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Nadya Syarifatul Fajriyah
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Department of Biomedical Science, Faculty of Medicine, Universitas Muhammadiyah Metro, Jl. Gatot Subroto No. 100, Yosodadi, Metro Timur, Kota Metro, Lampung 34112, Indonesia.
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Jurnal Sains Biomedis
Published by Universitas Muhammadiyah Metro
ISSN : 31096743     EISSN : 31098045     DOI : https://doi.org/10.24127/biomedis.v1i02.10545
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Jurnal Sains Biomedis is a journal that aims to publish articles dedicated to the development education biology, Bioedukasi journal receiving and publishing article in the form of research (scientific article) in the, the study of literature, ideas, application of theory, critical analysis study, in the field of Biology Special emphasize are as follow: Health (Public Health, Health Analytics, Pharmacy) Biological sciences (biology, chemistry, microbiology, pharmacy, biotechnology, molecular cell biology) Medical
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Articles 10 Documents
 1 
Rasionalitas Masyarakat dalam Swamedikasi Vitamin C selama Pandemi Covid-19 Febrial Hikmah
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8502

Abstract

Background: Self-medication, both with herbs and chemical supplements, is people’s choice in dealing with the COVID-19 pandemic. Vitamin C is the most widely consumed supplement by the public on a self-medicated basis during the pandemic. Consumption of vitamin C as daily consumption must be an important concern of the community so that it becomes beneficial for the body. The aim of the study: This research was conducted to rationality of society in self-medication of vitamin C during the COVID-19 pandemic. Research method: This research is a descriptive study using a cross-sectional design. This research was conducted using a community self-medication rationality questionnaire for vitamin C, including the right indication, the right storage, the right dose, the right way of giving, the right time of administration and being aware of side effects. Result: Based on the 289 respondents in this study, it was illustrated that 90.3% of the respondents consumed vitamin C to increase their immune system and 67.1% of the respondents consumed vitamin C not only when they were sick. 76.1% of respondents knew the dose before consuming vitamin C, 86.5% of respondents consumed vitamin C <1000 mg/day, and 50.2% of respondents consumed vitamin C ≥1000 mg/week. As many as 88.2% of respondents consumed vitamin C after eating and 85.1% of respondents read the rules of consumption. As many as 68.9% of respondents read the side effects on the packaging, 85.8% of respondents did not experience side effects after consuming vitamin C, and 91.3% of respondents did not experience gastric irritation after consuming vitamin C. As many as 87.2% of respondents stored vitamin C at room temperature and 93.8% of respondents stored in a closed container. Conclusions: Public rationality in self-medication with vitamin C during the COVID-19 pandemic is a good category (82%).
Potensi Repellent Ekstrak Kulit Jeruk Lemon (Citrus limon Linn.) terhadap Nyamuk Aedes sp. Suharno Zen; Nadya Syarifatul Fajriyah; Ilham Fathurrahman; Miftahuz Zakiyah
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8849

Abstract

Jeruk lemon (Citrus limon Linn.) merupakan tanaman dengan jenis kulit yang memiliki kandungan senyawa fitokimia yaitu flavonoid, terpenoid, tanin dan limonen yang dapat dimanfaatkan sebagai insektisida nabati. Kandungan senyawa kimia tersebut memiliki kemampuan untuk mortalitas nyamuk, dan berperan sebagai racun pernapasan serta racun perut bagi nyamuk tersebut. Tujuan penelitian ini yaitu untuk mengetahui pengaruh dari ekstrak kulit jeruk lemon (Citrus limon Linn.) terhadap mortalitas nyamuk Aedes sp., serta mengetahui potensinya sebagai repellent. Jenis penelitian yang digunakan dalam penelitian ini adalah eksperimen dengan menggunakan rancangan penelitian berupa Rancangan Acak Lengkap (RAL) yang dilakukan dengan menggunakan 3 perlakuan variasi dosis ekstrak kulit jeruk lemon (Citrus limon Linn.) yaitu 25%, 27,5%, dan 30% serta kontrol (+) dan (-). Pengumpulan data dilakukan dengan melihat dan mencatat mortalitas/kematian dari nyamuk Aedes sp. setelah diberikan perlakuan dan mengamati nyamuk yang hinggap pada tubuh mencit dan menghitung jumlah nyamuk yang hinggap menggunakan rumus Daya Proteksi. Data diuji statistik menggunakan Anava Satu Jalur dan dilanjutkan dengan uji BNT (Beda Nyata Terkecil). Hasil penelitian diperoleh nilai Fhitung˃Ftabel yaitu 0,484 pada taraf α=0,05 sehingga H0 ditolak dan H1 diterima. Artinya terdapat pengaruh yang signifikan dari masing-masing perlakuan. Dosis terbaik yang efektif yaitu dosis 30% dengan jumlah nyamuk mati sebanyak 50 ekor. Daya proteksi tertinggi pada konsentrasi 30% sebesar 97,3%, sedangkan daya proteksi terendah pada konsentrasi 25% sebesar 77,1%.
Vegetasi Pantai sebagai Apotek Alam: Keragaman Spermatophyta Berkhasiat Obat dan Peluang Pemanfaatannya Suharno Zen; Rinta Aprilia; Miftahuz Zakiyah; Nadya Syarifatul Fajriyah; Ilham Fathurrahman
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8940

Abstract

One of the plant groups that dominate coastal vegetation is Spermatophyta, which not only has an ecological function as a coastal protector and erosion prevention, but also has great potential as a medicinal plant. This study aims to explore the diversity and potential of coastal vegetation plants as a source of natural medicine that can be used for traditional and modern medicine. In this study, identification of the types of plants that grow along the coast was carried out. The method used includes collecting plant samples, This type of research is descriptive. The method used is purposive sampling with the line transect technique. Determination of 3 locations as sampling stations at Tanjung Setia Krui Beach, West Lampung. Furthermore, the results of the inventory were identified using the Spermatophyta identification book. The research results found 11 plant species that have the potential as natural medicinal plants, namely kelapa (Cocos sp), sea pandan (Pandanus tectorius), ketapang (Terminalia catappa), tapak liman (Elephantopus scaber), beluntas (Pluchea indica), babandotan/bandotan (Ageratum conyzoides), waru (Hibiscus tiliaceus), krokot (Portulaca oleracea), ornamental beans (Arachis pintoi), butun or keben (Barringtonia asiatica) and katang (Ipomea pes-caprae). The Diversity Index (H’) of higher plants that make up coastal vegetation at Tanjung Setia Krui Beach is 1.061. So it is categorized as moderate, the Dominance Index (ID) of station 1 is 0.112, station 2 is 0.108, station 3 is 0.358. So it is categorized as low. This study provides knowledge about the potential for utilizing coastal vegetation plants as sustainable natural resources, the development of natural medicinal products, especially in the use of natural materials as an alternative treatment.
Potensi Air Liur Nyamuk sebagai Biomarker Diagnosis Infeksi Dengue Suharno Zen; Nadya Syarifatul Fajriyah; Ilham Fathurrahman; Miftahuz Zakiyah
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8941

Abstract

Dengue Hemorrhagic Fever (DHF) is a disease caused by the dengue virus and transmitted through the bite of the Aedes aegypti mosquito. Early diagnosis is essential to reduce the severity and mortality rate of this infection. Recent studies have shown that mosquito saliva contains specific biomarkers that can be used to detect dengue infection non-invasively. This study uses a systematic literature review method, namely tracing and analyzing various scientific publications relevant to the topic of non-invasive diagnostics for dengue. The results of the study can be concluded that: that mosquito saliva has great potential as a source of biomarkers for non-invasive dengue diagnosis. This method can be a more effective and easily accessible solution, especially in dengue endemic areas. However, to increase its effectiveness, further research is needed in the aspects of developing biomarker-based diagnostic kits, validation in various epidemiological environments, integration of this method in the global health system and regulation of policy makers
Kajian Senyawa Aktif Tanaman Obat sebagai Agen Antihipertensi pada Kehamilan Nadya Syarifatul Fajriyah; Suharno Zen; Ilham Fathurrahman; Miftahuz Zakiyah
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8949

Abstract

Hypertension during pregnancy is a major complication that poses significant risks to both maternal and fetal health. While pharmacological treatments are commonly used, their application is often limited due to potential adverse effects on fetal development, thereby necessitating safer alternative therapies, such as the use of medicinal plants. This study aims to examine the active compounds found in medicinal plants with antihypertensive potential and to evaluate their mechanisms of action within the context of pregnancy. A descriptive qualitative literature review was conducted by analyzing scientific articles published between 2010 and 2025 through databases such as PubMed, ScienceDirect, and Google Scholar. The review identified several plants, including Moringa oleifera, Zingiber officinale, Annona muricata, and Cymbopogon citratus, which contain bioactive compounds such as flavonoids, gingerol, acetogenins, and citral. These compounds contribute to blood pressure reduction through mechanisms such as vasodilation, antioxidant activity, diuretic effects, and inhibition of the angiotensin-converting enzyme (ACE). The findings suggest that these active compounds from medicinal plants have promising potential as safe antihypertensive agents during pregnancy; however, further large-scale clinical trials are necessary to confirm their long-term safety and efficacy
Transformasi Biomedik Menuju Personalisasi dan Kesehatan Presisi pada Kanker Niken Rahmah Ghanny; Herera Rahajeng; Pararawendy Indarjo; Afifa Radhina; Muhammad Fadhil
Jurnal Sains Biomedis Vol. 1 No. 02 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i02.10545

Abstract

Biomedical transformation is redefining cancer research and clinical practice by integrating experimental and computational approaches, digital technologies, and patient-specific models to realize precision health. Wet lab experiments generate molecular, imaging, and clinical data, while computational biology and artificial intelligence (AI) interpret complex datasets to uncover predictive biomarkers, optimize therapy selection, and simulate tumor behavior. Digital transformation accelerates data integration through multi-omics, radiomics, and electronic health records, enabling the development of multimodal biomarkers and improved patient stratification. Furthermore, patient-specific models, such as patient-derived organoids (PDOs), xenografts, and digital twin systems preserve tumor heterogeneity and microenvironmental complexity, allowing individualized drug testing and treatment prediction. The convergence of these frameworks’ advances precision oncology from a population-based paradigm toward personalized, adaptive, and data-driven cancer care. This integrative approach strengthens translational research, enhances diagnostic accuracy, and promotes more effective, patient-centered therapeutic strategies.
Perbandingan Farmakologi Obat Antituberkulosis dalam Pendekatan Terapi Jangka Panjang faradita dhiyan putri
Jurnal Sains Biomedis Vol. 1 No. 02 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i02.10596

Abstract

Tuberkulosis (TB) merupakan penyakit infeksi menular yang masih menjadi tantangan kesehatan global, terutama di negara berkembang. Terapi TB jangka panjang membutuhkan pendekatan farmakologis yang tepat, mengingat sifat unik Mycobacterium tuberculosis yang mampu bertahan dalam keadaan dorman dan kebal terhadap monoterapi. Penelitian ini bertujuan untuk membandingkan karakteristik farmakologi dari delapan obat antituberkulosis yang umum digunakan, yaitu isoniazid, rifampisin, pirazinamid, etambutol, levofloxacin, moxifloxacin, linezolid, dan bedaquiline. Studi dilakukan melalui kajian literatur deskriptif kualitatif dengan menelaah parameter farmakokinetik, farmakodinamik, efek samping, dan efektivitas terapi jangka panjang. Hasil kajian menunjukkan bahwa pemilihan regimen harus mempertimbangkan paruh waktu, rute eliminasi, target organ, dan risiko toksisitas sistemik. Terapi individual yang disesuaikan dengan kondisi pasien dan profil obat sangat penting untuk memastikan keberhasilan pengobatan dan mencegah resistensi. Studi ini menyimpulkan bahwa pendekatan rasional berbasis farmakologi sangat diperlukan dalam terapi TB jangka panjang.
TROMBOSITOPENIA DAN HEMORAGIK PADA ANAK DENGAN DEMAM BERDARAH DENGUE (DBD): KAJIAN LITERATUR Miftahuz Zakiyah; Ilham Fathurrahman; Nadya Syarifatul Fajriyah; Suharno Zen; Yuda Nabella Prameswari; Benedikta Diah Saraswati
Jurnal Sains Biomedis Vol. 1 No. 02 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i02.10612

Abstract

Dengue Hemorrhagic Fever (DHF) remains a major cause of morbidity among children in Indonesia. Thrombocytopenia is one of the key hematological abnormalities associated with progression to hemorrhagic manifestations.This review aims to summarize current evidence related to thrombocytopenia and clinical hemorrhagic features in pediatric DHF based on several Indonesian studies. A narrative review was conducted using 20 references focusing on pediatric DHF, thrombocytopenia, clinical manifestations, and disease severity.Data from the reviewed studies indicate that thrombocytopenia occurs in more than 70% of DHF cases and typically worsens around days 3–7 of fever. Hemorrhagic manifestations such as petechiae, gum bleeding, and prolonged fever duration are associated with lower platelet count and higher disease severity. Nutritional status, duration of fever, and clinical progression also influence the degree of hemorrhage in children. Thrombocytopenia is a consistent predictor of hemorrhagic complications in pediatric DHF. Early recognition of platelet decline and clinical bleeding signs is crucial in preventing progression to severe dengue.
Perbandingan Uji Sederhana Kadar Vitamin C pada Berbagai Bahan Pangan Elva Zhilianti; Nadya Syarifatul Fajriyah; Miftahuz Zakiyah; Ilham Fathurrahman; Suharno Zen
Jurnal Sains Biomedis Vol. 1 No. 02 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i02.10620

Abstract

Vitamin C atau asam askorbat merupakan zat gizi esensial yang berperan pening dalam menjaga daya tahan tubuh, membantu pembentukan kolagen, mempercepat penyembuhan luka, dan melindungi tubuh dari radikal bebas. Penelitian ini dilakukan untuk mengetahui kandungan vitamin C secara kualitatif pada beberapa bahan pangan alami seperti sari jeruk, tomat, mangga, serta minuman olahan seperti You C 1000dan Buavita jambu. Uji dilakukan menggunakan metode sederhana dengan indikator betadine (povidon iodine) sebagai oksidator. Semakin cepat larutan betadine memudar setelah dicampurkan dengan sampel, menunjukkan semakin tinggi kadar vitamin C yang terkandung di dalamnya. Hasil penelitian menunjukkan bahwa kadar vitamin C tertinggi terdapat pada sampel mangga dengan nilai 3.000%, diikuti You C 1000 dan tomat masing-masing 1.000%, sari jeruk 1.167%, dan Buavita jambu 875%. Perbedaan hasil ini dapat disebabkan oleh faktor jenis bahan, tingkat kematangan buah, serta keberadaan vitamin C tambahan pada produk olahan. Uji kualitatif sederhana ini membuktikan bahwa keberadaan vitamin C dapat dengan mudah dideteksi menggunakan reaksi reduksi-oksidasi, dan hasilnya dapat digunakan sebagai dasar edukasi mengenai pentingnya asupan vitamin C alami dari buah segar.
Tinjauan Etis dan Privasi dalam Integrasi Kecerdasan Artifisial pada Sistem Kesehatan: Suatu Ulasan Kontemporer Herera Rahajeng; Niken Rahmah Ghanny; Afifa Radhina
Jurnal Sains Biomedis Vol. 1 No. 02 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i02.10621

Abstract

Integrasi keserdasan buatan (Artificial Intelegence/AI) dalam sistem kesehatan berkembang pesat dan menawarkan potensi signifikan dalam peningkatan mutu layanan, efisiensi proses klinis, dan personalisasi terapi. Namun, pemanfaatannya menimbulkan tantangan etis dan privasi yang tidak dapat diabaikan, terutama terkait perlindungan data pribadi, transparansi algoritma, akuntabilitas keputusan klinis, serta penghormatan terhadap otonomi pasien. Artikel tinjauan ini membahas isu-isu utama dalam etika dan privasi AI di layanan kesehatan, meliputi risiko bias dan ketidaksetaraan akses, kebutuhan informed consent yang bermakna, serta pentingnya tata kelola dan regulasi yang adaptif di stingkat global. Pendekatan multidisipiner dan kerangka kebijakan yang kuat diperlukan untuk menjamin bahwa penerapan AI berlangsung secara bertanggung jawab, berkeadilan, dan tetap menjaga kepercayaan pasien. Dengan keseimbangan antara inovasi dan perlindungan hak asasi individu, AI berpotensi menjadi komponen kunci dalam mewujudkan sistem kesehatan yang lebih efektif dan berkelanjutan.

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