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INDONESIA
ODONTO Dental Journal
Published by Universitas Islam Sultan Agung
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 3 Documents
 1 
Search results for , issue "vol 13, no 1 (2026): april 2026" : 3 Documents clear
Effectiveness of Licorice Extract (Glycyrrhiza glabra L.) on Traumatic Ulcer with Parameter Study: Macrophage, Neutrophil, and Lymphocyte Syifa, Liftia Layyinatus; Sari, Rina Kartika; Ismail, Dea Maynur Shalima; Pradisha, Rizqila Diva
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.%p

Abstract

Background: Traumatic oral ulcers are common lesions characterized by epithelial loss, pain, and erythematous halos. Healing occurs through four stages: haemostasis, inflammation, proliferation, and remodelling. Licorice root (Glycyrrhiza glabra L.) is known for its anti-inflammatory and immunomodulatory properties. This study aimed to evaluate the effectiveness of licorice extract at various concentrations on macrophage, neutrophil, and lymphocyte cell counts during traumatic ulcer healing.Methods: A post-test only group design was used with five groups: three treatment groups receiving 5%, 10%, and 15% licorice extract, and two control groups (positive: Aloclair; negative: aquadest), each with six mice. Ulcers were induced using a heated burnisher on the labial mucosa. Treatments were applied twice daily using a nano mouth spray. After euthanasia, labial tissues were fixed, processed, and stained with Hematoxylin-Eosin for histological examination under 400× magnification.Result: Phytochemical analysis revealed high flavonoid (44.669) and saponin (38.802) contents in licorice extract. Statistical tests showed significant differences (p < 0.05) in macrophage, neutrophil, and lymphocyte counts among groups. The 10% extract group showed the highest immune cell response, suggesting optimal anti-inflammatory and immunomodulatory effects at this concentration.Conclusion: Licorice extract effectively promotes the healing of traumatic oral ulcers. Among tested concentrations, the 10% extract provided the best therapeutic effect, accelerating healing and regulating inflammatory cell activity more effectively than other doses or controls.
Definitive Endocrown Restoration in First Molar Right Mandibular After Multiple-Visit Endodontic Treatment: A Case Report Mahardika, Christina; Aini, Rizqika Sufi; Asyafiq, Luthfan; Abdurrohman, Muhamat Muhtar S
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.%p

Abstract

Background: Root canal treatment is a dental procedure aimed at preserving teeth and roots that have been infected by bacteria, with the expectation of restoring the tooth’s normal function and aesthetics. The selection of an appropriate final restoration plays a significant role in supporting the success of root canal therapy.Method: A 22-year-old male patient presented to the conservative dentistry clinic with a chief complaint of a cavity in the lower right molar that had been present for the past two years. The patient reported experiencing pain one year ago when the tooth was used for chewing or exposed to sweet and cold stimuli, accompanied by swelling, but no treatment was sought at that time. Currently, the patient no longer experiences pain but feels discomfort due to food impaction in the cavity. The ICD-10 diagnosis for tooth 46 was necrosis of the pulp.Result: The patient reported comfort during mastication and expressed satisfaction with the final restoration. These findings indicate the clinical success of the endocrown restoration, achieving optimal retention, occlusal function, and esthetic outcome.Conclusion: Endocrowns preserve more remaining tooth structure and provide good marginal adaptation. One week after placement, the evaluation showed satisfactory marginal adaptation with no post-treatment complaints. Therefore, endocrowns can be considered a conservative, functional, and esthetic restorative option for endodontically treated posterior teeth.     
Pharmacotherapy And Behavioural-Modifying-Lifestyle For Oral Lesions Management In Multimorbid Patient Post-Pyelolithotomy: A Case Report Pramitha, Selviana Rizky; Izzati, Arissa; Apriasari, Maharani Laillyza; Carabelly, Amy Nindia; Puspitasari, Dewi
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.%p

Abstract

Background: Chronic kidney disease (CKD), a recognized complication of pyelolithotomy along with multimorbidity in the elderly population, presents a higher incidence of oral lesions. Further damage to the renal vasculature interchangeably affects oral-systemic conditions. We report oral lesions management in MCC patient post-pyelolithotomy for better outcomes.  Case: A 65-year-old male patient complained of painful ulceration on the atrophic tongue for two weeks with a fair oral hygiene score. The condition had been managed with various topical agents alternately with no improvement. There was a history of pyelolithotomy and emergency room admission. Laboratory examination presented diabetes mellitus, stage 3B kidney disease and anemia of chronic disease. A diagnosis of ulcerative-type uremic stomatitis with atrophic glossitis in multimorbid patient was obtained. Pharmacotherapy of oral lesion including aloe vera extract mouthwash and povidone-iodine mouthwash showed improvement on the following day. Behavioural-modifying lifestyle involved physical activity, healthy eating, and adherence to treatment (oral hygiene maintenance and regular dental appointment). Systemic conditions were managed by multidiscipline treatment with Internal Medicine. Conclusion: Pharmacotherapy and behavioral modifying lifestyle may support a better prognosis for oral manifestation in multimorbid patient post pyelolithotomy

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