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INDONESIA
Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Articles 906 Documents
Uji Aktivitas Antibakteri Ekstrak Kulit Pisang Muli (Musa acuminata) terhadap Methicillin Resistant Staphylococcus aureus Lulu Wilda Nurani; Tri Umiana Soleha; Syahrul Hamidi Nasution
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.229

Abstract

MRSA infection is an urgent global health problem. Synthetic or natural antibacterials should be developed as an effort to overcome the problem. The mauli banana peel contains potential antibacterial compounds such as flavonoids, tannins, saponins, alkaloids, and terpenoids. The purpose of this study is to determine the antibacterial activity of mauli banana peel extract (Musa acuminata) against methicillin resistant Staphylococcus aureus (MRSA). The design of this study was true experimental descriptive, with a post-test control group design. This study examined the antibacterial activity of mauli banana peel extract at concentrations of 100%, 50%, 25%, 12.5%, and 6.25% against MRSA bacteria by measuring inhibitory zone, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC). The results of this study showed that mauli banana extract has antibacterial activity against MRSA with the average diameter of inhibition zone ranging from 23,963 mm to 11,075 mm. The MIC obtained at concentrations of 6.25% and MBC at extract with concentration 50%. One-Way Anova test obtained p value = 0,000 (p <0.05) which means there is a significant difference. Based on the experiment, we can conclude that there is antibacterial activity of mauli banana peel extract (Musa acuminata) against methicillin resistant Staphylococcus aureus (MRSA).
Laporan Kasus Pansitopenia Pada Infeksi Malaria Falsiparum Luh Dina Yulita; Yusuf Aulia Rahman
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.230

Abstract

Malaria is a life-threatening infectious disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes or through blood transfusion. Malaria is an endemic disease that still remains a major health problem in the world. The authors report a case of 21-years old man who presented with intermittent fever and pancytopenia without any signs of spontaneous bleeding that had a history of travel to a malaria endemic area. The diagnosis of malaria is made through examination of peripheral blood morphology. These findings highlights the importance for clinicians to consider tropical malaria diagnosis in patients with acute infection and presented with pancytopenia. Management of this patient included administration of anti-malaria drugs, transfusion of PRC, enteral nutrition, adequate fluids administration, antibiotics in the condition of leukopenia, and administration of other symptomatic therapies. The clinical condition and laboratory findings gradually improved after six days of hospitality.
Hubungan Paritas Dengan Kejadian Ketuban Pecah Dini DI RSUD Abdul Moeloek Periode Maret-Agustus 2017 Aulia Ulfah Raydian; Rodiani
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.231

Abstract

Labor wiith history rupture of the membrane is at high risk for maternal and infant death, which is one of the causes of parity. Parity is one of the factors occurs premature rupture of membranes where maternal women with multiparity tend to be more susceptible to experience premature rupture of membranes. The purpose of this studyto determine the relationship between parity and PROM during inpartu.This research used observational analytic method with cross sectional design. A total sample of 249 patients were selected with consecutive sampling technique. Data collected from patient's medical record in obstetric room of RSUD Dr. H. Abdul Moeloek Lampung Province. The inclusion criteria of this research is mothers with premature rupture of membranes both vaginal delivery and cesarean section. Patients were accompanied by parity data inaccuracies, and damaged medical records were excluded from the study sample.The results showed that as many as 59 patients (23.69%) experienced with rupture of the membrane and as many as 31 (12.44%) patients who experienced rupture of the membrane with multiparity. Based on Chi-square test, p = 0.031 (p <0.05) was obtained. The conclusion of this study that there is relationship between parity with premature rupture membrane in RSUD Dr. H. Abdul Moeloek.
Herpes Zoster Dermatome Nervus C6-C7 Pada Penderita TB-MDR : Laporan Kasus Mitha Miftahul Jannah; Yulisna
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.232

Abstract

Herpes shingles (HZ) is an infectious disease caused by the reactivation of the varicella shingles virus (VVZ). Are localized, mainly attacking adults with a characteristic of radicular pain, unilateral, and a horde of vesicles that are dispersed according to dermatoms that are ineralized by a single sensory nerve ganglion. Factors that potentially lead to reactivation are: previous exposure to VVZ (chickenpox, vaccination), age more than 50 years, Immunocompromais state, immunosuppressive drugs, HIV/AIDS, bone marrow transplantation or organ, violence, therapy Long-term steroids, psychological stress, trauma and the act of Distinction. Incidence of HZ in children 0.74 from 1000 person per year. This incidence increased to 2.5 from 1000 people at age 20-50 (adult age), 7, from 1000 people aged more than 60 years (older adult age) and reached 10 from 1000 person per year at the age of 80. Case: reported case of Mrs. P, 55 yo with a diagnosis of herpes shingles with TB MDR with based on anamnesis and physical examination administered therapy acyclovir tab 5x800 mg PO/day for 7 days, Paracetamol tab 3x500 mg PO/day if necessary, powder salicyl 2% applied on the lesions 3x/day and given the drug TB MDR namely Cycloserin, etionamides and moxifloxacin. Conculsion: The patient showed good therapeutic results.
Penatalaksanaan Holistik pada Lansia dengan Stroke Disertai Ulkus Dekubitus dan Hiperkolesterolemia Melalui Pendekatan Kedokteran Keluarga Natasha Naomi Harli Putri; Diana Mayasari
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.233

Abstract

Stroke is the second leading cause of death and the third cause of disability in the world. Globally, 87% of strokes related to death and disability occur in low-medium income countries. Recovery from a stroke depends on many factors including the risk, the accuracy and speed of management, the disease that aggravates stroke and treatment and the implementation of early mobilization to prevent one complication of prolonged bed rest. Things to consider in handling post-stroke patients is family support. Family support can support patient recovery and recovery. The study conducted was a case report. Primary data was obtained through history taking and physical examination by making home visits. The assessment was carried out based on a qualitative initial holistic diagnosis, process, and end of visit. Based on the examination, the patient was a 62-year-old woman diagnosed with stroke, pressure sores, hypercholesterolemia, history of hypertension, and nucleus pulposus hernias. Very limited patient knowledge about the disease is evident from patients and family who have never been controlled or treated. Education and intervention are given to patients and families about stroke and its relationship with hypercholesterolemia and a history of hypertension, its complications in the form of pressure ulcers, hernia nucleus pulposus suffered by the patient and its treatment in 3 home visits. In the evaluation found an increase in patient compliance to avoid risk factors and family knowledge about patient care. Unhealthy lifestyles and lack of knowledge of patients about the disease become risk factors for the occurrence of disease in patients. Services with a family medicine approach in pharmacological and non-pharmacological therapy are able to solve health problems and improve the quality of life of patients.
Penatalaksanaan Holistik Pada Pasien Hipertensi Dan Obesitas Derajat II Dengan Riwayat Stroke Melalui Pendekatan Kedokteran Keluarga Tania Matalauta Sitepu; Diana Mayasari
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.234

Abstract

Hypertension is one of the non-infectious diseases which becomes an important health problem throughout the world because it keeps increasing. There are 9.4 million deathhs from cardiovascular disease are caused by complications of hypertention. Hypertension itself is a multifactorial disease that arises mainly because of interactions between certain risk factors that can be modified or cannot be modified. Whereas, obesity is caused by an imbalance between the incoming energy and the energy that comes out. The prevalence of obesity throughout the world has tendency to increase in past 30 years.. In addition, Farmingham study stated that 65% of women and 78% of men who suffer from hypertension are directly related to weight gain and obesity. The study was Case Report Study. Primary data is obtained through history taking and physical examination by making home visits, filling out family folders, and filling in patient files. Assessment is carried out based on the initial holistic diagnosis, process, and end of the visit quantitatively and qualitatively. Based on a holistic diagnosis, the patient has a complaint of feeling headache and often followed by a feeling of heaviness behind the neck. The patient also had a history of stroke four years ago. Patient feel worried that the disease is getting worse, has recurrent stroke, and be a burdensome for his family. The patient's expectation is less clinical symptoms , controlled hypertension, no longer obesity, and can do activity and work normally again. Patient was diagnosed with hypertension and obesity in grade II based on the results of history and physical examination. The patient is a 53-year-old man who is obese, often eating foods that contain lots of salt, oily food, and lack of physical activity. Patients are less aware of the disease and the right lifestyle for the illness. After the intervention is done holistically with drugs and education, he obtains a decrease in clinical symptoms and behavioral changes by changing lifestyle and routine taking drugs. Diagnosis and management of this patient has been doing holistically, patients center, family approach based on several theories and current research. In the process of behavior change, patient has reached the trial stage.
Endoftalmitis Et Causa Ulkus Kornea dan Glaukoma Sekunder dengan Penyakit Mata Tiroid di Bidang Agromedicine Rosy Osiana; Rani Himayani; Helmi Ismunandar
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.235

Abstract

Thyroid Eye Disease (TED) is a disease of the eye that is characterized by bilateral proptosis which is added by increasing levels of T3, T4 and increasing TSH levels. TED patients are common exposure to keratitis in the cornea that is not properly closed and not completely closed by the palpebra. Corneal ulcers can occur due to keratitis. TED patients can also be approved with glaucoma. 31-year-old man who came with the main complaint that refused perfect vision since 2 weeks of SMRS. The initial complaint of the patient was raised casually for the second time since 3 weeks of SMRS. The patient has a view about the use leaf extract of the right eye so that make red eye and vision decrease increasingly then left eye and enlarge white spots. In patients complaining of weight loss of 14 kg for 1 month released with weakness, nausea, sweating, and shaking compilation in resting conditions. At the time of physical examination found a general situation, the level of compost mentis awareness, blood pressure 140/100 mmhg, pulse 130 x / min. The results of physical examination on the eyes obtained sharp vision of VOD 1/300 and VOS 6/60, exoftamus (+) ODS, ciliary injection (+) OD, conjunctival injection (+) ODS, corneal edema (+) OD, cumhipopion (+ ) OD size 2 mm x 1 mm, shallow anterio OD occer camera, and ODS secret (+). Laboratory examination T3 and T4 increased and TSH decreased. Treatment involves education, antibiotik, antihistamin, kalium, beta blocker, antifungal, diuretic, and steroid.
Psoriasis Pustulosa Generalisata: Tinjauan Kasus Pada Geriatri Febe Sintia Kristiani; Dwi Indria Anggraini
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.236

Abstract

Psoriasis is a chronic disease of the skin that is characterized by accelerated epidermal exchange and a faster keratinization process. Psoriasis has a variety of manifestations, one of which is generalized pustular psoriasis characterized as pustular sterile eruption. This case report aims to determine the diagnosis and management of generalized pustular psoriasis. Case, a 75-year-old woman complained of the emergence of pustule throughout the body since four days ago accompanied by burning and itching sensation. Some pustule confluence make a lake form (lake of pus), and some lesion consist of erythematous plaque with yellowish greasy scale. The patient has a history of hypertension, use of pain killer, and sudden stopping steroids. Based on history taking, physical examination and laboratory, the diagnosis of generalized pustular psoriasis is made. The treatment given was in the form of corticosteroid methylprednisolone intravenous injection 31,25 mg/ 12 hours, ranitidine intravenous injection 50 mg/12 hours, cetirizine peroral 1x10 mg, betametason valerate cream 0.1% in urea 10% cream.
Manajemen Neurogenic Pulmonary Edema pada Laki-laki Usia 60 Tahun dengan Stroke Infark Luas di RSUD Jendral A. Yani Kota Metro M. Panji Bintang Gumantara; Halomoan Simon Tambunan
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.237

Abstract

Neurogenic Pulmonary Edema (NPE) is a pulmonary compromise condition due to severe damage of the central nervous system that causes symptoms similar to ARDS accompanied by pulmonary edema. NPE often occurs in traumatic brain injury (TBI), hemorrhage, recurrent seizures, and epilepsy. Stroke is a focal or general acute neurological deficit condition during more than 24 hours caused by cerebrovascular factors. In patient with extensive stroke infarction of the brain can cause suppression of the respiratory center in the brain so that stroke patients can get complications in the respiratory system that aggravate the patient's condition. This case report described a 60-year-old man with decreased consciousness and weakness of the left limbs since 6 hours before entering hospital with shortness of breath, reddish coughing phlegm, fever, rapid and shallow breathing. Management was given to the patient in pharmacological and non-pharmacological collaborative therapies. Intensive care was planned in the Intensive Care Unit (ICU) formechanical ventilator. The patient's prognosis in this case report wasad malam. The purpose of this case report is to find out the description of clinical problems, identify the risk factors as the cause and provide the best management for patients.
Sindrom Obstructive Sleep Apnea William Bahagia; Putu Ristyaning Ayu
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.238

Abstract

Obstructive Sleep Apnea (OSA) is a disorder and part of a complex sleep disorder breathing syndrome. OSA symptoms often occur althought it difficults to detect. If OSA does not get good management, it will cause long-term health problems. OSA is a condition of periodic upper airway obstruction during sleep that causes the breath to stop intermittently, either completely (apnea) or partial (hypoapnea). This condition is occurring in the upper respiratory tract (mainly in the oropharynx) resulting in decreased air flow. OSA symptoms are classified into night symptoms and daytime symptoms. Recurrent episodes of apnea, intermittent hypoxia and sleep fragmentation may affect organ function, especially the central nervous system and cardiovascular system, resulting in changes in metabolic balance. The gold standard for diagnosis of OSA is through a night sleep check with Polysomnography / PSG). The index used to determine the degree of mild-bad OSA is the Apnea-Hypoapnea Index (AHI), which counts the number of obstructive events per hour during sleep and the results of cardiorespiratory monitoring. Management of OSA consists of surgical therapy and non-surgical therapy. Positive airway pressure (PAP) is known to be the gold standard therapy for OSA. This article is a literature study to discuss pathophysiology, risk factors, signs and symptoms, to the handling and prevention of OSA.