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Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
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Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 17 Documents
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Search results for , issue "Vol. 57, No. 3" : 17 Documents clear
The Effect of The Cucumber Consumption To The Level of Sodium Potassium in Mus Muscullus's Urine Production Elicia, Vincensa; Tjipto, Bambang Wasito; Novita, Bernadette Dian
Folia Medica Indonesiana Vol. 57, No. 3
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Cucumber (Cucumis sativus L.). was known for lowering blood pressure agents. Some researches show that Cucumber had a similar mechanism with a loop diuretic (Furosemide), exceeding sodium and potassium excretion. However, a part of Cucumber that gives a better effect on managing water and sodium balance remains unknown. This study was to explain the differences potential diuretic among parts of Cucumber (Cucumis sativus L.). This study was using a post-test only control group designed in animals. There were 44 male Mus musculus tested in this study. All of the animal testings was divided into 9 different treatment groups and 2 control groups. All Mus musculus got 1 mL methanol extract of Cucumber (Cucumis sativus L.) according to their group. The animal testing was put on metabolic cage to measure urine volume for 24 hours. The flesh and rind part of Cucumber (Cucumis sativus L.) showed a similar result with furosemide as diuretics agents. However, whole part of the fruit of Cucumber (Cucumis sativus L.) (flesh, rind, and seed) showed as natriuretic dan kaliuretic, Cucumber (Cucumis sativus L.) has a similar potential diuretic with Furosemide. Even in low concentrations of Cucumber extract, it led to having a potential diuretic, with natriuretic and kaliuretic effects in the whole part of the fruit. This could be suggested to people with chronic kidney diseases to prevent hyperkalemia.
Difference of Heat Shock Protein 70 Serum Level Between Primary Angle Closure Glaucoma and Open Angle Glaucoma Patients: Indonesia Single Center Experience Zuhri, Mohamad Nurdin; Nurwasis, Nurwasis; Retnowati, Endang; Purnomo, Windhu
Folia Medica Indonesiana Vol. 57, No. 3
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This study aimed to analyze the differences in Hsp 70 serum levels in patients with primary angle-closure compared to patients with open-angle glaucoma at Dr. Soetomo General Academic Hospital, Surabaya, East Java. This cross-sectional study was conducted on 41 subjects divided into 2 groups consisting of 21 patients with primary angle-closure glaucoma and 20 patients with open-angle glaucoma. Anterior segment examination was assessed by slit-lamp biomicroscope examination. Intraocular pressure on both eyes was measured by Perkin's tonometry. Posterior segment examination was performed with 78 D lens and anterior chamber angle was assessed by goniolens. The serum level of Hsp 70 was assessed using a human Hsp 70 sandwich ELISA kit. The data were statistically analyzed with the Mann-Whitney test. The mean serum levels of Hsp 70 in the primary angle-closure group was 5.55  4.75 ng/ml, while the open-angle group was 3.62  2.39 ng/ml (p = 0.134). There was no difference in Hsp 70 serum levels between the two groups, although the trend obtained serum levels of Hsp 70 patients with primary angle-closure was higher compared to patients with open-angle.
Effect of High Fat Diet on Body Weight, Visceral Fat Weight, and PPARG Expressions on Visceral Fat in Mice Melyana, Cantika Putri; Rejeki, Purwo Sri; Mudjanarko, Sony Wibisono; Herawati, Lilik; Al-Arif, Mohammad Anam
Folia Medica Indonesiana Vol. 57, No. 3
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Obesity becomes a global epidemic nowadays. The high-fat diet is used as an alternative therapy for obesity. The optimal composition of a high-fat diet to reduce body weight is still unknown. This study aimed to determine which components of a high-fat diet can decrease body weight, visceral fat, and PPARG expression of visceral fat. This study was conducted at the Faculty of Veterinary Medicine, Universitas Airlangga, for three months by using a randomized post-test only control group design. Fifty male mice, 2-3 months old, 18-30 grams were adapted for one week given standard diet AIN93-M, then mice were divided into five groups, namely K1 (control group, 12% fat, 20% protein, 62% carbs); K2 (30% fat, 60% proteins, 0% carbs); K3 (45% fat, 45% protein, 0% carbs); K4 (60% fat, 30% protein, 0% carbs); and K5 (75% fat, 15% protein, 0% carbs). Bodyweight was measured before and after treatment, then the visceral fat and PPARG expressions were evaluated. Statistical comparisons were performed using Statistical Package for the Social Sciences (SPSS) software. After treatment, there were forty-three mice. The body weight and visceral fat weight of the mice with a high-fat diet were decreased. The most significant changes in body weight were in K4 with -9,60 ± 3,806 grams reduction. The bodyweight of mice in K5, slightly increased than K2-K4. This could be caused by the hormesis phenomenon. PPARG expressions decreased in groups with a high-fat diet but increased in K5. The composition of a high-fat diet in group K4 was the most optimal to decrease the body weight, visceral fat, and PPARG expressions in mice
Evaluation of ANSI Z535 Safety Sign Installation Amaliyah, Mas; Widajati, Noeroel
Folia Medica Indonesiana Vol. 57, No. 3
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A safety sign is a sign of equipment to provide protection for workers or visitors in the workplace. American National Standards Institute Z535 (ANSI Z535) is used as a basic guideline for installing safety signs in the workplace because it is more communicative by using global symbols to overcome language barriers. Occupational Safety Division of Manpower and Transmigration Departement, East Java Province (UPT Keselamatan Kerja Surabaya) is a workplace that has a risk of occupational accidents. The preliminary surveys in the area of the 3rd floor of the Division of Occupational Safety (UPT Keselamatan Kerja) Surabaya revealed that there were many sites with insufficient safety signboards. Many of the installed safety signs did not comply with ANZI Z535 standards. This study aimed to evaluate the installation of safety signs compared to the ANZI Z535 standard on the 3rd floor of UPT K2 Surabaya. This was an observational study examining the installation of safety signs. The data were obtained using the ANSI Z535 safety sign checklist. We found 2 out of 5 types of safety signs were in accordance with ANSI safety sign standards with a comparison percentage of more than 66%, such as the notice sign (67.85%) and safety condition sign (75%). Three other types of safety signs were in the unfavorable category with a percentage of less than 66%, such as danger sign (65.63%), warning sign (50%), and caution sign (46.88%). Some sites required additional safety signs, such as warning signs (at distillation site), caution signs (oven, stairs), notice signs (cylinder storage, elevator, chemical warehouse), and safety condition signs (stair, eyewash).
Phylogenetic and Transmission Patterns of Extended-Spectrum β- Lactamase –Producing Escherichia Coli among Neonatal's Gut Flora in Indonesia Sulistya, Rakhmatul Binti; Kuntaman, Kuntaman; Koendhori, Eko Budi; Happy, Terza Aflika; Setyarini, Wahyu
Folia Medica Indonesiana Vol. 57, No. 3
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This study aimed to explore the phylogenetic pattern of Extended-spectrum β-lactamase-producing Escherichia coli in the gut flora of neonatal into groups A, B1, B2, D and tracing the presence of spreading among the age group of neonatal. Multiplex PCR was conducted to classify the phylogenetic group of ESBL producing E. coli into groups of commensals (A, B1) and pathogen (B2, D). The spread of bacterial agents among the host (neonatal) was conducted by the RAPD-PCR method with two random primers. Among 34 bacterial isolates were identified among early neonatal group A (22,2%), B1 (11,1%), B2 (22,2%) D (33,3%) and postneonatal groups A (8%), B1 (4%), B2 (36%) D (40%). It was not a statistically significant difference (p=0.388). The dominance of pathogenic groups B2 and D as many as 70,6%. From 34 samples was found 34 types of RAPD indicated there were not any bacterial spread among neonatal. The ESBL producing E. coli among early neonatal and postneonatal were dominated by the pathogenic group of B2 and D (total=70,6%), but they were not statistically significant. There was not any spreading of bacterial agents among individual gut flora of neonatal.
Skeletal-Related Events (SRE) in Prostate Cancer: A Report of Two Cases Diatmika, Anak Agung Ngurah Oka; Hardjowijoto, Sunaryo
Folia Medica Indonesiana Vol. 57, No. 3
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A skeletal-related event (SRE) is an event occurring due to bone metastasis in prostate cancer. SREs are usually marked by pain, pathological fractures, spinal cord compression, hypercalcemia, or bone metastasis requiring radiotherapy or operation. Case I: A 64-year-old male was diagnosed with a pathological fracture of the left femur. Thoracal CT scan showed osteoblastic lesions in the thoracal vertebrae, sternum, clavicle, and humeral head. Spinal MRI showed destruction of the cervical to sacral vertebral bodies. The histopathological result with Adenocarcinoma Gleason scores 8 (4+4) and an initial prostate-specific antigen (PSA) level of 689,7 ng/dL. Afterward, subcapsular orchiectomy was performed. However, his PSA level was still high (>100 ng/dL) even after serum testosterone had reached a castration level. The patient died during the first chemotherapy using docetaxel. Case II: A 61-year-old male was diagnosed with inferior paraplegia and neurogenic bladder, paraparesis, urinary retention, and pain in the flank area. Spinal MRI showed a pathological compression fracture of the 8th thoracic vertebrae. Thoracal CT scan showed costal and 8th thoracal vertebrae destruction as well as multiple nodules in the lungs. Histological results with Adenocarcinoma Gleason score 9 (4+5) and an initial PSA level of 750 ng/dL. Afterward, subcapsular orchiectomy was performed. Serum testosterone reached castration level with the lowest PSA concentration of 21.6 g/dL. The patient declined chemotherapy and agreed to palliative treatment. He died one year after diagnosis. A high PSA level (>500 ng/dL) could potentially be used as a predictor for severe SRE.
Back Matter Vol. 57 No. 3 September 2021 Matter, Back
Folia Medica Indonesiana Vol. 57, No. 3
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