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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan ACTA VETERINARIA INDONESIANA Jurnal Primatologi Indonesia Jurnal Sain Veteriner VALENSI Jurnal Veteriner Majalah Kedokteran Bandung Proceeding International Conference on Global Resource Conservation Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat BERITA BIOLOGI Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) ARSHI Veterinary Letters JITPI : Jurnal Ilmu Dan Teknologi Peternakan Indonesia (Indonesian Journal of Animal Science and Technology) JURNAL KAJIAN VETERINER Narra J Jurnal Pusat Inovasi Masyarakat Jurnal Kedokteran Hewan Borneo Journal of Pharmacy al Kimiya : Jurnal Ilmu Kimia dan Terapan

Agik Suprayogi

Departemen Anatomi, Fisiologi, Dan Farmakologi, Sekolah Kedokteran Hewan Dan Biomedis, Institut Pertanian Bogor, Kampus IPB Darmaga, Bogor 16680

Author-ID : 221077

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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Antidiabetic and Antidiarrheal Activity from Extract of Namnam (Cynometra Cauliflora) Leaf Sumarlin, La Ode; Suprayogi, Agik; Rahminiwati, Min; Satyaningtijas, Aryani; Sukandar, Dede; Nugraha, Ahmad Tjahja; Amalia, Ika
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

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In addition to decorate the yard, plant namnam (Cynometra cauliflora) turns out to have merit as an herbal remedy because it has biological activities such as antimicrobial, antioxidant, cytotoxic, antiviral, anti-inflammatory, antitumor and antidiabetic. It is study will add to scientific information about plants Namnam the potential to be developed as a functional food and natural herbal remedies in particular as antidiabetic agents and antidiarrheal. Ability as an antidiabetic agent tested by the ability of plants Namnam inhibit Î±-amylase. Meanwhile, antidiarrheal activity will be tested against the isolated rabbit intestine recorded on kymograph. The analysis showed that the leaf extract of plant Namnam (C. cauliflora) at a concentration of 100 mg/mL, 250 mg/mL and 300 mg/mL each is able to inhibit Î±-amylase activity by 20.68%; 70.24% and 72.59% and IC50 of 200.67 Â± 0.53 mg/mL. The study also showed that the sample tested has the ability to decrease the activity of isolated rabbit intestine in the pattern described in kymograph. Thus the plant leaves Namnam (C. cauliflora) potential to be developed as antidibetes agent and antidiarrheal.Â This may partially explain the use in traditional medicine for the treatment of diarrhea. These results support their use in folk medicine.Keywords: Antidiabetic, antidiarrheal, Â Cynometra cauliflora, Namnam

POTENSI EKSTRAK PEGAGAN (Centella Asiatica) DAN KUNYIT (Curcuma longa) UNTUK MENINGKATKAN AKTIVITAS ENZIM GLUTATION PEROKSIDASE (GSH Px) PADA JARINGAN HATI TIKUS [Potency of Centella asiatica and Curcuma longa Extracts in Increasing Glutathione Peroxidase (GSH-Px) Enzyme Activities in The Liver Tissue of Rats] Aswani, Tuti; Manalu, Wasmen; Suprayogi, Agik; Rahminiwati, Min
BERITA BIOLOGI Vol 14, No 3 (2015)
Publisher : Research Center for Biology-Indonesian Institute of Sciences

Â This experiment was designed to study the effect of pegagan (Centella asiatica) and turmeric (Curcuma longa) extracts on the activities of glutathione peroxidase (GSH- Px) in liver of white Spraque Dawley rat aged 2 months old with average weight of 200 grams. Pegagan was extracted using infuse method, and turmeric was extracted using dekokta method. The activity of GSH-Px was measured using Flohe and Gunzlerâs methods. Extract pegagan and turmeric were assumed to have both preventive and curative treatments. For the preventive treat- ment, extract pegagan and turmeric at concentrations of 22.05 mg/ml : 184.1 mg/ml could increased the activity of GSH-PX enzyme, i.e. 232.60 Â± 21.40 mU / mgprotein. This was approximately 79% than the levels of GSH- Px enzyme in normal liver without paracetamol which was 190.78 Â± 9.28 mU/mgprotein. For the curative treatment, extract pegagan and tumeric at concentration of 22.05 mg/ml : 184.1 mg/ml could improved GSH- Px enzyme activity (i.e. 239.01 Â± 47.40 mU/ mgprotein). This figure was about 92% higher than the levels of GSH-Px enzyme in the liver normal without paracetamol which was 190.78 Â± 9.28 mU/mg protein. Pegagan and turmeric extracts with a high concentration could increased the activity of GSH-Px enzyme, thus potential as curative treatment.

PERBAIKAN PARAMETER LIPID DARAH MENCIT HIPERKOLESTEROLEMIA DENGAN SUPLEMEN PANGAN BEKATUL Hernawati, -; Manalu, Wasmen; Suprayogi, Agik; Astuti, Dewi Apri
Majalah Kedokteran Bandung Vol 45, No 1 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Serat pangan telah banyak digunakan sebagai pangan fungsional dan direkomendasikan untuk menurunkan kadar lipid darah untuk mencegah hiperkolesterolemia. Bekatul merupakan bahan pangan yang mengandung serat cukup tinggi. Tujuan penelitian untuk mempelajari pengaruh penambahan bekatul pada parameter lipid darah mencit jantan hiperkolesterolemia. Penelitian dilakukan di kandang hewan Jurusan Pendidikan Biologi Universitas Pendidikan Indonesia dan Laboratorium Fisiologi Fakultas Kedokteran Hewan Institut Pertanian Bogor periode Agustus 2011?Maret 2012. Desain penelitian menggunakan rancangan acak lengkap dengan lima kelompok perlakuan, yaitu kontrol negatif mencit normokolesterolemia yang diberi pakan standar tanpa suplementasi bekatul dan kontrol positif mencit hiperkolesterolemia tanpa suplementasi bekatul, selanjutnya kelompok mencit hiperkolesterolemia diberi suplementasi bekatul 16%, 38%, dan 57%. Parameter yang diukur ialah bobot badan, konsentrasi kolesterol total serum, hati, dan feses, kadar trigliserida, high density lipoprotein (HDL-c), low density lipoprotein (LDL-c), dan glukosa darah. Hasil penelitian menunjukkan bahwa suplementasi bekatul dalam diet menurunkan bobot badan, konsentrasi kolesterol serum total dan hati, trigliserida dan LDL-c, serta menaikkan konsentrasi HDL-c dan kolesterol feses, tanpa mengubah konsentrasi glukosa darah. Suplementasi bekatul sebesar 57% menurunkan bobot badan sebesar 10,31%, kadar total kolesterol 17,28%, trigliserida 28,63%, dan LDL-c 79,35%, serta meningkatkan HDL-c sebesar 24,41%. Suplementasi bekatul menurunkan kolesterol hati 57,76% dan meningkatkan pembuangan kolesterol melalui feses sebesar 39,86%. Simpulan, bekatul sebagai suplemen makanan memperbaiki parameter lipida darah mencit jantan hiperkolesterolemia dengan meningkatkan pembuangan kolesterol melalui feses dan menurunkan bobot badan tanpa mengubah kadar glukosa darah [MKB. 2013;45(1):1?9]Kata kunci: Bekatul, hiperkolesterolemia, lipid darah, mencit, serat pangan Improvement of Blood Lipid Parameters of Hypercholesterolemic Mice by Supplementation of Rice BranDietary fiber is widely used as a functional food and recommended to reduce blood lipid level to prevent hypercholesterolemia. An experiment was conducted on the effects of rice bran that has high dietary fiber content on blood lipid parameters of hypercholesterolemic male mice, which was conducted at the Biology Education Department animal cages, Indonesia University of Education and the Veterinary Medicine Faculty Laboratory, Bogor Agricultural Institute from August 2011 to March 2012. The mice were randomly assigned into groups with 5 different treatments: negative control group i.e. normocholesterol mice with a standard diet without rice bran; positive control group i.e. hypercholesterolemic mice with a standard diet without rice bran; and groups with hypercholesterolemic mice with 16%, 38%, and 75% rice bran supplements. The parameters were body weight as well as blood serum, liver and feces cholesterol, triglyceride, high density lipoprotein (HDL-c), low density lipoprotein (LDL-c) and glucose levels. Body weight, blood serum and liver cholesterol as well as triglyceride and LDL concentrations decreased while serum HDL-c and feces cholesterol increased without any significant effect on blood glucose concentration with rice bran supplement. Supplementation of rice bran by 57% (14.30% of nonsoluble dietary fiber content) decreased body weight, total serum cholesterol, triglyceride, and LDL-c of 10.31%, 17.28%, 28.63%, and 79.35%, respectively, and increased HDL-c by 24.41%. Rice bran supplement reduced liver cholesterol levels by 57.76% and increased fecal cholesterol excretion by 39.68%. In conclusion, 57% rice bran supplementation is effective to improve blood lipid parameters of hypercholesterolemic male mice by increasing feces excretion and decreasing body weight with no change in blood glucose level. [MKB. 2013;45(1):1?9]Key words: Blood lipid, dietary fiber, hypercholesterolemia, mice, rice bra DOI: http://dx.doi.org/10.15395/mkb.v45n1.93

Physiological Value of Heart Rate, Respiration and Rectal Temperature of Wild-Captive Dugong (Dugong dugon)–A Case Study in Lingayan Island Aryani Sismin Satyaningtijas; Agik Suprayogi; Ardiansyah Nurdin; Huda S. Darusman
HAYATI Journal of Biosciences Vol. 26 No. 4 (2019): October 2019
Publisher : Bogor Agricultural University, Indonesia

This study aims to obtain the physiological value of dugongs that live in natural habitats (in-situ) as protected wildlife, namely on the coast of Lingayan Island, Toli-Toli Regency. Wild dugongs caught on the beach were put into a net cage. After 14 days of living in a beach cage, measurements of heart rate, respiration, and body temperature were measured using non-invasive methods. This study showed that the value of heart rate, respiration, and body temperature were measured (80.00±17.32) beats/minutes, (17.33±6.80) inspiration/minute, and (32.75±0.07)°C. This physiological value is higher when compared to dugongs that live in captivity, this is likely due to the process of homeostasis through physiological adaptation mechanisms. The physiological value of the dugong is very important for the advancement of dugong animal health science and technology. Besides this finding can be a medical reference that is very useful for veterinarians in the diagnostic and therapeutic process.

Dinamika profil hematologi dan rasio netrofil:limfosit monyet ekor panjang (Macaca fascicularis) pada pengaturan mikroklimat ruangan Ridzki M.F. Binol; Agik Suprayogi; Huda S. Darusman
Jurnal Ilmu Pertanian Indonesia Vol. 15 No. 2 (2010): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

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The aim of this study was to obtain the profile of physiological hematology (erythrocyte, PCV, Hb, MCV, MCH, MCHC, and leukocyte) and the profile of ratio between neutrophil and lymphocyte of long-tailed macaque (Macaca fascicularis) in different microclimate conditions due to the room's temperature and humidity setting. The symptom of stress was also observed in this study. The research used 10 male macaques aged of 4 until 5 years old which placed in room temperature and humidity of 29,00±1,95°C and 79,52±1,57% respectively 7 days for adaptation period. Further more, the room temperature and humidity were set into 25,79±1,16°C and 80,19±9,05°/o during 14 days for treatment period. For the last treatment, macaques were reconditioned in room temperature and humidity of 29,00±1,95°( and 79,52±1,57°/o during 14 days for post-treatment period. Blood samplings were collected through femoralis vein on last day of adaptation period, continued with treatment and post-treatment periods as the day 1, 4, 7, 14, and 28. The results showed that there were not significant difference by room temperature and humidity setting to hematology and neutrophil: lymphocyte ratio. It could be proven by all parameters score obtained were still in normal ranges compared to literatures. There was also no stress symptom based on neutrophil:lymphocyte ratio measurement. Condition with room temperature and humidity of 25,79±1,16°C dan 80,19±9,05% regarded as the most suitable condition for long-tailed macaque'slife.

Perbandingan nilai fisiologis kardiorespirasi dan suhu rektal anjing kampung dewasa dan anak Agik Suprayogi; Huda S. Darusman; Iqbal Ngabdusani
Jurnal Ilmu Pertanian Indonesia Vol. 14 No. 3 (2009): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

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Dog is man's favorite companion animal and they are also beneficial as an animal model in biomedical research. So far, the Indonesian native dog's physiological values for diagnostic or research purposes, was based on literature which differed in breeds, geography and age variety. Furthermore, there is little publication on Indonesian native's dog physiological value which emphasize on its age variety, specially its comparative study between adult and puppies. Comparative parameters which were used in this study were heart rate {HR), respiratory rate {RR), non-invasive blood pressure {NIBP) and rectal temperature {RT). The study utilized fifteen Indonesian native dogs. The result showed a significant {p< 0.05) higher HR's values on puppies to adult, which are 152.50±14.76 and 95.93±23.7 beat per minute), respectively, while the RT's were lower on puppies to adults {37.53±0.29 and 38.23±0.73 °C, respectively). The NIBP's values were significantly lower on puppies to adult, which are systole {83.93±13.29 Vs 129.68±24.45 mmHg), diastole {37.50±16.31 Vs 72.96±20.33 mmHg) and mean blood pressure values {58.21±13.30 Vs 91.82±24.34 mmHg). The insignificant result was found on RR values which are 26.50±7.93 and 28.21±14.34 for puppies and adult, respectively. The main reason for the differences in above parameters among puppies and adult can be defined by their metabolic rate and growth process.

Peningkatan Produksi Susu Sapi Perah di Peternakan Rakyat Melalui Pemberian Katuk-IPB3 sebagai Aditif Pakan Agik Suprayogi; Hadri Latif; . Yudi; Asep Yayan Ruhyana
Jurnal Ilmu Pertanian Indonesia Vol. 18 No. 3 (2013): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

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This study was to evaluate the depolarization of katuk leaves (Katuk-IPB3) as a feed additive for increasing dairy cattle milk yield at the farmer condition. Sixteen selected lactating cattles were divided into 4 groups; 4 cattles in each group. One group as a control, and 3 treated groups, namely P100, P150, and P200. P100, P200, and P300 were designated as cattle group given powder of Katuk-IPB3 as much as 100 g/day, 150 g/day, and 200 g/day, respectively. The treatment was executed in the 10 days before pregnancy up to 2 months lactating periods. Katuk-IPB3 showed significant positive response on the produced milk on all dose levels as compared to the control group, i.e. 35, 40, and 34% increased, respectively. The possible reason is that the nonpolar active compounds in the Katuk-IPB3 play an important role to the hormonal and metabolic action in the lactating mammary gland.

Nilai Hematologi, Denyut Jantung, Frekuensi Respirasi, dan Suhu Tubuh Ternak Sapi Perah Laktasi di Pangalengan Agik Suprayogi; Ganjar Alaydrussani; Asep Yayan Ruhyana
Jurnal Ilmu Pertanian Indonesia Vol. 22 No. 2 (2017): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Pangalengan is located in the high land region with an altitude of 1.000-1.420 m above sea level, which has an average temperature of 17.80 ± 1.46 0C and humidity of 63.99 ± 2.74%. These environmental conditions will affect the physiological values of dairy cattle, especially during the lactation period. However, information about the physiological parameters of lactating cows in this area is not available. This study used 20 lactating dairy cows, and physiological values were measured in the morning, midday, and afternoon. The ranges of heart rate, respiration rate, and rectal temperature of dairy cows during lactation period were 59.82-72.02 times/min, 26.01-36.69 times/min, and 37.32-38.36 0C, respectively. The range of hemoglobin, hematocrit, erythrocytes, and leukocytes of lactating dairy cows was 8.29-9.51 g/dl, 24.52-29.70%, 6.10-8.18 million/µl, and 6.220-10.600 cells/µl, respectively. The range of differential leukocyte of lactating dairy cows were lymphocyte 32.64-63.14%, neutrophils 28.34-53.24%, monocytes 0.41-4.85%, eosinophils 1.58-15.78%, and basophils 0%, respectively. The range of a ratio of N/L of lactating dairy cows was 0.41-1.63. This study concludes that lactating dairy cows maintained under mild Pangalengan climatic conditions still show physiological values within the normal range

Nilai Fisiologis Sapi Perah Kering Kandang di Pangalengan: Hematologi, Denyut Jantung, Frekuensi Respirasi, dan Suhu Tubuh Agik Suprayogi; Khairul Ihsan; Asep Yayan Ruhyana
Jurnal Ilmu Pertanian Indonesia Vol. 24 No. 4 (2019): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Pangalengan is at an altitude of 1000-1400 m above sea level with annual temperatures range of 12-28°C and annual humidity of 60-70%. Pangalengan's environmental conditions can affect the physiological conditions and health of dairy cattle, especially during the dry period. The information about the physiological value of dairy cows when they are in a dry period is not yet available. This study used 46 dairy cows that were on a dry period, and measurements of physiological parameters were carried out in the morning, afternoon, and evening. Heart rate, respiration rate, and body temperature ranges were 52,8-70,2 times/min, 18.9−36.6 times/min, and 37,6-38,6°C, respectively. The ranges of hemoglobin, hematocrit, erythrocytes, and leukocytes were 9.3-11.3 g/dl; 30.4-36.6%; 6.5-8.70 million/µl; and 7.4-12.8 thousand/µl, respectively. The differential ranges of leukocytes including lymphocytes, neutrophils, monocytes, eosinophil, and basophils were at 29.60-55.60%; 28.80-56.20%; 0.30-4.30%; 5.50-19.7%; and 0.00-0.00%, respectively. The neutrophil/lymphocyte ratio was obtained in the range of 0.45-1.91. This study concluded that dairy cows during dry period maintained in mild Pangalengan climatic conditions showed physiological values that were within the normal range.

Produksi dan Kualitas Kolostrum dan Susu Kolostrum pada Sapi Perah yang Mengkonsumsi Daun Katuk Depolarisasi Afton Atabany; Agik Suprayogi; Muladno Muladno; Fadjar Satrija; Ronald Tarigan; Welly Sugiono; Yuliantony Queen
Jurnal Ilmu Pertanian Indonesia Vol. 27 No. 2 (2022): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18343/jipi.27.2.263

This study aims to determine the effect of additional feed with depolarizing katuk leaves on the production and quality of colostrum and colostrum milk in Friesian Holstein dairy cows. There were 21 dairy cows that had just giving birth, divided into 3 groups of 7 each, namely the control group (complete feed), BKD (complete feed added with Depolarizing Katuk Powder), PKD (complete feed added with Depolarizing Katuk Pellet). Depolarizing katuk feed was given 100 grams per head per day as a feed additive. Parameters observed were feed consumption, production and quality of colostrum and colostrum milk. The results showed that there was no difference in the consumption of feed supplemented with depolarizing katuk leaves, colostrum production, milk density, total solid colostrum, Solid non-fat, lactose contents, and protein contents of colostrum and colostrum milk compared to the control group. Significant differences occurred in colostrum milk production, total solid colostrum milk, and fat content of colostrum and colostrum milk. It was concluded that depolarizing katuk leaves could be used as additional feed to increase the production and total solids of colostrum milk, and increase the fat content of colostrum and colostrum milk. Keywords: colostrum, colostrum milk, depolarizing katuk leaf, Friesian Holstein

Co-Authors , Triadiati - Hernawati . Prastowo . Priyanto . Yudi A.S. Satyaningtijas Achmad Tjahja Afton Atabany Ahmad Tjahja Nugraha, Ahmad Tjahja Amrozi Andi Novita Aprilyana, Lia Ardiansyah Nurdin Ardilasunu Wicaksono Arifin B. Nugraha Arni Fitri Aryani Satyaningtijas Asep Yayan Ruhyana Asep Yayan Ruhyana Aswani, Tuti Damiana Rita Ekastuti Dede Sukandar Deni Noviana DEWI APRI ASTUTI Dewi Ratih Agungpriyono Dewi, Farida Ratna Edi Santosa Elsi Ramadhani Fachruddin Fachruddin Fadjar Satrija Ganjar Alaydrussani Gunanti . Hadri Latif Hajar Hajar Hamdani Budiman HERA MAHESHWARI Hernawati Hernawati Herwin Pisestyani Hidayaturrahmah Hidayaturrahmah Huda Salahuddin Darusman Huda Shalahudin Darusman I Gusti Agung Ayu Suartini I Gusti Ngurah Kade Mahardika I wayan Teguh Wibawan Ika Amalia, Ika Indah Wijayanti Indrawati Sendow Iqbal Ngabdusani Ira Agustina Dewi Gandasari Irfan Nurhidayat Isdoni Bustaman Jannatun Delvia Juang Gema Kartika Juli Melia Katrin Roosita Khairul Ihsan koekoeh santoso Koekoeh Santoso Koekoeh Santoso Kudang Boro Seminar Kukuh Santoso L. M. Saniwu La Ode Sumarlin La Ode Sumarlin Linda Tjhin Lynette Ong Huey Megawati Iskandar Meyliana Wulandari Mokhamad Fakhrul Ulum, Mokhamad Muhammad Ardiansyah Nurdin Muladno - Muslim Akmal Nastiti Kusumorini NASTITI KUSUMORINI Nelda Fliza Zora Ni Luh Putu Agustini Nofriyandi Hanif Novriyandi Hanif Pudji Achmadi Putri, Maritrana Rahmat Hidayat Rahminiwati, Min Razali R Ridi Arif Ridzki M.F. Binol Rika Sudranto Riki Siswandi Rina Aulia Barus Ritonga, Arya Widura Rivangga Yuda Hendika Ronald Tarigan Ronald Tarigan Ronald Tarigan Sattabongkoch Maneewong Saukhan, Ghiandra Naufal Syazily Sri Darwati sri murtini . Sri Supraptini Mansjoer Sri Wahyuni Sulistyaningsih, Yohana Caecilia Sumiaty Aiba Sumitro - Suryahadi (Suryahadi) Syaprianti Evi Dame Arita Tampubolon, Andre Rymma Tarigan, Ronald Teuku Reza Ferasyi Tuti Aswani Umi Cahyaningsih Wasmen Manalu Welly Sugiono Welly Sugiono Yasinta Ratna Esti Wulandari Yohana Caecilia Sulistyaningsih Yuliantoni Queen Yuliantoni Yuliantoni Yuliantony Queen Zulvia Maika Letis

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