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Journal of Health Science and Pharmacy
Published by Yayasan Cipta Anak Bangsa (YCAB) Publisher
ISSN : -     EISSN : 30906148     DOI : https://doi.org/10.36685/jhsp
Core Subject : Health, Social,
Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health
Journal of Health Science and Pharmacy adalah jurnal ilmiah yang ditinjau oleh rekan sejawat, yang berfokus pada publikasi penelitian berkualitas tinggi di bidang ilmu kesehatan dan farmasi. Jurnal ini menyediakan platform bagi akademisi, peneliti, dan profesional kesehatan untuk berbagi temuan penelitian terbaru, inovasi klinis, dan kemajuan teknologi di bidang terkait kesehatan. Cakupan jurnal meliputi farmakologi, farmakokinetik, formulasi obat, manajemen farmasi, kesehatan masyarakat, epidemiologi, kesehatan lingkungan, kesehatan dan keselamatan kerja, promosi kesehatan, nutrisi klinis, kedokteran preventif, dan kebijakan kesehatan. Jurnal Ilmu Kesehatan dan Farmasi menerbitkan artikel penelitian asli, tinjauan sistematis, laporan kasus, dan komunikasi singkat yang memberikan kontribusi signifikan terhadap perkembangan ilmu kesehatan. Dengan standar editorial yang ketat dan proses peninjauan rekan sejawat yang komprehensif, jurnal ini berkomitmen untuk menerbitkan penelitian berbasis bukti yang dapat diterapkan dalam praktik klinis dan memiliki dampak positif pada peningkatan kualitas layanan kesehatan dan pengembangan strategi pengobatan yang lebih efektif dan aman di Indonesia dan global.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 92 Documents
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Cases of Pulmonary Tuberculosis Based on Nutritional Status of Ponorogo Regency in 2016-2020 Nurfatin Tria; Nur Fatin; Rahma Samsir; Nur Faizah; Opy Linda; Nurfita Sari
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1533

Abstract

Background: The screening rate for suspected pulmonary tuberculosis cases, facilitated through health promotion activities in collaboration with the Ponorogo District Health Office, serves as a key indicator of the effectiveness of our efforts in controlling the disease. Objective: To analyze the predictive relationship between nutritional status and the incidence of pulmonary tuberculosis in Ponorogo Regency. Method: This study employed a descriptive research design to analyze a specific population at a single point in time. The sample and population consisted of nutritional status data of individuals with pulmonary tuberculosis whose sputum test results were positive in Ponorogo Regency. Results: The incidence of pulmonary tuberculosis in Ponorogo Regency increased from 276 cases in 2011 to 392 cases in 2012, followed by 378 cases in 2013. The number then decreased to 293 in 2014 and increased again to 334 in 2015. The projected decrease in cases was 299 for 2016 and 306 for 2020. The time series analysis revealed a decrease in pulmonary tuberculosis cases with positive sputum test results, which correlated with nutritional conditions. Conclusions: The application of a quadratic trend model for time series analysis demonstrated that the incidence of pulmonary tuberculosis was influenced by nutritional status, including factors such as obesity, overnutrition, normal nutrition, and malnutrition. Keywords: Pulmonary tuberculosis, nutritional status, time series analysis, health promotion, Ponorogo Regency
Analysis of The Prevalence of Stunting Rates in Provinsi Jawa Barat, Bandung Devi Savitri Effendy; Nur Azizah Rianty Gamoro; Nayla Azizah; Rencong Pandelaki
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1534

Abstract

Background: Stunting is a chronic growth disorder in children under five, defined as a height-for-age z-score below minus two standard deviations from the WHO Child Growth Standards median. Southeast Asia has one of the highest stunting burdens globally, and Indonesia remains among the countries with a high prevalence. Within West Java Province, Bandung Regency was reported as one of the districts with the fifth-highest stunting prevalence in 2022. Objectives: This study aims to describe the trend of stunting prevalence in West Java Province, with a particular focus on Bandung City, during the period 2018–2022. Methods: This study applied a quantitative descriptive approach to characterize stunting prevalence trends in West Java Province, with a specific focus on Bandung City. Secondary data were obtained from the Indonesian Nutrition Status Survey (SSGI) for West Java Province published by the Ministry of Health of the Republic of Indonesia. The analysis used stunting prevalence estimates from 2018 to 2022 and summarized temporal patterns across the observation period. Results: The trend analysis indicated that stunting prevalence in Bandung City declined in 2019 to 27.1% but increased sharply in 2020 to 35%. These fluctuations suggest that stunting is not solely a nutritional problem but a multidimensional condition shaped by interrelated determinants. Key contributing factors include inadequate dietary intake, maternal and child health status, household socioeconomic constraints, and an unsupportive living environment. Limited access to health services, safe water, and adequate sanitation further exacerbates the risk of impaired linear growth. Conclusion: Stunting represents a complex public health issue reflecting nutritional, social, economic, and environmental vulnerabilities. In Bandung City, prevalence decreased in 2019 but rose again in 2020 and remained above the WHO threshold in 2022, underscoring the need for integrated and sustained interventions. Keywords: stunting; prevalence; West Java; Bandung City; SSGI.
Overview of Dengue Fever (DHF) Cases in East Java Province in 2022 - 2023 Ramadhan Tosepu; Nirin Raudhatul Janna; Norma Ilham Siddik; Nurul Aina Jamil; Nisa Al Jannah Harsit; Pramudya Wira Ananta
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1535

Abstract

Background: Dengue hemorrhagic fever (DHF) remains an endemic vector-borne disease in Indonesia, characterized by substantial annual fluctuations and recurrent outbreaks, particularly during the rainy season. East Java Province continues to contribute a considerable burden of reported DHF cases, underscoring the need for epidemiological profiling to support targeted control efforts. Objective: This study aimed to describe the temporal and spatial distribution of DHF cases in East Java Province during 2018–2020 and to summarize case patterns according to selected demographic and contextual indicators. Methods: A quantitative descriptive study with a time-series approach was conducted using secondary data. DHF case data were obtained from the East Java Provincial Health Profile (2018–2020). Climate variables (air temperature, relative humidity, rainfall, and sunshine duration) and population density data were retrieved from the Central Statistics Agency for the same period. Data were analyzed descriptively to assess year-to-year changes and distributions by time and district/city, and stratified by sex where available. Results: The number of DHF cases in East Java showed an overall increase from 2018 to 2020, although the pattern was unstable across years and varied substantially between districts/cities. Higher case concentrations were observed in several areas, reflecting heterogeneous transmission dynamics potentially associated with population density and seasonal climatic conditions. Conclusion: DHF burden in East Java increased during 2018–2020 with pronounced spatiotemporal variation. These findings support strengthening routine surveillance, climate-informed early warning, and community-based vector control to enhance prevention and response. Keywords: dengue hemorrhagic fever; East Java; climate; population density; time series
Trends in Dengue Fever Incidence in Tomohon City, North Sulawesi, Indonesia, 2021-2023 Fakhrul Mubarak Ahmad; Ihsan Adi Sasono; Hamdawang
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1543

Abstract

Background: Maternal and child health are essential indicators for evaluating the health status of a population and assessing the effectiveness of health sector development. West Sulawesi Province, located in Eastern Indonesia, faces significant challenges in reducing maternal and infant mortality rates. Factors such as geographical accessibility, the availability of healthcare personnel, and various social determinants contribute to the distribution of maternal and neonatal mortality in this region. Objectives: This study aims to describe the distribution of maternal and infant mortality in West Sulawesi Province from 2017 to 2020, using secondary data obtained from the West Sulawesi Provincial Health Profile. Methods: A descriptive quantitative approach was employed in this study, analyzing secondary data sourced from the Health Profile of West Sulawesi Province. The data include the annual number of maternal and infant deaths, which were organized into tables and graphs for analysis. The trends and patterns observed were interpreted narratively to provide a comprehensive overview of the data. Results: Based on Chart 1, the highest trend in dengue fever cases occurred in 2018, with 115 reported cases. This increase may be attributed to several factors, including high rainfall, population density, and local behaviors. Conclusion: Dengue Hemorrhagic Fever (DHF) poses a significant health threat, as it can develop into a deadly epidemic. Recognizing the trends and factors influencing DHF incidence is crucial for implementing effective early prevention strategies. Environmental factors, such as high rainfall, along with population density and behavioral patterns, contribute to the high incidence of DHF in certain areas. Keywords: Dengue Hemorrhagic Fever, Dengue Virus, Aedes Aegypti, Trends, Indonesia
Formulation of Dragon Fruit Skin Nail Polish Cosmetic Preparations (Hylocereus Polyrhizus) Dinasti; Sri Yolandari; Sitti Alfyanita Ilham
Journal of Health Science and Pharmacy Vol. 2 No. 3 (2025): September - December
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v2i3.1550

Abstract

Background: Dragon fruit (Hylocereus polyrhizus) is widely recognized for its nutritional value and health benefits. However, its peel is often discarded as waste, despite containing high levels of anthocyanins. These natural pigments are responsible for the red coloration of dragon fruit and have considerable potential as safe, environmentally friendly alternatives to synthetic dyes, particularly in cosmetic applications. Objectives: This study aims to evaluate the feasibility of utilizing dragon fruit peel extract as a natural dye in nail polish formulations and to assess the physical characteristics of the resulting cosmetic products. Methods: An experimental laboratory-based study was conducted by formulating nail polish using dragon fruit peel extract at three different concentrations: 8% (F1), 9% (F2), and 10% (F3). The formulated products were evaluated through organoleptic testing to assess physical appearance attributes, including color, form, and aroma. Panelist preferences were recorded to determine the most acceptable formulation. Results: The findings demonstrate that dragon fruit peel extract can be successfully used as a natural coloring agent in nail polish formulations. Among the three formulations, F3 (10% extract concentration) was identified as the most preferred, with 8 out of 10 panelists selecting it as the best formulation. This formulation exhibited the most attractive color intensity and the most favorable physical characteristics. Conclusion: Dragon fruit peel extract shows strong potential as a natural dye in cosmetic products, particularly nail polish. The use of a 10% extract concentration produced the most acceptable formulation, supporting the utilization of agricultural waste as a sustainable and safe alternative to synthetic cosmetic dyes.  
Preparation Formulationlip Creamhenry Leaf Extract (Lawsonia Inermisl) As A Natural Dye Febi Arsita Safitri; Evi Mustiqawati; Restu Harisma Damayanti
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1559

Abstract

Background: Indonesia possesses abundant plant resources with significant potential for use as natural ingredients in cosmetic products, one of which is henna leaves (Lawsonia inermis L.). Henna leaves contain natural orange pigments that can be utilized as colorants. The distinctive orange hue of henna makes it a promising natural dye for decorative cosmetic products, particularly lip cream formulations, as an alternative to synthetic dyes. Objectives: This study aimed to formulate a lip cream preparation using henna leaf extract as a natural colorant and to evaluate the physical properties of the resulting formulations. Methods: Henna leaf extract was obtained through the maceration method using 70% ethanol as the solvent. The extract was then formulated into lip cream preparations with three different concentrations: F1 (2%), F2 (4%), and F3 (6%). Physical evaluation of the lip cream included organoleptic assessment, homogeneity test, spreadability test, and pH measurement. Results: The organoleptic evaluation showed that all formulations produced a brown-colored lip cream with a semi-solid consistency. Homogeneity testing indicated that all formulations were homogeneous. The pH values of F1, F2, and F3 were within the acceptable range for lip cream preparations. However, the spreadability test results revealed that none of the formulations met the specified requirements. Conclusion: Henna leaf extract demonstrates potential as a natural colorant in lip cream formulations. Nevertheless, further formulation development is required to improve the spreadability characteristics to achieve optimal physical quality of the product. Keywords: Henna Leaves, Formulation, Lip Cream, Natural Colorant
Pharmaceutical Service Standards In Pharmacies In Baubau City Hasna Rahmawati; Hasty Hamzah; Sitti Alfyanita Ilham
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1560

Abstract

Background: Pharmaceutical services play a critical role in safeguarding public health by ensuring the rational, safe, and effective use of medicines. In Indonesia, the implementation of pharmacy service standards is regulated through the Decree of the Minister of Health of the Republic of Indonesia Number 73 of 2016, which serves as a framework to improve the quality and consistency of pharmaceutical services in community pharmacies. Objectives: This study aimed to assess the extent of compliance with pharmaceutical service standards in community pharmacies in Baubau City. Methods: A descriptive cross-sectional survey with a quantitative approach was conducted in 19 community pharmacies in Baubau City. Data were collected using a structured questionnaire derived from the pharmaceutical service standards stipulated in Minister of Health Decree No. 73/2016. Descriptive statistics were applied to summarize findings in the form of frequencies and percentages across key assessment domains, including human resources, facilities and infrastructure, and service quality. Results: The evaluation indicated that most pharmacies demonstrated adequate implementation of pharmaceutical service standards. Overall, 74% of pharmacies were categorized as “good,” while 26% were classified as “fair/adequate,” based on aggregated performance across the assessed domains. Conclusion: The majority of community pharmacies in Baubau City have implemented pharmaceutical service standards in accordance with Minister of Health Decree No. 73/2016 at a generally good level. However, a proportion of pharmacies still show only adequate compliance, highlighting the need for continuous supervision, capacity building, and quality improvement initiatives to strengthen pharmaceutical service delivery. Keywords: pharmaceutical services; community pharmacy; service standards; cross-sectional survey; Baubau City
Formulation and Physical Stability Test of Body Scrub Cream with Mangosteen Peel Extract (Garcinia Mangostana L) Yumiyati; Ratih Nurwanti; Sarni
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1563

Abstract

Background: Mangosteen (Garcinia mangostana L.) is a plant known for its various beneficial properties, particularly in its thick skin, which contains xanthone compounds. These compounds have antioxidant properties that are beneficial for the skin. The use of mangosteen skin extract as a key ingredient in body scrub creams has gained attention due to its potential skin benefits. Objectives: This study aimed to develop a body scrub cream formulation using mangosteen skin extract (Garcinia mangostana L.), assess the physical stability of the cream, and determine the most optimal formulation for its preparation. Methods: This study employed a laboratory experimental design, utilizing a maceration extraction method with 96% ethanol as the solvent to extract mangosteen skin compounds. Three different body scrub cream formulations were prepared with varying concentrations of mangosteen skin extract: Formula 1 (5%), Formula 2 (10%), and Formula 3 (15%). The physical stability and effectiveness of each formulation were tested through organoleptic evaluation, homogeneity, pH, adhesion, spreadability, and cream stability tests. Results: All three body scrub cream formulas were successfully formulated with mangosteen skin extract. However, none of the formulations met the optimal criteria. While all formulas passed the physical stability tests, including organoleptic evaluation, homogeneity, pH, adhesion, and cream consistency, none of the formulas passed the spreadability test. Conclusion: Although the body scrub creams demonstrated acceptable physical characteristics, the spreadability aspect requires further improvement to meet the expected standards for an optimal product. The results indicate the potential of mangosteen skin extract in body scrub formulations, but refinements are necessary to enhance the overall quality. Keywords: Body Scrub Cream, Mangosteen Peel, Phycal Stability Test
Assessment of the Analgesic Effect of Ethanol Extract of Red Lemongrass Leaves (Cymbopogon nardus) Using a Mouse Model (Mus musculus) Findi Prasetia; Muhammad Tasjiddin Teheni; Sarni
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1564

Abstract

Background: Public interest in plant-based traditional medicines continues to increase, encouraging scientific evaluation of commonly used herbal materials, including red lemongrass (Cymbopogon nardus) leaves, which are presumed to possess analgesic properties. Objectives: This study aimed to evaluate the analgesic effectiveness of the ethanol extract of red lemongrass leaves (Cymbopogon nardus) in mice (Mus musculus). Methods: An in vivo experimental design was employed using mice as the test model. Analgesic activity was assessed by quantifying the number of writhing responses (wriggles) following pain induction. The extract was administered in three dose groups, and the data were analyzed using one-way ANOVA to determine differences among groups. Results: The ethanol extract of red lemongrass leaves demonstrated analgesic activity in mice, indicated by a reduction in writhing responses. The highest analgesic effect was observed at a dose of 800 mg/kg body weight, suggesting a dose-dependent relationship in which higher extract doses produced greater analgesic activity. One-way ANOVA showed a significant difference among the extract-treated groups (F = 2.434 > Fcrit = 2.067), leading to rejection of the null hypothesis and confirming statistically significant variation across doses. Conclusion: Ethanol extract of red lemongrass leaves (Cymbopogon nardus) exhibits analgesic effects in mice (Mus musculus), with the most effective dose in this study being 800 mg/kg body weight. The findings support a dose-dependent analgesic response and indicate the potential of C. nardus as a candidate for further analgesic development. Keywords: Cymbopogon nardus; ethanol extract; analgesic activity; writhing test; Mus musculus
Effectiveness of Drug Booklet Administration on Hypertensive Patients' Compliance Levels at the Central Hospital of Buton Regency Adriani; Muhammad Tasjiddin Teheni; Sitti Alfyanita Ilham
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1565

Abstract

Background: Hypertension is defined by a systolic blood pressure of 140 mmHg or higher and a diastolic blood pressure of 90 mmHg or higher. This condition is associated with an increased risk of damage to vital organs, including the heart and the brain, potentially leading to cerebrovascular accidents. Medication adherence is crucial for managing hypertension and preventing complications. Objectives: The aim of this study was to evaluate the effect of educational booklet media on medication adherence among hypertensive patients receiving treatment at the Central Buton Regional General Hospital. Methods: This study employed a one-group pre-and post-test design using a pre-experimental method. The research focused on hypertensive patients and utilized the Morisky Medication Adherence Scale (MMAS-8) questionnaire to measure medication adherence. Qualitative research methods were applied to assess the impact of the educational booklet on patient behavior. Results: The results indicated that the provision of medication instructions through educational booklets significantly influenced the adherence of hypertensive patients at the Central Buton Regional General Hospital. Prior to receiving the educational booklet, 5 respondents (7.7%) demonstrated high adherence, 12 respondents (18.5%) showed moderate adherence, and 48 respondents (73.8%) exhibited low adherence. After the intervention, 8 respondents (12.3%) exhibited high adherence, 21 respondents (32.3%) displayed moderate adherence, and 36 respondents (55.4%) had low adherence. Conclusion: The distribution of the educational booklet at the Central Buton Regional General Hospital had a positive impact on hypertensive patients' medication adherence. While there was an improvement in adherence levels, the majority of patients still exhibited low adherence after the intervention. This suggests that while educational materials are beneficial, additional strategies may be necessary to further improve adherence and control blood pressure. Keywords: Medicine Booklet, Central Buton, Hypertension, Compliance; Drug Booklet

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