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Nexus Kedokteran Klinik
Published by Universitas Sebelas Maret
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 334 Documents
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Hubungan antara Kecemasan dengan Frekuensi Bangkitan pada Penderita Epilepsi Parsial di RSUD Dr. Moewardi Lucia Pancani Anggraeni; Diah Kurnia Mirawati; Endang Sutisna Sulaeman
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Anxiety is a psychological disorder that involves dysregulation of the nervous system Therefore, anxiety could affected seizures threshold in people with epilepsy indirectly. The aim of this study was to know an association between anxiety and seizure frequency of partial epileptic patients in hospitals Dr. Moewardi. Methods: This was an observational study with analytic cross sectional approach. Samples were taken by purposive sampling after selected based on inclusion and exclusion criteria. The data were obtained by using of TMAS anxiety scale, interviewed seizures frequency in last one month, and the patient's medical record. Analysis of anxiety and seizures frequencys score used linear regression models by SPSS 17.0 for windows Results: There were 31 samples consisted of 10 women and 21 men. Result showed a significant positive relation between anxiety and seizure frequency of partial epileptic patients in hospitals Dr. Moewardi (p < 0.05, CI 95% = 0.06 - 0.037). Linear regression analysis test showed an equation that Y= a + bX = -1.174 + 0.218 X. It meaned that the seizure frequency would rise -1.174 + 0.218 X unit for every inrcreasing of anxiety level. Conclusion: Patients with higher level of anxiety have had more often seizure attack. Keywords: Partial epileptic patients, anxiety, frequency of seizure
The Difference of Intraocular Pressure (IOP) between Myopic Eyes and Emmetropic Eyes in Medical Students of Sebelas Maret University Putri Nur Kumalasari; Raharjo Kuntoyo; . Widardo
Nexus Kedokteran Klinik Vol 5, No 2 (2016): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Introduction: Intraocular pressure (IOP) is a major risk factor of glaucoma. Prevalence of glaucoma increases in myopic eyes than in emmetropic eyes. There was a hypothesis that the relationship between glaucoma and myopia might be mediated by intraocular pressure. This study aims to investigate the difference of intraocular pressure (IOP) between myopic eyes and emmetropic eyes in medical students of Sebelas Maret University. Methods: This study applied analytical observational method with cross sectional approach. Subject of the research was medical students of Sebelas Maret University batch of 2012. Samples were selected by a screening with inclusion and exclusion criterias and then randomized by simple random sampling technique. The total samples were 76 students. Afterwards, samples were interviewed about last refraction examination history and examined for refraction status through visus examination using snellen optotype so that samples were divided to myopic eyes group and emmetropic eyes group. Then, IOP was evaluated using Non Contact Tonometer (NCT). The data was analyzed with independent t-test which was processed by Statistical Product and Service Solutions (SPSS) 20.0 programme for Windows. Results: The mean of IOP in myopic eyes was 17.02 2.69 mmHg in right eyes (OD) and 16.80 2.84 mmHg in left eyes (OS). The mean of IOP in emmetropic eyes was 15.88 2.44 mmHg (OD) and 15,32 2,34 mmHg (OS). The comparative analysis of IOP between myopia and emmetropia showed the value of p = 0.065 (OD) and p = 0.076 (OS). Conclusions: There is no significant difference of IOP between myopic eyes and emmetropic eyes in medical students of Sebelas Maret University. Keywords: Emmetropia, Intraocular Pressure, Medical Student, Myopia.
Hubungan Antara Kadar Feritin Dengan Kadar ALT dan AST Pada Pasien Thalasemia di RSUD Dr. Moewardi Valentina Lakhsmi Prabandari; Muhammad Riza; Lilik Wijayanti
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Thalassemia major patients need a regular blood transfusion that may cause an iron overload and vital organ dysfunction. This was an observational analytic study to analyze the relationship between ferritin level and transaminase enzymes level in thalassemia patients at Dr.Moewardi General Hospital. A positive relation may remind doctor to pay attention of liver function in thalassemia major patients. Methods: The research was an observational analytic study with cross sectional approach during April-June 2013 in Dr. Moewardi General Hospital. The samples was taken using exhaustive sampling and all were children with beta thalasemia major. These patients had a regular blood transfusion, high ferritin level (>1000 ng/l) and iron chelating agents usage. Ferritin level as independent variable was measured with ELFA method. Transaminase enzymes as dependent variables were measured with IFCC method. These variables were analyzed with Pearson correlation, diagnostic odds ratio and linier regression. Results: Thirty thalassemia patients test results of ferritin, ALT and AST level were collected. Eighteen patients had a very high ferritin level (?3000 ng/l) and the other twelve patients ferritin level were between 1000-3000 ng/l. Eighteen patients had a high ALT level and seventeen patients had a high AST level. Pearson analysis showed a significant result between ferritin and ALT level (p=0.043) also between ferritin and AST level (p=0.028). Pearson correlation strengths were moderate (0.373 and 0.401). Odds ratio between ferritin level with ALT and AST level were 3.333 and 3.111. Conclusions: There was a positively moderate correlation between ferritin level and both ALT and AST level in thalassemia patients in Dr. Moewardi General Hospital. Odds ratio analysis showed that ferritin level above 3000 ng/l is a risk factor of ALT and AST level elevation. Keywords: Thalassemia, iron overload, ferritin, transaminase
Perbedaan Tingkat Depresi Saat Menjalani Pembinaan Intra Mural dengan Saat Menjalani Pembimbingan pada Warga Binaan Pemasyarakatan Elga Putri Indanarta; Mohammad Fanani; Lilik Wijayanti
Nexus Kedokteran Klinik Vol 3, No 2 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Correctional coached people, both in intra mural and in parole coaching are vulnerable to get depression. Depression is a syndrom of depressed mood with sympthoms and signs of pathologic sadness and suffering components. This study aimed to proof the difference of depression levels between inmates who are in intra mural coaching and correctional clients who are in parole coaching that inmates are higher than correctional clients. Methods: This analytic study was observational with cross-sectional approach. 20 inmates who are in intra mural coaching at Class I Detention Center Surakarta (group 1) and 10 ex-inmates who had intra mural coached in Class I Detention Center Surakarta that now under parole coaching as correctional clients by Class II Correctional Center Surakarta (group 2) were taken as samples by total sampling from available population. The primary data were collected by questionnaire of Beck Depression Inventory that answered by the respondens after received some instructions. The data were analyzed using t test on Statistical Package for the Social Sciences (SPSS) version 16.0 for Windows. Results: Group 1 had depression score (meandeviation standart) 23.857.13 and group 2 had 13.107.25. t test showed that depression levels of those groups were significantly different with p=0.002 (p<0.05). Conclusion: There is a statistically significant difference between depression level on inmates who are in intra mural coaching and on clients who are in parole coaching under the supervision of correctional system. Inmates who are in intra mural coaching had higher level of depression than ex-inmates who are in parole coaching as correctional clients. Keywords: depression, inmates, clients, correctional coached people
Hubungan antara Hipoglikemi dengan Kejadian Hipotermi pada Neonatus Rujukan di RSUD Dr. Moewardi Dio Dara Virgiansari; Dwi Hidayah; Leli Saptawati
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Neonatal hypoglycaemia is an avoidable cause of mortality and neurodevelopmental impairment. Hypoglicemia may develop to hypothermia as a result of metabolic thermogenesis disturbance. Hypothermia during the newborns period is widely regarded as a major contributory cause of significant morbidity and mortality in developing countries including Indonesia, about 7% prevalence of hypothermia has been reported happens on newborns. The objective of this study was to determine the association between hypoglicemia and hypotermia in newborns. An analytic observational using cross sectional approach was used in this study. A total of eighty one newborns was selected by fixed-disease sampling. Sample of this study were the newborns who referred to Dr. Moewardi Hospital. The data were collected by the measurement of blood glucose concentration and axillary temperature of newborns. The data was analyzed using multiple logistic regression test on SPSS 16 for Windows. Hypoglycemic newborns have a risk of hypothermia 2.381 times higher than non hypoglicemic newborns after controlling some confounding factors, such as: age, birth weight, gestational age, and status of asphyxia, altough it was statistically not significant (OR = 1.98; CI = 95%; 0.54, 7.73; p = 0.305). Early neonatal age (0-7 days), low birth weight (< 2.500 gram), early gestational age (< 37 weeks), asphyxia status were also risk factors of hypothermia in newborns. There was a moderate association between hypoglicemia and hypothermia on referral newborns, altough it was statistically not significant. Hypoglycemic newborns have a higher risk of hypothermia than non hypoglicemic newborns after controlling some confounding factors, such as: age, birth weight, gestational age, and status of asphyxia. Keywords: newborns, referral, hypoglicemia, hypothermia
The Correlation between Glycemic Control (HbA1c) and Nephropathy Diabetic among Type 2 Diabetes Mellitus Patients in Dr. Moewardi General Hospital Surakarta Emma Ayu Lirani; Dian Ariningrum; Yulia Sari
Nexus Kedokteran Klinik Vol 5, No 1 (2016): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Nephropathy diabetic is the one of the most serious long-term complications of diabetes mellitus which could lead to end stage renal disease. One of the factors that influences nephropathy diabetic is glycemic control that can be monitored trough HbA1c level. The uncontrolled HbA1c level can causes an increasing of end glycation product which could lead to glomerular injury in type 2 diabetic patients. This study aimed to determine whether there is correlation between glycemic control (HbA1c) and nephropathy diabetic among type 2 diabetic patients in Dr.Moewardi General Hospital Surakarta. Methods: This study is an observational analytic with case control approach. Subjects in this study are type 2 diabetes mellitus patients with nephropathy diabetic and without nephropathy diabetic in Dr. Moewardi General Hospital Surakarta. Data of HbA1c level of subjects in this study were collected from medical records. Sampling was done by purposive sampling with 40 patients as the case and 40 patients as the control. The data were analyzed using chi square test and logistic regression. Result: There is no significant correlation between control glycemic (HbA1c) with nephropathy diabetic with p-value = 0.528 (OR =1.378; CI 95% 0.509-3.727). Multivariate analysis shows that hypertension is the most influenced risk factor (OR = 4.255; CI 95% 1.538-11.437; p = 0.004) followed by duration of diabetes (OR = 3.432; CI 95% 1.254-9.397; p = 0.016, meanwhile dyslipidemia has no significant correlation with nephropathy diabetic (OR = 0.925; CI 95% 0.259-3.303; p = 0.904). Conclution: There is no significant correlation between control glycemic (HbA1c) with nephropathy diabetic in diabetes mellitus type 2 in General Hospital Moewardi Surakarta. Keywords: Glycemic Control (HbA1c), Nephropathy Diabetic, Diabetes Mellitus Type 2
Hubungan antara Kadar Feritin dengan Kreatinin Serum pada Pasien Thalassemia di RSUD Dr. Moewardi Eko Dewi Ratna Utami; Harsono Salimo; Dyah Ratna Budiani
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Patients with thalassemia that underwent routine blood transfusion are developing iron overload. In the state of excess iron, ferritin levels increase. When iron storage capacity has been depleted, free iron will cause tissue damage. One of that damaged organ is kidney. One of parameter used to know the function of kidney is GFR (Glomerular Filtration Rate). A simple way to estimate GFR is serum creatinine. Increased 1-2 mg/dL of creatinine serum showed decrease 50% of GFR. This research was aimed to determine the correlation between ferritin levels and serum creatinine of patients with thalassemia. Methods : A cross-sectional study which the subjects were 30 patients with thalassemia in the pediatric ward RSUD Dr. Moewardi who met the inclusion criteria. Ferritin levels and serum creatinine obtained from medical records or patient report book. Data normality was tested with Shapiro-Wilk normality test. Correlation between ferritin levels and serum creatinine were analyzed with non-parametric correlation test Spearman using Statistical Product and Service Solutions (SPSS) 20.0 for Windows. Results : Ferritin levels ranged from 1004.2 to 9600 ng/mL. Creatinine serum were 0.2 mg/dL; 0.3 mg/dL; 0.4 mg/dL; 0.5 mg/dL with almost equal distribution. Results of the analysis with non-parametric correlation test Spearman obtained R = 0.044 and p = 0.816. Conclusion : There was no correlation between ferritin levels and serum creatinine of patients with thalassemia. Keywords : thalassemia, ferritin, creatinine
Hubungan Andropause dengan Penyakit Jantung Koroner di RSUD Dr. Moewardi Surakarta Hanne Dianta Pramono; Endang Syahrir; Sigit Setyawan
Nexus Kedokteran Klinik Vol 3, No 2 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Andropause is a syndrome of aging that can be interpreted by the cessation of physiological processes in men. It is estimated there are at least 25 million men in America between 40 and 55 years have some degree of andropause. The loss of testosterone can occur in men age 35 years , gradually , with testosterone levels decreased only 1 % to 1.5 % per year. Coronary heart disease is a pathological condition of the coronary arteries ( atherosclerosis ) that causes changes in the structure and function of arteries and decrease blood flow to the heart. Coronary heart disease is a major health problem in developed countries . While the cause of death remains ranked No. 3. Study aimed to analyze the correlation between andropause with coronary heart disease in Dr . Moewardi hospitals Surakarta. Methods : This study was an observational analytic cross sectional approach . Subjects were patients with coronary heart disease and who do not suffer from coronary heart disease who present in Cardiac clinic Dr . Moewardi hospital Surakarta . A total of 104 subjects were selected using purposive sampling method . Data were collected by direct interviews and questionnaires . Data were analyzed by multiple logistic regression analysis and processed with the Statistical Product and Service Solutions ( SPSS ) 16.0 for Windows . Results : Patients with coronary heart disease have a risk of andropause with moderate levels of correlation of 0.32 with the use of contingency correlation test. Conclusions : There is a significant association between andropause with coronary heart disease in elderly men in Surakarta Moewardi Hospital with moderate levels of correlation. Keywords : Andropause , Coronary Heart Disease
Perbedaan Tingkat Kecemasan antara Pasien Diabetes Melitus Tipe 2 Disertai Komplikasi dengan Tanpa Komplikasi di RSUD Dr. Moewardi Nia Anggarani; IGB Indro Nugroho; Sigit Setyawan
Nexus Kedokteran Klinik Vol 3, No 3 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Diabetes mellitus (DM) is referred to as growing epidemic. The prevalence of type 2 diabetes mellitus in Indonesia is 18.6% in urban areas and 9.2% in rural areas. It is estimated that in 2030 the prevalence of DM in Indonesia reached 21.3 million people. Chronic diseases such as diabetes mellitus are associated with the emergence of anxiety disorders. It has been reported that anxiety disorders associated with age, gender, occupation and complications of diabetes mellitus. In addition, an increase in the symptoms of anxiety disorder related to the number and the type of complications suffered by patients with diabetes mellitus. This study aimed to analyze the differences of anxiety level in type 2 diabetes mellitus patients with and without complications in Dr. Moewardi Hospital. Method: 91 type 2 diabetes mellitus patients of Internal Medicine Clinic Dr. Moewardi Hospital participated in a cross-sectional study. 40 patients with complications and 51 patients without complications were recruited with non-probability sampling methods, which was consecutive sampling. Each respondent was given a standard TMAS (Taylor Manifest Anxiety Scale) questionnaire and LMMPI (Lie-scale Minnesota Multiphasic Personality Inventory) questionnaire. The TMAS questionnaire contains 50 questions, which has "yes" or "no" options, and LMMPI questionnaire contains 10 questions, which has "yes" or "no" options. The TMAS questionnaire was employed to estimate the patients symptoms of anxiety. Research data were tested by Chi Square test. Result: The results showed 90% and 70.59% type 2 diabetes mellitus patients with and without complication had anxiety respectively. 8 samples of patients with complications of type 2 diabetes mellitus had severe anxiety, 21 samples had moderate anxiety, and 7 samples had mild anxiety. While in type 2 diabetes mellitus patients without complications, one sample has severe anxiety, 16 samples have moderate anxiety, and 19 samples had mild anxiety. The results of Chi Square test for anxiety in type 2 diabetes mellitus patients showed p < 0.05 (p = 0.024) and for the anxiety level in type 2 diabetes mellitus patients with and without complications showed p < 0.05 (p=0.003). Conclusion: There was difference of anxiety level among type 2 diabetes mellitus patients with and without complications in Dr. Moewardi Hospital. Keywords: type 2 diabetes mellitus with complications, type 2 diabetes mellitus without complications, anxiety level
The Difference of Airway Irritative Effect of Halotane and Isoflurane as Inhalational Anestethic Whendi Setyawan; Marthunus Judin; Bhisma Murti
Nexus Kedokteran Klinik Vol 1, No 2 (2012): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background:Isoflurane and halothane have been used broadly. Airway irritation is one of the side effect from both isoflurane and halothane and have fairly important clinical implication in the provision of both anestethic agent. Methods:The Research is observational analitic research. The population of the research was the patient completed surgery with general anesteshia in IBS(InstalasiBedahSentral) RSUD dr. Moewardi, Surakarta and was transferred to the ward. The data of odynophagia and the incidence of chough were analyzed using Chi Square method. Results:This quote sampling research uses 30 samples divided into two groups, 15 peoples get Isoflurane as their anestethic agent, the other 15 get Halothane. The results of all samples obtained from both groups experienced a sense of hoarseness in the throat. Data incidence of odynophagia obtained that 15 patients of isoflurane experienced odynophagia and 7 patients found in the halothane. Data incidence of chough obtained that 7 patients of isoflurane experienced chough and none of the halothane patient experienced chough. Analitical result on the incidence of odynophagia obtained that patients given isoflurane are at risk for odynophagia 35.13 times greater than halothane, and the increased risk was statistically significant (OR: 35.13, 95% CI 1.78 to 693.30, p = 0.002) and the results cough incidence analysis, found patients given isoflurane are at risk for experiencing cough 27.35 times greater than halothane, and the increased risk was statistically significant (OR: 27.35, 95% CI 1:36 to 539.7, p = 0.004). Conclusions:The conclusions of this study isisoflurane has the effect of irritating the respiratory tract is greater than halothane as inhaled anesthetic. Isoflurane itself can still be used in elective surgery such as halothane when accompanied by adequate premedication Keywords:Isoflurane-Halothane-Iritation-Airway.

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