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Pengaruh Ekstrak Labu Siam (Sechium edule (Jacq.) Swartz) Terhadap Waktu Koagulasi Pada Mus musculus Nuralifah Nuralifah; Wa Ode Tika Ertia Wahid; Muhammad Ilyas Yusuf
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Chayote (Sechium edule (Jacq.) Swartz) is a type of vegetable that contains most of the calcium, the calcium in the blood which stimulates the release of thromboplastin phospholipid that will catalyze changes that have not been activated prothrombin into thrombin active. The purpose of this study was to prove the existance fromthe effect of squash extracts against coagulation time in mice. This study is experimental, which is divided into 5 treatment consisted of 3 repetitions. Extracts of squash as the test material is made a concentration of 100 mg / kg, 200 mg / kg, and 300 mg / kg. Observations made by looking fibrin threads formed on the fracture capillary tube ± for 2-6 minutes after exiting the first blood. The study was conducted in the laboratory of Pharmacology Bina Husada Kendari. Statistical analysis of the results obtained from the ANOVA showed that extracts of squash has an effective effect with 15.33 seconds at a concentration of 300 mg / kg. Results of ANOVA and LSD test showed extracts of squash has an effect on coagulation time significantly.Keywords: coagulation time, extract of squash, Sechium edule (Jacq.) Swartz

Hubungan Depresi dengan Kemampuan Dalam Aktivitas Dasar Sehari-Hari Pada Lanjut Usia di Panti Sosial Tresna Werdha Minaula Kendari Dimas Aji Pamungkas; Tomy Nurtamin; Junuda Junuda
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 3, No 2 (2016)
Publisher : Halu Oleo University

According to PPDGJ-III depression is a mental disorder that has three major symptoms of depressive affect, loss of interest and easily tired state, and has seven other symptoms such as reduced concentration, reduced confidence, feelng of guilty, pessimistic, suicidal ideas, sleep disturbance and loss of appetite. These problem could be acute or chronic and lead impaired ability of individuals in everyday activities. Activity Daily Living is work activities of daily routine. Activity Daily Living is a staple for self-care activities. These study aims to determine the relationship between depression and activity daily living the elderly in Panti Sosial Tresna Werdha “Minaula” Kendari. These study was an observational analytic study with cross sectional design. The population from elderly in Panti Sosial Tresna Werdha "Minaula" Kendari. Sample in these study consist of 95 respondent. Elderly male cosist of 35 respondents and female 36 respondents. The sampling method is total sampling. The study instrument used questionnaires Beck Depression Inventory (BDI) to assess depression in the elderly. Assessment Activity Daily Living (ADL) using the Barthel Index questionnaire. Data were analyzed by Spearman test. Data was cosidered significant at p value ≤ 0,05. The Results of these study that 71 respondents was mild depression (43.7%), no depression (33.8%) and moderate depression (22.5%). The Respondent who can perform the Activity Daily Living consist of independently (42.3%), mild dependence (38.0%), moderate dependence (9.9%), heavy dependence (7.0%) and total dependence (2.8%). There were a significant relationship between depression on Activity Daily Living (p = 0.000) with negative correlation direction or opposite direction (r = -0.500). The conclusions of these study indicate that there were relationship of depression of activity daily living the elderly in Panti Sosial Tresna Werdha “Minaula” Kendari.Keywords: Activity Daily Living, Depression, Elderly

Analisis Kadar Kolesterol Low Density Lipoproteinsebagai Faktor Risiko Komplikasi pada Pasien Diabetes Melitus Tipe 2 Pranita Aritrina; Asnah Marzuki; Fitriani Mangarengi
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 1 (2016)
Publisher : Halu Oleo University

Dyslipidemia in type 2 diabetes mellitus (T2DM) can be increased the cardiovascular risk and this condition was equivalent with the elevated of LDL-cholesterol. In type 2 diabetes, LDL was small, dense and more aterogenic. This research was an observational study used cross sectional approach. The samples were 50 samples consist of twenty five of T2DM with non-CHD patient (50%) and twenty five of T2DM with CHD patient (50%) with age 45 years old or more. The level of serum LDL was measured by photometry used ABX Pentra 400. The data was analyzed by statistical method. The result study was conducted that normal LDL level was 9 (18%) patients and abnormal LDL level was 16 (32%) in T2DM with non-CHD patient. While in patient with T2DM with CHD had abnormal LDL level overall (50%). The high level of LDL in T2DM was accelerated complication occurrence, mainly coronary heart disease (CHD).Keywords: Type 2 diabetes mellitus (T2DM), dyslipidemia, LDL level, CHD complication

Analisis Faktor-Faktor Risiko Kejadian Katarak di Daerah Pesisir Kendari Alfi Laila; Ilyas Raupong; Juminten Saimin
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACTBackground:Cataract is a condition where lens that usually clear and transparent become cloudy. Based on the last report, cataract is responsible for 51% of blindness that happen in the world, which presented around 20 millions people. In Indonesia, the estimate of incindent rate of cataract is 0.1% a year which means every year there is one person a new patient of cataract among 1000 people. The occurrence of cataract cannot be separated from the risk factors that affect it. Purposes:This research aims to determine the risk factor of the occurrence of cataract in costal area of kendari. Methods:This research is observational analytic research with case-control matching design. The population were all patients who visited the Puskesmas Abeli, Nambo dan Mata in 2015-2016. The sampling method is purposive sampling with the cases are those patient who was diagnosed with cataract and the control are not. The samples are 62 people with the comparison cases and controls is 1:1 so that the number of cases-samples are 31 people and controls-samples are 31 people who had been matched such as age and gender. The instrument of this research is questionnaire. Data were analyzed by determining the odds ratio. Results:The result of this research showed that job, income, and education are a risk factor for the occurrence of cataract which have meaningful statistically. Smoking habit and drink alcohol are a risk factor for the occurrence of cataract which doesn’t have meaningful statistically. The result of bivariat test for job is OR:2.908(CI95%:1.031-8.204), income OR:3.067 (CI95%:1.053-8.934), education OR:3.431 (OR95%:1.100-10.704), smoking OR:1.816 (IC95%: 0.616-5.355) and alcohol OR:2.467 (IC95%:0.733-8.369) Conclusions:The conclusions of this research is that job, income and education is a meaningful risk factor for the occurrence of cataract. Smoking and alcohol is a meaningless risk factor in costal area of Kendari. Keywords: cataract, risk factor

Hubungan Indeks Massa Tubuh dengan Kadar Kolesterol Total pada Staf dan Guru SMA Negeri 1 Kendari Nur Rahma Musadalifa; Satrio Wicaksono; Tien Tien
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACT Background:The nutritional status of adults can be monitored by using the body mass index of nutritional status especially that associated with excess weight and less weight. Overweight can also affect cholesterol levels in the body which is one of the most important factors for determining a person's risk of developing cardiovasculardisease. Research Purposes: The purpose of this research is to know the relationship between body mass index with total cholesterol levels of staff and teachers at SMAN 1 Kendari.Research Methods:This research was an analytic observational study with cross-sectional design. The study population was the entire staff and teachers of SMAN 1 Kendari as many as 103 people. The method used in sampling was total sampling. The number of samples were 51 people. This research was conducted with the approval of spread sheets and questionnaires, measuring height and weight, then measures the total cholesterol level. Data were analyzed using Pearson correlation test. It was considered significant at p value ≤0,05. Research result:The results obtained of this research were the staff and teachers who had a unnormal body mass index as much as 42 respondents (82.3%) and who had normal body mass index by 9 respondents (17.6%). Total cholesterol levels in the staff and teachers gained as much as 20 respondents had normal cholesterol levels (39.2%), as many as 20 respondents had a slightly high cholesterol (39.2%), and as many as 11 respondents had highest cholesterol was (21.6% ). Based on statistical test found that there was a significant relationship between body mass index with total cholesterol (p = 0.001).Conclusion: The Conclusions from this research was there were relationship between body mass index with total cholesterol levels of staff and teachers at SMAN 1 Kendari.Keywords: Body mass index, total cholesterol levels, staff and teachers SMAN 1 Kendari.

Uji Antidiabetik Ekstrak Buah Pare (Momordica charantia L.) terhadap Penurunan Kadar Glukosa Darah pada Mencit yang Diinduksi Streptozotocin Parawansah Parawansah; Nuralifah Nuralifah; Andi Noor Kholidha
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 5, No 1 (2017)
Publisher : Halu Oleo University

ABSTRACT Diabetes mellitus is a chronic disease in which the patient has excess glucose levels in the blood. Pare (Momordica charantia L.) is one of the plants that have efficacy in treating various diseases one of them is antidiabetes. Activity of active substances from the pare may play a role in lowering blood sugar levels. This research is done to know the effect of increasing concentration of pare extract to decrease blood glucose level in mice induced by streptozotocin.This study was experimental laboratory, the study was done by measured the initial blood sugar level in mice, sugar content after induction of steptozotosin, and after administration of 100 mg / kgBW extract test, 250 mg / kgBW and 400 mg / kgBW with observation time for 7 days , as well as gave metformin suspension as a positive control.The results showed that the optimum value of antidiabetic activity of ethanol extract of pare fruit at a concentration of 400 mg / kgBW and had an average decrease of 122 mg / dl.Keywords: Antidiabetes, Momordica charantia L., Streptozotocin

Uji Daya Hambat Ekstrak Etanol Bintang Laut Bertanduk (Protoreaster nodosus) terhadap Bakteri Streptococcus sp. dan Candida albicans Indria Hafizah; Sulastrianah Sulastrianah
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 3, No 1 (2015)
Publisher : Halu Oleo University

Starfish is a marine biota that have potency for used in human health. Protoreaster nodosus is species of starfish that commonly found in water of southeast Sulawesi and not widely used by local community. The aim of this study is to find out bioactive compound and to examine the antibacterial and antifungal bioactivity ethanol exract of Protoreaster nodosus. Thin Layer Chromatography (TLC) is used in bioactive compound assay and disk diffussion method is used to examine antibacterial and antifungal activity. Ethanol extract of Protoreaster nodosus is diluted into 2000 ppm, 4000 ppm, 8000 ppm, 16.000ppm and 32.000 ppm. As the result result of this study, ethanol extract of Protoreaster nodosus are positively containing alkaloid, steroid, saponin, flavonoid and tannin. The diameter of clear zone of disk containing extract in nutrient agar with Streptococcus sp are 4,4 mm, 5,4 mm, 6,7 mm, 9,4 mm dan 11,4 mm, consecutively. The diameter of clear zone of disk containing extract in potato dextrose agar with Candida albicans are 6,6 mm, 9,15 mm, 11,5 mm, 13,95 mm and 20,7 mm, consecutively. In the conclusion, ethanol extract of Protoreaster nodosus from Southeast Sulawesi containing alkaloid, steroid, saponin, flavonoid and tannin. The Antibacterial activity is strong in concentration of 32.000 ppm and the antifungal activity is strong in 32.000 ppm, 16.000 ppm, 8.000 ppm, 4000 ppm concentration. Keywords: Protoreaster nodosus, antibacterial activity, antifungal activity Streptococcus sp, Candida albicans, secondary metabolite

Analisis Penggunaan Insektisida Malation dan Temefos Terhadap Vektor Demam Berdarah Dengue Aedes aegypti di Kota Kendari Sulawesi Tenggara Mubarak Mubarak; Tri Baskoro Tunggul Satoto; Sitti Rahmah Umniyati
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Malathion and temephos insecticides have long been used at Kendari Municipality in the program of Ae.aegypti mosquito as vector of DHF; however, DHF cases are still relatively high. At Kendari Municipality there is no report on susceptibility status of Ae. aegypti larva and mosquito against malathion and temephos insecticides. This study aimed to identify association between frequency and duration of malation and temephos usage with the susceptibility status of Ae. aegypti larva and mosquito at Kendari Municipality and to identify resistance mechanism of Ae. aegypti larva and mosquito. This study was an observational analytic and subjects of the study were Ae. aegypti larva and mosquito collected from five county in Kendari. Susceptibility status of Ae. aegypti larva and mosquito against malathion and temephos was qualitatively assessed through biochemical test and quantitatively assessed through bioassay test. The statistical analysis perform by using Pearson and One Way Anova. as result, biochemical test of Ae. aegypti larva at counties of Kadia, Rahandouna, Kasilampe and Labibia had tolerant status with average score 2.49; 2.15; 2.05; 2.50 and at Abeli had susceptible status with average score 1.77. Biochemical test of test larva from Kadia, Rahandouna, Kasilampe, Labibia and Abeli showed susceptibility status 0%, 3.33%, 23.33%, 0% and 16.67% subsequently. The result of bioassay test of Ae. aegypti larva against temephos at Kasilampe was resistant (73.3%), at Rahandouna was tolerant (89.3%) and Kadia, Labibia and Abeli were susceptible (100%). The result of bioassay test of susceptibility status of Ae. aegypti mosquito against malathion was 100% for all counties. In conclusion, frequency and duration of use of malathion and temephos through biochemical test not affected significantly against downgrading susceptibility status of Ae. aegypti larva; whereas through bioassay test there was significant effect. Increase of non specific esterase enzyme in Ae. aegypti larva using biochemical test was not because temephos and malathion usage but because there were other unknown factors.Keywords: Aedes aegypti, temephos, malathion, bioassay test, biochemical test, insecticides.

Pengaruh Latihan Progressive Muscle Relaxation Terhadap Status Fungsional Dalam Konteks Asuhan Keperawatan Pasien Kanker dengan Kemoterapi di RS Dr.Wahidin Sudirohusodo Makassar Haryati Haryati; Ratna Sitorus
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Chemotherapy is one of the cancer treatment that could provide many side effects and decrease the functional status and quality of life cancer patients. Progressive muscle relaxation (PMR) training is one of the nursing intervention that leads to decreased physical and phsycological effect from chemotherapy. The purpose of this study was to identify the effect of progressive muscle relaxation training on functional status in the context of the nursing care for cancer patients with chemotherapy. This study was a quasi experimental using a nonequivalent control group with pretest and posttest design. The sample was cancer patients who received chemotherapy and inpatient in RS Dr. Wahidin Sudirohusodo Makassar. A concecutive sampling was used as the sample collection method and 48 subjects were obtained this study, divided into two groups, each group consisted of twenty four subjects as intervention group who were given PMR training twice a day for seven days, and twenty four subjects as control group who were not given PMR training. The instrument that used in this study were demography form and Functional Living Index-Cancer to measure functional status which consisted 22 questions with 7-point Likert-Type linear analog scale. A T test was used to examine the differences of the mean of functional status scores and each dimension. The finding showed that there was a significant increased of the mean of functional status after PMR training in intervention group (p=0,000). It means that PMR training has an effect in increasing level of functional status in cancer patients with chemotherapy. It is recommended to apply PMR training as a nursing intervention to cancer patients with chemotherapy and suggested to conduct futher research using more samples.Key Word: cancer, chemotherapy, functional status, progressive muscle relaxation

Analisis Faktor Risiko yang Berhubungan dengan Kejadian Katarak Senilis Di RSU Bahteramas Tahun 2016 Miranty Aditya Hadini; Amiruddin Eso; Satrio Wicaksono
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 3, No 2 (2016)
Publisher : Halu Oleo University

Cataract is a condition where the lens of eyes that normally clear and transparent becomes cloudy. Cataract can cause blindness. Some risk factors related to cataract likes age, sex, diabetes mellitus, UV radiation, smoking and jobs. Some researches argue that these risk factors influence the number of cataracts incidence. This study aims to know the risk factors associated with the incidence of cataracts in Ophtalmology Department in RSU Bahteramas.This study was an analytic observational that used case-control study design. The sample size of this study was 140 respondents consisted of 70 cases and 70 controls were taken by purposive sampling. The data collection was obtained from medical records of patients to determine the age, sex, and history of diabetes mellitus. The instrument of this study was questionnaire to determine their job, education, income and smoking history. Data was declared significant if OR>1.The result of this study has shown that age ≥45 years (OR = 14,397), gender (OR=4.354), history of diabetes mellitus (OR = 10.688), the location of worker (OR = 2.935), education level (OR = 3.842), income (OR = 2.252), and smoking history (OR = 2.771) are risk factors that influence the incidence of senile cataracts.It can be concluded that age, gender, history of diabetes mellitus, outside location worker, low education level, low income, and history of smoking are risk factors for the incidence of senile cataract in RSU Bahteramas Kendari. Keywords :cataract, risk factors, age, gender, history of diabetes mellitus, location of worker, education, income, smoking history.

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Sulastrianah

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sulastrianahmuhtadi@gmail.com

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+6285242541601

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sulastrianahmuhtadi@gmail.com

Editorial Address
Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location
Kota kendari,

Sulawesi tenggara

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Sulastrianah

Contact Email sulastrianahmuhtadi@gmail.com

Phone +6285242541601

Journal Mail Official sulastrianahmuhtadi@gmail.com

Editorial Address Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location Kota kendari, Sulawesi tenggara INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Sulastrianah

Contact Email
sulastrianahmuhtadi@gmail.com

Phone
+6285242541601

Journal Mail Official
sulastrianahmuhtadi@gmail.com

Editorial Address
Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location
Kota kendari,

Sulawesi tenggara

INDONESIA