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<![CDATA[The Impact and Mitigation of Forest Fire for Biodiversity in Indonesia ]]>
<![CDATA[Ardhana, I Putu Gede]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[The purpose of this study was to assess and mitigate the impact of wildfires for biodiversity in Indonesia. Firstly researcher presented information about destruction of forests that spread throughout Indonesia. Forest degradation is caused by failure of government policies in addressing the implementation of concession to investors who were rife on 1967 and concerned this thing, the deforestation system of TPI changed into TPTI, HTI, Joint enterprise, HGU and APL which were caused to decline forest cover. Secondly researcher presented information about forest fires that trigger by the destruction of forests due to deforestation and forest degradation in some areas of concessions and other areas. The collected data has been indicated that forest fires have occurred since 1960 until 2015. These conditions clearly destroy the habitat of flora and fauna that exist in each forest ecosystems. The mitigation that needs to be done is for government to carry out rehabilitation, reforestation, restoration of forest lands where had been burned, so that biodiversity can be recovered, and conservation of germ plasma to be need in each forest ecosystem. The method used in this research was descriptive method by reviewing of regulations and legislation and approach to literature. The study was later described, narrated and in the interpretation and arranged in the form of papers. From these results it can be concluded that the fires is the classic phenomenon that occurs repeatedly and extends preceded by the destruction of forests due to wide spread deforestation and forest degradation in Indonesia.Keywords: biodiversity; degradation and forest fires; impact; mitigation]]>
<![CDATA[Prospect of Bioremediation Using Synthetic Biology Approach in Indonesia ]]>
<![CDATA[Kemal, Rahmat Azhari]]>;
<![CDATA[Novianti, Annisa]]>;
<![CDATA[Rini, Ika A.]]>;
<![CDATA[Fatmawati, Ruli]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[Cellular systems can be engineered by synthetic biology approach to make a controllable bioremediation system. Several teams competing in the International Genetically Engineered Machine (iGEM) competition have utilized the potency of synthetic biology for bioremediation. This review highlighted several ideas. One of them is the designing a whole-cell biocatalyst that can degrade PET component in plastic waste. Rice blast (Magnaporthe grisea) produces cutinase, thus its gene encoding cutinase can be used as substitute in the system. Regulation of the application is also discussed. It is hoped that research and implementation of bioremediation using synthetic biology in Indonesia can be developed.Keywords: Biodiversity; bioremediation; iGEM; Indonesia; synthetic biology]]>
<![CDATA[Virtual Screening of Natural Compounds for HIV 1 Reverse Transcriptase Inhibitor as Potential Drugâs Candidate ]]>
<![CDATA[Fadilah, Rizka Elan]]>;
<![CDATA[Fauzi, Ahmad]]>;
<![CDATA[Widiansyah, Arindra Trisna]]>;
<![CDATA[Wijayanti, Erna]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[AIDS is one of mayor health problem in the world, commonly caused by Human Immunodeficiancy virus 1 (HIV-1). Reverse transcriptase is the target of the most widely used treatments for AIDS. One of the problem from treatments is drug resistant. This research aim to discover a new potential drugâs candidate from natural compound to inhibit activity of HIV 1 Reverse Transcriptase. Top ten compounds from Specs Natural Products database as the result of virtual screening by MTIOpenScreen are docked and analyzed using Pyrx 0.8 software. Based on analysis and visualization of 2D and 3D sructure using LigPlus and PyMol softwares, known that ZINC57657 (-8 Kcal/mol)and common drug against HIV 1 Reverse Transcriptase, Lamivudine (-5,6 Kcal/mol) equally capable to bind in several amino acids (Thr 131 and Gln 23) located in the active site of HIV 1 Reverse Transcriptase.Keywords: Drugâs candidate; HIV 1 reverse transcriptase; natural compounds; virtual screening]]>
<![CDATA[6-Gingerol from Zingiberaceae as a Result of Reverse Docking for Prostateâs Cancer Potential Drug Candidate ]]>
<![CDATA[Setyanto, Haqqi Anajili]]>;
<![CDATA[Widiansyah, Arindra Trisna]]>;
<![CDATA[Mustofa, Zainul]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[Prostate cancer is a cancer that attacks the prostate gland causing the death rate which is high enough. One of the causes of prostate cancer is the androgen receptor (AR) in the gland cells that initiates the formation of excess cell proliferation, thus causing prostate cancer. AR inhibitor that is known is antiandrogen (biculatamide and enzalutamide). This study aimed to test the 6-gingerol compound of ginger as an AR inhibitor drug candidate for prostate cancer using silico methode. The 3D structure of the 6-gingerol compound was taken from PubChem, the prediction of targeted protein used SwissTargetPrediction and Pharmapper, analysis and docking 6-gingerol and antiandrogens with AR using Pyrx software, visualization compounds and protein interactions using PyMOLsoftware. Visualization results shows that the interaction of 6-gingerol, biculatamide, and enzalutamide with AR have the same site. This proves that the 6-gingerol is potential as anAR inhibitor candidate.Keywords: 6-gingerol; prostateâs cancer; reverse docking]]>
<![CDATA[Growth of generative explants of Moringa oleifera on different culture conditions ]]>
<![CDATA[Muslihatin, Wirdhatul]]>;
<![CDATA[Rizkia, Hanum Laila]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[In vitro culture is more effective propagation technique because the propagation time is faster than conventional propagation  so the achievement of the results is  in favor of the improvement program and faster  spread of Moringa oleifera. The objectives of this study were to determine the effect of carbon source and photoperiod on the growth of generative explants of M. oleifera in vitro. The method performed were inoculation of generative explans on MS Medium, observation growth of callus, and measurement of fresht weigth of callus. The generative explants used were M. oleifera seeds grown on MS medium with 3%, 5%, 7% and 9% sucrose and then they were cultured with photoperiod of 12/12, 14/10, and 16/8 hours (light/dark). The results showed that the best response of growth callus was indicated by the explants cultured on 3% sucrose medium in the photoperiod of 12/12.Keywords: Moringa oleifera; nodule; photoperiod; sucrose ]]>
<![CDATA[Ethnobotany Study of Kelakai (Stenochlaena palustris Bedd) as an Endemic Fern at Central of Kalimantan ]]>
<![CDATA[Zannah, Fathul]]>;
<![CDATA[Amin, Mohamad]]>;
<![CDATA[Suwono, Hadi]]>;
<![CDATA[Lukiati, Betty]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[This ethnobotany study of Kelakai (Stenochlaena palustris) analyzes the aspect of the relationship between plant and people, especially about the indigenous knowledge such as the benefit and how the use of this endemic fern. Methods included participant observation and semi structured interviews with a total of one hundred and ten participants were conducted in Palangkaraya, at Central of Kalimantan. The result shows that the Dayak ethnic society in Palangkaraya believe that Kelakai (Stenochlaena palustris) useful to increase milk production, increase hemoglobin, and as anti aging. Consequently, identifying this endemic fernâs benefit can help to preserve the local wisdom of Dayak ethnic group and natural plant conservation. Keywords: Central of Kalimantan; endemic fern; ethnobotany; Stenochlaena palustris]]>
<![CDATA[Distribution of Diurnal Bird in Pine Forests and Citrus Orchard in Bedengan, Selorejo Village, Malang ]]>
<![CDATA[Polii, Oky A.I.]]>;
<![CDATA[Yanuwiadi, Bagyo]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[Selorejo village located in the district of Dau, Malang regency, is a village that has a lot of potential for nature tourism. Selorejo village in the region of Malang the north, to the village of Ivory Kulon as boundary north, Tegalweru village as the East boundary, and the boundary south is the Petung Sewu village. One potential place for tourism is Bedengan. A location which has a camping ground yet around the site are some kind variety of vegetation types like pine forests and citrus groves dominated by local residents.. The purpose of this research is to determine distribution spatial and temporal diurnal birds in Bedengan and to found bird in citrus orchards and pine forests. This research was conducted in May-October 2015. The Methods is the point count method that have been modified, the method of observation the birds. and data analysis include F (frequency), K (Density), FR (Relative Frequencies), KR (Relative Density), Important Value Index (IVI), temporal using Microsoft Office Excel 2007 software and Spatial design of birds using Photoshop. From the results obtained, At pine forest land is dominated by Glossy swiftlet (Collocalia esculenta). On citrus orchard land dominated by Sooty-headed bulbul (Pycnonotus aurigaster). some birds in pine forests often conducting activities in the air like a Glossy swiftlet (Collocalia esculenta). Heading like Spotted dove (Streptopelia chinensis), sooty-headed bulbul (Pycnonotus aurigaster), Rusty-breasted cuckoo (Cacomantis sepulcralis). At branching like Olive-backed tailorbird (Orthotomus sepium). Javan kingfisher (Halcyon cyanoventris), Eurasian tree sparrow (Passer montanus). Whereas birds in the orange orchard did activity in the Air like Glossy swiftlet (Collocalia esculenta). On Heading like sooty-headed bulbul (Pycnonotus aurigaster) and Eurasian tree sparrow (Passer montanus). The results showed that on the morning the dominate in citrus orchard is Glossy swiftlet followed by the Sooty-headed bulbul and Javan kingfisher while the pine forest is Sooty-headed bulbul followed by Glossy swiftlet and the Eurasian tree sparrow. At noon that dominate in orange orchard is Glossy swiftlet followed by the Sooty-headed bulbul and Spotted dove while the pine forests dominates by the Sooty-headed bulbul followed by Glossy swiftlet and Olive-backed tailorbird. In the afternoon which dominates the citrus orchard is Glossy swiftlet while the dominate in pine forest is Glossy swiftlet followed by Javan kingfisher and Sooty-headed bulbul.Keywords: Distribution; diurnal bird; Bedengan]]>
<![CDATA[Sustainability of Organic Farming System of Lowland Paddy in Deli Serdang Regency, North Sumatra Province ]]>
<![CDATA[Panjaitan, Ernitha]]>;
<![CDATA[Indradewa, Didik]]>;
<![CDATA[Martono, Edhi]]>;
<![CDATA[Sartohadi, Junun]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[The objectives of this study was to assess the farming system of organic lowland paddy to soil pollution compared with conventional farming system in Deli Serdang Regency. An environmental assesment in this research as limited to the soil pollution caused by pesticides and chemical fertilizers. Soil samples were grouped into low and upper layers. Each soil composites was collected from ten sampling points. Which each consist of 5 sampling points of organic paddy farming system and 5 sampling points of conventional paddy farming  system. The results showed that the levels of pesticides and nitrate in paddy soil was influenced by soil layers, meanwhile although was not statistically significant, the levels of pesticides and nitrate increased due to the way of cultivation.The results indicated that in general the soil pollution on organic paddy farming system was lower than conventional farming. Levels of pesticides and nitrate in the soil layer 20-40 cm was higher than levels of pesticides in the 0-20 cm. Pesticides and nitrate leached by water gets into the deeper layers of soil. The increased level of pesticides in soil of conventional farming was higher 0.96 ppm during the dry season and lowest 0.38 ppm in the rainy season compared with organic farming. The increased level of nitrate in soil of conventional farming was higher 0.45 ppm during the rainy season compared with organic farming, however in the dry season, the level of nitrate in conventional farming was lowest 2.32 ppm compared with organic farming.Keywords: conventional farming; organic farming; paddy; sustainability]]>
<![CDATA[Antidiabetic and Antidiarrheal Activity from Extract of Namnam (Cynometra Cauliflora) Leaf ]]>
<![CDATA[Sumarlin, La Ode]]>;
<![CDATA[Suprayogi, Agik]]>;
<![CDATA[Rahminiwati, Min]]>;
<![CDATA[Satyaningtijas, Aryani]]>;
<![CDATA[Sukandar, Dede]]>;
<![CDATA[Nugraha, Ahmad Tjahja]]>;
<![CDATA[Amalia, Ika]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[In addition to decorate the yard, plant namnam (Cynometra cauliflora) turns out to have merit as an herbal remedy because it has biological activities such as antimicrobial, antioxidant, cytotoxic, antiviral, anti-inflammatory, antitumor and antidiabetic. It is study will add to scientific information about plants Namnam the potential to be developed as a functional food and natural herbal remedies in particular as antidiabetic agents and antidiarrheal. Ability as an antidiabetic agent tested by the ability of plants Namnam inhibit α-amylase. Meanwhile, antidiarrheal activity will be tested against the isolated rabbit intestine recorded on kymograph. The analysis showed that the leaf extract of plant Namnam (C. cauliflora) at a concentration of 100 mg/mL, 250 mg/mL and 300 mg/mL each is able to inhibit α-amylase activity by 20.68%; 70.24% and 72.59% and IC50 of 200.67 ± 0.53 mg/mL. The study also showed that the sample tested has the ability to decrease the activity of isolated rabbit intestine in the pattern described in kymograph. Thus the plant leaves Namnam (C. cauliflora) potential to be developed as antidibetes agent and antidiarrheal. This may partially explain the use in traditional medicine for the treatment of diarrhea. These results support their use in folk medicine.Keywords: Antidiabetic, antidiarrheal,  Cynometra cauliflora, Namnam]]>
<![CDATA[Bioinformatic Analysis of Drug Candidate Compounds for Acquired Immunodeficiency Syndrome ]]>
<![CDATA[Sukoco, Restu Megadiana]]>;
<![CDATA[Fauzi, Ahmad]]>;
<![CDATA[Nuha, Ulin]]>
<![CDATA[ Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015 ]]>
Publisher : <![CDATA[Proceeding International Conference on Global Resource Conservation ]]>
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<![CDATA[AIDS is a syndrome caused by HIV. The immune system of AIDS patient was too weak to fight off many infections. Many drugs developed to overcome these deadly disease. In this study, bioinformatic analysis performed on some drug candidate compounds that under development of FDA for AIDSâ patient. The drug candidate compounds are Amdoxovir, Alovudine, Elvucitabine, Dexelvucitabine, Capravirine, Darunavie, Calanolide-A, Tipranavir and Enfuvirtide. Molinspiration and preADMET web server has been used as tool for analyzing that drugs. As a results, our study revealed that not all of these drug candidate compounds fulfilled the Lipinskiâs rule of five and toxicity test standart in silico.Keywords:Bioinformatic analysis; AIDSâ drug; Lipinskiâs rule; toxicity test]]>
