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Jurnal Kedokteran Diponegoro
Published by Universitas Diponegoro
ISSN : -     EISSN : 25408844     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
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Articles 974 Documents
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Factors Associated with the Non-Adherence of TB Screening in Children Aged Lidwina Vania Shaynaputri; Anindita Soetadji; Dea Amarilisa Adespin; Stefani Candra Firmanti
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.30184

Abstract

Background: TB screening in children having close contact with smear-positive TB patients is urgent to conduct to improve the case detection rate and to achieve the “End TB” target. In fact, the implementation of screening in Indonesia is still inadequate.Objective: To analyze the factors associated with the non-adherence of TB screening in children aged <15 years with smear-positive TB patients’ close contact.Methods: A cross-sectional study was conducted in Semarang between February and August 2020. Subjects were children <15 years old with smear-positive TB patient's close contact. Data were collected from interviewed parents or guardians of the child using a structured questionnaire. Chi-square or Fisher's exact test analysis was used to identify the factor associated with non-adherence to TB screening in children.Results: A total of 84 children were recruited into this study. The proportion of children who did not undergo the screening is still high (86,9%), and there was a significant association with children's age (OR 13,556, 95% CI=3.135-58,613), parents' age (OR 41,143, 95% CI=4,025-420,604), parents’ education level (OR 0,114, 95%CI=0.027–0.477), distance to health facilities, knowledge level, perceived barriers, and cues to action. There was no significant association between children’s gender, economic level, perceived threats with non-adherence of screening.Conclusion: Children and parents’ age, education level, distance to health facilities, knowledge level, perception of barriers, and cues to action associated with the non-adherence of TB screening in children aged <15 years with smear-positive TB patients’ close contact.
MELATONIN CAN NOT SIGNIFICANTLY REDUCE BLOOD SUGAR LEVELS Christiana Rinalda; Taufik Eko Nugroho; Lusiana Batubara; Asih Budiastuti
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.29491

Abstract

AbstractBackground: Burn are trauma that can cause local and systemic damage including hypermetabolism, inflammation, and hyperglicemia. Stress Induced Hyperglycemia (SIH) occurs by increasing gluconeogenesis and insulin resistance. Both of these are mediated through an increase in regulated stress hormones and proinflammatory cytokines. Melatonin has been proposed as a burn supportive therapy that may prevent oxidative damage and inhibit excessive inflammatory responses.Aim: Proving the effects of melatonin supplementation on blood glucose level in male Wistar rats with burn injury.Methods: This research was an experimental with randomized control group pre-post test design. Twelve healthy male Wistar rats were included and divided into two groups, control and experimental group. Each rat was induced 30% burn injury under anesthesia. Rats in control group were given placebo, while rats in experimental group were treated with melatonin i.p at 0, 8 and 16 hours after burn injury. Blood samples were collected from the retroorbital sinuses at 0, 3, and 24 hours. Data were analyzed statistically by Paired t-Test and Independent t-Test. Results: In male Wistar rats with third degree burns given placebo, blood sugar levels significantly increase in 0-3 hours (p=0.006)  and 0-24 hours (p=0.037). Meanwhile, in male Wistar rats with third degree burns given melatonin, blood sugar levels did not change significantly in 0-3 hours (p=0.470), 0-24 hours (p=0.286), dan 3-24 hours (p=0.833). Conclusions: Melatonin administration can not significantly reduce blood sugar levels.Keywords: Burn, burn injury, blood glucose level, melatonin.
DIFFERENCES IN OCULAR SURFACE DISEASE INDEX SCORE IN PATIENTS BEFORE AND AFTER COMBINATION OF PHACOEMULSIFICATION AND TRABECULECTOMY. Avri Panggabean; Riski Prihatningtias; Arief Wildan; Maharani Cahyono
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30027

Abstract

AbstractBackground: Dry eye is a disturbance on the surface of the eyeball marked by the loss of tear layer homeostasis, which can occur due to the instability and hyperosmolarity of tear film, inflammation or damage to the surface of the eyeball, and neurosensory abnormalities. Some surgical interventions related to the anterior part of the eye can cause symptoms of dry eye, one of which is facotrabeculectomy is a combination of surgical intervention performed in glaucoma patients with cataracts. One examination to evaluate the symptoms of dry eye is to use the Ocular Surface Disease Index (OSDI) questionnaire.Objective: This study aims to observe the difference in Ocular Surface Disease Index (OSDI) scores in patients before and after surgery combined with phacoemulsification and trabeculectomy.Methods: Analytic observational research with one group pretest and posttest research design. With a large sample of 18 respondents who were evaluated by the OSDI questionnaire in patients before and two weeks after facotrabeculectomy. Hypothesis testing with a paired T-test.Results: The results showed that before the surgery for facotrabeculectomy, the average OSDI score was 50.4628 ± 7.9429. After two weeks postoperatively the results of the study showed the average OSDI score was 58.7972 ± 7.7155. Hypothesis testing showed that OSDI scores before and after facotrabeculectomy surgery were significant differences (p = 0.001 / p <0.05).Conclusion: There were significant differences in OSDI scores in patients before and after facotrabeculectomy surgery.
Histopathology of Seminiferous Tubules of Wistar Rats (Rattus norvegicus) Exposed to Electric Mosquito Repellent with Active Ingredient D-Allethrin Salwa Nabila Izzati; Desy Armalina; RR. Mahayu Dewi Ariani; Fanti Saktini
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.31588

Abstract

Background: An increase in mosquito-borne diseases has resulted in the use of mosquito repellents, especially electric ones in Indonesia. One of the active ingredients of electric mosquito repellent, namely d-allethrin, cangenerate free radicals resulting in oxidative stress. Oxidative stress on the testes can interfere with the spermatogenesis stage in the seminiferous tubules.Objective: Determine the histopathology of seminiferous tubules of Wistar rats exposed to electric mosquito repellents with the active ingredient d-allethrin.Methods: This study used a true experimental design with a post test only control group design. A sample of 25 Wistar rats was divided into 5 groups. The control group (K) was given only standard feed. Treatment group 1 (P1), treatment group 2 (P2), treatment group 3 (P3), and treatment group 4 (P4) were exposed to electric mosquito repellents with active ingredient d-allethrin sequentially for 8 hours/day, 12 hours/day, 18 hours/day, and 24 hours/day. After 30 days the rats were terminated. The testes were taken for histopathological observation with HE staining and assessed according to the Johnsen score criteria.Results: Based on the score, the mean value of the control group was 9.4, P1: 8.36, P2: namely 7.68, P3: 5.84, and P4: 5.64.The results of statistical tests using the one way Anova showed a significant difference (p <0.001).Conclusion: Exposure to electric mosquito repellent containing the active ingredient d-allethrin caused differences in the histopathology of seminiferous tubules score of Wistar rats.
THE EFFECT OF SUBMERSION IN ORANGE JUICE AND FERMENTED MILK ON COLOR CHANGES OF NANOHIBRID COMPOSITE RESIN Attila Yulaicha; Diah Ajeng Purbaningrum; Dwi Retnoningrum; Ariosta Ariosta
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.30459

Abstract

Background: Color changes in nanohibrid composite resins can occur due to 2 factors, intrinsic and extrinsic factors. Beverage can be the one of the extrinsic factor such as orange juice and fermented milk. The pH content of this both of drink will affect the change in color of the composite resin. Low pH conditions will cause the release of H+ which has an impact on the degradation and breaking of polymer chain bonds. Aim: To determine the effect of orange juice and fermented milk on the color change of nanohibrid composite resin. Methods: An experimental study with the post test control group design and a total sample of 6 samples. Soaking for 24 hours at 37ºC in artificial saliva, orange juice, and fermented milk. After 24 hours the color changes were measured using a colorimeter. Statistical test using Independent T-test.Results : Significant differences in color changes in nanohibrid composite resins between the two sample groups (p = 0.00). Independent T-test showed the results of a significant difference between 2 groups.Conclusion: Orange juice affect the change in color of nanohibrid composite resin. There was a significant difference between orange juice and fermentedKeywords: Nanohibrid composite resin, Color change, Orange juice, Fermented milk.
CHARACTERISTIC OF MAMMOGRAPHY COMPARED WITH HISTOPATHOLOGY RESULT AT RSUP DR. KARIADI Molly Inta Sari; RR Lydia Purna Widyastuti Setjadiningrat Kuntjoro; Edmond Rukmana Wikanta; Sukma Imawati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30166

Abstract

AbstractBackground: Breast tumors are common lesions found in women.[1] Mammography is Food and Drugs Administration (FDA) approved modality for screening and diagnosing breast tumor.[2,3] Aim: To know the characteristic and comparison of mammography results with histopathology diagnosis as the gold standard in breast tumor patients at RSUP Dr. Kariadi. Methods: This research used the diagnostic test method. Data were taken from medical records in RSUP Dr. Kariadi, Semarang from 2017 to 2019 with sa consecutive sampling method. The collected samples were 55 mammography imaging. Next, the data were described as frequency distribution and percentages, and then the diagnostic test values were counted. Result: Benign breast tumor in RSUP Dr. Kariadi was found in 40-50 years old patients with 77,8% oval-shaped and 72,2% circumscribed margin mass seen in the mammogram, while breast cancer was found in >50 years old patients with 57,1% irregular-shaped and 54,3 spiculated margin mass seen in the mammogram. Mammography in RSUP Dr. Kariadi has 89% sensitivity, 89% specificity, 94% positive predictive value, 81% negative predictive value, and 89% accuracy. Conclusion: Benign breast tumor in RSUP Dr. Kariadi mostly found in 40-50 years old patients with oval-shaped and circumscribed margin mass seen in the mammogram, while breast cancer is mostly found in >50 years old patient with irregular shape and spiculated margin mass seen in the mammogram. The diagnostic test score of mammography in RSUP Dr. Kariadi is high.
Relationship of Sleep Quality with Short-Term Memory and Reaction Time in First Year Medical Students of Diponegoro University Rizki Gatot Febrian; Santoso Jaeri; Muflihatul Muniroh; Darmawati Ayu Indraswari
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.31391

Abstract

Abstract Background: Sleep disturbance is a disorder that includes a lack of quantity and quality of sleep. Students, especially medical students, have a high risk of getting sleep disorders of poor sleep quality and quantity. Poor sleep quality can interfere with memory. Besides, poor sleep quality also results in fatigue, which can lead to increased reaction time.Aim: To determine the relationship between sleep quality and short-term memory and reaction time in first-year medical students of Diponegoro University.Methods: This Observational study used a cross-sectional design with first-year medical students of Diponegoro University as the subjects. Kolmogorov-Smirnov was applied as the normality test, then the hypothesis test between sleep quality and short-term memory used the Pearson Chi-Square test, while sleep quality and reaction time used the Mann-Whitney U test. Results: Two hundred students participated in the study. Eighty two people (41%) had good sleep quality, 118 people (59%) had poor sleep quality. The p value of the relationship between sleep quality and short-term memory showed insignificant result (p=0.791). Meanwhile, the Mann-Whitney test to measure the relationship between sleep quality and reaction time was also insignificant (p=0.270).Conclusion: There is no significant relationship between sleep quality with reaction time and short-term memory in first-year medical students of Diponegoro University.
FACTORS RELATED TO ECTOPIC PREGNANCY IN RSUD R.A KARTINI JEPARA Muhammad Fikri Hanif Raza Pradana; Yuli Trisetiyono; Bambang Hariyana; Muhammad Besari Adi Pramono
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30010

Abstract

Background: Ectopic Pregnancy (EP) is a pregnancy outside the womb that ends with a rupture. Bleeding is one of the causes of the increase in Maternal Mortality Rate (MMR) by 24.5% in Central Java Province in 2017. Research to determine the factors associated with the occurrence of EP needs to be known so that the incidence of EP and MMR in Indonesia can be controlled.Purpose: This study aimed to see the incidence of EP and analyzing the relationship between age and parity with the incidence of EP in RSUD R.A Kartini Jepara.Methods: This study used an analytic observational method with a case-control research design. Sampling was done by consecutive sampling method. A total of 83 samples met the inclusion criteria, which were divided into 51 pregnant women with EP and 32 pregnant women without EP. Data were analyzed using descriptive test and Chi-square test. The factors assessed were age and parity. Other variables contained in medical records are included in the form of descriptive data.Results: The incidence of EP in RSUD R.A Kartini Jepara was 0.4% in 2017, 0.5% in 2018, and 0.3%  in 2019. In EP patients, it was found that 54.9% of patients had an education level of junior high school, 58.8% of patients had a salpingectomy procedure, 92.1% of patients whose EP location was in the tube and 60.7% of patients needed inpatient services for >4 days. The results of the bivariate analysis using the Chi-square test showed a significant relationship between parity (p = 0.029) and the incidence of EP (p <0.05). Meanwhile, age (p = 0.897) did not show a significant relationship with the incidence of EP (p> 0.05).Conclusion: The incidence of EP in RSUD R.A Kartini Jepara in was 0.4% in 2017, 0.5% in 2018, and 0.3%  in 2019. There is a relationship between parity and the incidence of EP. Meanwhile, age is not related to the incidence of EP in RSUD R.A Kartini Jepara. Keywords: Ectopic Pregnancy, Age, Parity
EFFECT OF COUNSELING ON KNOWLEDGE ATTITUDE AND BEHAVIOR OF TEXTILE INDUSTRY WORKERS ABOUT NIHL Armabar Dwipantara Sasongko; Dwi Marliyawati; Kanti Yunika; Zulfikar Naftali
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30138

Abstract

Background: Noise Induce Hearing Loss (NIHL) is a work accident which has a high incidence rate of workers ini the manufacturing industry nowadays. Attitudes and obedience behavior of manufacturing workers in using personal noise protective equipments are influenced by their knowledge about NIHL. Providing information such as health education periodically is needed to increase worker’s knowledge to change their attitudes and behaviors in order to obey safety regulations and using personal noise protective equipments.Objective: This study examines the effect of providing health counseling on the knowledge, attitudes, and behaviors of textile industry workers regarding noise induce hearing loss.Methods: This research method used quasi-experimental research method, with a one group pretest-posttest as design approach. Intervention of this research was a health counseling and the research instruments were leaflets, modules, and lectures about noise induced hearing loss. The subjects of this study were 35 workers of textile factories. Consecutive sampling were used to get subjects. Data on the level of knowledge, attitudes, and behavior were obtained through questionnaires before intervention and two weeks after the intervention was carried out. This research was located in one of the textile factories in Semarang Regency in 2020. Statistical analysis used Wilcoxon test, Fisher test, and Kolmogorov-Smirnov test.Results: The result of this research show that there was an increase in the mean score of subjects’s knowledge, attitudes and behavior. Statistical analysis show that that there is a significant differences between knowledge scores (p value = 0,000), attitudes scores (p value = 0,000), and behavior scores (p value = 0.024) before and after being given health education.Conclusion: The mean score of knowledge, attitudes and behavior of workers after being given information about noise induced hearing loss is higher than the average score of knowledge, attitudes and behavior of workers before being given a counseling.
THE EFFECT OF CARBONATED, ISOTONIC AND YOGHURT DRINKS IMMERSION ON THE ROUGHNESS OF BULK-FILL COMPOSITE RESIN Ayu Khoirun Nisa; Diah Ajeng Purbaningrum; Lusiana Batubara; Faizah Fulyani
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.30521

Abstract

Background: Composite resins are dental restorative materials that are widely used and have high aesthetic value compared to other materials. However, acidic environmental conditions can degrade the composite resins, resulting in increased surface roughness of the resin, and consequently lead to an increased risk of caries.Objective: the purpose of this study was to evaluate the effect of immersion in acidic drinks on the surface roughness of composite resins,Method: In this study 24 samples of bulk fillTM  composite resins were used. Samples were divided into four groups. Each sample was immersed for 5 seconds in either artificial saliva (control), carbonated beverage, isotonic, or yogurt, and followed by 5 seconds immersion in saliva. This cycle was repeated for 20 times for 14 consecutive days. The roughness of composite resin before and after 14 days immersion was measured by using a profilometer. Microscopic structures were analyzed by Scanning electron Microscope (SEM). Statistical analysis was used paired t-test, Anova and Post Hoc LSD.Results: Data from each sample group was normally distributed- with p > 0.05. The paired t-test for each group showed a p-value < 0.05, which indicates there was a significant difference between surface roughness before and after immersion. ANOVA analysis revealed that there was a difference in the surface roughness between groups LSD test, showed that there was difference in the surface roughness between artificial saliva with carbonated drink, isotonic drink with carbonated drink, yoghurt drink with carbonated drink (p<0.0001), between artificial saliva group with yoghurt drink, yoghurt drink with carbonated drink, yoghurt drink with isotonic drink (p <0.05) which means there was a significant difference between group. Meanwhile, the isotonic drinks with artificial saliva obtained results (p>0.05), which means there is no significant difference.Conclusion: Exposure of carbonated drinks, yoghurt drinks, and isotonic drinks can significantly increase the roughness of the surface Bulk Fill resin composite compared to exposure of artificial saliva.Keywords: Composite resin, Bulk Fill, Surface Roughness, Acid

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