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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 30 Documents
Search results for , issue "Vol 2 No 3 (2014)" : 30 Documents clear
Efek Preventif Ekstrak Etanol Kopi Robusta (Coffea canephora) terhadap Peningkatan Kadar Kolesterol Total Tikus Jantan Galur Wistar yang Diinduksi Kuning Telur Yan Agus Achtiar; Hairrudin Hairrudin; Kristianningrum Dian Sofiana
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Kopi robusta mengandung asam klorogenat (CGA) sekitar 7-14%. Asam klorogenat diduga dapat mencegah penyerapan kolesterol diusus. Penelitian ini bertujuan untuk membuktikan efek preventif ekstrak etanol kopi robusta (Coffea canephora) terhadap peningkatan kadar kolesterol total tikus. Penelitian ini adalah penelitian eksperimental laboratorium pre-post-test dengan kelompok kontrol. Dua puluh emapt ekor tikus wistar jantan usia 3-4 bulan, dibagi menjadi kelompok perlakuan K1 diinduksi kuning telur, kelompok K2 diinduksi kuning telur dan ekstrak kopi dosis terapi (0,5 mL / ekor), kelompok K3 diinduksi kuning telur dan simvastatin, kelompok K4 diinduksi kuning telur dan ekstrak kopi dosis tinggi (1 mL / ekor) selama 35 hari. Pada awal dan akhir perlakuan diambil serum darah untuk mengetahui kadar kolesterol total darah menggunakan menggunakan metode CHOD-PAP. Dalam waktu 35 hari, pemberian ekstrak kopi robusta tidak mencegah kenaikan kadar kolesterol total. Sehingga dapat disimpulkan bahwa tidak ada efek preventif ekstrak etanol kopi robusta (Coffea canephora) terhadap peningkatan kadar kolesterol total tikus wistar jantan yang diinduksi kuning telur.   Kata kunci: Hiperkolesterolemia, asam klorogenat, kolesterol total serum
Pengaruh Terapi Bermain Origami terhadap Tingkat Kecemasan pada Anak Prasekolah dengan Hospitalisasi di Ruang Aster RSD dr. Soebandi Jember (The Effect of Origami Play Therapy toward Anxiety Level on Preschool Age Children Hospitalization in Aster’s Room Ririn Halimatus Sa`diah; Ratna Sari Hardiani; Rondhianto Rondhianto
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hospitalization can cause anxiety to preschool children due to separation, lossing of control,injury and pain of body. Origami play therapy aims to minimize anxiety in preschool childrenduring hospitalization. This reasearch was intended to analyze the effect of origami play therapytoward Anxiety Level on Preschool Age Children Hospitalization In Aster’s Room of RSD dr.Soebandi Jember. This research used design approach quasy experiment with non equivalentcontrol group design. Sampling technique used quota sampling with a sample size of 30respondents divided into 2 goups. Research was conducted in Aster’s Room RSD dr. SoebandiJember. Research instrument used anxiety questionnaire modification RCMAS. Analysis of thedata used statistical test of Mann Whitney U test & Wilcoxon match pair test with 95% of CI.The research result showed that p value of Wilcoxon match pair test in experimental group was0,001 and 0,157 in control group, while by Mann Whitney obtained p value of 0,001 (p < α ; α =0,05). It can be concluded that there was an effect of Origami Play Therapy for Anxiety Level onPreschool Age Children With Hospitalization In Aster’s Room dr. Soebandi Jember. It issugested that nurses can provide origami play therapy to minimize or remove anxiety topreschool children during hospitalization.Keywords: Hospitalization, Anxiety, Origami play therapy
Pemetaan Tingkat Kerentanan Daerah terhadap Penyakit Menular (TB Paru, DBD, dan Diare) di Kabupaten Lumajang Tahun 2012 (Mapping of District Vulnerability on Communicable Diseases (Pulmonary TB, DHF, and Diarrhea) in Lumajang 2012) Laras Fitria; Pudjo Wahjudi; Dwi Martiana Wati
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Several types of communicable diseases such as pulmonary TB, DHF, and diarrhea have some similarity of physical environmental, socio economic, and host factors. Data related communicable diseases are needed to produce health information. Processing and presentation data about health in Lumajang is still very simple, that's only based on amount of cases distribution without any assessment with other factors such as physical environmental and human activity that have contributed to a health-related phenomena. The purposes of this research are to create synthesis thematic maps in the form of district vulnerability of communicable diseases with combining environmental and host factors. This type of research is descriptive study with variables are physical environmental (height and rainfall), social economic environment (category of family, population density rate, and total of family member), host (age, sex, and behavior), and prevalence rate of communicable diseases where obtained from secondary data. The data prensented in the form of vulnerability maps using crosstab. The result of synthesis thematic maps that subdistricts with vulnerable category of pulmonary TB are Klakah, Gucialit, Kedungjajang, Sukodono, Jatiroto, Lumajang, Yosowilangun, Kunir, Pasirian, Tempursari, Pronojiwo, Candipuro, and Pasrujambe. The subdistricts with vulnerable category of DHF are Senduro, Sukodono, Kunir, dan Rowokangkung. The subdistricts with vulnerable category of diarrhea are Senduro, Sukodono, Kunir, dan Rowokangkung. The most of subdistricts are invulnerable on communicable diseases. Keywords: Mapping, vulnerability, communicable diseases.
Optimasi dan Formulasi Tablet Mengapung - Mucoadhesive Glimepirid dengan Kombinasi Polimer Karbopol dan HPMC K4M (Optimization and Formulation Floating - Mucoadhesive Glimepiride Tablet with Combination Carbopol and HPMC K4M) Hery Diar Febryanto; Lusia Oktora Ruma Kumala Sari; Eka Deddy Irawan
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Glimepiride is one of the preferred drug for the treatment of type II diabetes mellitus. Diabetes can affect gastric emptying time. Incomplete absorption of drugs often result in small bioavailability. Glimepiride was chosen as model drug because it has incomplete absorbtion due to less gastric residence time. Tablet make by direct compression using polymer carbopol, HPMC K4M and other additives. This study used factorial design. Factors that are optimazed are carbopol and HPMC K4M and responses used are floating lag time, floating duration time, mucoadhesive, dan DE 720. tablet were evaluated for invitro release characteristic for 12 hours. Area optimum obtained on the composition of the combination of Carbopol 69.20 to 70.60 mg and HPMC K4M 10.66 to 24.67 mg.   Keywords: glimepiride, floating mucoadhesive tablet, release kinetics, carbopol, HPMC K4M
Perpanjangan Waktu Perdarahan pada Pemberian Perasan Bawang Merah (Allium ascalonicum) (The Effect of Red Onion Juice (Allium ascalonicum) to Prolongation of Bleeding Time) Liliani Saputri Lijaya; Winny Adriatmoko; Zainul Cholid
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Bleeding is one of many deathscauses. In the dentistry, bleeding can be encountered such as post-surgery. Excessive bleeding may be caused by the consumption of drugs or certain foods. Red onion (Allium ascalonicum) is one of vegetables that isconsumed by people. It wasestimated to be able to affect bleeding because containedquercetinwhich effected on adhesion, aggregation, and platelet secretion. This study aimedto determine whether redonion juice couldcause prolongation of bleeding time in wistar rats. This study wasan experimental research laboratory. The researchsampleswere 28 wistar rats,divided into 4 groups. Samples were adapted for 1 week, then they were given the treatment each group, the group I was given distilled water, group II was given red onion juice 0,562 mg/g BB, group III was given red onion juice 1,125 mg/g BB, and the fourth group was given 2,25 mg/g BBred onion juice orally. Then we cut edge 1 cm long rat tail and every 30 seconds the blood that dripped out on absorbent paper until the bleeding stops, so we got the bleeding time in each sample. The results showed that there were significant differences between the four groups of samples. The conclusion of this study wasredonion juice couldcause prolongation of bleeding time in wistar rats, with the greatest prolongation of bleeding time at dosage of 2,25 mg/g BB, then the dosage of 1,125 mg/g BB, and the smallest at 0,562 mg/g BB of dosage. Keywords: bleeding time, platelet, quercetin, red onion
Pengaruh Perawatan Luka Menggunakan Madu terhadap Kolonisasi Bakteri Staphylococcus Aureus pada Luka Diabetik Pasien Diabetes Mellitus di Wilayah Kerja Puskesmas Rambipuji Kabupaten Jember (The Effect of Wound Care Using Honey on Staphylococcus Aureus Bac Nuril Hudha Al Anshori; Nur Widayati; Anisah Ardiana
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Diabetic wound very easily causes complications in the form of infection caused by bacterialinvasion, and hyperglycemia condition boosts the growth of bacteria. One of the bacteria thatcan cause infection in diabetic wound is Staphylococcus aureus. Diabetic wound care can bedone with honey. Honey contains antibacterial, antioxidant and hydrogen peroxide that can killharmful germs. The purpose of this research was to identify the effect of wound care with honeyon Staphylococcus aureus colonization in diabetic wound. The research design used was a preexperimentwith one group pretest and posttest design. Sample was taken using consecutivesampling with 7 respondents. Data analysis applied dependent t-test and obtained p value of0.000 (p value <α = 0.05); it can be concluded that there is an effect of wound care with honeyon Staphylococcus aureus bacterial colonization in diabetic wounds of patients with DiabetesMellitus in work area of Public Health Center of Rambipuji Jember. The suggestion from thisstudy is to apply honey as a wound care agent because it has antibacterial activity that can helpprevent infection and accelerate wound healing.Keywords: wound care, diabetic wound, honey, Staphylococcus aureus
Deteksi Kemurnian Air Zamzam Menggunakan Metode Spektrofotometri Near Infra Red (NIR) dan Kemometrik (Detection of Zamzam Water Purity Using Near Infra Red Spectroscopy (NIR) and Chemometrics) Irwin Ulil Hidayah; Bambang Kuswandi; Lestyo Wulandari
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Zamzam water is called the holy water that is located in the heard city of Mecca. Zamzam is believed to have many benefits for health so widely consumed by Moslems throughout the world. In 2010, the Government of Saudi Arabia implementing rules ban export of zamzam water for commercial purposes, but zamzam water are sold freely in the world. In this research, the determination of the purity of Zamzam water was developed. The method used was NIR spectroscopy combined with multivariate statistical methods (chemometric). Zamzam water simulation were consist of pure Zamzam water, mineral water, and a mixture of Zamzam water and mineral water with a concentration range of 0% -100%. Chemometric model used are PLS, LDA, SIMCA, and SVM. LDA classification model is the best chemometric model with 100% recognition ability and prediction ability respectively. NIR spectroscopy and chemometric method have been applied succesfully to detect the purity of Zamzam water samples which marketed in Jember.   Keywords:zamzam water, purity, NIR, spectroscopy, chemometrics.
Pengaruh Ekstrak Air Ubi Jalar Ungu (Ipomoea batatas L.,) terhadap Jumlah Endhotelial Progenitor Cell (EPC) pada Tikus Wistar Diabetes Melitus Cynthia Parasetiayu Ariesty; Sugiyanta Sugiyanta; Heni Fatmawati
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Diabetes melitus adalah penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin, atau keduanya. Hiperglikemia menjadi faktor penentu dalam perkembangan disfungsi endotel dan penurunan kemampuan pembentukan pembuluh darah baru. Proses pembentukan pembuluh darah baru dihasilkan dari proliferasi endotel setempat dan peran dari Endhotelial Progenitor Cell (EPC) yang dapat dicegah dengan pemberian antioksidan. Salah satu tanaman yang mengandung antioksidan adalah ubi jalar ungu. Dalam penelitian ini, 25 ekor tikus dibagi menjadi 5 kelompok, yaitu 2 kelompok kontrol dan 3 kelompok perlakuan. Pemberian ekstrak dilakukan selama 14 hari melalui cara sonde dengan dosis 1,4 cc/ekor/hari, 3,5 cc/ekor/hari dan 5,6 cc/ekor/hari untuk P1, P2 dan P3. Penghitungan jumlah EPC tikus dilakukan dengan flowcytometry, selanjutnya data dianalisis dengan analisis Oneway ANOVA. Meskipun tidak berbeda secara signifikan, jumlah EPC pada tikus yang diinduksi ekstrak ubi jalar ungu lebih tinggi dibandingkan dengan kelompok tikus diabetik tanpa perlakuan). Dapat disimpulkan bahwa pemberian ekstrak air ubi jalar ungu dengan berbagai dosis tidak menunjukkan adanya perbedaan nyata terhadap kadar EPC tikus yang diinduksi diabetes mellitus.   Kata Kunci: Antioksidan, Diabetes melitus, EPC, Ubi Jalar Ungu
Fenomena Penyalahgunaan NAPZA Di Kalangan Remaja Ditinjau Dari Teori Interaksionisme Simbolik Di Kabupaten Jember (The Phenomenon of Substance Abuse among Adolescents Based on Symbolic Interactionism Theory in Jember Regency ) Hesty Damayanti Saleh; Dewi Rokhmah; Iken Nafikadini
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Substance abuse in adolescent is one of the big threat in Indonesia, in Jember regency from 2013-2014, there are 28 adolescents abuse the substance, this case was so dangerous for the future of adolescents. This research design used qualitative design with phenomenon approach and resource triangulation technique. The purpose of this research was to analysis the phenomenon of substance abuse amongst adolescents based on symbolic interactionism theory in jember regency. The informant got by purposive and obtained 4 informants. Based on the research result showed that the informants age are 22-23 years old. They began to abuse some drugs in junior high school. The main informants use cannabis. The informants use special language to communicate with others who also abuse substance. They have positive self concept before abuse substance and negative self concept after become substance abuser. substance abuse can influence the social interaction especially with their friends and society in around them. Most of the informants family’s didn’t know that informants as substance abuser, but in other hand most of their girl friend known that informants as substance abuser. Based on the research, it is necessary to give information about the dangerous of substance abuse for adolescent by increasing the role of adolescent in PIK adolescent and health school center. Keywords: Substance abuse, Adolescent, Symbolic Interactionism Theory
Jumlah Sel pada Isolat Monosit Setelah Paparan Tunggal Radiasi Sinar X dari Radiografi Periapikal (The Total of Cells on The Isolated Monocytes After Single Exposure of X-Ray Radiation from Periapical Radiography) Karina Ardiny; Supriyadi .; Sonny Subiyantoro
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Periapical radiography projection is one of the most frequently used in dentomaxilofacial radiographs. The radiation source used in periapical radiographs are X-ray of ionizing radiation. The use of ionizing radiation can cause harmful effects to the body, where one of it is to the blood cells. The aim of the study was to determine the effect of a single exposure of X-ray radiation from periapical radiograph towards the total of cells on isolated monocytes. The design of the study was the Post Test Only Control Group Design.This research was conducted in the Radiology Installation Bioscience and in the Laboratorium of the Jember University Dental Hospital. The research sample was isolated monocyte cells derived from human peripheral blood (dependent variable). The sample was divided in to 2 groups randomly (the control group and the treatment group). The sample size used for the research is 6 samples in each group. The treatment group was given a single exposure periapical radiography of X-ray radiation at a dose of 1.54 mGy (independent variable). The living cells on isolated of monocytes were observed and calculated using an inverted microscope with 400x magnification using a trypan blue staining. The results of research used the Independent T-test found a significant difference (p<0.05) between the control and treatment groups. The conclusion of the research was that decreasing (31,53%) in the total of cells in isolated monocytes after a single exposure of X-ray radiation from periapical radiography.   Keywords: Monocyte, Periapical Radiograph, X-Ray Radiation

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