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Contact Name
M. Irwan Hadi
Contact Email
office@yasin-alsys.org
Phone
+6285799379817
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office@yasin-alsys.org
Editorial Address
Jln Yasin No 01 Keruak, Kec. Keruak, Lombok Timur NTB
Location
Kab. lombok timur,
Nusa tenggara barat
INDONESIA
African Journal of Biochemistry and Molecular Biology Research
Published by Lembaga Yasin Alsys
ISSN : -     EISSN : 15957926     DOI : https://doi.org/10.58578/AJBMBR
Core Subject : Science,
African Journal of Biochemistry and Molecular Biology Research aims to publish high-quality, peer-reviewed research that advances biochemical and molecular understanding of living systems while supporting interdisciplinary developments across the life sciences. • Biochemical Advancement: disseminate rigorous studies in fundamental and applied biochemistry, including molecular mechanisms, metabolism, enzymes, membranes, and biomolecular interactions. • Molecular and Cellular Inquiry: encourage research in molecular biology, genetic and cellular regulation, pathogen biology, and biologically relevant analytical methods. • Life-Science Integration: promote interdisciplinary work linking biochemistry and molecular biology with biotechnology, physiology, microbiology, pharmacology, pathology, and health science. • Scientific Relevance and Application: support research that contributes to biomedical, environmental, agricultural, nutritional, and translational scientific problems. AJBMBR welcomes original research papers and related scholarly contributions in biochemistry, molecular biology, and associated life-science fields, especially studies with strong methodological grounding and clear scientific relevance. • Core Biochemistry: macromolecular biochemistry, enzymology, membrane biochemistry, nutritional biochemistry, reproductive and developmental biochemistry, and biochemical regulation of cellular processes. • Molecular and Biomedical Sciences: molecular biology, medical and clinical biochemistry, pathology, pharmacology, physiology, microbiology, parasitology, malariology, and related disease-oriented biosciences. • Biotechnology and Bioinformatics: biotechnology, computational biology, bioinformatics, molecular data analysis, and applied laboratory innovation. • Health and Natural Product Sciences: phytomedicine, food science, health science, toxicology, and biophysics relevant to biomolecular or physiological understanding. • Environmental and Applied Biosciences: environmental biochemistry and other biochemical applications connected to biological systems, sustainability, and applied life-science research.
Articles 101 Documents
Unlocking the Potential of Carica papaya L.: A Comprehensive Review on Its Antiviral Activity and Therapeutic Role in Dengue Management Dluya Samuel Thagriki
African Journal of Biochemistry and Molecular Biology Research Vol 3 No 3 (2026): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v3i3.11641

Abstract

Dengue is a rapidly expanding global health problem for which no specific antiviral therapy is currently available, leaving disease management largely supportive and symptomatic. Severe thrombocytopenia is a major clinical concern in dengue infection, while prophylactic platelet transfusion can be costly and may not always be readily accessible. Carica papaya leaf juice (CPLJ) has been used off-label in the management of dengue fever and dengue haemorrhagic fever and has been reported to increase platelet counts in thrombocytopenic children and adults with minimal adverse effects. This review synthesizes evidence on the antiviral activity and therapeutic potential of CPLJ and C. papaya leaf extracts in the treatment and recovery of dengue-infected patients. It examines recent findings from in vitro and in vivo studies, documented clinical trials, traditional applications, and research on the phytochemicals, amino acids, and other bioactive constituents of C. papaya leaves. The reviewed evidence indicates that CPLJ and its extracts may inhibit dengue virus activity, increase platelet counts, and support recovery among patients with dengue fever and dengue haemorrhagic fever. These findings suggest that C. papaya leaves represent a promising natural source of bioactive compounds for developing supportive or antiviral interventions against dengue virus infection. Nevertheless, further rigorous pharmacological and clinical investigations are required to establish standardized formulations, therapeutic dosages, mechanisms of action, safety profiles, and clinical efficacy.

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