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INDONESIA
Jurnal Farmasi Klinik Indonesia
Published by Universitas Padjadjaran
ISSN : 23375701     EISSN : 2337 5701     DOI : -
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Indonesian Journal of Clinical Pharmacy (IJCP) is a scientific publication on all aspect of clinical pharmacy. It published 4 times a year by Clinical Pharmacy Master Program Universitas Padjadjaran to provide a forum for clinicians, pharmacists, and other healthcare professionals to share best practice, encouraging networking and a more collaborative approach in patient care. Indonesian Journal of Clinical Pharmacy is intended to feature quality research articles in clinical pharmacy to become scientific guide in fields related to clinical pharmacy. It is a peer-reviewed journal and publishes original research articles, review articles, case reports, commentaries, and brief research communications on all aspects of Clinical Pharmacy. It is also a media for publicizing meetings and news relating to advances in Clinical Pharmacy in the regions.
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Articles 540 Documents
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Quality of Life and Adherence of Diabetic Patients in Different Treatment Regimens Perwitasari, Dyah A.; Adikusuma, Wirawan; Rikifani, Shoma; Supadmi, Woro; Kaptein, Adrian A.
Indonesian Journal of Clinical Pharmacy Vol 3, No 4 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1165.779 KB) | DOI: 10.15416/ijcp.2014.3.4.107

Abstract

The diabetic patient’s quality of life and adherence should be a concerned by health care providers. This study aimed to explore the diabetic patient’s quality of life and medication adherence into account. We recruited 88 subjects in a cross-sectional design. The research subjects were out-patients with type 2 diabetes mellitus in a private hospitals in Yogyakarta City who had taken single or combination of oral anti diabetic and insulin at least six months prior to quality of life measurement. Patients were classified into three groups (monotherapy, oral combination therapy, and oral-insulin combination group). The domains of physical function, energy, satisfaction treatment, and treatment effect were significantly different among the three groups. There were significant associations between treatment satisfaction domain and adherence in monotherapy and oral-insulin combination groups, the health pressure domain and adherence in oral-insulin combination group, the treatment satisfaction domain with adherence in first two groups, and health pressure domain with adherence in oral-insulin combination group. In conclusion, the quality of life of the diabetic patients was good and their medication adherence was at a moderate level.Key words: Adherence, diabetes, Indonesia, quality of life Kualitas Hidup dan Kepatuhan Pasien Diabetes Melitus dengan Pengobatan yang BerbedaKualitas hidup dan kepatuhan pasien diabetes melitus (DM) sebaiknya mendapat perhatian dari pemberilayanan kesehatan. Penelitian ini bertujuan untuk mengetahui kualitas hidup pasien DM dan hubungannya dengan kepatuhan pasien. Penelitian ini dilakukan dengan menggunakan rancangan potong lintang. Subjek penelitian ini adalah 88 orang pasien DM tipe 2 di suatu rumah sakit swasta di Yogyakarta yang memperoleh pengobatan baik tunggal maupun kombinasi antara antidiabetes oral dan insulin minimal enam bulan sebelum pengambilan data kualitas hidup. Pasien dikategorikan menjadi tiga kelompok, yaitu kelompok monoterapi, kombinasi oral antidiabetes, dan kombinasi oral-insulin. Terdapat perbedaan yang signifikan antara ketiga kelompok ini pada domain fungsi fisik, energi, kepuasan terhadap terapi, dan efek pengobatan. Terdapat hubungan signifikan antara domain kepuasan pasien dengan kepatuhan pada kelompok monoterapi dan terapi kombinasi oral, domain tekanan kesehatan dengan kepatuhan pada kelompok terapi kombinasi oral-insulin, serta domain kepuasan pasien dan tekanan kesehatan dengan kepatuhan pasien pada ketiga kelompok terapi. Kualitas hidup pasien DM pada penelitian ini cukup bagus dengan kepatuhan pada tingkat moderat.Kata kunci: Diabetes, kepatuhan, kualitas hidup, Indonesia
Artikel Penelitian Pengaruh Pendampingan Apoteker Saat Visite Dokter terhadap Kesalahan Peresepan di Ruang Perawatan Intensif Turnodihardjo, Marlina A.; Hakim, Lukman; Kartikawatiningsih, Dewi
Indonesian Journal of Clinical Pharmacy Vol 5, No 3 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (531.466 KB) | DOI: 10.15416/ijcp.2016.5.3.160

Abstract

Saat ini keselamatan pasien (patient safety) menjadi isu penting dalam pelayanan farmasi karena tidak dapat dipungkiri bahwa kesalahan pengobatan kerap terjadi di rumah sakit. Kesalahan pengobatan yang sering terjadi adalah kesalahan peresepan yang merupakan tahap awal proses pelayanan farmasi. Kesalahan peresepan berpotensi fatal bila terjadi di ruang perawatan intensif disebabkan karena kondisi pasien yang kritis, banyak komplikasi dan polifarmasi. Salah satu upaya pencegahan kesalahan peresepan adalah dengan pendampingan apoteker di ruang perawatan. Tujuan penelitian untuk mengetahui pengaruh pendampingan apoteker saat visite dokter terhadap kesalahan peresepan di ruang perawatan intensif. Penelitian ini adalah penelitian kuasi eksperimental dengan desain one group pre-post test. Pengambilan data secara prospektif dilakukan selama bulan April–Mei 2015 terhadap 110 sampel resep. Skrining resep dilakukan apoteker depo untuk mencatat kesalahan peresepan pada lembar observasi. Kesalahan peresepan didefinisikan sebagai kesalahan dalam proses penulisan resep. Kesalahan penulisan yang dimaksud adalah informasi resep yang tidak lengkap/tidak ditulis dan informasi resep yang tidak sesuai kesepakatan. Analisa perbedaan kesalahan peresepan sebelum dan dengan pendampingan apoteker menggunakan uji Mann-Whitney. Hasil penelitian menunjukkan bahwa ada perbedaan bermakna antara kesalahan peresepan sebelum dan dengan pendampingan apoteker (p<0,05). Juga terdapat korelasi negatif yang bermakna antara frekuensi rekomendasi pendampingan apoteker dan frekuensi kesalahan peresepan (r= –0,638; p<0,05). Artinya kegiatan pendampingan apoteker perlu ditingkatkan sebagai awalan implementasi farmasi klinik dan proses kolaborasi antara dokter dan apoteker. Hal tersebut tentu saja membutuhkan dukungan sistem manajemen rumah sakit agar komunikasi interpersonal diantara profesi lebih mudah terwujud.Kata kunci: Farmasi klinik, kesalahan peresepan, one group pre-post test, pendampingan apoteker Effect of Pharmacist Participation During Physician Rounds and Prescription Error in the Intensive Care Unit  Patient’s safety is now a prominent issue in pharmaceutical care because of adverse drug events that is common in hospitalized patients. Majority of error are likely occured during prescribing, which is the first stage of pharmacy process. Prescription errors mostly occured in an Intensive Care Unit (ICU), which is due to the severity of the illness of its patients as well as the large number of medications prescribed. Pharmacist participation actually could reduce prescribing error made by doctors. The main objective of this study was to determine the effect of pharmacist participation during physician rounds on prescription errors in the ICU. This study was a quasi-experimental design with one group pre-post test. A prospective study was conducted from April to May 2015 by screening 110 samples of orders. Screening was done to identify type of prescription errors. Prescription error was defined as error in the prescription writing process – incomplete information and not according to agreement. Mann-Whitney test was used to analyze the differences in prescribing errors. The results showed that there was the differences between prescription errors before and during the pharmacist participation (p<0.05). There was also a significant negative correlation between the frequency of pharmacist recommendation on drug ordering and prescription errors (r= –0.638; p<0.05). It means the pharmacist participation was one of the strategies that can be adopted to prevent in prescribing errors and implementation of collaboration between both doctors and pharmacists. In other words, the supporting hospital management system which would encourage interpersonal communication among health care proffesionals is needed.Keywords: Clinical pharmacist, one group pre-post test, pharmacist participation, prescription errors
Korelasi Faktor Usia, Cara Minum, dan Dosis Obat Metformin terhadap Risiko Efek Samping pada Penderita Diabetes Melitus Tipe 2 Riwu, Magdarita; Subarnas, Anas; Lestari, Keri
Indonesian Journal of Clinical Pharmacy Vol 4, No 3 (2015)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (324.662 KB) | DOI: 10.15416/ijcp.2015.4.3.151

Abstract

Metformin merupakan obat antidiabetes oral yang umumnya direkomendasikan sebagai pengobatan lini pertama pada diabetes melitus tipe 2 apabila kadar glukosa darah tidak terkontrol dengan modifikasi gaya hidup. Pada penggunaan metformin sebagai kontrol glikemia sering terjadi reaksi obat yang merugikan (ROM) berupa gangguan gastrointestinal seperti diare, mual, dan perut kembung. Penelitian ini bertujuan untuk menganalisis korelasi faktor usia, cara minum, dan dosis metformin terhadap risiko efek samping gangguan gastrointestinal pada penderita rawat jalan BPJS Kesehatan yang baru terdiagnosis diabetes melitus tipe 2 di RSAU Dr. M. Salamun Bandung. Penelitian ini adalah analitik observasional dengan desain potong lintang. Data dikumpulkan dari bagian poliklinik penyakit dalam, rekam medis, dan form check penderita yang mendapat pengobatan dengan metformin yang dilakukan sejak April–Juni 2014. Jumlah penderita yang memenuhi kriteria penelitian sebanyak 65 orang dengan rentang usia rata-rata 48 tahun. Keluhan efek samping yang dialami penderita berupa kembung (58,46%) dan mual (41,54%). Cara minum dan dosis metformin berkorelasi terhadap risiko efek samping berupa mual dan kembung pada penderita diabetes melitus tipe 2 (p<0,05) sedangkan faktor usia tidak berkorelasi (p>0,05). Penggunaan metformin dianjurkan sesudah makan dan dengan dosis awal rendah yang dititrasi perlahan untuk mengurangi dan menghindari terjadinya efek samping mual dan perut kembung pada penderita diabetes melitus tipe 2.Kata kunci: Diabetes melitus tipe 2, efek samping, metforminThe Correlation of Age Factor, Administration, and Metformin Dose Against Risk of Side Effect on Type 2 Diabetes MellitusMetformin is an antidiabetic oral medicine commonly recommended as first line treatment on type 2 diabetes mellitus. Metformin can caused drug related problems (DRPs) such as gastrointestinal disorders, e.g. diarrhea, nausea, and flatulence. This study aimed to analyze correlation profiles on age, administration, and metformin dosage factors against risk of gastrointestinal disorders among newlydiagnosed diabetic outpatients of National Health Insurance in RSAU Dr. M. Salamun Bandung. This study was an analytic observational study with a cross sectional method. The study was carried out in the internal medicine outpatient clinic and data were extracted from patients medical records from April to June 2014. Metformin-treated patients were interviewed using a form check. The number of patients were 65 with the median rate was 48 years old. Side effect reported were flatulence (58.46%) and nausea (41.54%). Administration and metformin dosage factors were correlated to the risk of side effects such as nausea and flatulence on type 2 diabetes mellitus (p<0.05), while age was not correlated (p>0.05). The administration of metformin is recommended after meals and with a lower initial dose titrated slowly to reduce and avoid the side effects of nausea and flatulence in patients with type 2 diabetes mellitus.Keywords: Metformin, side effect, type 2 diabetes mellitus
Evaluasi Penggunaan dan Efektivitas Antibiotik Profilaksis pada Pasien Bedah Sesar di Rumah Sakit Surakarta Tahun 2010 Mutmainah, Nurul; Setyati, Puri; Handasari, Niken
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.399 KB) | DOI: 10.15416/ijcp.2014.3.2.44

Abstract

Penggunaan antibiotik profilaksis pada operasi bedah sesar dapat mengurangi risiko infeksi yangberhubungan dengan komplikasi dan infeksi pascaoperasi. Penelitian ini bertujuan untuk mengetahuigambaran dan ketepatan penggunaan serta efektivitas antibiotik profilaksis pada pasien bedah sesar padadua rumah sakit di Surakarta tahun 2010. Penelitian ini termasuk penelitian deskriptif dengan pengambilandata rekam medis secara retrospektif. Analisis dilakukan terhadap penggunaan antibiotik yang meliputiketepatan antibiotik dibandingkan dengan ketepatan dosis dan  waktu pemberian berdasarkan standar WHO. Sebanyak 200 pasien yang diteliti, ditemukan 76% berusia 20–35 tahun, usia kehamilan sudah cukup bulan (90,5%), lama perawatan di rumah sakit lebih dari 5 hari (46,5%), dan indikasi terbanyakbedah sesar adalah ketuban pecah dini (29%). Antibiotik profilaksis yang digunakan adalah ampisilin(24%), ampisilin-sulbaktam (23%), seftriakson (19,5%), sefotaksim (16%), amoksisilin-klavulanat(11%), dan  sefazolin (6,5%). Ditemukan kesesuaian pemilihan obat dengan standar WHO (30,5%),yang meliputi tepat dosis (6,5%) dan tepat waktu pemberian (52%). Penggunaan antibiotik 100% efektifuntuk mencegah luka infeksi setelah operasi.   Kata kunci: Antibiotik, bedah sesar, profilaksisEvaluation of the Use and Effectiveness of Antibiotics for Prophylactic inPatients with Cesarean Section  at Hospitals in Surakarta in 2010AbstractThe use of antibiotics for prophylactic in sectio cesarean can reduce the risk of infection-relatedcomplications and postoperative infections. This study aims to describe and evaluate the usage  and theeffectiveness of prophylactic antibiotics in cesarean section  patients in two hospitals in Surakarta inyear 2010. The study used retrospective data from medical records. The analysis was then conducted onthe use of antibiotic including the appropriateness of antibiotic (compare to the standard of WHO), theappropriateness of dose and the time of administration. The data from two hundred of patients  showedthat 76% of patients were between 20–35 years old and the patients with aterm pregnancy were 90.5%,46.5% of patients had the length of stay in hospital more than 5 days and 29% of cesarean deliveryindicated by amniotic premature rupture. Antibiotics that used for prophylactic were ampicillin (24%),ampicillin-sulbactam (23%), ceftriaxone (19.5%), cefotaxime (16%), amoxicillin-clavulanate (11%),and cefazolin (6.5%). It was found that 30,5% of drugs were selected based on standard,  6.5% of drugswere given in the appropriate  dose and 52% of drugs were administrated on-time. In conclusion, theantibiotics are 100% effective to prevent the incidence of surgical wound infection.Key words: Antibiotics, cesarean section, prophylactic
Peran Kepemimpinan dan Employee Engagement terhadap Kinerja Individual Karyawan Instalasi Farmasi Rahayu, Susi A.; Surahman, Emma
Indonesian Journal of Clinical Pharmacy Vol 1, No 3 (2012)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (611.444 KB)

Abstract

Ketidakpuasan karyawan terhadap kepala instalasi dapat menyebabkan kinerja karyawan menurun dan ketidakpuasan pelanggan. Salah satu cara  meningkatkan kinerja karyawan adalah denganmerasa terikat terhadap pekerjaannya (employee engagement). Salah satu faktor untuk meningkatkanemployee engagement adalah faktor kepemimpinan. Oleh karena itu, perlu dilakukan penelitian mengenai pengaruh kepemimpinan terhadap kinerja individual karyawan instalasi farmasi rumah sakit serta pengaruh employee engagement sebagai mediator. Sebanyak 79 karyawan instalasi farmasi dari dua rumah sakit swasta di Kota Bandung menjadi partisipan. Penelitian ini menggunakan teknik partial least square untuk menguji hubungan hipotesis. Hasil penelitian menunjukkan terdapat signifikansi antara kepemimpinan terhadap employee engagement (t value (12,84) > t-tabel (1,64)), signifikansi employee engagement terhadap kinerja individual (t value (3,83) > t-tabel (1,64)). Kepemimpinan terhadap kinerja individual (t value (0,45) < t-tabel (1,64)) tidak terdapat pengaruh dan signifikansinya. Employee engagement memediasi hubungan antara kepemimpinan dan kinerja individual.Kata kunci: Kepemimpinan, employee engagement, kinerja individual Role of Leadership and Employee Engagement towards Individual Performance of Pharmacy EmployeesAbstractEmployees dissatisfaction to the head of the hospital pharmacy will decrease employees performanceand unsatisfied customers. To solve the problems, employees should be based on performance as customer expectations in providing services. One of the ways to improve the performance of the employees, they must feel engage to the work. One of the factors to improve employee engagement isthe leadership factor. Therefore, it is necessary to study the impact of leadership on individual performance employee in hospital pharmacy and also the influence of employee engagement as a mediator. A total of 79 employees from the pharmacy in two private hospitals in Bandung became theparticipants. This study used the technique of partial least squares to test the hypothesized relationships.The results showed that there were significant between leadership to employee engagement (t value (12,84) > t-table (1.64)), the significance of employee engagement on individual performance (t value (3.83) > t-table (1.64)). In contrast, there was no influence and significance in leadership on individual performance (t value (0.45) < t-table (1.64)). Employee engagement fully mediated the relationshipbetween leadership and individual performance. Therefore, improving pharmacy services is a set of actions and involvement of pharmacy employees who are consistent, sustainable and clear. Key words: Leadership, employee engagement, individual performance
Pengaruh Pemberian Steroid sebagai Terapi Tambahan terhadap Rata-Rata Lama Pasien Dirawat di Rumah Sakit dan Tanda Klinis pada Anak dengan Pneumonia Ardyati, Sulistia; Kurniawan, Nurcholid U.; Darmawan, Endang
Indonesian Journal of Clinical Pharmacy Vol 6, No 3 (2017)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (604.648 KB) | DOI: 10.15416/ijcp.2017.6.3.181

Abstract

Terapi steroid pada anak dengan pneumonia merupakan terapi tambahan yang memiliki aktivitas sebagai penghambat inflamasi yang menekan ekspresi sitokin proinflamasi dan berpotensi mencegah respon inflamasi. Beberapa penelitian menunjukkan pemberian steroid tidak memberikan pengaruh dalam pengobatan pada pasien pneumonia, tetapi pada penelitian lain menunjukkan pemberian steroid mengurangi rata-rata lamanya pasien dirawat di rumah sakit. Tujuan dari penelitian ini adalah untuk melihat pengaruh pemberian steroid terhadap rata-rata lamanya pasien dirawat di rumah sakit (LoS) dan tanda klinis pasien anak dengan pneumonia. Penelitian yang dilakukan merupakan penelitian observasional dengan metode prospektif yang dilakukan di Rumah Sakit PKU Muhammadiyah Bantul Yogyakarta pada bulan September 2015 hingga Januari 2016. Lima puluh satu pasien digunakan sebagai subjek penelitian. Penelitian ini terdiri dari 2 kelompok yakni kelompok non-steroid terdiri dari 25 pasien dan kelompok steroid terdiri dari 26 pasien. Kelompok non-steroid dan steroid masing-masing memiliki nilai rata-rata lamanya pasien dirawat di rumah sakit 5 (3–10) hari dan 4 (3–10) hari. Durasi tanda klinis pasien kelompok steroid dan kelompok non-steroid berturut-turut adalah 2 (0–6) hari dan 2 (0–7) hari untuk demam, batuk 4 (1–10) hari dan 5 (2–10) hari, sesak 1 (0–5) hari dan 1 (0–10) hari, retraksi 1 (0–5) hari dan 1 (0–9) hari. Kesimpulan dari penelitian ini adalah steroid sebagai terapi tambahan memberikan efek yang tidak berbeda bermakna terhadap nilai length of stay dan tanda klinis pasien anak dengan pneumonia.Kata kunci: Anak, length of stay, pneumonia, steroid Steroids Effect as Adjuvant Therapy toward Length of Stay and Clinical Symptoms in Pediatric with PneumoniaSteroid therapy in children with pneumonia is an adjuvant therapy that has inhibitor inflammatory activity which can suppress the expression of proinflammatory cytokines and potentially prevent the inflammatory response. Some studies showed that steroids did not give beneficial effects in the treatment of patients with pneumonia, while the other studies showed that steroids can reduce the length of stay in hospital. The purpose of this study was to observe the effect of steroid on the length of stay and clinical symptoms in pediatric patients with pneumonia. This was an observational study with a prospective method in patients with pneumonia in PKU Muhammadiyah Bantul Hospital Yogyakarta from September 2015 until January 2016. Fifty one patients participated as subjects of this study. This study consisted of two groups, which were non-steroid group (n=25) and steroid group (n=26). Group of non-steroid and steroid had average value of length of stay of 5 (3–10) days and 4 (3–10) days, respectively. The duration of clinical symptoms of patients in the steroid and non-steroid group in a row was 2 (0–6) days and 2 (0–7) days for symptoms of fever, 4 (1–10) days and 5 (2–10) days for symptoms of cough, 1 (0–5) days and 1 (0–10) days for symptoms of shortness, and 1 (0–5) days and 1 (0–9) days for symptoms of retraction. The conclusion of this study is steroid has not given significant effects on the length of stay and clinical symptoms in pediatric patients with pneumonia.Keywords: Length of stay, pediatric, pneumonia, steroid
Evaluasi Penggunaan Antibiotik pada Pasien Bedah di Suatu Rumah Sakit Swasta di Bandung Zazuli, Zulfan; Sukandar, Elin Y.; Lisni, Ida
Indonesian Journal of Clinical Pharmacy Vol 4, No 2 (2015)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2015.4.2.87

Abstract

Pemberian antibiotik prabedah dan pascabedah telah digunakan secara luas untuk menghindari dan menangani infeksi pada daerah pembedahan. Penggunaan antibiotik harus dievaluasi melalui program evaluasi penggunaan obat (EPO) untuk  menjamin penggunaan obat yang rasional. EPO antibiotik ini dilakukan berdasarkan pada kriteria penggunaan obat yang telah ditetapkan menggunakan studi data retrospektif dari bulan September sampai dengan November tahun 2009 untuk seluruh pasien bedah di salah satu rumah sakit swasta di Bandung. Telah dilakukan pemberian antibiotik sebanyak 1290 dosis yang terdiri atas pemberian antibiotik prabedah sebanyak 94 dosis dan pemberian antibiotik pascabedah sebanyak 1196 dosis. Telah terjadi ketidaktepatan penggunaan antibiotik yang terdiri atas ketidaktepatan indikasi sebesar 0,39%, dosis berlebih dan dosis kurang pada pemberian antibiotik pascabedah berturut-turut sebesar 2,26% dan 0,50%, ketidaktepatan waktu pemberian antibiotik prabedah sebesar 22,34%, interaksi obat sebesar 1,78% yang terdiri atas 0,46% interaksi farmakokinetik dan 1,31% interaksi farmakodinamik, serta duplikasi antibiotik sebesar 0,46%. Dapat disimpulkan bahwa terjadi beberapa ketidaktepatan penggunaan antibiotik. Ketidaktepatan yang paling besar terjadi pada ketidaktepatan waktu pemberian antibiotik prabedah. Dibutuhkan peran serta apoteker rumah sakit sebagai bagian dari upaya peningkatan ketepatan penggunaan antibiotik pada pasien bedah.Kata kunci: Antibiotik, evaluasi penggunaan obat, pembedahan, studi retrospektif Antibiotic Use Evaluation in Surgery Patients at a Private Hospital in BandungAntibiotic administrations in presurgery and postsurgery are widely used to avoid and to treat surgical site infections. In order to ensure the rational use of this drug, the use of antibiotic should be evaluated through drug use evaluation (DUE) programme. In this research, the DUE programme had been carried out based on predetermined criteria using restrospective data study from September until November 2009 to all surgery patients at a private hospital in Bandung. This research showed that 1290 doses antibiotic had been given to patients to treat surgical site infections, which were consist of 94 doses presurgery antibiotic and 1196 doses postsurgery antibiotics. This study showed the presence of inappropriate antibiotic uses that consists of 0.39% inappropriate indications; 2.26% overdoses and 0.50% subtherapy doses; 22.34% inappopriate administration timings of presurgery antibiotic; 1.78% drug interactions which 0.46% are pharmacokinetic drug interactions and 1.31% are pharmacodynamic drug interactions; and 0.46% antibiotic duplications. It can be concluded that there is some inappropriate use of antibiotics. The greatest inappropriateness is inappopriate administration timings of presurgery antibiotic. The role of the hospital pharmacist is needed as part of efforts to increse the appropriateness use of antibiotics in surgical patients.Key words: Antibiotic, drug use evaluation, restrospective study, surgery
Swamedikasi di Kalangan Masyarakat Perkotaan di Kota Yogyakarta Widayati, Aris
Indonesian Journal of Clinical Pharmacy Vol 2, No 4 (2013)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (575.339 KB)

Abstract

Penelitian observasional potong lintang ini bertujuan mengeksplorasi prevalensi dan pola swamedikasi di Kota Yogyakarta. Sejumlah 640 sampel di Kota Yogyakarta dipilih secara klaster acak pada periode Maret–Mei 2010. Data yang diperoleh kemudian dianalisis secara statistik deskriptif. Sebanyak 50% dari responden tersebut berswamedikasi satu kali, 33% dua kali dan 17% lebih dari dua kali. Responden yang membeli obat modern sebanyak 86% dan obat tradisional sebanyak 14%. Obat swamedikasi diperoleh dari apotek (42%), toko/warung kelontong (35%), toko obat (7%), dan kombinasi ketiganya (16%). Sebanyak 99% responden sembuh atau setidaknya berkurang keluhannya setelah berswamedikasi. Jika tidak sembuh setelah berswamedikasi, 45% responden menyatakan akan pergi ke dokter, sementara 20% lainnya ke puskesmas, 5% ke rumah sakit dan 5% kembali melakukan swamedikasi. Sumber informasi tentang obat mereka peroleh dari iklan (32%), dokter (17%), teman (17%), dan dari apotek (5%). Alasan mereka berswamedikasi antara lain pengalaman sembuh menggunakan obat tersebut sebelumnya (24%), berpersepsi bahwa penyakitnya ringan (22%), cepat dan praktis (17%) dan murah (13%). Temuan diatas mengindikasikan peluang dari aspek bisnis apotek sekaligus tantangan peningkatan peran profesi apoteker terutama di apotek dalam membantu masyarakat berswamedikasi secara tepat.Kata kunci: Swamedikasi, masyarakat perkotaanSelf-Medication among Urban Population in YogyakartaThis observational cross-sectional study is aimed at exploring prevalence and patterns of SM in Yogyakarta. A cluster random sampling technique was applied to select 640 adults in Yogyakarta between March and May 2010. From a total of 559 completed questionnaires, 247 (44%) respondents who had self-medicated during two previous weeks were included in subsequent analysis. Among these respondents, 50%had self-me-dicated once, 33% twice and 17% more than two times. Eighty-six percent of respondents had consumedmodern medicines while the rest 14% had used traditional ones. The drug for SM was obtained from pharmacies (42%), groceries (35%), drug stores (7%) and combination of those three sources (16%). Most of the respondents (99%) were recovered from their illnesses or at least experienced a symptom relieve after SMs. Forty-five percent respondents stated that they will visit a physician when they see no improvement after SM, while the rest said they will visit primary healthcenters (20%) and hospitals (5%) orrepeat their SM (5%). Information about the medicines areobtained from advertisements (32%), physicians (17%), friends (17%) and pharmacists (5%). The motivation for SM are previous experience of being relieved (24%), perception that they haveminor illnesses (22%), quick and easy (17%) and cheap (13%). Above findings indicate a business opportunityof pharmacies and a challenge to improve the role of pharmacists in assisting people regarding the selection of medicines for SM.Key words: Self-medication, urban people
Evaluasi Penggunaan Obat Antihipertensi pada Pasien Stroke Iskemik di Rumah Sakit Stroke Nasional Bukittinggi Juwita, Dian A.; Almasdy, Dedy; Hardini, Tika
Indonesian Journal of Clinical Pharmacy Vol 7, No 2 (2018)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.91 KB) | DOI: 10.15416/ijcp.2018.7.2.99

Abstract

Obat antihipertensi menjadi salah satu obat yang paling banyak diresepkan pada pasien stroke iskemik. Penatalaksanaan hipertensi yang tidak tepat pada kedaruratan neurovaskular akut dapat meningkatkan risiko kerusakan otak dan saraf. Penggunaan obat antihipertensi harus dievaluasi melalui program evaluasi penggunaan obat (EPO) untuk menjamin penggunaan obat yang rasional. Penelitian ini bertujuan untuk mengkaji kerasionalan/ketepatan penggunaan obat antihipertensi pada pasien stroke iskemik meliputi tepat indikasi, tepat obat, tepat regimen dosis dan tepat pasien. Penelitian ini merupakan penelitian deskriptif retrospektif dengan menggunakan data rekam medis 150 pasien stroke iskemik. Kriteria inklusi penelitian yaitu semua pasien stroke iskemik nonkardioemboli dan tanpa komplikasi yang menerima terapi antihipertensi di Instalasi Rawat Inap (IRNA) Rumah Sakit Stroke Nasional (RSSN) Bukittinggi pada tahun 2016. Evaluasi ketepatan dilakukan secara deskriptif dengan membandingkan data penelitian terhadap literatur. Hasil penelitian menunjukkan ketepatan penggunaan obat antihipertensi yaitu 100% tepat indikasi; 84% tepat obat; 96% tepat dosis; 98% tepat frekuensi; dan 100% tepat pasien. Jenis ketidaktepatan yang paling sering ditemui adalah ketidaktepatan kombinasi obat serta ketidaksesuaian pemilihan obat dengan stage hipertensi yang diderita pasien. Dibutuhkan peran apoteker rumah sakit sebagai bagian dari upaya peningkatan ketepatan penggunaan obat pada pasien stroke.Kata kunci: Antihipertensi, evaluasi penggunaan obat, stroke iskemik, tepat dosis, tepat indikasi, tepat obat Evaluation of Antihypertensive Drug Use on Ischemic Stroke Patients at National Stroke Hospital BukittinggiAbstractAntihypertensive drugs are the most widely prescribed drug for ischemic stroke patients. Inappropriate management of hypertension in acute neurovascular emergencies may increase the risk of brain and nerve damage. Use of antihypertensive drugs should be evaluated through a drug use evaluation program to ensure rational use of drugs. This study aimed to examine the rationale for the use of antihypertensive drugs in patients with ischemic stroke including indications, drugs, dosage regimens and patients. This research was a retrospective descriptive study using medical record data of 150 ischemic stroke patients who met the inclusion criteria, i.e. all non-cardioembolic and uncomplicated ischemic stroke patients receiving antihypertensive therapy in Inpatient Care (IRNA of National Stroke Hospital Bukittinggi (RSSN) in 2016. The evaluation of accuracy was done descriptively by comparing the research data with the literature. The results showed that 100% of medication use was precisely indicated; 84% precise medication; 96% right dose; 98% exact frequency; and 100% precise patient. Inappropriate drug selection compared to the stage of hypertension and incorrect drug combinations were the most common types of inappropriate medications found in this study inaccuracies. It takes the role of hospital pharmacists as part of efforts to improve the accuracy of drug use in stroke patients.Keywords: Antihypertensive, correct dose, drugs use evaluation, ischemic stroke, precise indication, proper drug
Dampak Self Efficacy terhadap Perilaku Inovasi Apoteker di Rumah Sakit Wahyuningrum, Sri M.; Widianto, Sunu; Abdulah, Rizky
Indonesian Journal of Clinical Pharmacy Vol 1, No 2 (2012)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (614.664 KB)

Abstract

Rumah sakit selalu dituntut agar dapat meningkatkan mutu pelayanan sesuai dengan standar profesi yang sesuai dengan kode etiknya. Oleh karena itu, tenaga kesehatan di rumah sakit, khususnya apoteker, dituntut untuk terus meningkatkan pelayanannya kepada masyarakat. Untuk meningkatkan pelayanan kesehatan kepada masyarakat, maka apoteker harus berinteraksi dan diterima oleh tenaga kesehatan professional lainnya di rumah sakit. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh self efficacy apoteker terhadap organisasinya di rumah sakit yang menjadi dampak terhadap perilaku inovasi. Penelitian ini menggunakan metode kuantitatif yaitu observasi dengan menggunakan kuesioner sebagai alat ukur. Hasil penelitian diukur menggunakan angka berupa nilai, peringkat, dan frekuensi yang dianalisis dengan menggunakan statistik untuk menjawab pertanyaan atau hipotesis penelitian dalam melakukan prediksi bahwa suatu variabel tertentu mempengaruhi variabel yang lain. Prediksi ini dilakukan dengan menggunakan software smart PLS. Hasil penelitian secara statistik menunjukan adanya pengaruh yang signifikan antara self efficacy terhadap perilaku inovasi apoteker di rumah sakit. Seorang apoteker yang memiliki self efficacy yang tinggi akan memiliki perilaku inovasi yang tinggi dalam menjalankan pekerjaan kefarmasiannya di rumah sakit.Kata kunci: Self efficacy, perilaku inovasi, apoteker di rumah sakitImpact of Self Efficacy on Innovative Behaviour Pharmacist in HospitalAbstractHospitals are always required in order to improve the quality of service in accordance with professionalstandards in accordance with their code of ethics. Therefore, health workers in hospitals, especiallypharmacists, are required to continuously improve its service to the community. To improve health servicesto the community, then the pharmacist must interact and be accepted by other professional healthpersonnel in hospitals. The purpose of this study was to determine the effect of self-efficacy pharmacistin a hospital organization that became an impact on innovative behavior. This study used an obsevationalquantitative measurement using questionnaire instrument. The results measured by number consistof value, rank, and frequencies were analyzed using statistics software smartPLS to answer the researchquestion or hypothesis to predict a particular variable affects another variable. The results showed thateffect between self-efficacy of behavioral innovations in the hospital pharmacist significantly different.A pharmacist who has high self-efficacy will obviously have the higher innovation behavior in hospitals.Key words: Self-efficacy, innovative behavior, hospital pharmacist

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