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Medula

medula
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Published by Universitas Halu Oleo

ISSN : 23391006 EISSN : 24430218 DOI : http://dx.doi.org/10.33772/medula

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

MEDULA mengundang kontribusi bagi penelitian original dan fundamental pada bidang kesehatan sebagai sebuah artikel yang melewati proses review.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 153 Documents

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HUBUNGAN PENGGUNAAN ALAT PELINDUNG DIRI DENGAN KEJADIAN INFEKSI CACING PADA PEKERJA SAMPAH Wa Ode Sitti Asfiah Udu; Sulastrianah Sulastrianah; Lezdyana Nur Islami
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

The prevalence of helminth infection in developing country is higher than other country according World Health Organization (WHO) in 2006. Incidence of helminth infection more common in childrens, but adult withspecial job like garbage workers have same risk with that childrens. The aim of this study is to determine relation between usage of personal protective equipment with the helminth infection in garbage workers. The method of thisstudy is an observational with cross sectional design. Population in this study are garbage workers at Sanitary Service Wakatobi Regency. Sampling method using total sampling with 59 samples. Data collection using questionnaire and faecal examination. and analysed statistically using Chi-Square test. As a result, it is obtained that among the workers that not fully using personal protective equipment, there 27 (60%) samples are infected and 18 (40%) samples are not infected. Among the workers that fully using personal protective equipment, there is 4 (28,6%) samples are infected and 10 (71,4%) samples are not infected (p = 0,04). The conclusion of this study is there was relation between usage of personal protective equipment with helminth infection in garbage workers. Key Words: Helminth infection, garbage workers, personal protective equipment

Analisis Faktor Determinan Proksi Kejadian Hipertensi di Poliklinik Interna BLUD RSU Provinsi Sulawesi Tenggara La Ode Alfariki
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 3, No 1 (2015)
Publisher : Halu Oleo University

Hypertension represent the serious and big problem in all the world. From other side because prevalensi which high enough that is 19,7 % and tend to increase a period of/to to come, also because high ferocity storey;level in the form of permanent handicap and sudden death. Hypertension disease of Regency. hypertension in BLUD General Hospital South East Sulawesi Province that in 2008 the number of new visits to the outpatient hypertension as many as 1672 case, as many as 1758 case in 2009 and in 2010 as many as 1789 case. This study aims to analyze the determinants proxy of occurence hypertension in BLUD general hospitals South East Sulawesi Province. This research have the character of the observasional with the device [of] case study manage the (Case Control Study), where case is hypertension patient, is control the non patient hipertensi.Uji used by Odds Ratio and regresi logistics with the value ά= 0,05. Result of study show there are relation which signifikan to hypertension by family history OR = 6.84 95% CI (3.92 to 11.94), obesity OR = 6.32 95% CI (3.64 to 10.96), consumption of salted fish OR = 9.52 95% CI (5.35 to 16.95), physical activity OR = 8.07 95% CI (4.60 to 14.14), smoking OR = 8.19 95% CI (4.60 to 14.59), stress OR = 5.18 95% CI (3.38 to 9.96), diet OR = 5.44 95% CI (3.12 to 9.50), area of residence OR = 1.53 CI 95% (0.92 to 2.55), on multivariate analysis, consumption of salted fish is a proxy determinant of the incidence of hypertension. Advice need for society to control the risk factors for hypertension by controlling salt consumption, smoking, obesity, regular physical activity, leading a healthy lifestyle, diet.Keywords : hypertension occurence, family history, obesity, consumption of salted fish, physical activity, smoking, stress, diet, area of residence.

Uji Efek Antidiabetik Ekstrak Daun Andong (Cordyline fruticosa L. A. Cheval) Mus musculus yang Diinduksi Streptozotosin Parawansah Parawansah; Sifak Giatna; Muhammad Ilyas Yusuf
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

The plant andong leaf is a medicinal plant that has not been widely used and contains phenolic, flavonoids,tanins and saponins has many benefits, one of which lower blood glucose levels. This study aim to look at the effects of decrease in blood glucose levels in mice that induced by STZs. The method used was experimental research design is RAL with treatment variations leaf extracts 15%, 30% and 45%, glibenclamid as positive control and Na. CMC negative control. The results were analyzed by ANOVA and continued with Duncan. The results showed that there is a very real difference in the treatment given, andong leaf extracts concentrations is themost effective extracts 15% with the average is 17,67 mg/dL on the hour to three.Key words : Leaf andong, antidiabetic, Mus musculus, streptozotocin.

Hubungan Lingkungan Rumah dengan Kejadian Infeksi Saluran Pernapasan Akut (ISPA) pada Masyarakat Pesisir Kelurahan Lapulu Kecamatan Abeli Tahun 2014 Milawati Yusuf; I Putu Sudayasa; Tomy Nurtamin
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 3, No 2 (2016)
Publisher : Halu Oleo University

Acute Respiratory Infection (ARI) is a major cause of morbidity and mortality in children. ARI in Indonesia was ranked 6th in the world, reaching 6 million cases per year. One of factors that influence incidence of ARI is house environment. This study aimed to determine the relationship bertween house environment with acute respiratory infections (ARI) incidence in coastal communities in Lapulu Village, Subdistrict of Abeli 2014. This study is analytical observational with cross sectional study design. The sample size was 88 samples by applying proportional sampling technique. The independent variable were household crowding, natural ventilation, natural lighting, humidity, floor type, wall type and location of the kitchen. The data were analyzed by using chi-square test. The result at significance level α = 0,05 showed that there is relationship between household crowding (p-value = 0,000, CC = 0,415), natural ventilation (p-value=0,000, CC=0,394) , natural lighting (p-value= 0,001, CC= 0,330) , and humidity (p-value=0,015, CC= 0,250) with ARI incidence. Meanwhile, floor type (p-value=0,880, CC= 0,016), wall type (p-value=0,084, CC= 0,181), and location of the kitchen (p-value=0,582, CC= 0,059) does not show a relationship with ARI incidence. The conclusion that there are relationship between household crowding, natural ventilation, natural lighting and humidity with ARI incidence. In contrast, floor type, wall type, and location of the kitchen are not related with ARI incidence. Keywords : Acute Respiratory Infection (ARI), house environment, coastal communities

Uji Aktivitas Ekstrak Etanol Daun Dadap Serep (Erythrina lithosperma Miq) sebagai Antibakteri terhadap Bakteri Salmonella typhi Andi Noor Kholidha; I Putu Wira Putra Suherman; Hartati Hartati
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 1 (2016)
Publisher : Halu Oleo University

Dadap serep (Erythrina lithosperma Miq) is one of the plants that grow in Indonesia. Dadap serep leaves are commonly used as a traditional medicin. It can be used as an antimicrobial. This study aims to determine the inhibition of Dadap Serep (Erythrina lithosperma Miq) Leaf Extract on the growth of the bacteria Salmonella typhi. The methods used in this research was an analytic experimental test. The samples of this study are Leaf Extract of Dadap Serep (Erythrina lithosperma Miq), which is divided into eight concentration, i.e. the concentration of 200,000 ppm, 100,000 ppm, 50,000 ppm, 25,000 ppm, 12,500 ppm, 6,250 ppm, 3,125 ppm, 1,560 ppm and two control i.e. a positive controls and a negative controls. Each test was repeated three times. Antibacterial activity test performed by disc diffusion method, wherein the diameter of each extract was determined and assessed their effectiveness inhibitory zone with chloramphenicol. Minimum Inhibitory Concentration (MIC) was determined by disc diffusion method togeth er with the inhibition test. We then measured at the lowest concentration of extract that they can inhibit the bacteria Salmonella typhiTop of FormBottom of Form. The results showed that the leaves of Dadap Serep (Erythrina lithosperma Miq) has antibacterial activity against growth of bacteria Salmonella typhi. MIC seen from the leaves of Dadap Serep is 50,000 ppm with inhibition zone diameter of 1.3 mm were formed. Diameter of clear zone is highest at a concentration of 200,000 ppm with inhibition zone diameter formed is 4.83 mm. Phytochemical test results on Leaf of Dadap Serep (Erythrina lithosperma Miq) retrieved alkaloids, flavonoids, tannins and saponins are positive.From this research it can be concluded that the extracts from dadap serep leaves (Erythrina lithosperma Miq) has antibacterial activity against growth of bacteria Salmonella typhi.Keywords: Dadap serep leaves (Erythrina lithosperma Miq), Salmonella typhi, Minimum inhibitory concentration (MIC), Antibacterial test

Validitas, Reliabilatas dan Dampak Pembelajaran terhadap Tes Objective Structured Clinical Examintaion (OSCE) Ashaeryanto Ashaeryanto
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 1 (2016)
Publisher : Halu Oleo University

Objective Structured Clinical Examination (OSCE) was developed for the first time by Harden at1975 which was used for evaluating clinical skill ability of OSCE Implementation that could give learning positive and negative impact. Objective: To explain validity, reliability of OSCE and investigate OSCE Test Implementation (Objective Structured Clinical Examintaion) impact to learning, especially in study behavior aspect. Discussion: Van Der Vleuten explains that OSCE is a good and useful method in clinical skill evaluation which is based on 5 criterias namely OSCE test have reliability, validity, educational impact, cost efficiency, acceptability. Reliability can be seen in examiner consistency, case variation, and implementation in prosperous time. OSCE have high content, face, concurernt, and construct validity. OSCE can give positive and negative learning impact.Keywords: OSCE, educational impact, performance assessments,validity

Uji Aktivitas Antibakteri Ekstrak Etanol Bawang Putih (Allium sativum) terhadap Pertumbuhan Bakteri Salmonella typhii dan Shigella dysenteriae Gyidian Upa; Agusalim Ali; Yenti Purnamasari
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACT Diseases of gastrointestinal infections, especially those caused by the bacterium Salmonella typhii and Shigella dysenteriae still a health problem in Indonesia. Garlic (Allium sativum) is a traditional medicine which has antibacterial properties. Garlic contains Allisin, alkaloids, tannins and saponins. The purpose of this study was to determine the antibacterial activity of ethanol extract of the bulbs of garlic (Allium sativum) on the growth of the bacteria Salmonella typhii and Shigella dysenteriae. This study is experimental with post test only control group design. Test of inhibition is determined based on the diameter of clear zone formed. Testing was performed against a pure extract of garlic, the positive control, negative control and solvent control for comparison. Each treatment is performed three times. The results showed that the ethanol extract of garlic (Allium sativum) does not produce a clear zone well against Salmonella typhi and Shigella dysenteriae, it can be concluded that the ethanol extract of garlic (Allium sativum) has no antibacterial activity against Salmonella typhii and Shigella dysenteriae. It is recommended to use another method to extract further research as the development or continuation of this research Keywords: Antibacterial activity, garlic(Allium sativum), Salmonella typhi, Shigella dysenteriae.

Formulasi dan Uji Antijerawat Gel Ekstrak Etanol 70% Buah Belimbing Wuluh (Averrhoa Bilimbi Linn.) terhadap Bakteri Propionibacterium acnes Azis Ikhsanudin; Siti Mardhiyah
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 5, No 1 (2017)
Publisher : Halu Oleo University

ABSTRACT Belimbing wuluh fruit known have flavonoids that has a function as natural anti bacterial for acne treatmeant. To easer in using it, so it formulated in the form of gel. The aims of research was to know the influence of variation concentration ethanol extract 70% belimbing wuluh fruit to physical characteristic of gel and antibacterial activity of Propionibacterium acnes which a bacteria causes acne. Belimbing wuluh fruit extract was obtained by maceration. Extract formulated in the form of gel with variation concentration 4,17%w/v, 8,33% w/v, 12,5%w/v, 16,67%w/v, and 20,83%w/v. Antibacterial activity test was conducted by cup plate technique difusion methode and physical characteristic test covered organoleptic test, spreadibility test, and adhesivity test. The result of antibacterial test and physical characteristic test were analyzed statistically using Kruskall Wallis test and Mann Whitney test with 95% level confidence. The result of research showed that with an increasing concentration of extract could affect physical characteristic of gel and will increase antibacterial activity. The higher concentration extract, the color of gel obtained more concentrated, pH of gel be acid, decreasing adhesive power, spread power obtained smaller and inhibition diameter obtained bigger. The result of research obtained that formula 2 was a good formula with pH value 5, average adhesive power was 4,63 seconds ± 0,57, average spread power was 11,34 cm2 ± 0,44 and average diameter obstruent was 5 mm ±1,41. Based on the research could be concluded that gel extract ethanol 70% belimbing wuluh (Averrhoa bilimbi Linn) fruit had antibacteria activity against Propionibacterium acnes. Minimal concentration which could inhibit growth that bacteria found at concentration 5% and formula which had a good physical characteristic at formula 2.Keywords : Gel, Etanolic extract 70%; Averrhoa Bilimbi Linn, Propionibacterium acnes.

Uji Aktivitas Antibakteri Ekstrak Metanol Rumput Laut (Kappaphycus alvarezii) pada Berbagai Tingkat Konsentrasi terhadap Pertumbuhan Bakteri Streptococcus mutans Agus Saifuddin; Sapto Raharjo; Amiruddin Eso
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 3, No 1 (2015)
Publisher : Halu Oleo University

Red algae Kappaphycus alvarezii contain flavonoids compound which has activity as an anti bacterial. This study aims to determine the difference of inhibition zone of the growth of Streptococcus mutans bacteria by seaweed methanol extract (K. alvarezii) at each concentrations. This research was conducted by post–test only design (one-shot case study) with a variable treatment of the seaweed methanol extract (K. alvarezii) against S. mutans. Extracts were then divided into 7 concentration of 5%, 25%, 50%, 65%, 75%, 85%, and 95%. Data were analyzed to determine the difference of inhibition zone seen from the ANOVA test (analysis of varience) followed by a post hoc test. The results of the bivariate analysis showed there were no difference of inhibition zone of the growth of S. mutans bacteria by seaweed methanol extract of K. alvarezii at the concentration of 65%, 75%, 85%, and 95% (p = 0,143). This research concluded that there were no defference of inhibition zone of the growth of S. mutans bacteria by seaweed methanol extract of K. alvarezii.Keywords : Kappaphycus alvarezii, Streptococcus mutans

Pengaruh Kadar Gula Darah terhadap Kejadian Reinfark dan Kematian pada Penderita Sindroma Koroner Akut Jamaludin Jamaludin; Zaenab Djafar
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 3, No 1 (2015)
Publisher : Halu Oleo University

Recent decades data relates between admission hyperglycemia and mortality that increase among acute coronary syndrome(ACS) patients. Aim of study is to assess relationship between hyperglycemia and Cardiac Event, i.e. death, reinfarction among ACS patients. This is a prospective cohort study, which was held on March to April 2014 among 83 ACS patients in CVCU Wahodin Sudorohusodo Hospital. Patients was grouped into two groups, hyperglycemic ACS group and normoglycemic one. Reinfarction and death events at each group was observed within first 30 days after infarction. In this study, it found death and reinfarction events were higher in hyperglycemic group than in normoglycemic group (22 vs 4, RR = 3.7, p=0.026 for death event, and 14 vs 1, RR =8.7, p=0.03 for reinfarction). Conclusion of this study was hyperglycemia is related to reinfartion and death events among ACS patients.Keywords: Acute Coronary Syndrome, Hyperglycemia, Reinfarction, Death

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Sulastrianah

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sulastrianahmuhtadi@gmail.com

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+6285242541601

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sulastrianahmuhtadi@gmail.com

Editorial Address
Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location
Kota kendari,

Sulawesi tenggara

INDONESIA