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Pudyastuti Kusumaningrum
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INDONESIA
Majalah Obat Tradisional
Published by Universitas Gadjah Mada
ISSN : 14105918     EISSN : 24069086     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
raditional Medicine Journal (Majalah Obat Tradisional), or Trad. Med. J. (ISSN 1410-5918 (print) and ISSN 2406-9086 (online)), is an international scientific journal published by Faculty of Pharmacy, Universitas Gadjah Mada, three times annually. Collaborating with Indonesian Pharmacist Association, Daerah Istimewa Yogyakarta, and we dedicate our journal to researches and development in traditional medicine. The journal receives papers on research laboratory, field research, and case studies of traditional medicine and its constituent, covering research topics including raw materials, cultivation, phytochemical, pharmacological effects and toxicology, formulation, and biotechnology.
Arjuna Subject : -
Articles 552 Documents
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Exploring the Potential of NIR Spectroscopy and Chemometrics to Verify the Flavonoid Content in Litsea cubeba Cendekiawan, Khrisna Agung; Susanti, Dhina Ayu; Isnawati, Nafisah; Mayasari, Shinta; Riswanto, Florentinus Dika Octa
Majalah Obat Tradisional Vol 30, No 2 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.99185

Abstract

The ancient records about herbal medicine show traditional healing practices are deeply rooted in Indonesian culture. The medical use of plants decreased because of inheritance customs combined with the lack of written documentation on medicinal plants but dependent on oral information transmission. Traditional research and preservation activities of local healing plants which belong to specific cultural communities become possible through this phenomenon. Researchers conducted ethnopharmacological research about antidiarrheal medicinal plant uses that included traditional knowledge about flavonoid-containing plants within the Osing ethnic group of West Java Indonesia. The goal of this research was to verify flavonoid compounds in Osing's medicinal plants through Near Infra-Red (NIR) spectroscopy combined with chemometric methods. The evaluation of antidiarrheal potential for these compounds relied on flavonoid standard reference substances because these compounds demonstrate strong antioxidant properties which stabilize intestinal functioning. Chemometric techniques together with Near Infra-Red spectroscopy (NIR) were applied to analyze krangean leaves (Litsea cubeba) in order to establish their flavonoid compound levels. The quality assessment of multivariate calibration models shows that PLS regression produces RMSEC of 2.870 and RMSEP of 0.0124 with R2cal = 0.9931 and R2val = 0.9919. The analysis using linear discriminant analysis (LDA) succeeded in its completion with recognition rates above 90% for each discriminating class.
Potential of Moringa oleifera (M. oleifera) Leaf Extract as an Antiseptic against Candida albicans using Percentage Kill Test Tjampakasari, Conny Riana; Kiranasari, Aryani; Baswara, R. Muh. Kevin
Majalah Obat Tradisional Vol 30, No 2 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.100119

Abstract

Candida albicans is a commensal microorganism that is commonly found as a normal flora in the body. However, impaired immune conditions can cause this fungus to turn into a pathogen. This Microorganism is one of the causes of mortality and morbidity in the world. The use of antiseptics is beneficial for the prevention and treatment of fungal infections. Moringa oleifera is a plant that is often found in Asia and Africa, has various bioactive components that have the potential to be antiseptic. Until now, there has been no research on the antiseptic potential of M. oleifera against C. albicans. Therefore the study was conducted to test the activity of Moringa leaf extract (Moringa oleifera) as an antiseptic against C. albicans. This experiment was conducted using the percentage kill method to determine the potential activity of the extract as an antiseptic against C. albicans The comparison of bacterial colony growth on the control and the treatment that grew on solid media was calculated according to the set contact time of 1, 2, and 5 minutes. The effectiveness of antiseptics is assessed by calculating according to the percentage kill principle. The results of the calculation of C. albicans colonies in contact time for 1, 2, and 5 minutes were 62.39%, 80.85%, and 90%, respectively. This finding shows that the contact time of 5 minutes has good effectiveness. Therefore M. oleifera leaves have the potential to be an effective antiseptic against C. albicans.

Page 56 of 56 | Total Record : 552

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