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Medula
Published by Universitas Halu Oleo
ISSN : 23391006     EISSN : 24430218     DOI : http://dx.doi.org/10.33772/medula
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
MEDULA mengundang kontribusi bagi penelitian original dan fundamental pada bidang kesehatan sebagai sebuah artikel yang melewati proses review.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 153 Documents
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ANALISIS FAKTOR RISIKO MEROKOK, STRES DAN RIWAYAT KELUARGA YANG BERHUBUNGAN DENGAN KEJADIAN PENYAKIT JANTUNG KORONER I Putu Sudayasa; Sjarif Subijakto; Wa Ode Asfiyai Sahrul
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 1, No 2 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (397.374 KB) | DOI: 10.46496/medula.v1i2.193

Abstract

Heart disease is the number one cause of death in the world, including Indonesia. According to the World Health Organization (WHO), 60 % of all causes of death of heart disease are coronary heart disease (CHD). Coronary heart disease can attack at reproductive age and cause of sudden cardiac arrest and death. This study aims to determine smoking, stress and family history are risk factors associated with the incidence of coronary heart disease. This research is an observational analytic study with case control design. This research was done at the General Hospital Bahteramas Southeast Sulawesi Province in February-March 2014. Sample in this study consisted of 49 respondents of cases and 49 respondents of controls were taken by purposive sampling with matching on age, sex, blood pressure, dyslipidemia, diabetes mellitus, body mass index and history of alcohol consumption. Data collection using medical records and questionnaires. The statistical test using odds ratio with 95% confidence intervals. The results showed that smoking is a risk factor associated with the incidence of coronary heart disease (OR = 2.450, 95 % CI = 1.050 - 5.713), stress is a risk factor that is associated with the incidence of coronary heart disease (OR = 6.250, 95 % CI = 2.353 -16.598) and family history are risk factors associated with the incidence of coronary heart disease (OR = 9.4, 95 % CI = 2.005 - 44.061). Smoking, stress and family history are risk factor associated with coronary heart disease with opportunities respectively at 2,4 times, 6,2 times and 9,4 times compared with control population.Keywords : Coronary Heart Disease, Smoking, Stress, Family History, Premature CAD
UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL RUMPUT LAUT (Eucheuma sp) PADA BERBAGAI TINGKAT KONSENTRASI TERHADAP PERTUMBUHAN BAKTERI Escherichia coli DAN Staphylococcus aureus Indria Hafizah; Nur Illiyin Akib; Muhammad Fajrianto
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 1, No 2 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.655 KB) | DOI: 10.46496/medula.v1i2.194

Abstract

Red algae seaweed Eucheuma sp containflavonoids compound which has activity as anantibacterial. Thisstudyaimstodeterminethe difference of seaweed methanol extract(Eucheuma sp) on inhibiting the growth ofEscherichia coli andStaphylococcus aureusbacteria. This research was conducted with post–test only design (one-shot case study) with a variable treatment of theseaweed methanolextract (Eucheuma sp) against S. aureus and E. coli.Extractswerethendividedinto 5 concentration of 75%, 50%, 25%, 5%, and non-extraction (squeezed). Analysis of data t odetermine the level of concentration differences seen from the ANOVA test (analysis of variance) followedby a posthoc test. The results of bivariat analysis showed the inhibition of E. coli bacteria there are difference in clear zone diameter which are significant various levels of each concentration, with a value of p = 0.000(p < 0.05) and in S. Aureus inhibition P = 0.073 (p > 0.05) which means there is no difference in the diameter of clear zone at various levels for each concentration. The conclusions of this research are differences extract concentration have effect on the inhibition of the growth of the bacterium Escherichia coli and the difference in concentration of the extract have no effect on the inhibition of growth of Staphylococcus aureus.Key words : Eucheuma sp, Escherechia coli, Staphylococcus aureus
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN LOW BACK PAIN PADA PEKERJA FURNITURE Mario Polo Widjaya; Haeril Aswar; Semuel Pala’langan
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 1, No 2 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.984 KB) | DOI: 10.46496/medula.v1i2.196

Abstract

Low back pain is a sensation of pain in the lumbosacral and sacroiliaka region. The main causes of low back pain is mechanical factors include strain and sprain that occurs in severe and repeated physical activity. The aim of this study was investigated the relationship between stance and position of work, age, smoking habits and overweight with the low back pain incidence among furniture workers in Kambu District Kendari City. This study used cross-sectional study design. There were 100 samples in this study, chosen using cluster sampling. Data collection was derived from direct observation workplace and analyzed using Chi-Square statistical test. The study result show that 43 respondents (43%) were LBP and 57 respondents (57%) were not LBP. The low back pain incidence was found mostly in the stance and position of work (> 45o) (74,4%), age group 36-45 year (37,21%), mild smokers (60,5%) and overweight (51,2%). The bivariate analysis results show that age variable related with low back pain incidences (p=0,004), overweight variable related with low back pain incidences (p=0,011), stance and position of work variable related with low back pain incidences (p=0,00) dan smoking habits variable didn’t related with low back pain incidences (p=0,307). The conclusion of this study that there were a relationship between stance and position of worker, age and overweight with the low back pain incidences, whereas smoking habits were not relating to the low back pain incidences.Keywords : low back pain, stance and position of work, age, smoking, overweight
UJI DAYA HAMBAT EKSTRAK DAUN SIRSAK (Annona muricata L.) DAN DAUN SIRIH (Piper betle L.) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli Eka Suci Fitria; Imran Imran; Sulastrianah Sulastrianah
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 1, No 2 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (577.279 KB) | DOI: 10.46496/medula.v1i2.197

Abstract

Soursop (A. muricata L.) and betel (P. betle L.) are common plants that traditionally used as a medicine. The aims of this study are to determine the Minimum Inhibitory Concentration (MIC) of soursop leaves benefits and betel leaves extract that can inhibit the growth of E. coli one of the cause of diarrhea and the most potentially extract between that plants. Methode of this research used post test control only design and cotrimoxazole (as a control). This study consists of three phases : (1)sample preparation, (2)extraction by maceration with methanol and obtained as much as 14.97 g of leaf extract of A. muricata.L and 2.88 g of P. betle L. after evaporated, (3)MIC using the disc diffusion method. The concentration of each extract are 80,000 ppm, 40,000 ppm, 20,000 ppm, 10,000 ppm, 5000 ppm, 2500 ppm, and 1250 ppm. Ten μL of each extracts was taken and saturated to a paper disc. The results of this study showed that the A. muricata L leaf extract begin to show inhibition at concentration 2500 ppm and P. betle.L is at concentration 5.000 ppm. The conclusion of this study is the MIC of A. muricata L. and P. betle L.leaf extract are 2500 ppm and 5000 ppm sequentially.Key words: A. muricata L., P. betle L., Minimum Inhibitory concentration, E. coli
PENGARUH INTERVENSI PENYULUHAN TERHADAP PENGETAHUAN DAN SIKAP REMAJA TENTANG KESEHATAN REPRODUKSI Waode Sitti Asfiah Udu; Putu Yayuk Widyani Wiradirani
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 1, No 2 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.801 KB) | DOI: 10.46496/medula.v1i2.198

Abstract

Current teenager are very susceptible about risk of healthy damage such as STDS, HIV/AIDS, undesirable pregnancy and abortions. It caused by many factor, one of them is knowledge and attitude of teenagers about reproduction health. The aim of this study is to detect influence of elucidation toward knowledge and attitude of High School students. The method of this study is used pre-experiment design one group pretest-postest. The population is grade XI of high school student and 71 student as a sample. The Data is required by questionnaire and analized by paired t-test. Result of this study show that the rate of score of knowledge and attitude increase after elucidation (p<0,05). The conclusion of this study is elucidation have significantly statistic incease the knowledge and attitude of teenagers about reproduction health.Key words: elucidation, knowledge, attitude, reproduction health
UJI DAYA HAMBAT EKSTRAK DAUN TAPAK KUDA (Ipomoea pes caprae (L) R. Br. ) TERHADAP Staphylococcus aureus Alminsyah Alminsyah; Indria Hafizah; Sulastrianah Sulastrianah
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.999 KB) | DOI: 10.46496/medula.v2i1.240

Abstract

Ipomoea pes caprae (L) R. Br are commonly used by the Indonesian’s people to treat wounds, ulcers and as antioxidant.  Based  on  previous  research  it  was  contains  terpenoids,  saponins, alkaloids,  tannins  and flavonoids. The aim of this study is to determine inhibition capacity of I. pes caprae (L) R. Br leaf extract toward Staphylococcus aureus isolated from patients infected wounds at a concentration of 100 % , 50 % , 25 % , 12.5 %  ,  6.25  %  ,  3.125  %  and  1.56  %. This  research  was  conducted  with  post-test  design  with  a  control  only. Erythromycin is  used as a control. One gram of  extract dissolved  in  10  ml  of  chloroform. Inhibition  zone  is measured  by  paper  disc  diffusion  method  on  Mueller  Hinton agar. Bivariat  analysis  showed  that there  is statistically significant differences of diameters of inhibition zone from each concentration (p=0,00) including control (p=0,00). Conclusion of this study are I. pes caprae (L) R. Br leaf chloroform extract have capacity to inhibit S. aureus growth and the inhibition respond increase with concentration. Keywords : Ipomoea pes caprae (L) R. Br, Inhibition test, Erythromycin, Staphylococcus aureus
POTENSI YANG HILANG BERDASARKAN HEALTH RELATED QUALITY OF LIFE PADA PENDERITA KANKER PAYUDARA DI MAKASSAR SULAWESI SELATAN Muhammad Basir Palu; Andi Armyn Nurdin
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.888 KB) | DOI: 10.46496/medula.v2i1.241

Abstract

Kanker payudara  (KPD)  merupakan  jenis  kanker  yang  paling  sering  ditemukan  pada wanita usia pertengahan. Selain penderitaan fisik dan fungsional, wanita dengan KPD sering mengalami  gangguan atau   penurunan  kualitas  hidup. Penurunan   kualitas  hidup  tersebut dapat dinilai  dengan  menentukan Health  Related  Quality  of  Life  (HRQOL)yang mengutamakan penilain tentang  kesehatan  fisik,  status  psikologi,  hubungan  sosial,  tingkat kemandirian  dan  spiritual. Tujuan penelitian  untuk mengetahui  potensi  yang  hilang berdasarkan Health  Related  Quality  of  Life  (HQROL) pada  penderita  kanker  payudara   di Kota Makassar. Metode penelitian ini merupakan survey analitik secara studi potong lintang (cross  sectional  study) dengan  melakukan  eksplorasi pada  30  kasus  Kanker  Payudara berdasarkan Health Related Quality of Life (HQROL)di Kota Makassar. Hasil penelitian ini menunjukkan sebagian  besar  (66.7%) mengalami  gangguan melakukan  aktivitas  harian, namun  hanya  sebagian  kecil  (33%)  yang  meninggalkan  pekerjaannya. Sebagian  besar (66.7%)  penderita masih  dapat  melakukan  kegiatan  olah  raga  ringan. Kebanyak  responden merasakan  nyeri yakni sebanyak  22  orang  (73.33%) dan  sebanyak 16  orang  (53.33%) meninggalkan  pekerjaan  karena  rasa  nyeri. Responden yang  memiliki  rasa tidak  nyaman sebanyak 18 orang (60%) dan sebagian besar responden meninggalkan pekerjaan disebabkan adanya  rasa  tidak  nyaman  sebanyak  22  orang  (73.33%). Sebanyak   60%  sampai 86.67% mengalami  gangguan  kesehatan  psikologis  berupa  gangguan  stress  emosional  dan meninggalkan  pekerjaan  karena  stress. Tingkat  kemandirian  pasien  KPD  cukup  tinggi, sebagian  besar  responden  yakni  22  orang  (73.33%)  tidak  membutuhkan  orang  lain  untuk merawat  diri  dan  aktivitas  gerak. Sebagian  besar  gangguan  dalam  hubungan  sosial  bagi responden  adalah  gangguan berinteraksi  dengan  masyarakat  sebanyak  18  orang  (60%). Hanya sebagian kecil responden mengalami gangguan spiritual yakni berkisar antara 13.33% -33.33%. Penilaian  berdasarkan EUQOL  yang  berhubungan  dengan mobility,  self  Care, usual activities, pain and discomfort, anxiety and depression. Sebagian besar penderita KPD (60-67%) mengalami beberapa masalah ringan/sedang, hanya sebagian kecil yakni berkisar 0-13%  mengalami  masalah  besar. Kesimpulan penelitian  adalah  sebagian  besar  penderita KPD  mengalami  potensi  yang  hilang  dalam  hal   gangguan  aktivitas  harian,  rasa  nyeri, gangguan   stress  emosional  ringan  dan sedang  (kecemasan  dan  depresi) dan  gangguan berinteraksi dengan masyarakat. Namun penderita KPD masih memiliki kemandirian dalam perawatan diri dan aktivitas gerak, serta adanya peningkatan kesadaran spiritual. Kata kunci: Potensi yang hilang, kualitas hidup (HRQOL)
PERBEDAAN KEJADIAN INFEKSI CACING ANTARA PETUGAS PENGANGKUT SAMPAH YANG MENGGUNAAN ALAT PELINDUNG DIRI DENGAN PETUGAS PENGANGKUT SAMPAH YANG TIDAK MENGGUNAKAN ALAT PELINDUNG DIRI Lezdyana Nur Islami; Sulastrianah Sulastrianah; Wa Ode Sitti Asfiah Udu
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (61.979 KB) | DOI: 10.46496/medula.v2i1.242

Abstract

Soil  Transmitted  Helminth  (STH)  infection  globally  spread  around  the  worlds.  Incidence  of  helminth infection  more  common  in  childrens,  but  adult  with  special  job  like  garbage  workers  have  same  risk  with  that childrens. The aim of this study is to determine differences between usage of personal protective equipment with the helminth  infection  among garbage  workers that  completely  used  personal  protective  equipement  and  that  not completely used . The method of this study is an observational with cross sectional design. Population in this study are garbage workers at Sanitary Service Wakatobi Regency. Sampling method using total sampling with 59 samples. The data about usage of personal protective equipement have done by observation and faecal examination by direct slide. The differences analysed statistically using Chi-Square test. As a result, it is obtained that among the workers that  not completely using  personal  protective  equipment,  there  27  (60%) samples  are infected  and 18  (40%) samples  are  not  infected.  Among  the  workers  that completely using  personal  protective  equipment, there  is  4 (28,6%) samples are infected and 10 (71,4%) samples are not infected (p = 0,04). The conclusion of this study is there was relation between usage of personal protective equipment with helminth infection in garbage workers. Key Words: Helminth infection, garbage workers, personal protective equipment
PREPARASI FENILBUTAZON DALAM PEMBAWA VESIKULAR ETOSOM DENGAN BERBAGAI VARIASI KONSENTRASI FOSFATIDILKOLIN DAN ETANOL Nur Illiyyin Akib; Suryani Suryani; Halimahtussaddiyah R Halimahtussaddiyah R; Niken Prawesti
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (392.986 KB) | DOI: 10.46496/medula.v2i1.243

Abstract

Phenylbutazone is non steroidal anti-inflammatory drug (NSAID) used  in treatment of joint inflammation such  as  rheumathoid  arthritis.  In  order  to  minimize  irritation  effect  on  gastrointestinal  tract,  the  dose  of phenylbutazone is reduced or administered through transdermal pathways. Flux penetration of drugs across the membrane  can  be  improved  by  using  vesicular  type  of  delivery  system  such  as  ethosome.  This  study  aim  to prepare  phenylbutazone in  ethosome  vesicular  system.  Ethosome vesicular  systems  were prepared  with  various concentrations  of  phosphatidylcholine  (2%  and  3%)  and  ethanol  (30%,  35%,  and  40%).  Vesicles  that  are formed  further  characterized  by  shape,  size  and  entrapment  efficiency.  The  shaped  of  ethosome  produced  is large  unilamellar vesicle.  The size of vesicle  varies  between  0.57 to 0.81  µm  with  the smallest size  on Formula C.  The  highest  entrapment  efficiencies  was  also  on  the  Formula  C  by  59.88%  with  2%  concentration  of phosphatidylcholine and 40% of ethanol. Keywords: phenylbutazone, vesicle, ethosomes.
EVALUASI MUTU PELAYANAN DAN HUBUNGAN ANTARA KEPUASAN KONSUMEN DAN PELAKSANAAN PELAYANAN KEFARMASIAN OLEH APOTEKER PENGELOLA APOTEK DI APOTEK-APOTEK KOTA KENDARI Sunandar Ihsan; Putri Rezkya; Nur Illiyyin Akib
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (426.71 KB) | DOI: 10.46496/medula.v2i1.244

Abstract

Pharmaceutical service  quality relate to consumer’s  satisfaction.  Twenty five percent   curage  of patient can be  found  from  good  pharmaceutical  sevice  and  75%  from  drug  usage.  This  study  aimed  to  determine pharmaceutical  service  quality  in  community  pharmacy  of  Kendari  City  and  to  determine  correlation  between  consumer’s  satisfaction  and  implementation  of  pharmaceutical  service  by  pharmacist  manager.  This  study  is  an observational analytic. Data collected from 519 respondents  through questionnaires in June-August 2014 spread across  ten  community  pharmacies  City  of  Kendari  with  sampling  method  used  simple  random  sampling,  and accidental  sampling  for  pharmacist  manager.  Correlation  test  used  to  determine  correlation  between  cons umer satisfaction and implementation of pharmaceutical care by pharmacist manager in pharmacy. The result showed that the percentage rate is 76.70% for consumer satisfaction with moderate category. Fixed percentage of any document procedures  and  dispensing  time  is  60%  with  moderate  category.  Pharmacist  manager  percentage  that  manages quality guarantee is 40% with less category.  Statistic correlation test showed that there is no cerrelation between consumer satisfaction and implementation of pharmaceutical care by pharmacist manager in pharmacy with p value 0,268 (> 0,05). Keywords: quality service, pharmaceutical service, consumer satisfaction

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