diantaranya dengan uji hedonik, uji sensori, uji scoring, uji gravimetri dan uji stabilitas. Dan dari penelitian yang dilakukan dapat disimpulkan konsentrasi terbaik dari karagenanan sebagai basis adalah karagenanan 2,5% dan nilam 2% sebagai fixatif. Dari hasil tes uji hedonik essensial oil yang paling banyak disukai dari ketiga formula adalah formula dengan essensial oil citrus. Sedangkan solid parfume dengan vanila memiliki ketahanan wangi yang lebih awet dibandingkan dengan citrus dan jasmine. Dari hasil evaluasi stabilitas ketiga formula didapatkan hasil sediaan solid parfume yang stabil. Abstract Green perfume is a familiar product used in everyday life as a need to appear confident. Perfume is amixture of aromatic compounds, essential oils, fixatives, and solvents used to provide fragrance. Solidparfume is a solid perfume that is generally made of a mixture of fume oil and wax. The method usedin this study is an experimental method consisting of 6 stages including material selection,preformulation, manufacture, yield, evaluation and finished products. This research aims to makesolid perfume formulation with karagenanan base by using essesial oil citrus, Jasmine and vanilla. Theevaluation was performed on solid solid parfume by using several methods such as hedonic test,sensory test. scoring test, garvimetry test and stability test. And from research conducted can beconcluded the best concentration of carrageenan as base is carrageenan 2,5% and patchouli 2% as fixative. From the test results of the most preferred hedonic essential oil test of the three formulas is a formula with citrus oil essensial. While solid perfume with vanilla has a more durable fragrant resistance compared with citrus and jasmine. From the result of stability evaluation of the three formulas we get solid stable parfume dosage result.
UJI AKTIVITAS ANTIOKSIDANDAN PENETAPAN KADAR FLAVONOID TOTALDARI EKSTRAK ETANOL 70% DAUN KAPUK RANDU (CEIBA PENTANDRA(L.)GEARTN) DENGANMETODE DPPH Siva Fauziah; Nova Puspita Sari
ISTA Online Technologi Journal Vol. 1 No. 1 (2020): Agustus 2020
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v1i1.23

Abstract

Abstrak Daun kapuk randu mengandung senyawa flavonoid yang memiliki aktivitas sebagai antioksidan. Penelitian ini bertujuan untuk menetapkan kadar flavonoid totaldan menguji aktivitas antioksidan dari ekstrak etanol 70% daun kapuk randu (Ceiba pentandra (L.)Gaertn.) dengan menggunakan spektrofotometer UV-Vis. Penentuan kadar flavonoid total ekstrak etanol 70% daun kapuk randu (Ceiba pentandra (L.)Gaertn.) ditentukan berdasarkan nilai absorbansi yang diukur pada panjang gelombang sinar tampak 429,0 nm dengan menggunakan pembanding kuersetin. Uji akivitas antioksidan ekstrak etanol 70% daun kapuk randu (Ceiba pentandra (L.)Gaertn.) ini dilakukan dengan mengukur aktivitas peredaman ekstrak terhadap radikal DPPH (1,1-difenil-2-pikrilhidrazil) secara spektrofotometer UV-Vis pada panjang gelombang 515,0 nm. Hasil penelitian menunjukan kadar flavonoid total yang diperoleh pada ekstrak etanol 70% daun kapuk randu yaitu12,69%. Hasil dari uji aktivitas antioksidan ekstrak etanol 70% daun kapuk randu diperoleh nilai IC50 sebesar 59,296 ppm. Disimpulkan bahwa ekstrak etanol 70% daun kapuk randu memiliki potensi sebagai antioksidan yang kuat. Abstract Kapok leaves contain flavonoid compounds which have antioxidant activity. Research of determination of total flavonoid content and antioxidant activity of 70% ethanol extract in kapok leaf (Ceiba pentandra (L.)Gaertn.) by using UV-Vis spectrophotometer. Determination of total flavonoid levels of 70% ethanol extract kapok leaf (Ceiba pentandra (L.)Gaertn.) Extract was determined based on the absorbance value measured at the wavelength of visible light 429.0 nm using a comprator quercetin. Antioxidant activity test for ethanol 70% kapok leaf extract (Ceiba pentandra (L.)Gaertn.) was carried out by measuring the reducing activity of the extract against DPPH radical (1,1-diphenyl-2-picrylhydrazyl) by UV-Vis spectrophotometer at a wavelength of 515.0 nm. The results showed total flavonoid levels obtained on70% ethanol extract kapok leaf (Ceiba pentandra (L.)Gaertn.) is 12,69%. The results of the kapok leaf antioxidant activity test obtained IC50 values in 70% ethanol extract kapok leaf (Ceiba pentandra (L.)Gaertn.) is59,296 ppm. It was concluded that 70% ethanol extract kapok leaf (Ceiba pentandra (L.)Gaertn.) it has potential as a powerful antioxidant.

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