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Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Core Subject : Health, Science, Education,
Education Medicine & Pharmacology Neuroscience Public Health
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 906 Documents
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Penatalaksanaan Erisipelas pada Pasien Dewasa Usia 42 Tahun Melalui Pendekatan Dokter Keluarga Vermitia; Reni Zuraida
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.119

Abstract

Erysipelas is a relatively common infectious disease of the skin form of erythema which is clearly demarcated with elevated margins with signs of acute inflammation. The incidence of erysipelas in 2012 in Surabaya was 14 cases with the most cases in women and in the age group 45-64 years. Erysipelas is a disease that can be treated in primary health care facilities or general practice. But there are risk factors for this disease that cause frequent cases of recurrent erysipelas so that proper management is needed. This study is a case report which aims to identify internal and external risk factors and clinical problems in patients, as well as holistically manage patients by applying family doctors according to evidence based medicine through a patient centered approach and family approach. Primary data were obtained through history taking (autoanamnesis from patient and alloanamnesis from patient's family) physical examination and home visits. Secondary data were obtained from the patient's medical record. Assessment is based on a holistic diagnosis from the beginning, process, and end of study in a qualitative and quantitative manner. Patient Mr. W age 42 years old has been diagnosed with erysipelas having concerns about health conditions that are considered to interfere with his work and daily activities. Limitations on the patient's knowledge of the disease (cause, mode of transmission, risk factors, treatment, and complications). In addition, patients pay little attention to personal hygiene, especially related to the risk of hygiene in their work. Holistic and comprehensive management of patients' problems Mr. W has been done by providing counseling to improve patient and family knowledge of erysipelas.
Diabetes Mellitus akibat Anti Psikotik pada Pasien Skizofrenia Danang hafizfadillah; Rasmi Zakiah Oktarlina
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.121

Abstract

Schizophrenia is a mental illness with complex pathophysiology and covers various aspects such as behavioral, nerve, perception, and senses that can affect social life even disfunction at work. Schizophrenia requires a long-term treatment with anti-psychotic. The use of antipsychotics among adults and older has increased. Recent information regarding the use of antipsychotics in schizophrenic patients is associated with risk factors of cardiovascular and metabolic syndrome such as obesity, hypertension, insulin resistance, low HDL levels and high triglyceride levels. Diabetes mellitus is a syndrome of metabolic diseases characterized by chronic hyperglycemia either because the body does not produce enough insulin or because the cells do not respond to the insulin that has been produced. The numbers of type 2 diabetes mellitus is estimated to be two to three times higher in people with schizophrenia than in the general population, with a prevalence of 10% to 15%. The risk of diabetes is caused by antipsychotics which cause chronic effects of weight gain and systemic inflammation that will lead to insulin resistance, the direct effect of antipsychotic drugs on insulin action and drug-induced apoptosis of pancreatic beta cells. This article is a literature study to discuss the effects of using antipsychotic drugs in schizophrenic patients who have a role in the development of diabetes mellitus, direct and indirect effect of antipsychotics on the incidence of diabetes mellitus.
Pengaruh Konsumsi Teh Hijau Terhadap Penurunan Tekanan Darah Pada Pasien Hipertensi Andini Pramesti Ningrum; Winda Trijayanthi Utama; Intanri Kurniati
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.122

Abstract

Hypertension is one of the most common diseases found in primary medical practice. The manifestation of hypertension is a disorder of cardiovascular hemodynamic balance which has an increase in systolic blood pressure ≥ 140 mmHg and or diastolic blood pressure ≥ 90 mmHg which is persistent, on repeated examinations. Hypertension complications can affect various target organs such as the heart, brain, kidneys, eyes, and peripheral arteries. Hypertension is influenced by the role of intravascular volume, the role of autonomic nerve control, and the role of renin angiotensin aldosterone. Tea is thought to have a variety of health benefits and most of the evidence suggests that green tea consumption is associated with lowering blood pressure. Tea and its secondary metabolites, namely polyphenolic compounds called flavonoid, play an important roles in relaxing smooth muscle contraction, enhancing eNOS activity, reducing vascular inflammation, inhibiting rennin and endothelin-1 activity and anti-vascular oxidative stress. Consumption of green tea can significantly reduce systolic blood pressure by 1.98 mmHg and diastolic blood pressure by 1.92 mmHg. The positive effect of green tea on blood pressure was obtained after consuming low doses (<582.8 mg/day) with long-term duration (≥12 weeks). A drop in blood pressure can lower the chance of complications.
Penatalaksanaan Holistik Pasien dengan Asma Persisten Sedang di Wilayah Puskemas Hanura Anggiya Yuliasari; Aila Karyus
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.124

Abstract

Asthma is a chronic inflammatory process of the respiratory tract involving many cells and their elements. This chronic inflammatory process causes the respiratory tract to become hypereponsive, facilitating the occurrence of bronchoconstriction, edema, and gland hypersecretion, resulting in restriction of air flow in the respiratory tract with periodic clinical manifestations of wheezing, shortness of breath, heavy chest, coughing particularly Night or early morning. Applying a holistic and comprehensive approach to the family doctor in detecting internal and external risk factors that solve problems by Evident Based Medicine from family-approached and patient-centered. This study is a case report. The primary data obtained through anamnesis, physical examination and a home visit. Secondary data were obtained from medical records of patients. Mrs. S, 64 years old, complained of shortness since one day ago, followed coughing and wheezing. Obtained internal factors such as genetic factors, lack of knowledge of patients about disease, curative treatment, and never exercising. External factors include lack of hygiene in items at home, cold allergies and lack of support and family knowledge about the patient's illness. Three home visits were made to intervene on patients and families about illnes, prevention, management at home, and the importance of avoiding risk factors. In the evaluation, we found patients began to make improvements but not all of them. This shows that by increasing knowledge, correct treatment and several intervention visits can change the behavior of patients.
Efektivitas Nutrasetikal sebagai Agen Kemopreventif dalam Melawan Sel Kanker Payudara Tesya Agustin; Ratna Dewi Puspita Sari
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.126

Abstract

Cancer is the leading cause of death with breast cancer cases that occupies the highest incidence rate in Indonesia. Breast cancer is a growth of abnormal cells in the epithelium of the ducts or lobules of the breast, causing malignancy in the breast tissue. Beacuse the breast cancer is the most common cancer case, so early detection is carried out and accompanied by recommendations for the most effective treatment for confirmed patients. However, some of these therapies trigger unexpected side effects, then a lot of efforts were made to prevent and control the growth of malignant cells in breast cancer. This malignancy can be inhibited by consuming nutraceutical, which is a combination of nutrition and pharmaceuticals. Nutraceutical is a type of food whose nutritional composition has benefits for health, both prevention and treatment of a disease. The chemopreventive components in fruit and vegetables that are classified as nutritional, besides having effect on health, also having the potential for the anti-carcinogen and anti-mutagenic action. The compounds contained in it are able to against cancer cells with minimal side effects. There are many of them such as ginger, turmeric, cruciferous vegetables, soybeans, tomatoes, garlic, black cumin, and pomegranate have potential anticancer action by reducing the growth of cancer cells, inhibiting cell proliferation, and inducing apoptosis of cancer cells. Thus, nutracetical has potential as a chemopreventive agent with various mechanism of action to against breast cancer cells effectively.
Pengaruh Pemberian Ekstrak Biji Kopi Robusta Lampung (Coffea canephora) terhadap Nilai Elevated Plus Maze (EPM) Kecemasan Tikus Putih Jantan (Rattus novergicus) Galur Sprague dawley yang Diinduksi Monosodium Glutamat (MSG) Adillah Afrilia Syahwina Pado; Anggraeni Janar Wulan; Eca Cania B
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.129

Abstract

Anxiety can be triggered by consuming MSG through the mechanism of oxidative stress. Lampung Robusta coffee bean extract contains polyphenols, given as an antioxidant and neuroprotective. To know the effect of the giving of Lampung Robusta Coffee Bean extract (Caffea canephora) to the value of Elevated Pus Maze (EPM) Anxiety of Male White Rats (Rattus novergicus) Sprague Dawley strain induced by Monosodium Glutamate (MSG). Experimental research with Posttest Only Control Group Design. This study used 25 Sprague Dawley (Rattus norvegicus) male rats randomly selected and divided into 5 groups namely, K1 (negative control), K2 (MSG 2g / kgBB / day), P1 (MSG 2g / kgBB / day + coffee 0.5mg / ml), P2 (MSG2g / kgBB / day + coffee 1mg / ml) and P3 (MSG2g / kgBB / day + coffee 2mg / ml). The mean duration (seconds) on the open arm was K1 78.6 ± 62.9, K2 4.2 ± 9.3, P1 5.0 ± 7.8, P2 10.0 ± 13.6 and P3 14.8 ± 13.5. The mean duration on the closed arm was K1 141.8 ± 105.0, K2 271.2 ± 33.7, P1 285.2 ± 12.9, P2 266.2 ± 32.7 and P3 261.2 ± 15.6 Kruskal-Wallis test on the open arm 0.006 (p <0.05) and 0.026 on the close arm (p <0.05). The Mann-Whitney U test found a significant difference between the K1 and K2 groups and there was no significant difference between the P1, P2, and P3 groups in the open and close arms. There was no effect of giving Lampung Robusta Coffee Bean extract on the value of Elevated Plus Maze (EPM) Anxiety Male White Rats (Rattus novergicus) Sprague dawley strain induced by Monosodium Glutamate (MSG).
Penatalaksanaan Holistik pada Lansia dengan Isolated Systolic Hypertension (ISH), Suspek Retinopati Hipertensi dan Imobilitas: Penatalaksanaan Holistik pada Lansia dengan Isolated Systolic Hypertension (ISH), Suspek Retinopati Hipertensi dan Imobilitas Karimah Khitami Aziz; Dian Isti Angraini
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.130

Abstract

Isolated Systolic Hypertension (ISH) is an increase of systolic blood pressure (BP) without diastolic BP common in old age. ISH may develop from a history of chronic essential hypertension or result from arterial stiffness in normotensive person. Secondary causes of arterial stiffness are type 1 diabetes, osteoporosis with calcification, atherosclerosis, peripheral vascular disease, thyrotoxicosis and aortic disorders. Implementation of family medicine and evidence based medicine by identifying risk factors, clinical problems and management based on a patient centered and family approach. This study is a case report. Primary data were obtained through history taking, physical examination and home visit. The assessment based on the holistic initial diagnosis, process and final diagnosis by in-depth interviews, observation and notes. The patient complained of intermittent headaches and blurred vision since 1 week ago. Complaints for the first time and never been treated. The patient's concern with the complaint interferes with his activities and rest. The patient's expectation of complaints is reduced and not worsen. Patients' perceptions of complaints occur due to certain lifestyles causing diseases that are not known for sure by patient and their family. The patient was diagnosed with grade II ISH. The patient's father had history of hypertension and heart disease. The patient's treatment pattern is curative, rarely has light physical activity, lack of knowledge about the disease, inappropriate diet and eating habits, elderly age and lack of family knowledge about the disease and its complications. Functional degree 2. After the intervention shows clinical improvement and changes in behavior. ISH in the elderly with insufficient knowledge about risk factors, drug use and adherence to BP control can cause acute and advanced complications.
PENATALAKSAAN HOLISTIK PADA PASIEN TINEA KAPITIS MELALUI PENDEKATAN KEDOKTERAN KELUARGA Lantani Nafisah Heviana; Reni Zuraida
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.131

Abstract

Dermatophytosis is a disease cause by the colonization of dermatophyte fungi that attack  keratin-containing tissues such as the stratum corneum of the skin, hair and nails in humans. The prevalence of dermatophytosis in Asia reaches 35,6%.  In Indonesia, dermatophytosis is 52% of all dermatomycoses, which is most are tinea cruris and tinea corporis.  The study was Case Report study.  Primary data is obtained through history taking  and physical examination by making home visit, filling out family folders, and filling in patient files.  Assesment is carried based on the initial holistic diagnosis, process, and end of the visit quantitatively and qualitatively.  Lack of patient knowledge about the disease and poor personal hygiene of patient are the main internal risk factors causing patient to have gray patch type of Tinea capitis.  The intervention that was given is education and counseling  of the patient and patient family about matters that must be modified and the prevention about the disease.  The intervention divided into patient center, family focus and community oriented.  After holistic intervention with educational and counseling methods, there are decrease in clinical symptoms and behavioral changes was obtained by maintaining personal hygiene and the environment
Manifestasi Kulit pada COVID-19; Pengulasan Syifa Rahmi Fadhila; Winda Trijayanthi
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.132

Abstract

COVID-19 is a respiratory infection caused by the coronavirus. The main target of this virus attacks the mucosa of the upper respiratory tract and angiotensin-converting enzyme (ACE2) which is the receptor for viral entry. COVID-19 has many clinical manifestations. The clinical manifestations that appear in COVID-19 patients are similar to other respiratory viral infections, such as high fever, dry cough. However, over time there are many other manifestations such as fever, dry cough, diarrhea, shortness of breath (dyspnea), ageusia, anosmia, and the onset of skin manifestations. This article discusses skin manifestations in COVID-19 patients based on literature studies. The research method used in this journal is literature review. The author is looking for literature related to the topics discussed in this journal. From the research results, the skin can appear within 3 days before being diagnosed up to 13 days after being diagnosed with COVID-19. In the case of positive Covid-19 asymptomatic patients, clinical manifestations will appear on the 14th day and can be used as indicators of diagnosis. The most common skin manifestation that appears in COVID-19 patients is a maculopapular rash. Other lesions that can occur in COVID-19 patients, especially in young adults to the elderly, are urticaria, erythema nodosum, vesicular rash, petechiae / purpuric rash.
Psikobiotik: Peran Mikrobiota Usus Dalam Kesehatan Jiwa Fachry Naufal; Diaru Fauzan Farizy; Winda TU
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.133

Abstract

Inside human body, beneficial microbes reside on or within tissues. Recent studies show that the gut microbiota plays an important role in mental health – they are linked to the brain by the gut-brain axis. The gut-brain axis is a complex neurohumoral communication network and take a role from maintaining the central nervous system function to metabolic homeostasis. Psychobiotic is defined as a living organism which benefits mentally ill patients. Psychobiotics increases neurotransmitter production in the gut, including dopamine (DA), serotonin (5-HT), noradrenaline (NA), and γ-aminobutyric acid (GABA), which modulates neurotransmitters transmission on proximal synapse in enteric nervous system. Researchers conduct studies which makes several strains of psychobiotics consumed as probiotics, as a form of intervention to several types of psychiatric patients, such as patients with anxiety, depression, schizophrenia, autism, Parkinson disease, Alzheimer, to multiple sclerosis. After the duration of the intervention, assessments are done by questionnaires and samples are taken from the patient’s stool. Researchers found that psychobiotics gives therapeutic effects and a positive outcome to mentally ill patients that are seen from elevated mood, improved depression, and improved overall mental health, so it has a potential as an intervention to several mental disorders, aside from pharmacological therapy.

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