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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 103   104   105   106   107 
The droplet size changes of 1% propofol before and after the storage procedure for 6 and 24 hours periods Basuki Rahmat Bambang Suryono S Djayanti Sari
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Propofol (2,6-diisopropylphenol) is a popular anesthetic agent for induction and anestheticmaintenance. Propofol preparation is formulated as a lipid macroemulsion that is thermodynamicallyunstable and degraded over time, causing the enlargement of droplet size. The degradation is fasterwhen propofol emulsion preparation package has been opened. This droplet enlargement results indecreasing propofol releasing-rate and its concentration. The risk of embolism occurs whenever themean droplet size (MDS) exceeds Food and Drug Administration (FDA) limit (<0.45) and fat globulepopulation percentage >5 m (PFAT5) is <0.05%. In the daily practice, some propofol emulsionpreparation are often used although they are already opened and saved more than 24 hours. The aimof this study was to evaluate the droplet size changes of propofol emulsion preparation duringstorage. This was an observational study using cohort prospective design. The droplet size changesof sixteen propofol preparation samples were evaluated before and after storage procedure for 6 and24 hours in the refrigerator at the temperature of 4ºC. The droplet diameter was determined under alight microscope. Mean droplet size before and after storage were calculated and analyzed by oneway analysis of variance (ANOVA), followed by Tukey’s post hoc test with 95% confidence interval(p<0.05). The droplet diameter of propofol emulsion preparation increased significantly (p<0.05)after storage procedure for 6 h (MDS value were: 247 ± 22 nm) and 24 h (278 ± 29 nm) comparedto before storage (225 ± 24 nm). The PFAT5 at each interval time was 0%. There was no color andhomogeneity changing at each interval time (n=16/100% each time interval). In conclusion, there isa change of propofol emulsion preparation droplet size after storage procedure for 6 to 24 hours attemperature of 4ºC compared to before storage.
Test Sensitivitas pada kasus-kasus Klinik yang sukar Diobati dengan Beberapa Macam Antibiotika Dan Chemotherapeutika Trihendrokesowo Trihendrokesowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 02 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

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Dyslipidemia in type II diabetes mellitus: Pathophysiology and therapeutic approach Adiwijono Adiwijono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 04 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Dyslipidemia occurs commonly in type II diabetes mellitus. Although all classes of lipoprotein may be involved, the most common lipid abnormality is increased triglycerides levels. The metabolic abnormalities associated with diabetes per se can have marked effects on serum lipids. In liver and adipose tissue, insulin has a key regulatory role of both lipid and carbohydrate metabolism pathways. If insulin secretion or action is abnormal, changes in fat and glucose metabolism will result. However, which changes will occur, is largely determined by the type of diabetes, the degree of insulin deficiency and the relative glycamic control. In many type II diabetes mellitus, it is likely that the etiology of dyslipidemia are multifactorial.There are three possible mechanisms that cause dyslipidemia in diabetes mellitus more atherogenic, i.e. glycosylation, oxidation and carbamylation processes. Since dyslipidemia and other risk factors for vascular diseases (obesity, hypertension, smoking) are frequently present, the approach to management must be broadly based.Association between diabetes mellitus and triglycerides, including relationship between disturbances of carbohydrate and lipid metabolism, provide the rational use of the antilipidemic agents, diet and sport.Key Words: diabetes mellitus - dyslipidemia - insulin - atherosclerosis - hypolipidemic agents
Wilms tumor associated with Cushing 's syndrome - A case report Madarina Julia Madarina Julia
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Ectopic ACTH syndrome associated with Wilms tumor is ver
Atypical carcinoid of the lung: A case report Hanggoro Tri Rinonce;, Toddy Guntersah;, Soeripto;, J Bras
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 04 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

A 3D-year old woman came to Dr Sardjito Hospital with chief complain of dyspneu that she had since 1 month before her visit. Clinicalexamination revealed a dull percussion below. The second intercostal of the left chest. The chest X ray revealed massive pleural effusion in the left chest, could not exclude a mass in left lung. Thoracoscopic biopsy of the left lung mass was done. Macroscopic examination of lung tissue sample revealed fragmented tissue, with volumeof 0.25 cc, blackcolour, and rubberyconsistency. The diagnosis of atypicalcarcinoid with small cell carcinoma as a differential diagnosis was determined based on morphological pattern. Immunohistochemical staining examination showed expression of cytokeratin, CAM5.2, and synaptophysin, but showed negative expression of chromogranin, CD56, and TTF-1 .A diagnosis of an atypical carcinoid was confirmed based on the immunohistochemicalexamination. A very rare case of atypical carcinoid of the lung in a non-smoker 3D-yearoldwoman with morphologicaldiagnostic problem solved by immunohistochemical staining was reported.
Kesehatan untuk Kedamaian dan Perdamaian Harapan dan Tantangan bagi Profesi Kedokteran Soeprono Soeprono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 01 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Spurred by a high sense of integrity and idealism to dedicate oneself to the cause of humanity, with a well-organized fraternity encompassing the world, the medical profession is in a strong position to foster the individual's inner peace and global peace. This can be done by well-directed efforts to strengthen health for the individual, the family and the community, through vocational training and education and limitation of population growth in balance with its productivity. Also through more concerted efforts to abolish poverty and to motivate people in pursuing a better life, materially, intellectually and spiritually. To voice moral indignation at injustice, cruelty, crime, exploitation and oppression of an individual or a nation-by another individual or nation, To stress the importance for science and technology to be dedicated to peaceful uses, and to condemn the nuclear race and the use of nuclear armament in settling international conflicts. It is a duty to preserve life's environment and to contribute in building a new and better world, socially, economically and culturally, based on equality, freedom, justice and fair distribution of material and spiritual wealth. It should be realized that the pursuit of peace in the world should start with and be based upon the attainment of the individual's inner peace. Key Words: medical profession — peace studies — environmental preservation — abolishment of nuclear war — medical ethics
Larutan garam gula untuk dehidrasi Moenginah P.A Moenginah P.A
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 04 (1978)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keyword : Larutan garam gula, dehidrasi
Penile fracture. Is it the management problem for the urologist in the rural? Prawito Singodimejo Prawito Singodimejo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 02 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Fracture of the penis is a rupture of the corpus cavernosum due to blunt trauma. In the West the penile fracture is commonly resulted from trauma in sexual intercourse but in the Middle East and Mediterranean is predominantly due to masturbation. The other causes are unconscious nocturnal manipulation or fall onto the erecting penis. We present a penile fracture case, one of the less frequent urological traumas, referred to the Sardjito Hospital. The report illustrated a 23 year old circumcised male, who had suffered from penile fracture while his penis was erecting. He was referred to the hospital by a general practitioner two days after the incident. Immediate surgical repair was done with the indication of specific history and severe hematoma in the penis as the clinical presentations. The patient was discharged on day 8 postoperation. A mild hematom was present in the wound and no sign of infection.Discussion about penile fracture written in the literature by authors is presented.Key words: penile fracture, causes, urologist problem, surgical repair. 
The correlation between blood glucose control obesity and diabetic duration, with frequency of dermatophytosis among type II diabetic patients. Dwi Retno AW Dwi Retno AW
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 01 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Objectives: The aim of this study was to determine the correlation of blood glucose control and frequency of dermatophytosis among type II diabetic patients. In addition we also assessed the dermatophytosis in correlation with obesity and diabetic duration.Materials and Methods: The study was performed using a cross-sectional study design. The subjects of this study were 180 type II diabetic patients, divided into two groups of blood glucose level (good and poor glycemic control groups). In addition, these subjects were examined for evidence of dermatophytosis, and compared between good glycemic control and poor glycemic control. Among the subjects suspected to have dermatophytosis lesions were further examined using potassium hydroxide and fungal cultures.Results: The result showed that there was seemed to be an increased frequency of dermatophytosis in poor glycemic control group in comparison with the good glycemic control group (8.3% vs 6.1 %). Statistically this difference was significant (p0.05). The combination of glycemic control and obesity in this study was seemed to have a significant correlation too.Conclusion: poor glycemic control and or obesity increased the risk for suffering from dermatophytosis in the type II diabetics, while the diabetic duration did not increase.Keywords: dermatophytosis - type II diabetes - glycemic control - obesity - diabetic duration
Prognostic factors for constipation following primary surgery of anorectal malformations in Yogyakarta, Indonesia Willy Hardy Marpaung; . Rochadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 47, No 01 (2015)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (247.48 KB) | DOI: 10.19106/JMedSci004701201503

Abstract

ABSTRACT Anorectal Malformation (ARM) is a congenital malformation of the anorectal area, occur approximately once in every 5000 live births. There are several morbidities could occur after surgery in ARM. Constipation is the most common morbidity post-surgery in ARM. This study was conducted to evaluate the prognostic factors affecting constipation in postoperative anorectal malformation. This was a case control study involving 74 children who undergo surgery in Dr. Sardjito General Hospital, Yogyakarta from 2008 to 2012. The prognostic factors are sex, type of ARM, age, type of ostomi, type of anoplasty operation, dehiscence of anoplasty, and anal dilatation. There were 41 (55.4%) male patients and 33 (44.6%) female patients in this study. The risk of constipation in the patients with high level ARM was lower than in low level ARM with an OR of 0.150 (95% CI=0.032 - 0.711; p=0.008). Abdominoperineal pullthrough had higher risk for constipation than non abdominoperineal pullthrough (PSARP and ASA) with p = 0.003. The constipation rate was also different between patients with and without dehiscence of anoplasty with an OR of 0.139 (95% CI=0.033 - 0.584; p=0.005). The gender, types of colostomy, types of colon for colostomy, age of primary operation, and frequency of anal dilatation did not affect the constipation rate. In conclusion, postoperative constipation is still a major problem in surgical for anorectal malformations in Yogyakarta. Types of anomaly, primary operative procedures, and dehiscence of anoplasty operation are the prognostic factors that affect the constipation in anorectal malformations.

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