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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 145   146   147   148   149 
Congenital cataract: A case report of two sisters Hartono Hartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 04 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Two sisters suffering from bilateral congenital zonular cataract have been reported-. Their parents and their one and only sister were perfectly normal. The older sister was 2 years old whereas the younger was 8 months when they were first examined and they immediately underwent discission and evacuation. It was likely that the two cases carried autosomal dominant genes for congenital zonular cataract, either non-penetrant genes or a fresh mutation of the germ cell of one of their parents. In the former the recurrence risk was 50%, whereas in the latter such risk was practically zero. Key Words: congenital zonular cataract - autosomal dominance - non-penetrant gene - fresh mutation - recurrence risk
Menempuh Ujian Biomedis : Persiapan dan Cara-Caranya T. Jacob T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 03 (1980)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

This article discusses the aims and various kinds of biomedical examinations and their evalua • Lion, primarily to assist those preparing for such undertakings. Among those aims, examination as a measure for protection of the public against incompetence and for quality control seems to be gradually disemphasized.Practical hints and "pearls" are given for passing various examinations, ranging from quizzes and pre-practical tests to subspecialty and doctorate examinations, and from viva voce and objective examinations to clinical and thesis examinations. Candidates are advised to know beforehand the system of evaluation and grading used in their examinations which could vary from pass/fail to 0-100 scale marking, and from continuous, comprehensive assessment to grading on the class curve. The discussion dwells on special techniques and procedures, such as rapid reading, analytical reasoning. the diagnostic process, and "post-mortem" evaluation of one's performance.Key Words: biomedical examination - viva voce - clinical examination - problem solving -diagnostic process
Resistensi Mycobacterium tuberculosis terhadap beberapa obat anti tuberculosis pilihan utama dan pilihan kedua di Laboratorium Mikrobiologi FK UGM Tahun 2000 - 2004 Ning Rintiswati Ning Rintiswati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 04 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Latar Belakang: Usaha penanggulangan tuberkulosis sering terhmbat oleh penyebaran strain Mycobacterium tuberculosa yang resisten multi obat. Salah satu upaya untuk mengatasi masalah tersebut adalah dengan penyampaian informasi mengenal data resistensi kuman secara berkala.Tujuan penelitian: Penelitian dilakukan dengan tujuan mengetahui pola resistensi Mycobacterium tuberculosa terhadap beberapa obat antituberkulosis, dalam rangka pemantauan strain bakteri resisten obat, terutama di Yogyakarta.Bahan dan care: Penelitian dilaksanakan sejak Januari 2000 sampai Desember 2004 dengan menggunakan 99 isolat Mycobacterium tuberculosa di Laboratorium Mikrobiologi, Fakultas Kedokteran UGM. Resistensi isolat-isolat tersebut terhadap obat pilihan pertama dan pilihan kedua dievaluasi. Suspensi bakteri dengan kepadatan setara dengan standar Mac Farland 1 (108 cfu/ml) ditanam pada medium Lowenstein Jensen yang mengandung masing-masing obat antituberkulosis (OAT) pilihan pertama yaitu: lsoniazid/INH (1,Oug/ ml), Sreptomisin (2,Oug/mI), Rifampisin (1,Oug/m1), Ethambutol (2,Oug/m1), dan obat pilihan kedua, yaitu: Kanamisin (lug/mi), Siprofloksasin (1ug/m1), Ofloksasin (5ug/mI). Sebagai kontrol suspensi bakteri ditanam di medium yang sama tanpa obat.Hasil: Pengamatan terhadap resistensi Mycobacterium tuberculosa menunjukkan bahwa sejumlah isolat telah resisten terhadap obat pilihan pertama yang diujikan, dengan kisaran 24,24% sampai 43,43%. Resistensi terendah adalah terhadap INH (24,24%) dan tertinggi Rifampisin (43,43%), sedangkan terhadap Streptomisin terdapat resistensi sebesar 33,33% dan terhadap Ethambutol 26,26%. Resistensi terhadap OAT pilihan kedua berkisar antara 14,29% sampai 49,50%. Resistensi tertinggi terhadap Kanamisin dan terendah terhadap Ofloksasin.Simpulan: Terhadap obat pilihan pertama, 74,75% dari isolat uji telah resisten terhadap satu OAT atau Iebih, 15,15% telah resisten terhadap semua OAT, dan hanya 25,25% isolat masih peka terhadap obat yang diujikan. Sementara itu 4.04% isolat merupakan strain resisten multi-obat (MDR-TB) karena resistan terhadap INH dan Rifampisin.
The study of fauna and vectorial competency of mosquito (Diptera:Culicidae) at Satu’un Village, Muara Uya Subdistrict, Tabalong District, South Kalimantan Province Puspawati Tri Baskoro T. Satoto Mahardika A.W
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 43, No 02 (2011)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

In Indonesia, mosquito-transmitted diseases such as malaria, dengue haemorrhagic fever (DHF), and filariasis, stillbecome main public health problems. Mosquito species which usually act as disease vector are Aedes sp, Culex sp,Anopheles sp and Mansonia sp. The aim of this study was to comprehend the mosquito fauna, bionomical and vectorcompetence of Aedes sp, Culex sp, Anopheles sp and Mansonia sp at Santu’un Village, Muara Uya Subdistrict,Tabalong District, South Kalimantan Province. Man Biting method using aspirator was used to capture mosquitoes.Mosquito dissection, ELISA and immunohistochemistry were performed to find microfilaria larvae, sporozoit Sp. ofPlasmodium and dengue virus, respectively. The results showed that Cx.quinquefaciatus, Cx.tritaeniorhyncus, Cxpipiens and Cx.gelidus were exophagic. Culex quinquefaciatus and Cx.tritaeniorhyncus biting activity was began at7 – 8 pm with their biting rate were 102.5 and 44.5 mosquitoes/person/night, respectively. Anopheles umbrosuswas endophagic. Its biting activity peaked at 8 – 9 pm with its biting rate was 0.5 mosquito/person/night. Meanwhile,An. nigerimus and An.kochi were exophagic. The biting activity of An.nigerimus peaked at 8 – 9 pm with its bitingrate was 0.5 mosquito/person/night. Anopheles kochi biting activity peaked at 6 – 7 pm with its biting rate was 1.5mosquito/person/night. Aedes albopictus was found at 6 - 7 pm with its biting rate was 2.5 mosquitoes/person/night.Mansonia bonea was exophagic. Its biting activity peaked at 11 – 12 pm with its biting rate was 2 mosquitoes/person/night. The average temperature and humidity of this study were 26.14 ± 0.30o and 94.60 ± 0.48%,respectively. Culex sp. usually rested inside the house in the morning. The breeding places of mosquitoes werepuddle of water near house, water container, old/unused vehicles, footprint, and water tank. The water temperatureof the breeding place was 25 oC. Its pH was 5.6 with 0 per mil salinity. This study did not found the vector ofmalaria, DHF, and filariasis. In conclusion, four genera of mosquitoes i.e. Culex, Anopheles, Aedes and Mansoniawere found at Santu’un Village. However, vectors of malaria, DHF and filariasis were not found at this village.Key words : Culex - Anopheles - Aedes – Mansonia - fauna - vector
Biopsi hepar pada penderita malnutrition Preliminary report Tonny Sadjimin Tonny Sadjimin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 03 (1973)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: biopsi, malnutrisi, hepar, tractus digestivus
Risk factors of neonatal mortality of referred babies with birthweight of 1000- < 2500 grams Dian Murni Wardhani, Setya Wandita Ekawaty Lutfia Haksari
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 03 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Almost 16% from all of the total births in the developing countries are low birthweight babies. Low birthweight babies are an important contribution in neonatal mortality and morbidity worldwide, and contribute to almost 70% of the total neonatal deaths. Proportion of the low birthweight babies in the developing countries is 90% of the total low birthweight babies around the world, which is 20 million annually. Mortality of babies weighing 1000-< 2500 grams in Dr. Sardjito Hospital reached 51.4%, and that of referred babies was 74.6%. Objectives: This research was aimed to find out and measure the risk factors that contribute to the mortality of referred low birthweight babies in the neonatal period. Methods: A hospital-based research with case-control study design was done to discover the risk factors that related to the neonatal mortality of the referred babies with birthweight of 1000- < 2500 grams. Data were collected from babies' medical records treated in the Maternal-Perinatal Installation of Dr. Sardjito Hospital in 2005 to 2007. Target population of this research was the mentioned above who died at the age of 0-28 days. Variable analysis to find out the correlation between the risk factors and the mortality used odds.ratio (OR), 95% confidence interval (95% CI), and the significance level with Chi-square test. To measure the risk factors that contributed on the mortality multivariate logistic regression analysis was used. Result: This study involved 190 babies (95 cases and 95 control) weighing between 1000 and < 2500 grams, who were referred to Dr. Sardjito Hospital. Several subjects were excluded, 23 babies because of going home on selfrequest, 24 because of incomplete status, 76 because of severe congenital anomaly, and 34 were extremely low birthweight babies. Sepsis (OR: 5.054, 95%CI2.433-11.198), HMO(OR:4.461, 95%CI1.595-10.497), hypoglycemia (OR: 3.358, 95%CI1.679-6.715), and hypothermia (OR: 2.221, 95%CI1.082-4.560) were the risk factors of mortality. Conclusion: Sepsis, HMO, hypoglycemia, and hypothermia increased the mortality risk of babies weighing 1000-< 2500 grams referred to Dr. Sardjito Hospital, Yogyakarta. Key words: low birthweight baby -risk factor -referral -neonatal death
Pengalaman Pengobatan Depresi Dengan Nomifensin R.Soejono Prawirohardjo R.Soejono Prawirohardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 17, No 02 (1985)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The paper describes the epidemiology and pathology of depression. The history of therapy against depression and in particular the neurotransmitters hypothesis is presented. A clinical trial was carried out in the Out-Patient Department of the Central General Hospital Dr. Sardjito, Yogyakarta. Twenty depressed patients with ages of 15 — 25 years were treated with Nomifensine, during two weeks period, with a daily dose of 50 mg in the morning and 50 mg at noon. Intensity of depression was tested with Hamilton Depression Rating Scale, before treatment, a week after treatment and finally two weeks after. A pairwise retest of differences between two item differences, was chosen for analysis of the means of the initial —, mid —, and terminal depression intensity. There is a significant decrease in intensity of depression between the initial and terminal evaluation. Remarkable side effects were absent in almost all the patients treated. Nomifensine in daily dose of 2 X 50 mg a day is effective in the treatment of depression. In most instances reduction in total score can be expected within 1 - 2 weeks of drug treatment. Finally, a recommendation is offered. Key Words: nomifensine - depression - neurotransmitters - psychiatry - anti-depressive agents
Dasar-dasar imunologi untuk kepentingan klinik Arjatmo Tjokronegoro Arjatmo Tjokronegoro
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 02 (1978)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keyword : imunologi
Accelerated phase of chronic mylogenous leukemia in paediatric with metabolic acidosis and poor nutritional status. A case report Riadi Wirawan Riadi Wirawan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 01 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

We reported a case of a twelve year old girl diagnosed as chronic myelogenous leukemia (CML), metabolic acidosis and poor nutrional status. The chief complaints were bulging abdomen, without abdominal pain, nausea and vomiting, accompanied by episodic pain in the lower extremities and buttocks without swelling or redness. Physical examination revealed hepatosplenomegaly, multiple lympadenopathy, body weight for age 54% of P50 and body weight for height 60% of P50; under P65. The laboratory findings were normochromic normocytic anemia, leucocytosis with shift to the left, myelocyte and neutrophil domination, thrombocytosis, hypercellular bone marrow with hyperactive granulopoiesis and megakaryocyte, erythropoiesis and NAP score decreased and the result of blood gas analysis was partially compensated metabolic acidosis with hypoxemia.Key words: Chronic myelogenous leukemia - metabolic acidosis - poor nutritional status - infection - hydroxyurea, cytosar 
Clto open heart as operative treatment of foreign body In the left ventricle removal M. Rosadi Seswandhana M. Rosadi Seswandhana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 35, No 2 (2003)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Foreign body in the left ventricle is rare and it is associated most commonly with significant trauma. The diagnosis of a foreign body in the left ventricle can be difficult. One must distinguish between foreign matter in the cardiac chamber or free-floating in the mediastinum. Our case was male, 38 years old. He presented not only with typical complaints of chest pain and dyspnea, but also with the complaint of a "foreign body" in the right of his chest after a work accident. Physical examination and serial chest X-rays on the earlier survey showed right hemothorax and foreign body appearance on the back wall of the heart. Insertion of chest tube with water sealed drainage was done as a primary treatment. On the echocardiography and fluoroscopy examination, we found foreign body appearance in the left ventricle. To prevent myocarditis, either sterile or non-sterile, with potential for other significant complications, removal of an intraventricle foreign body is always indicated. Cito open heart with heart-lung machine was performed to extract the foreign body. There was no complication after 7 month evaluation.Key words: Foreign body removal - In the left ventricle - Work accident - Cito open heart

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