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Jurnal Anestesi Perioperatif
Published by Universitas Padjadjaran
ISSN : 23377909     EISSN : 23388463     DOI : 10.15851/jap
Core Subject : Health, Education,
Education Health Professions
Jurnal Anestesi Perioperatif (JAP)/Perioperative Anesthesia Journal is to publish peer-reviewed original articles in clinical research relevant to anesthesia, critical care, case report, and others. This journal is published every 4 months with 9 articles (April, August, and December) by Department of Anesthesiology and Intensive Care Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung.
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Articles 484 Documents
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Efektivitas Pemberian Cairan Praoperatif Ringer Laktat 2 mL/kgBB/jam Puasa untuk Mencegah Mual Muntah Pascaoperasi Andi Ade Wijaya; Bona A. Fithrah; Arif H. M. Marsaban; Jefferson Hidayat
Jurnal Anestesi Perioperatif Vol 2, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1172.33 KB)

Abstract

Teknik nonfarmakologi yang dapat dilakukan untuk menurunkan angka kejadian mual muntah pascaoperasi adalah pemberian cairan praoperatif. Tujuan penelitian ini untuk mengetahui efektivitas pemberian cairan praoperatif Ringer laktat 2 mL/kgBB/jam puasa untuk menurunkan angka kejadian mual muntah pascamastektomi. Penelitian ini merupakan uji klinis acak yang dilakukan pada bulan Maret–April 2013 di Rumah Sakit Kanker Dharmais, Rumah Sakit Persahabatan, Rumah Sakit Fatmawati, dan Rumah Sakit Cipto Mangunkusumo Jakarta, pada pasien status fisik American Society of Anesthesiologist (ASA) 1–2. Sebanyak 102 pasien diacak ke dalam kelompok hidrasi dan kelompok kontrol. Analisis data dilakukan menggunakan uji chi-kuadrat. Terdapat perbedaan yang signifikan dalam kejadian mual pada 0–1 jam pascaoperasi (kelompok hidrasi 20% vs kelompok kontrol 39%) dan pada 0–24 jam pascaoperasi (kelompok hidrasi 22% vs kelompok kontrol 41%). Walaupun tidak berbeda secara statistik, angka kekerapan mual pada 1–24 jam pascaoperasi lebih rendah pada kelompok hidrasi 12% (6) dibandingkan dengan kelompok kontrol 23% (12). Tidak ada perbedaan secara statistik pada angka kekerapan muntah di kedua kelompok penelitian. Pemberian cairan praoperatif Ringer laktat 2 mL/kgBB/jam puasa efektif untuk menurunkan angka kejadian mual pascaoperasi mastektomi pada 1 jam pertama pascaoperasi.  Kata kunci: Cairan praoperatif, mastektomi, mual muntah pascaoperasi Effectiveness of Pre-operative Lactated Ringer’s Solution 2 mL/kgBW/h in Fasting Patients to Prevent Post-operative Nausea and Vomiting Non pharmacologic approaches to overcome post operative nausea and vomiting include giving pre-operative hydration. The objective of this study was to learn the efficacy of pre-operative lactated Ringer’s solution (2 mL/kgBW/hour) in fasting patients to overcome the post-operative nausea and vomiting in mastectomy surgery. This study was a randomized clinical trial that conducted in March to April 2013 in Dharmais Hospital-National Cancer Center,  Persahabatan Hospital, Fatmawati Hospital, and Rumah Sakit Cipto Mangunkusumo Jakarta to patients with  American Society of Anesthesiologist (ASA) physical status 1–2. A total of 102 patients were randomized into the hydration group and control group. Data analysis was performed using chi-square test or appropriate test using SPSS ver. 15. There were statistically significant differences in the incidence of nausea at 0–1 hour post-operative (19.6% in hydration group vs. 39.2% in control group) and at 0–24 hours post-operative (21.6% in hydration group vs. 41.2% control group). The incidence of 1–24 hours PONV, although not statistically significant, was higher in the control group (11.8% in hydration group vs. 23.5% in control group). There was no difference in vomiting incidence between the two groups. Pre-operative lactated Ringer’s solution 2 mL/kgBW/hour in fasting patients effectively reduces the incidence of post-operative nausea one hour after operation. Key words: Mastectomy, post-operative nausea and vomiting pre-operative hydration DOI: 10.15851/jap.v2n3.332
Perbandingan Epidural Volume Extension 5 mL dan 10 mL Salin 0,9% pada Spinal Anestesi dengan Bupivakain 0,5% 10 mg Hiperbarik terhadap Tinggi Blok Sensorik dan Pemulihan Blok Motorik pada Seksio Sesare Reza Indra Putra; Erwin Pradian; Rudi Kurniadi Kadarsah
Jurnal Anestesi Perioperatif Vol 4, No 1 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (420.27 KB) | DOI: 10.15851/jap.v4n1.740

Abstract

Epidural volume extension (EVE) merupakan bentuk modifikasi dari kombinasi spinal epidural dengan injeksi salin normal ke dalam rongga epidural setelah dosis intratekal. Teknik EVE meningkatkan tingkat blok sensorik yang diakibatkan efek volume saat volume cairan pada rongga epidural yang menekan dural sac dan menyebabkan penyebaran sefalad dari anestetik lokal. Tujuan penelitian ini adalah mengkaji perbedaan pengaruh EVE 5 mL dan 10 mL salin 0,9% dengan menggunakan bupivakain 0,5% 10 mg terhadap tinggi blok sensorik dan pemulihan blok motorik pada pasien seksio sesarea. Penelitian dilakukan pada pertengahan September–November 2014 di Rumah Sakit Dr. Hasan Sadikin Bandung. Dilakukan uji klinis acak terkontrol pada 30 pasien yang menjalani seksio sesarea (SC) dan dibagi menjadi dua kelompok, yaitu kelompok yang menerima EVE 10 mL dan kelompok yang menerima EVE 5 mL pada pasien yang akan dilakukan SC dengan menggunakan anestesi kombinasi spinal epidural. Penilaian ketinggian blok sensorik menggunakan uji pinprick serta penilaian pemulihan blok motorik menggunakan uji bromage score. Data hasil diuji dengan uji-t. Hasil penelitian menunjukkan pemulihan blok motorik pada subjek penelitian yang menggunakan EVE 10 mL lebih cepat pulih dibanding dengan menggunakan EVE 5 mL (p<0,001). Simpulan pada penelitian ini menunjukkan pemberian EVE 10 mL pada pasien seksio sesarea memiliki pemulihan blok motorik lebih cepat dengan ketinggian blok sensorik yang sama.Kata kunci: Blok motorik, blok sensorik, epidural volume extensionComparison between 5 mL Epidural Volume Extension and 10 mL Epidural Volume Extension by 0.9% Saline in Spinal Anesthesia with 10 mg 0.5% Hyperbaric Bupivacaine on High and Recovery Sensory Block Motor in Caesarean SectionAbstractEpidural volume extension (EVE) is a modified form of combined spinal epidural with normal saline injected into the epidural space after the intrathecal dose. EVE techniques increases the level of sensory block resulting from the volume effects when the volume of fluid in the epidural space suppresses the dural sac and causes the cephalad spread of local anesthetic. The aim of this research was to assess differences in the effects of 5 mL EVE and 10 mL EVE by 0.9% saline with 10 mg 0.5% bupivacaine on sensory block height and motor block recovery in caesarean section patients. This research was carried out from mid September to November 2014 in Dr. Hasan Sadikin General Hospital Bandung. This was a randomized controlled clinical trial conducted on 30 patients who underwent caesarean section (SC) and divided randomly into two groups, namely group receiving 10 mL EVE and group receiving 5 mL EVE with a spinal epidural combination anesthesia. The assessment of sensory block height was performed using the pinprick test while bromage score test were used for motor block recovery. The data was analyzed using t test. The results showed a faster recovery of motor block in the research subjects using 10 mL EVE compared to those using 5 mL EVE (p<0.001). The conclusion from this study is that the administration of 10 mL EVE in patients who underwent caesarean section leads to a faster motor block recovery with the same sensory block height.Key words: Block motor, sensory block, epidural volume extension DOI: 10.15851/jap.v4n1.740
Perbandingan antara Sevofluran dan Propofol Menggunakan Total Intravenous Anesthesia Target Controlled Infusion terhadap Waktu Pulih Sadar dan Pemulangan Pasien pada Ekstirpasi Fibroadenoma Payudara Arvianto Arvianto; Ezra Oktaliansah; Eri Surahman
Jurnal Anestesi Perioperatif Vol 5, No 1 (2017)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (621.483 KB) | DOI: 10.15851/jap.v5n1.1002

Abstract

Penggunaan total intravenous anesthesia (TIVA) dengan propofol terus meningkat karena mudah untuk dikendalikan, onset cepat, durasi singkat, efek samping minimal, serta pemulihan psikomotor dan kognitif lebih cepat. Teknologi target controlled infusion (TCI) diciptakan untuk mempermudah dilakukan TIVA bagi dokter anestesi. Penelitian ini bertujuan mengetahui perbandingan waktu pulih sadar dan pemulangan pasien antara teknik anestesi sevofluran dan TIVA TCI propofol. Penelitian ini dilakukan secara acak terkontrol buta tunggal terhadap 36 orang pasien bedah rawat jalan, wanita usia 18–65 tahun dengan status fisik American Society of Anesthesiologists (ASA) kelas I–II yang menjalani operasi biopsi ekstirpasi fibroadenoma payudara satu sisi di Rumah Sakit Dr. Hasan Sadikin Bandung periode Agustus–November 2015. Sampel dikelompokkan secara random menjadi kelompok sevofluran dan TCI. Kelompok sevofluran mendapatkan anestesi inhalasi sevofluran dan kelompok TCI mendapatkan anestesi TCI propofol dengan metode Schnider Effect Concentration (ec). Waktu pulih sadar dan pemulangan pasien dikumpulkan dan dianalisis menggunakan uji-t, uji Mann-Whitney, dan chi-kuadrat dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan perbandingan waktu pulih sadar pada kelompok sevofluran, 429±0,763 menit, sedangkan kelompok TCI 9,356±2,331 menit. Simpulan penelitian adalah teknik anestesi sevofluran memberikan waktu pulih sadar yang lebih cepat dan TIVA TCI propofol memberikan waktu pemulangan pasien yang lebih cepat.Kata kunci: Fibroadenoma payudara, sevofluran, TIVA TCI propofol, waktu pulih sadar, waktu pemulangan pasien Comparison of Emergence Time and Discharge Time between Sevoflurane and Propofol Using Total Intravenous Anesthesia with Target Controlled Infusion in Patients Underwent Extirpation of Breast FibroadenomaTotal intravenous anesthesia (TIVA) with propofol is increasingly used, because it is easy to control, has rapid onset, short duration, minimal adverse effects, and rapid recovery of the psychomotor and cognitive functions. This study was conducted to compare the emergence and discharge time between patients receiving sevoflurane and propofol with TCI. A single blind randomized controlled clinical trial was conducted on 36 female patients aged 18–65 years with American Society of Anesthesiologists (ASA) physical status I–II, who underwent breast fibroadenoma extirpation biopsy at the outpatient surgical unit in Dr. Hasan Sadikin General Hospital Bandung. The subjects were randomized and divided into two groups: sevoflurane group receiving inhalation anesthesia with sevoflurane and target controlled infusion (TCI) group receiving propofol TCI Schnider’s Effect Concentration (ec). The mergence time and discharge time were recorded for each group and analysis was performed using Mann Whitney test, t-test and chi-square/Fisher’s exact with 95% confidence interval. This study showed that the emergence time in sevoflurane group and TCI group were 7.429±0.763 minutes and 9.356±2.331 minutes, respectively. The result showed that sevoflurane provides shorter emergence time while TIVA with TCI propofol provides shorter discharge time.Key words: Breast fibroadenoma, emergence time, patients discharging time TIVA TCI propofol, sevoflurane 
Perbandingan Efektivitas Pemberian Efedrin Oral Dosis 25 mg dengan 50 mg Preoperatif terhadap Kejadian Hipotensi Pascaanestesi Spinal pada Seksio Sesarea Selly Oktarina Rosita; Erwin Pradian; Ruli Herman Sitanggang
Jurnal Anestesi Perioperatif Vol 1, No 3 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Tablet efedrin dapat mencegah hipotensi dengan efek samping lebih kecil. Penelitian ini bertujuan mengkaji dosis efektif tablet efedrin yang diberikan 30–45 menit sebelum dilakukan anestesi spinal untuk menurunkan kejadian hipotensi. Penelitian bersifat eksperimental acak tersamar tunggal dengan 32 ibu hamil ASA II yang menjalani operasi sesar dengan anestesi spinal di Rumah Sakit Dr. Hasan Sadikin Bandung pada bulan Maret–Mei 2012. Subjek penelitian dikelompokkan menjadi dua, yaitu kelompok 25 mg dan 50 mg. Data dianalisis dengan Uji Mann Whitney dan chi-kuadrat, nilai p<0,05 dianggap bermakna. Analisis statistik menunjukkan bahwa kejadian hipotensi pada kelompok 25 mg dan kelompok 50 mg berbeda bermakna (p=0,049). Pada kelompok tablet efedrin 25 mg kebutuhan efedrin intravena pascaanestesi spinal lebih besar (p=0,040). Simpulan penelitian ini adalah pemberian tablet efedrin 50 mg 30–45 menit sebelum anestesi spinal dapat mencegah hipotensi pascaanestesi spinal lebih baik dibandingkan dengan tablet efedrin 25 mg. Kelompok tablet efedrin 25 mg memerlukan jumlah pemberian efedrin intravena lebih banyak dibandingkan dengan kelompok tablet efedrin 50 mg.Kata kunci: Anestesi spinal, efedrin tablet 25 mg, efedrin tablet 50 mg, seksio sesarea, hipotensi Comparison of the Effectiveness of Preoperative Oral 25 mg and 50 mg Ephedrine on Postspinal Anaesthesia Hypotension in Caesarean SectionAbstractOral ephedrine is one alternative to prevent hypotension with less adverse effects. The purpose of this study was to determine the effective dose of oral ephedrine given 30–45 minutes before spinal anesthesia to reduce incidence of hypotension. The research was a single-blind randomized experimental study involving 32 pregnant women, ASA II, who underwent caesarean section with spinal anesthesia at Dr. Hasan Sadikin Hospital Bandung from March to May 2012. Subjects were divided into two groups, 25 mg ephedrine and 50mg ephedrine groups. Data was analyzed using Mann Whitney and chi-square test, p<0.05 was considered significant. Statistical analysis showed there was a significant difference (p=0.049) in incidence of hypotension between 25 mg group and 50mg group. 25mg group required more intravenous ephedrine after spinal anesthesia (p=0.040). The conclusion of this study was that oral 50mg ephedrine given 30–45 minutes before performing spinal anesthesia will reduce the incidence of hypotension after spinal anesthesia in comparison to oral 25mg ephedrine. In 25mg group, the amount of ephedrine intravenous administered is higher compared with 50mg group.Key words: Spinal anesthesia, 25mg oral ephedrine, 50mg oral ephedrine, caesarean section, hypotension DOI: 10.15851/jap.v1n3.192
Perbandingan antara Pemberian Diet Oral Dini dan Tunda terhadap Bising Usus Pascabedah Sesar dengan Anestesi Spinal Mohammer Pasha; Achsanuddin Hanafie; Muhammad Ihsan
Jurnal Anestesi Perioperatif Vol 6, No 2 (2018)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (793.064 KB) | DOI: 10.15851/jap.v6n2.1422

Abstract

Inisiasi diet pascabedah masih merupakan kontroversi pada pasien pascabedah termasuk pada pasien pascabedah sesar. Penelitian ini bertujuan membandingkan waktu kembalinya fungsi gastrointestinal yang dilihat dari munculnya bising usus antara kelompok yang menerima diet oral dini dan diet oral tunda. Uji klinis acak terkontrol tersamar ganda dilakukan pada periode bulan April–Mei 2017 di RSUP Haji Adam Malik Medan, RS Universitas Sumatera Utara Medan, dan RSU Sundari Medan. Sebanyak 40 pasien yang memenuhi kriteria inklusi dan tidak termasuk eksklusi diamati waktu munculnya bising usus pascabedah sesar dan keluhan gastrointestinal yang muncul berupa mual, muntah, dan kembung. Dari 40 pasien tersebut, 20 subjek merupakan kelompok diet oral dini dan 20 subjek lagi merupakan kelompok diet oral tunda. Data dianalisis dengan menggunakan uji chi-square dan Mann-Whitney. Munculnya bising usus tidak berbeda signifikan (p>0,05) antara kedua kelompok dan tidak ada perbedaan yang signifikan dalam hal keluhan mual, muntah, dan kembung pascaoperasi antara kedua kelompok (p>0,05). Pemberian diet oral dini dapat diberikan 2 jam pascaoperasi bedah sesar tanpa penyulit dengan anestesi spinal tanpa keluhan gastrointestinal yang bermakna.  Kata kunci: Anestesi spinal, bedah sesar, diet oral dini, diet oral tunda, keluhan gastrointestinal Comparison of Peristaltic Sound between Early and Late Oral Diet Administration  in  Post-Caesarean Section Post-with Spinal Anesthesia A controversy still exists for post-operative diet administration, including for post-post-post-caesarean section patients. The aim of this study was to compare the return of gastrointestinal function reflected by the peristaltic sound between groups receiving early oral diets and late oral diets. This was a double blind randomized controlled trial performed from April to May 2017 in Haji Adam Malik General Hospital Medan, North Sumatera University Hospital, Medan, and Sundari General Hospital, Medang on 40 patients who met the inclusion and exclusion criteria. Subjects were observed to determine the time when bowel movement started as well as for gastrointestinal complaints. Of all 40sujects enrolled in this study, 20 were provided with early oral diet nd the remaining 20 subjects received late oral diet group. Data were then analyzed using chi-square and Mann-Whitney tesst The return of peristaltic sound was not significantly different between both groups (p>0.05). No significant difference found in the occurence of post-operative nausea, vomiting, and post-bloating between the two groups (p>0.05). Oral diet may be administered safely 2 hours after uncomplicated cesarean section under spinal anesthesia without any significant gastrointestinal complaint.Key words: Cesarean section, delayed oral diet, early oral diet, gastrointestinal complication, spinal anesthesia
Perbandingan Lama Analgesia antara Kombinasi Bupivakain 0,125% dan Tramadol 1 mg/kgBB dengan Bupivakain 0,125% Melalui Blokade Kaudal pada Pasien Anak Pascaoperasi Hipospadia Viana Wijayanti; Ruli Herman Sitanggang; A. Himendra Wargahadibrata
Jurnal Anestesi Perioperatif Vol 2, No 2 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Blokade kaudal merupakan teknik anestesi regional yang paling banyak dilakukan pada operasi anak. Penelitian ini bertujuan mengetahui perbandingan lama analgesia kombinasi bupivakain dan tramadol dengan bupivakain melalui blokade kaudal pada pasien anak balita pascaoperasi hipospadia. Penelitian dilakukan terhadap 30 pasien, usia 1–5 tahun, status fisik American Society of Anesthesia (ASA) I di Rumah Sakit Dr. Hasan Sadikin Bandung pada bulan Maret hingga Mei 2010. Tipe penelitian ini adalah eksperimental, rancangan acak lengkap terkontrol, tersamar tunggal. Kelompok BT menggunakan kombinasi bupivakain 0,125% dan tramadol 1 mg/kgBB  dan kelompok B menggunakan bupivakain 0,125%.  Data hasil penelitian diuji dengan uji-t. Lama analgesia pascaoperasi pada kelompok BT lebih panjang dibandingkan dengan kelompok B dengan hasil yang sangat bermakna (p<0,01). Kelompok BT dengan lama analgesia 531,33 (SD 42,86) menit dan kelompok B, 370,00 (SD 37,37) menit.  Simpulan penelitian ini adalah penggunaan kombinasi bupivakain 0,125% dan tramadol 1 mg/kgBB (0,5 mL/kgBB) untuk blokade kaudal  sebagai analgetik pascaoperasi hipospadia, menghasilkan lama analgesia yang lebih panjang bila dibandingkan dengan bupivakain 0,125%.  Kata kunci: Blokade kaudal, bupivakain, operasi hipospadia, tramadolComparison of the Duration of Analgesia between Combination of 0.125% Bupivacaine Mixed with Tramadol 1 mg/kgBW and 0.125% Bupivacaine Through Caudal Blockade in Toddlers after Hypospadia Surgery Caudal block is the most common regional anesthetic technique performed in pediatric surgery. This study was designed to compare the duration of analgesia of caudal block between combination of bupivacaine with tramadol and bupivacaine in toddler with hypospadia repair. Thirty American Society of Anesthesia (ASA) I toddlers, aged 1–5 years old at Dr. Hasan Sadikin General Hospital Bandung, runs from March to May, 2010. Patients in group BT, received 0.125% bupivacaine mixed with tramadol 1 mg/kgBW  0.5 mL/kgBW and group B, received plain 0.125% bupivacaine in the same total volume. This type of research is experimental. It was  a single blind randomized controlled trial. Duration of postoperative analgesia were noted. The t-test was used for analysing the data of this study. The duration of analgesia in group BT 531.33 (SD 42.86) was significantly longer than in group B 370.00 (SD 37.37) minutes with p value<0.001. Caudal administration of 0.125% bupivacaine mixed with tramadol 1 mg/kgBW resulted in longer duration of analgesia compared with 0.125% of bupivacaine.  Key words: Bupivacaine, caudal block, hypospadia repair, tramadol DOI: 10.15851/jap.v2n2.307
Perbandingan Sevofluran dengan Propofol Target Controlled Infusion (TCI) sebagai Rumatan Anestesi terhadap Waktu pulih Sadar dan Komplikasi Mual Muntah pada Operasi Timpanoplasti Desvita Rosana; Dedi Fitri Yadi; Ricky Aditya
Jurnal Anestesi Perioperatif Vol 7, No 1 (2019)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (644.603 KB) | DOI: 10.15851/jap.v7n1.1620

Abstract

Praktik anestesi membutuhkan kualitas anestesi yang baik, efek samping minimal, serta pemulihan cepat. Propofol dan sevofluran memiliki efek farmakologis pemulihan pascaanestesi yang cepat. Penelitian ini bertujuan mengetahui perbandingan sevofluran dengan propofol target controlled infusion (TCI) sebagai rumatan anestesi terhadap waktu pulih sadar dan komplikasi mual muntah pada operasi timpanoplasti. Penelitian  dilakukan periode Agustus–November 2018 di RSUP Dr. Hasan Sadikin Bandung. Penelitian merupakan prospektif eksperimental menggunakan uji klinis acak buta tunggal terhadap 44 subjek yang dibagi acak menjadi dua kelompok, yaitu kelompok propofol TCI  (kelompok P, n=22) dan kelompok  sevofluran (kelompok S, n=22). Selama operasi dicatat lama operasi, jumlah opioid, waktu pulih sadar, dan komplikasi mual muntah. Analisis statistik data numerik dengan uji t tidak berpasangan dan Mann Whitney, data kategorik dengan uji chi square. Hasil penelitian tidak ada perbedaan signifikan (p>0,05) untuk karakteristik pasien, lama operasi, dan jumlah opioid perioperatif. Waktu pulih sadar kelompok sevofluran lebih cepat signifikan dibanding dengan propofol TCI (10,26±1,91 menit dan 13,36±1,72 menit; p<0,05). Komplikasi mual muntah pascaoperasi kelompok sevofluran lebih besar signifikan dibanding dengan propofol TCI (15 dan 1; p<0,05). Simpulan, sevofluran memiliki waktu pulih sadar lebih cepat dibanding dengan propofol TCI, namun komplikasi mual muntah sevofluran lebih besar. Comparison between Effect of Sevoflurane with Propofol Target Controlled Infusion (TCI) as Maintenance of Anesthesia on Emergence Time and Nausea-Vomiting Complication in Timpanoplasty SurgeryCurrent modern anesthesia practice requires good anesthetic quality, minimum side effect, and early recovery. Propofol and sevoflurane have pharmacological properties that include fast recovery after anesthesia. The aim of this study was to evaluate the comparative effects of sevoflurane versus propofol target controlled infusion (TCI) for maintenance of anesthesia with respect to emergence time and postoperative nausea and vomiting (PONV) complication in patients undergoing timpanoplasty surgery. The study was carried out from August–November 2018 in Dr. Hasan Sadikin Bandung Hospital. It was a prospective single blind experimental study conducted on 44 subjects who were randomly divided to receive either propofol TCI (group P, n=22) or sevoflurane (group S, n=22). Duration of surgery, total ammount of opioid used, emergence time, and postoperative nausea and vomiting complication were recorded. Numerical data were tested by unpaired t test and Mann Whitney while categorical data were tested by chi-square. The results showed that patient characteristics, duration of surgery, and total amount of opioid used were not significantly different (p>0.05). Emergence time of the sevoflurane (S) group was significantly faster than the propofol (P) group (10.26+1.91 and 13.36+1.72, respectively; p<0.05). The complication of postoperative nausea and vomiting in group S was significantly higher compared to group P (15 and 1, respectively; p<0.05). It is concluded that sevoflurane has faster emergence time compared to propofol TCI, but PONV complication of sevoflurane is higher.
Perbandingan Pemberian Deksametason 10 mg dengan 15 mg Intravena sebagai Adjuvan Analgetik terhadap Skala Nyeri Pascabedah pada Pasien yang Dilakukan Radikal Mastektomi Termodifikasi M. Erias Erlangga; Ruli Herman Sitanggang; Tatang Bisri
Jurnal Anestesi Perioperatif Vol 3, No 3 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Deksametason merupakan kortikosteroid yang memiliki efek anti-inflamasi paling kuat. Penelitian ini bertujuan membandingkan deksametason 10 mg dengan deksametason 15 mg intravena prabedah terhadap nyeri pascabedah dan kebutuhan analgetik opioid. Penelitian ini merupakan uji acak terkontrol buta ganda pada 60 wanita dengan status fisik American Society of Anesthesiologist (ASA) I–II yang menjalani pembedahan radikal mastektomi termodifikasi dalam anestesi umum di Rumah Sakit Dr. Hasan Sadikin Bandung periode Desember 2013–April 2014. Pasien dibagi menjadi dua kelompok, yaitu 30 orang menerima deksametason 10 mg dan 30 orang menerima deksametason 15 mg yang diberikan 30 menit prabedah. Penilaian skala nyeri menggunakan nilai numeric rating scale (NRS) pada saat istirahat dan mobilisasi, pada jam ke-1, 2, 4, 12, dan 24 pascabedah. Pemberian analgetik tambahan opioid dilakukan bila nilai NRS>3. Analisis statistika data hasil penelitian menggunakan uji-t, chi-kuadrat, dan Mann-Whitney. Hasil penelitian menunjukan nilai NRS saat istirahat pada kelompok deksametason 10 mg dengan deksametason 15 mg tidak berbeda bermakna (p>0,05), sementara nilai NRS saat mobilisasi pada kelompok deksametason 10 mg lebih tinggi dibanding dengan kelompok deksametason 15 mg (p<0,05). Pemberian analgetik tambahan pascabedah tidak terdapat perbedaan secara bermakna antara kedua kelompok (p>0,05). Simpulan penelitian ini adalah pemberian deksametason 15 mg dapat diberikan karena mempunyai efek analgesia yang lebih baik.Kata kunci: Deksametason, numeric rating scale, nyeri pascabedahComparison between 10 mg and 15 mg of Intravenous Dexamethasone as Analgesia Adjunct on Post Operative Pain in Patients Undergo Modified Radical Mastectomy Dexamethasone is a glucocorticoid with the strongest anti-inflammatory property. The aim of this study was to compare the effect of 10 mg and 15 mg of intravenous dexamethasone on post operative pain and opioid analgetic need. This was a randomized double-blind study involving 60 females with physical status ASA I–II whom underwent modified radical mastectomy under general anesthesia at Dr. Hasan Sadikin General Hospital during December 2013–April 2014. Patients were divided into 2 groups where 30 patients received 10 mg dexamethasone and 30 patients received 15 mg dexamethasone 30 minutes prior to surgery. Pain assessment was performed using numeric rating scare (NRS) at rest and during activity, documented on the 1st, 2nd, 4th, 12th and 24th hour post operative. Additional analgesia was given if NRS >3. Data were analyzed statistically using Student’s t test, chi-square and Mann Whitney U test. Result showed that the difference between NRS at rest for 10 mg and 15 mg dexamethasone (p>0.05) was not significant, while the difference in NRS during activity at all time measurements were statistically significant (p<0.05). There was no statistical significant difference in additional opioid administered between the two groups (p>0.05). This study concludes that 15 mg dexamethasone has a better analgesia effect to reduce analgesic dose.Key words: Dexamethasone, numeric rating scale, post operative pain DOI: 10.15851/jap.v3n3.607
Hubungan Nilai Mean Platelet Volume (MPV) dengan Skor APACHE II sebagai Prediktor Mortalitas pada Pasien Sepsis Berat di Rumah Sakit Umum Pusat Haji Adam Malik Medan M. Teguh Prihardi; Achsanuddin Hanafie; Soejat Harto
Jurnal Anestesi Perioperatif Vol 4, No 3 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Sepsis berat merupakan kondisi umum di unit perawatan intensif (UPI) dan rawat inap yang berhubungan dengan mortalitas, morbiditas, dan biaya perawatan yang tinggi. Tujuan penelitian ini ingin mendapatkan skor alternatif yang lebih sederhana, yaitu nilai mean platelet volume (MPV) sebagai prediktor mortalitas pada pasien sepsis berat selain skor APACHE II. Penelitian ini menggunakan desain cross sectional pada 76 pasien sepsis berat dewasa di Rumah Sakit H. Adam Malik Medan pada Oktober 2015–Januari 2016 yang memenuhi kriteria inklusi. Data yang diambil adalah nilai MPV dan skor APACHE II pada saat pertama sekali terdiagnosis sepsis berat, kemudian dilihat mortalitas pasien tersebut. Uji korelasi Spearman menunjukkan bahwa terdapat korelasi lemah yang signifikan (p=0,006) antara MPV dan APACHE II dengan nilai r (korelasi) = 0,314. Nilai MPV pada penelitian ini tidak memiliki kemampuan dalam memprediksi mortalitas (AUC) ROC 58,2% (IK 95%: 45,1–71,2%; p=0,223); sedangkan skor APACHE II memiliki kemampuan yang sedang dalam memprediksi mortalitas (AUC) ROC 70,4% (IK 95%: 58,6–82,2%; p= 0,002). Didapatkan cut-off point untuk APACHE II adalah 19 dengan sensitivitas 65,9%, spesitivitas 65,7%, NPP 69,2%, dan NPN 62,2%. Simpulan penelitian ini adalah nilai MPV tidak dapat dijadikan prediktor mortalitas pada pasien sepsis beratKata kunci: Mean platelet volume, mortalitas UPI, skor APACHE II Correlation between Mean Platelet Volume (MPV) and Apache II Score as Mortality Predictors in Severe Sepsis Patients at Haji Adam Malik General Hospital MedanAbstractSevere sepsis is a general condition in the Intensive Care Unit (ICU) and inpatient wards which correlates with mortality, morbidity, and high cost hospitalization. The main point of this study was to explore the possibility to use the mean platelet volume (MPV) as an easier alternative score for mortality predictor in addition to APACHE II score in severe sepsis patients. This study used cross-sectional design on 76 adult severe sepsis patients in Haji Adam Malik General Hospital Medan who met inclusion criteria during the periood of October 2015 to January 2016. Data collected were MPV value and APACHE II score, which were collected the first time patient was diagnosed as having severe sepsis which was then observed for their mortality The Spearman correlation tests showed that there was a weak yet significant correlation (p=0.006) between MPV and APACHE II with r (correlation) = 0.314. The MPV values in this study were unable to predict mortality (AUC) ROC 58.2% (95% CI: 45.1–71.2%, p=0.223). whereas the APACHE II score has a moderate ability to predict mortality (AUC) ROC 70,4% (95% CI: 58,6–82,2%, p= 0.002). The cut-off point of APACHE II was 19 with a sensitivity of 65.9% and a specificity of 65.7%, and a PPV of 69.2% and NPV of 62.2%. Therefore, based on this study the MPV score cannot be used as a mortality predictor in severe sepsis patients.Key words: APACHE II score, mean platelet volume, ICU mortality DOI: 10.15851/jap.v4n3.901
Perbandingan Insidensi Post Dural Puncture Headache (PDPH) Pascaseksio Sesarea Dengan Anestesi Spinal Antara Tirah Baring 24 Jam Dengan Mobilisasi Dini Mohamad Andy Prihartono; Ezra Oktaliansah; A. Himendra Wargahadibrata
Jurnal Anestesi Perioperatif Vol 1, No 1 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Post Dural Puncture Headache (PDPH) merupakan salahsatu komplikasi iatrogenik dari anestesi spinal. Patofisiologi PDPH sampai saat ini belum jelas, namun teori yang selama ini dianut akibat penurunan volume dan tekanan CSS (Cairan SerebroSpinal). Penelitian terdahulu menyatakan PDPH dapat dicegah dengan tirah baring selama 24 jam. Beberapa penelitian terbaru membuktikan mobilisasi dini tidak meningkatkan resiko PDPH. Tujuan penelitian ini untuk membuktikan bahwa tidak ada perbedaan insidensi PDPH pada pasien yang dilakukan tirah baring selama 24 jam dengan mobilisasi dini segera setelah fungsi motorik pulih.Penelitian dilakukan dengan tipe quasi experimental dan rancangan rangkaian waktu dengan pembanding. Penelitian melibatkan 200 wanita hamil berumur 18-30 tahun, yang akan dilakukan seksio sesarea dengan anestesi spinal, kemudian dibedakan dalam dua kelompok masing-masing 100 orang. Kelompok pertama dilakukan mobilisasi dini segera setelah fungsi motorik pulih (skala Bromage 1) dan kelompok kedua mobilisasi setelah tirah baring selama 24 jam pascaseksio sesarea. Kemudian, setiap kelompok dilakukan pengamatan terhadap ada atau tidaknya PDPH sampai 2 hari pascaoperasi. Dari hasil penelitian dianalisis dengan uji statistik yaitu uji chi kuadrat dan uji Mann Whitney, di mana nilai p<0,05 dianggap bermakna. Analisis statistik menunjukkan bahwa perbandingan insidensi PDPH pada kelompok yang dilakukan mobilisasi dini (setelah fungsi motorik pulih) dan tirah baring selama 24 jam tidak bermakna (p>0,05). Pada kelompok pertama (mobilisasi dini) 100% tanpa PDPH dan kelompok kedua (tirah baring 24 jam) 99% tanpa PDPH. Simpulan dari penelitian ini adalah tidak didapatkan perbedaan insidensi PDPH pada pasien pascaseksio sesarea dengan anestesi spinal yang dilakukan tirah baring selama 24 jam dengan mobilisasi dini segera setelah fungsi motorik pulih.Kata kunci : mobilisasi dini, Post Dural Puncture Headache, seksio sesarea dengan anestesi spinal, tirah baring 24 jamComparison Of Post Dural Puncture Headache (PDPH) Incidence In Post Caesarean Section Using Spinal Anesthesia Underwent Bed Rest Position For 24 Hours Compared With Early MobilizationPost Dural Puncture Headache (PDPH) is defined as an iatrogenic complication of spinal anesthesia. The pathophysiology of PDPH remains unknown until today, but the referenced theory is due to the decrease of the LCS (Liquor Cerebrospinal) volume and pressure. The early studies confirmed that PDPH was preventable with bed rest position for 24 hour. Numerous current studies have proven that early mobilization does not increase PDPH risks. The objective of this study was to prove that there is no significant difference in PDPH incidence in bed rest patients for 24 hours compared with early mobilization patients as soon as the motoric function has been recovered. The study was conducted using quasi experimental type and control time series design. This study involved 200 pregnant women at the age of 18-30 years that were on Caesarean Section using spinal anesthesia then they were classified into 2 groups with 100 subjects, respectively. The first group was conducted early mobilization as soon as the motoric function has been recovered (using Bromage 1 scale) and the second group was conducted mobilization after bed rest 24 hours post sectio Caesarean. And then, each group was observed for the occurrence of PDPH until 2 days post surgery. The study analysis was assessed using chi square test and Mann Whitney test, which the score of p<0,05 was considered statistically significant value. Statistical analysis showed that the comparison of PDPH incidence in the early mobilization group (after motoric function had been recovered) and the bed rest for 24 hour group was not statistically significant (p>0,05). The first group (early mobilization) showed 100% of the patients without PDPH incidence and the second group (bed rest for 24 hour) showed 99% of the patients without PDPH incidence. The summary of this study revealed that there was no significant difference on PDPH incidence in post Caesarean section patients underwent spinal anesthesia with bed rest for 24 hours compared with early mobilization as soon as the motoric function had been recovered. Key words: Cesarean section with spinal anesthesia, early mobilization, Post Dural Puncture Headache, 24 hours bedrestDOI: 10.15851/jap.v1n1.155

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