Article Per Year (5 Year)
p-Index From 2021 - 2026
2.59
P-Index
This Author published in this journals
All Journal International Journal of Evaluation and Research in Education (IJERE) Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Biogenesis: Jurnal Ilmiah Biologi Biotropika Proceeding International Conference on Global Resource Conservation Jurnal Pendidikan Biologi Indonesia Biology, Medicine, & Natural Product Chemistry Mutiara Medika: Jurnal Kedokteran dan Kesehatan Bioeksperimen: Jurnal Penelitian Biologi Journal of Tropical Biodiversity and Biotechnology Jurnal Pendidikan Biologi BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) Jurnal Penelitian Pendidikan IPA (JPPIPA) BIOEDUKASI Biosfer: Jurnal Pendidikan Biologi Saintifik : Jurnal Matematika, Sains, dan Pembelajarannya Jurnal Jamu Indonesia Bio-Inoved : Jurnal Biologi-Inovasi Pendidikan JPPIPA (Jurnal Penelitian Pendidikan IPA) Prosiding Seminar Nasional Biologi, Teknologi dan Kependidikan (Biotik) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal PRIMED:Primary Education Journal atau Jurnal Ke-SD An Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) Jurnal Kedokteran Hewan Jurnal Ilmu Hayat Indonesian Journal of Jamu JPP (Jurnal Pendidikan dan Pembelajaran)
Betty Lukiati
Universitas Negeri Malang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 42 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 42 Documents
Search

 1   2   3   4   5 
REVIEW: PENYEBAB GANGGUAN AUTIS MELALUI JALUR NEUROINFLAMASI Putri Purnama Sari, Alvina; Amin, Mohamad; Lukiati, Betty
Bioeksperimen: Jurnal Penelitian Biologi Vol 3, No 2: September 2017
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v3i2.5177

Abstract

Autis merupakan gangguan perkembangan yang kompleks pada anak yang dipengaruhi oleh banyak faktor. Faktor penyebab autis diantaranya genetik, lingkungan, gangguan sistem imun, dan inflamasi. Inflamasi terjadi karena adanya mediator yang mengganggu kerja suatu jaringan sehingga menimbulkan respon terhadap mediator tersebut. Salah satu mediator inflamasi adalah sitokin (IL-6 dan TNF-α).  IL-6 dan TNF-α dengan jumlah tinggi dalam otak mengakibatkan gangguan atau penurunan  adhesi dan migrasi sel saraf yang mengakibatkan terganggunya kerja dari Blood Brain Barrier (BBB) atau sawar darah otak yang berfungsi menjaga normalitas homeostasis sistem saraf pusat.  Inflamasi yang terjadi pada sel otak atau neuroinflamasi yang sudah  kronis menjadi salah satu penyebab terjadinya gangguan autis pada anak.
Ethnobotany Study of Kelakai (Stenochlaena palustris Bedd) as an Endemic Fern at Central of Kalimantan Zannah, Fathul; Amin, Mohamad; Suwono, Hadi; Lukiati, Betty
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

Abstract

This ethnobotany study of Kelakai (Stenochlaena palustris) analyzes the aspect of the relationship between plant and people, especially about the indigenous knowledge such as the benefit and how the use of this endemic fern. Methods included participant observation and semi structured interviews with a total of one hundred and ten participants were conducted in Palangkaraya, at Central of Kalimantan. The result shows that the Dayak ethnic society in Palangkaraya believe that Kelakai (Stenochlaena palustris) useful to increase milk production, increase hemoglobin, and as anti aging. Consequently, identifying this endemic fern’s benefit can help to preserve the local wisdom of Dayak ethnic group and natural plant conservation. Keywords: Central of Kalimantan; endemic fern; ethnobotany; Stenochlaena palustris
Bioinformatics approach based research of profile protein carbonic anhydrase II analysis as a potential candidate cause autism for the variation of learning subjects biotechnology Ningrum, Dian Eka A. F.; Amin, Mohamad; Lukiati, Betty
Jurnal Pendidikan Biologi Indonesia Vol 3, No 1 (2017): MARCH
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (515.262 KB) | DOI: 10.22219/jpbi.v3i1.3799

Abstract

This study aims to determine the needs of learning variations on Biotechnology courses using bioinformatics approaches. One example of applied use of bioinformatics in biotechnology course is the analysis of protein profiles carbonic anhydrase II as a potential cause of autism candidate. This research is a qualitative descriptive study consisted of two phases. The first phase of the data obtained from observations of learning, student questionnaires, and questionnaires lecturer. Results from the first phase, namely the need for variations learning in Biotechnology course using bioinformatics. Collecting data on the second stage uses three webserver to predict the target protein and scientific articles. Visualization of proteins using PyMOL software. 3 based webserver which is used, the candidate of target proteins associated with autism is carbonic anhydrase II. The survey results revealed that the protein carbonic anhydrase II as a potential candidate for the cause of autism classified metaloenzim are able to bind with heavy metals. The content of heavy metals in autistic patients high that affect metabolism. This prediction of protein candidate cause autism is applied use to solve the problem in society, so that can achieve the learning outcome in biotechnology course.
Keterampilan Berpikir Kritis Mahasiswa STKIP Yapim Maros Pada Mata Kuliah Evolusi Jirana, Jirana; Amin, Mohammad; Suarsini, Endang; Lukiati, Betty
Jurnal Saintifik Vol 5, No 1 (2019): Volume 5 Nomor 1
Publisher : Fakultas MIPA UNSULBAR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31605/saintifik.v5i1.192

Abstract

Mata kuliah evolusi merupakan salah satu mata kuliah yang dianggap sulit oleh mahasiswa, sulitnya pemahaman mahasiswa terhadap konsep evolusi disebabkan oleh beberapa masalah sehingga perlu dilakukan beberapa observasi terhadap komponen-komponen dalam proses pembelajaran Evolusi. Penelitian ini bertujuan untuk menganalisis Keterampilan Berpikir mahasiswa terhadap Mata Kuliah Evolusi di Universitas Sulawesi Barat Penelitian ini menggunakan metode survey dengan cara penyebaran angket dan pemberian tes untuk mengetahui pengetahuan mahasiswa tentang konsep evolusi. Berdasarkan survey yang dilakukan terhadap mahasiswa STKIP Yapim Maros Program Pendidikan Biologi dengan 36 orang responden menunjukkan bahwa Keterampilan Berpikir Kritis Mahasiswa STKIP Yapim Maros. Berdasarkan hasil analisis yang didapatkan, maka dapat disimpulkan bahwa keterampilan berpikir mahasiswa biologi STKIP Yapim Maros terhadap mata kuliah Evolusi masih rendah. Oleh karena itu perlu dilakukanpembenahan dalam penelitian lanjutan.Kata kunci: Berpikir Kritis, Evolusi, Pembelajaran
PROFIL KETERAMPILAN BERPIKIR ANALITIS MAHASISWA CALON GURU IPA DALAM PERKULIAHAN BIOLOGI UMUM Astriani, Dyah; Susilo, Herawati; Suwono, Hadi; Lukiati, Betty
Jurnal Penelitian Pendidikan IPA Vol 2, No 2 (2017): Desember 2017
Publisher : Perkumpulan Pendidik IPA Indonesia (PPII)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jppipa.v2n2.p66-70

Abstract

Keterampilan berpikir analitis merupakan kemampuan yang harus dikuasai mahasiswa untuk menyelesaikan masalah dalam biologi. Penelitian ini merupakan penelitian deskriptif yang bertujuan untuk mendeskripsikan kemampuan berpikir analitis mahasiswa. Sejumlah 38 mahasiswa yang telah menempuh mata kuliah biologi umum menjadi subyek penelitian. Instrumen yang digunakan pada penelitian ini berupa tes tipe uraian yang mengacu pada keterampilan berpikir analisis yang terdiri dari membedakan (differentiating), mengorganisasi (organizing), dan menghubungkan (attributing) masing-masing indikator 3 soal. Berdasarkan analisis data dideskripsikan kemampuan analisis mahasiswa pada t indikator membedakan 3,01 (baik), mengorganisasikan 2,93 (baik), dan menghubungkan 2,47 (kurang baik). Indikator menghubungkan perlu mendapatkan perhatian lebih.Kata Kunci: keterampilan berpikir analitis, profil, dan biologi umum.
Senyawa Alami Bawang Putih Tunggal sebagai Inhibitor LpxC Bakteri Pseudomonas aeruginosa melalui Virtual Screening Fitriana, Nur; Lestari, Sri Rahayu; Lukiati, Betty
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 18, No 1: January 2018
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.180111

Abstract

Pseudomonas aeruginosa merupakan salah satu bakteri Gram negatif penyebab infeksi nosokomial yang memiliki resistensi tinggi terhadap berbagai antibiotik karena adanya lipid A, komponen LPS bersifat toksik pada inang. Sintesis lipid A dimulai dari Kdo2 -lipid A, difasilitasi oleh enzim LpxC. Enzim LpxC merupakan target pengembangan antibiotik karena adanya kofaktor Zn2+. Bawang putih tunggal merupakan herbal potensial pengganti antibiotik sintetis. Alliin, Allicin dan Ajoene yang terkandung dalam bawang putih tunggal memiliki aktivitas antibakteri. Penelitian ini bertujuan memprediksi potensi senyawa organosulfur bawang putih tunggal sebagai agen antibakteri melalui virtual screening menggunakan metode molecular docking. Metode yang dilakukan adalah memprediksi potensi senyawa organosulfur menggunakan web server PASS dan melakukan docking untuk mengetahui interaksi ligan-protein target. Hasil penelitian menunjukkan, senyawa organosulfur berpotensi sebagai antibakteri, antibiotik, dan immunomodulator. Aktivitas antibakteri terbaik ditunjukkan oleh senyawa Alliin dengan nilai afinitas pengikatan -5,2 kkal/mol. Semua senyawa organosulfur memiliki sisi aktif yang sama dengan kontrol (Ciprofloxacin dan Imipenem) pada enzim LpxC. Sisi aktif ditunjukkan dengan adanya residu asam amino (Ser295, Val182, dan Tyr 296) yang berikatan dengan ikatan hidrogen dan interaksi hidrofobik (Phe152, Phe181, Gly85, Phe176, Ala84, Val182, Ser180, Ile241, Leu86, Tyr296, Ser295 dan Met297) antara ligan-protein target.
PROFIL KETERAMPILAN BERPIKIR ANALITIS MAHASISWA CALON GURU IPA DALAM PERKULIAHAN BIOLOGI UMUM Astriani, Dyah; Susilo, Herawati; Suwono, Hadi; Lukiati, Betty
Jurnal Penelitian Pendidikan IPA Vol 2, No 2 (2017): Desember 2017
Publisher : Perkumpulan Pendidik IPA Indonesia (PPII)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jppipa.v2n2.p66-70

Abstract

Keterampilan berpikir analitis merupakan kemampuan yang harus dikuasai mahasiswa untuk menyelesaikan masalah dalam biologi. Penelitian ini merupakan penelitian deskriptif yang bertujuan untuk mendeskripsikan kemampuan berpikir analitis mahasiswa. Sejumlah 38 mahasiswa yang telah menempuh mata kuliah biologi umum menjadi subyek penelitian. Instrumen yang digunakan pada penelitian ini berupa tes tipe uraian yang mengacu pada keterampilan berpikir analisis yang terdiri dari membedakan (differentiating), mengorganisasi (organizing), dan menghubungkan (attributing) masing-masing indikator 3 soal. Berdasarkan analisis data dideskripsikan kemampuan analisis mahasiswa pada t indikator membedakan 3,01 (baik), mengorganisasikan 2,93 (baik), dan menghubungkan 2,47 (kurang baik). Indikator menghubungkan perlu mendapatkan perhatian lebih.Kata Kunci: keterampilan berpikir analitis, profil, dan biologi umum.
Pengujian Potensi Jus Tomat (Lycopersicum esculentum) Sebagai Terapi Herbal Pada Tikus Rattus norvegicus Hiperkolesterolemik Dina Aribah; Alif Rofiqotun Nurul Alimah; Anindya Nirmala Permata; Betty Lukiati
Biogenesis: Jurnal Ilmiah Biologi Vol 4 No 2 (2016)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v4i2.2512

Abstract

Hypercholesterolemia defines as the increasing of cholesterol serum that more than the normal limit. WHO (2011) on 2008 at Indonesian said that hypercholesterolemia prevalence of woman approach about 37,2% and for man about 32,8%. Tomato contain lycopene is one powerful antioxidant and can manage cholesterol metabolism with blocked the HMG-KoA enzyme reductase (enzyme for cholesterol synthesis in hepar). This study aims to determine the effect of tomato juice on the cholesterol levels in the blood of hypercholesterolemic rats and to find the effective dosis of tomato juice to decrease the cholesterol of hypercholesterolemic rats. The object of research covering 20 wistar rats (Rattus norvegicus) male 2-3 months old with 50-150g weight. The rats were divided into five groups and four replications: normal (K-), high-fat diet (K+), high-fat diet+tomato juice 200mg/100gBB (P1), high-fat diet+tomato juice 400mg/100gBB (P2), high-fat diet+tomato juice 800mg/100gBB (P3). Tomato juice was given orally for one month every day. At the end of the treatment of rats was dissected to take blood from the heart. Data were analyzed statistically with one-way ANAVA with α=0,05. The results showed that the tomato juice affects on the cholesterol levels of blood serum of hypercholesterolemic rats and the effective dose of tomato juice used in this study was 800mg/100gBB.
Bioinformatics approach based research of profile protein carbonic anhydrase II analysis as a potential candidate cause autism for the variation of learning subjects biotechnology Dian Eka A. F. Ningrum; Mohamad Amin; Betty Lukiati
JPBI (Jurnal Pendidikan Biologi Indonesia) Vol. 3 No. 1 (2017): MARCH
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/jpbi.v3i1.3799

Abstract

This study aims to determine the needs of learning variations on Biotechnology courses using bioinformatics approaches. One example of applied use of bioinformatics in biotechnology course is the analysis of protein profiles carbonic anhydrase II as a potential cause of autism candidate. This research is a qualitative descriptive study consisted of two phases. The first phase of the data obtained from observations of learning, student questionnaires, and questionnaires lecturer. Results from the first phase, namely the need for variations learning in Biotechnology course using bioinformatics. Collecting data on the second stage uses three webserver to predict the target protein and scientific articles. Visualization of proteins using PyMOL software. 3 based webserver which is used, the candidate of target proteins associated with autism is carbonic anhydrase II. The survey results revealed that the protein carbonic anhydrase II as a potential candidate for the cause of autism classified metaloenzim are able to bind with heavy metals. The content of heavy metals in autistic patients high that affect metabolism. This prediction of protein candidate cause autism is applied use to solve the problem in society, so that can achieve the learning outcome in biotechnology course.
Quercetin: the bioactive compound from Allium cepa L. as anti-inflammation based on in silico screening Mohamad Amin; Kurniawan Setia Putra; Ihya Fakhrurizal Amin; Nanda Earlia; Dina Maulina; Betty Lukiati; Umie Lestari
Biology, Medicine, & Natural Product Chemistry Vol 7, No 1 (2018)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (476.812 KB) | DOI: 10.14421/biomedich.2018.71.27-31

Abstract

Inflammation is a tissue injury that occurs due to physical trauma or microbiological substances that involve the activities of many cell types. Inflammation can be prevented using the natural medicines from Allium cepa L. Quercetin is one of the bioactive compounds found in Allium cepa L and has been reported to have anti-inflammatory activity. The natural medicines have been used to minimize non-steroidal anti-inflammatory drugs. This study aims to investigated the modeling structures and the protein receptor from quecertin in inflammation mechanism and their optimization of the effectiveness in the human body. The bioinformatics tools used in this study are the database of quercetin compounds, Pubchem and Swis Target Prediction protein prediction databases, PyRx 0.8 molecular docking software, ligand docking, and binding site analysis with PyMOL and LigPlus software. The results from in silico show that quercetin compounds can interact with Muscleblind-like protein 1 target protein with a Binding Affinity minus value which is not much different from the dexamethasone compound. Dexamethason is a standart because it is a corticosteroid drug that can be used as an anti-inflammatory to reduce inflammation, allergic reactions, arthritis and other inflammatory diseases.
Co-Authors Abda Abda Abdul Fattah Noor Abdul Gofur Abdul Gofur AD. Corebima Agus Muji Santoso Alif Rofiqotun Nurul Alimah Alvina Putri Purnama Sari Alvina Putri Purnama Sari Anindya Nirmala Permata Anindya Nirmala Permata Arwinda Probowati Atik Kurniawati Balqis balqis Bayu Guruh Binangkit Dian Eka A. F. Ningrum Dianing Eka Pupitasari Dina Aribah Dina Maulina DYAH ASTRIANI Eko Sri Sulasmi Endang Suarsini Fatchur Rohman Fathul Zannah Fitriani, Rita Frida Kunti Setiowati Hadi Suwono Hanzen, W.F Edi Hendra Susanto Hera Adiwijaya Herawati Susilo Ibrohim Ida Rahmawati Ihya Fakhrurizal Amin Jeni Jeni Jeni Jirana, Jirana Khaq, Rizki Amalia Nurul Kurniawan Setia Putra Liah Badriah M. Amien Rais M. Saiful Fahmi M. Saiful Fahmi, M. Saiful Fahmi Mariana Ade Cahaya Miftahul Mufinadiroh Mimien Henie Irawati Mohamad Amin Mohamad Amin Mohamad Amin Mohamad Amin Mohamad Amin Mohamad Amin Mohamad Amin Mohamad Amin Mohamad Amin Mohamad Amin Mohammad Amin Mohammad Amin Mohammad Amin Mohammad Amin Muhamad Khoirul Anwar, Muhamad Khoirul Muhammad Khalil Muhammad Saefi Muhammad Shobirin Mumun Nurmilawati Murni Sapta Sari Muslihasari, Adzimatnur Nanda Earlia Nazilatul Khoiroh Nelda Anasthasia Serena Ningrum, Dian Eka A. F. Novia Sigma Amalina Nugrahaningsih N, Nugrahaningsih Nugrahaningsih Nugrahaningsih Nur Fitriana Nur Fitriana Nursyahbani Saraha Poppy Rahmatika Primandiri Puspitasari, Dianing Eka Putri Diyah Anggraini Putri Purnama Sari, Alvina Putri Purnama Sari, Alvina Risanti Dhaniaputri Siti Aisyah Firdani Siti Imroatul Maslikah Siti Nur Arifah Sitoresmi Parabaningtyas Sitoresmi Prabaningtyas Sitorus, Mido Ester Solly Aryza Sri Rahayu Lestari Sulistiono Sulistyo Dwi Kartining Putro Sulistyo Dwi Kartining Putro, Sulistyo Dwi Kartining Susriyati Mahanal Sutiman Bambang Sumitro Tahir, Jirana Triastono Imam Prasetyo Umi Hasanah, Umi Umie Lestari Utami Sri Hastuti W. F. Edi Hanzen W.F Edi Hanzen Widodo Widodo Yayoi Kodama Yessi Hermawati Zauhara Faiqohtun Wuriana