cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota surakarta,
Jawa tengah
INDONESIA
Jurnal Kedokteran Indonesia
Published by Universitas Sebelas Maret
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 11 Documents
 1   2 
Search results for , issue " Vol 3, No 1 (2012)" : 11 Documents clear
Hubungan antara Pemakaian Repellent Anti Nyamuk dan Kejadian Penyakit Demam Berdarah Dengue pada Anak di Kota Surakarta Sofia, Fika Khulma; Probandari, Ari Natalia; Hikmayani, Nur Hafidha
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Dengue haemorrhagicfever (DHF) is a common mosquito-transmitted infectious disease in tropical and sub​​-tropical areas. In Indonesia, the incidence significantly increased from 58 cases in 1968 to 15,912 cases in 2009. Case fatality ratereached over 1% in most provinces. Repellent refers totopical antimosquito agent which can be used to prevent DHF. Repellent contains active substances that prevent mosquito bites such as DEET (N,N‑dietil‑m‑toluamid) and permethrine. This study aimed to examine the relationship between use of anti-mosquito repellent and risk of DHF among children in Surakarta. Method: This was an observational study using matched case-control design. It was carried out atfive public health centers in Surakarta with high prevalence of DHF in children during 2010-2012period. Forty cases were selected using cluster sampling method and were matched for age and residence with 40 DHF-free controls. Questionnaires were used to identify use of repellent. Other data collected included frequency, habit,timing and duration of repellent use. Data were analyzed by McNemar’s χ2test and conditional logistic regressionsusing OpenEpi 2.0 and Stata SE 12.0. Results: McNemar’s χ2 test showed a significant relationship between use of antimosquito repellent and DHF (p<0.001). Children usingantimosquito repellent had 0.04 times the risk for DHF than those not using repellent (OR=0.04, 95%CI= 0.01 to 0.23). Regression analysis showed that frequency and timing of repellent use were significantly associated with DHF. Compared to children who did not use repellent, children using repellent often (5-7 times a week) had0.12 times the risk for DHF (OR=0.12,95%CI=0.02 to 0.60; p=0.011).Children using repellent after 8 pm had0.22 times the risk for DHF (OR=0.22, 95% CI=0.01 to 0.70; p=0.022). Habit and duration of repellent use showed no statistically significant association with DHF (p>0.05). Conclusion: Use of repellentsignificantly reduces the risk for DHF among children in Surakarta. Frequent and nocturnal useofrepellentare protective factors for DHF.Keywords: Dengue haemorrhagic fever, antimosquito repellent, children
Aktivitas Antimikroba Fraksi-Fraksi Dari Ekstrak Jamur Endofit Cladosporium oxysporum Yang Diisolasi Dari Aglaia Odorata Lour Sugijanto, Noor Erma; Dorra, Bella Lexmita
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background:Some endophytic fungi have shown economicpotentials for future  production of enzyme, medicine, and biological control agent. This study aimed to examine the antimicrobial activities in ethyl acetate extract fractions of Cladosporiumoxysporumendophyticfungi against Escherichia coli, Staphylocooccusaureus,and Candida albicans. Method: Cladosporiumoxysporumendophyticfungi  was isolated from AglaiaodorataLour (pacarCina, Java)which was collected at Purwodadi Botanical Garden, Pasuruan, East Java. C. oxysporum were cultivated, extracted and fractionated. The fractions then were applied to antimicrobial activity assay. Disc diffusion method was conducted with 2 mg/disc concentration extracts. Results: The ethyl acetate extract fractions of C.oxysporumshowed antimicrobial activities against the three microbes tested. Six of 13 fractions exhibited inhibition zone against S. aureus ATCC 6538, E. coli ATCC 8739 and C. albicans ATCC 10231. The seventh fraction exhibited the highest inhibition zone against S. aureus ATCC 6538, and C.albicans ATCC 10231. The tenth fraction exhibited the highest inhibition zone against E. coli ATCC 8739. Conclusion:Cladosporiumoxysporum from Aglaiaodoratais a good source of antimicrobial substance.The discovery of bioactive metabolites in C.oxysporumendophytic fungi allows the development of a new antimicrobial medicine for commercial use. Key words:Cladosporiumoxysporum,endophytic fungi, AglaiaodorataLour,antimicrobial activity
Skrining Risiko Kardiovaskular Pada Dosen dan Staf Administrasi Fakultas Kesehatan Masyarakat Universitas Jember Prasetyowati, Irma; Ariyanto, Yunus; Wahjudi, Pudjo
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background:Cardiovascular disease is the leading cause of death and disability worldwide. An effort to prevent mortality from cardiovascular disease is to detect the disease early at the subclinical stage. This study aimed to screen lecturers and administration staff at the Faculty of Public Health, University of Jember, for  cardiovascular disease risk factors, and provide necessary advise. Method:A survey was conducted at the Faculty of Public Health, University of Jember, to screen 60 lecturers and administrative staff for cardiovascular diseases risk factors.The risk factors under study included age, blood pressure, body mass index, smoking, exercise, and history of diabetes. Instruments used in this study included questionnaire, sphygmo-manometer, microtoise height scale, bathroom weight scale, waist and hip scale tape. Results: The majority of the lecturers (77.8%) and the administration staff (60.6%) were at low risk for cardiovascular disease. However, about 13.3% of the study subjects had hypertension. Thirty percent were current smokers. About 3.3% had diabetes history. Twenty five percent were overweight, and 18.3% were obese. Conclusion: A few staff at the Faculty of Public health, University of Jember, werefound to be at high risk for cardiovascular diseases. These individuals were advised to adopt healthier life styles, which include exercise, cycling, quit smoking, and regular check-up every 6 months. Keywords: cardiovascular disease, risk factors, screening, healthy life style
Hubungan Pemakaian Alat Kontrasepsi Dalam Rahim dengan Kejadian Kehamilan Ektopik Ayu, Rosalina Pradana; Darto, ; Murti, Bhisma
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background:Ectopic pregnancy is a problem in gynecologic area that causes high maternal morbidity and mortality. Use of intrauterine device (IUD) is a hypothetic risk factor forectopic pregnancy. Progesterone content in the IUD can increase tubal implantation. Changes in theendometrium condition, leukocyte infiltration in the uterus, and  accumulation of macrophages induced by IUD can cause extrauterine pregnancy when ovulation occurs. This study aimed to determine the relationship between IUD use and the risk for ectopic pregnancy, controlling for the effect of age. Methods:This study was analytic observational using case-control design. Thirty patients with ectopic pregnancy sampled by fixed disease sampling were compared with 60 patients with normal pregnancy at the Dr. Moewardi Hospital Surakarta. The data were collected from the medical records, then were analyzed for the relationship using multiple logistic regression model on SPSS 17 for Windows. Results:Women who used IUD had 9.33 times higher risk of ectopic pregnancy than women who did not use IUD (OR= 9.33; CI95%= 1.01 to 86.36; p = 0.049). The analysis has controlled for age as a confounding factor. Conclusion:There is relationship between IUD use and the risk for ectopic pregnancy, after controlling for age. Keywords:Intra-uterine device (IUD), ectopic pregnancy.
Pengaruh Dukungan Keluarga Dan Paritas Terhadap Kecemasan Ibu Hamil Trimester III Dalam Menghadapi Persalinan Di Rumah Bersalin Harapan Bunda Surakarta Susilowati, Dewi; Suryani, Nunuk; Murti, Bhisma
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Pregnancy yields happiness to pregnant women and their husbands. But it can worry them. The support of family gives pregnant women composure, secure feeling, and comfort thereby reducing pregnant woman’s anxiety. This study aimed to determine the effect of family support and parity on anxiety level among third trimester pregnant women in dealing with delivery. Methods:This analytical observational study usedcross sectional design. The reference population was third trimester pregnant women visiting HarapanBunda Maternal Clinic, Surakarta, from June to July 2012. The independent variableswere family support and parity. The dependent variable was anxiety. The data were analyzed using multiple linear regression model. Results:There were statistically significant effects of family support (b = -0.48; p = 0.017) and parity (b = -3.40; p = 0.007) on pregnant women’s anxiety in dealing with delivery. Conclusion:Family support and parity reduce anxiety among pregnant women of trimester pregnancy. The stronger the family support the lower is the anxiety of pregnant women. Multipara, on the average, had lower anxiety than primipara. Key words: Anxiety, family support, parity, pregnant woman
Hubungan Antara Pengetahuan, Sikap Pasien, Dan Dukungan Keluarga Dengan Keteraturan Pengobatan Pasien Tuberkulosis Paru Di Kabupaten Klaten Erawati, Lely; Suryani, Nunuk; Murti, Bhisma
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background : Regularity of pulmonary tuberculosis treatment are affected by many factors such as knowledge, attitudes of patients, and family support.This study aimed to analyze the relationship between knowledge, attitudes of patient, andfamily support, and regularity of tuberculosis treatment. Methods : This was an analytic observational study using a cross sectionaldesign.A sample of 57 pulmonary tuberculosis patients who had been undertaking anti-tuberculosis direct observed treatment short course in Klatendistrict, Central Java, for the past two years were studied. The data on the independent variables including knowledge, patient attitude, and family support, were collected using questionnaire. The secondary data on regularity of tuberculosis treatment were taken from the reporting and recording system at health center and district health office. The relationshipbetween knowledge, patient attitude,and family support and regularity of treatment were analyzed using multiple logistic regression model. Odds Ratio and its 95CI% were estimated. Results : Tuberculosis patientswho had high tuberculosis knowledge had four timeshigher probability to undertake regular treatment than those with low knowledge(OR =4.40 ; CI 95 % = 1.08 to 17.89 ; p = 0.030). Patients with good attitude had three timeshigherprobability to undertake regular treatment than those with poor attitude (OR = 3.67 ; CI95 % = 1.02 to 13.42 ; p = 0.043). Patients with strong family support were twice more likely to undertake regular treatment than those with weak family support (OR = 2.22; CI 95 % = 0.54 to 9.14; p = 0.261). Conclusion: There is a positive relationship between knowledge, patient attitude, and  family support, and regularity of pulmonary tuberculosis treatment. Keywords: Pulmonary tuberculosis, knowledge, patient attitude, family support, regular treatment
Penambahan Dexmedetomidine Memperpanjang Lama Kerja Anestesi Blok Aksilaris Osi, ; Sudjito, Hadi; Murti, Bhisma
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background:Dexmedetomidine is alpha 2 adrenergic receptor agonist that produces analgesia by suppressing norepinephrin secretion and blocking nerve action potential in alpha 2 receptor. This study aimed to determine if addition of dexmedetomidineof  25 µg  dexmedetomidine into 30 mL bupivacaine 0.25% shortens onset and prolongs duration of axillary block anesthesia. Methods: This phase III clinical study used double blinded randomized controlled trial design. A sample of 22 adult patients of ASA I and II were scheduled for lower arm surgery with axillary block. Patients were randomized into 2 groups. Patients in group B ( n = 11) were given 30 mL bupivacaine 0.25% and normal saline. Patients in group D (n = 11) were given 30 mL bupivacaine 0.25% and dexmedetomidine 25 µg. Results: The onset of sensory (p=0.765) and motor (p=0.748) blockade was not significantly different. But, the duration of sensory (p<0.001) and motor (p<0.001) blockade was significantly longer in group D than group B. The side effect of dexmedetomidine administration is bradycardia. Conclusion: The addition of 25 µg dexmedetomidine into 30 mL bupivacaine 0.25%does not shorten onset, but prolongs duration of sensory as well as motor blockade in axillary block anesthesia. Keywords: Dexmedetomidine, bupivacaine, axillary block, onset of sensory and motor blockade, duration of sensory and motor blockade.
Efikasi Premedikasi Klonidin dan Diazepam Peroral Terhadap Level Sedasi dan Respons Hemodinamik Pediatrik Yudha, Sandhi; Santoso, Sugeng Budi; Murti, Bhisma
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Anxiety and pain cause emotional stress in pediatric patients. The right choice of per oral premedication is essential to achieve adequate level of sedation and hemodynamic stability during anesthesia and surgery for pediatric patients. This study aimed to compare the relative efficacy of per oral clonidine and diazepam premedication on the sedation level and hemodynamic response in pediatric patients. Methods: This was a phase II clinical trial, using double blinded randomized controlled trial design. A sample of 18 pediatric patients aged 2-12 years with ASA I and II physical status were divided at random into 2 groups, each group received either per oral clonidine premedication 4μg/kgBW (n=9) or diazepam 0.2mg/kgBW (n=9). Sedation level and hemodynamic response (heart rate) were measured before drug administration (HR1), after drug administration (HR2), before intubation laryngoscopy (HR3), third (HR4) and five minutes after (HR5) treatment before laryngoscopy intubation, immediately after skin incision started. Results: Sedation level in clonidine group (3.11 ± 0.60) was deeper than diazepam group (2.33 ± 0.50) with p=0.013. Heart rate after per oral premedication (HR1) among clonidine group was lower (100.44 ± 11.38 times/minute) than diazepam group (110.22 ± 12.29 times/minute) with p=0.099. Heart rate at time HR2, HR3, HR4, and HR 5among clonidine group was lower than diazepam group at p<0.05. Bradycardia effect was found in 2 patients in the clonidine group but none in the diazepam group. Conclusion: Per oral 4μg/kgBWclonidine premedication leads to deeper sedation level than 0.2mg/kgBWdiazepam. The hemodynamic response (heart rate) was more stable in the clonidine group than diazepam group. Keywords: Per oral premedication, clonidine, diazepam, sedation level, hemodynamic response, pediatrics
Pengaruh Pemberian Propofol Intravena 10mg/KgBB, 25 mg/KgBB dan 50 mg/KgBB Terhadap Ekspresi Kaspase 3 Hipokampus pada Mencit Balb/ C Dengan Cedera Kepala Yusriyani, ; Sudjito, Mulyo Hadi; Murti, Bhisma
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background:Head injury is one of the leading causes of death and disability. In head injury there is biomolecularand biochemical pathologic process that can cause necrosis and apoptosis via caspase 3 activation. Propofol is an intravenous anesthetic drug that has neuroprotective mechanism by regulating caspase 3. This study aimed to determine the inhibitory effect of intravenous propofol 10 mg/kgBW, 25 mg/kgBW and 50 mg/kgBW oncaspase 3expression in mice balb/c with head injury. Methods: This was a laboratory experiment using randomized controlled trial design. Asample of 32 Balb/c mices were divided into 4 groups. All groups underwent head injury procedure using weight drop technique. Group 1 did not received propofol. Group 2, 3, and 4 received intravenous 10 mg, 25 mg, and 50 mg/kgBB propofol, respectively. Caspase 3 activation was stained and identified by immunohistochemical technique 6 hours afteradministration of propofol. Difference in mean between groups was tested by One Way Anova and mean pair-wise groups by Post Hoc Test on SPSS 12. Results: Mean caspase 3 expresion in each group was as follow: Group 1=4.08, Group 2= 2.95, Group 3= 2.52, Group 4=1.77. One way Anova showed statistically significant difference in mean caspase 3 expression between groups (p<0.001). The higher dose of propofol, the lower caspase 3. The pair-wise mean difference were as followsGroup1-Group2 (p<0.001), Group1-Group3 (p<0.001), Group1-Group4 (p<0.001), Group2-Group4 (p<0.001), Group3-Group4 (p<0.001), and Group2-Group3 (p=0.232). Conclusion:Administration of intravenous propofol with 10,25,50 mg/kgBW doses were effective to inhibit caspase 3 activity expression in mices with head injury. Higher doses give stronger inhibitory effect, with 50mg/kgBW being the recommended optimal dose. Keywords: caspase 3 expression, propofol, mice, head injury
Pengaruh Suplementasi Vitamin C, Vitamin E, dan Kombinasinya Terhadap Penurunan Kadar Low Density Lipoprotein Serum pada Pasien Penyakit Ginjal Kronis Stadium V yang Dilakukan Hemodialisis Dewi, Ayu Kusuma; Purwanto, Bambang; Wiboworini, Budiyanti
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background:Low density lipoprotein (LDL) cholesterol is a prognostic factor for hemodialysis mortality through atherosclerosis mechanism. Vitamin C and E have been well known as anti-oxidants that reduced LDL cholesterol. However, there were no studies have been done to address the effectiveness of vitamin C, E, and its combination on lowering LDL in patients with hemodialysis. This study aimed to determine the effect of vitamin C, E, and C and E combination on LDL cholesterol. Methods:A randomized controlled trial was conducted in 64 patients receiving hemodialysis at RSUD Dr.Moewardi(RSDM) Surakarta. The sample was taken at random and then divided into 4 groups: placebo, vitamin C (500 mg), vitamin E (400 mg), and vitamin C + E combination. The treatment lasted for 30 days. LDL cholesterol before and after treatment were analyzed at the Clinical Pathology division, RSDM. The reduction in LDL cholesterol before and after treatment was analyzed using One Way Anovaand (pair-wise) Post-Hoc Test. Results:One Way Anovashowed statistically significant reduction in LDL cholesterol between groups (p<0.001). Post hoc testshowed that vitamin C, vitamin E, or its combination reduced LDL cholesterol more than the placebo (p<0.001). Vitamin C and E administered in combination led to statistically significant lower LDL cholesterol than administered alone (p=0.002). There was no statistically difference in LDL cholesterol level between those provided with vitamin C and vitamin E. Conclusion: Vitamin C and E, individually or in combination, reduces LDL cholesterol. The highest reduction was achieved by vitamin C and E combination.Keywords: vitamin C, vitamin E, LDL cholesterol

Page 1 of 2 | Total Record : 11

 1   2 

Filter by Year

2012 2012


Reset
Filter By Issues
All Issue Vol 3, No 1 (2012) Vol 2, No 1 (2011) Vol 1, No 2 (2009) Vol 1, No 1 (2009)