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Majalah Obstetri dan Ginekologi

MOG
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Published by Universitas Airlangga

ISSN : 08540381 EISSN : 25981013 DOI : 10.20473/mog.V27I32019.90-93

Core Subject : Health,

Health Professions Medicine & Pharmacology

Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.

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Articles 298 Documents

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Why Mozart compositions during pregnancy should be exposed in the night. Study on apoptotic index of Rattus norvegicus offsprings’ brain neurons Eka Nasrur Maulana; Hermanto Tri Joewono; Widjiati Widjiati; Windhu Purnomo
Majalah Obstetri dan Ginekologi Vol. 25 No. 3 (2017): December
Publisher : Universitas Airlangga

Objectives: To analyze the optimal time to expose Mozart compositions(in the night/ dark) by measuring brain neural apoptotic index of Rattus norvegicus offspringsMaterials and Methods: This study used experimental random-ized post test only control group design in pregnant Rattus norvegicus. Subjects were divided into three groups at random, ie control group, 1 (1 hour Mozart exposure in dark) and 2 (1 hour Mozart in light), each comprised 8 females. After delivery, 2 heaviest Rattus norvegicus offsprings were chosen, totally 15 neonates in each group, then they were sacrificed with decapita-tion and the brain was prepared and stained using TUNEL assay method and the index of neurons cell apoptosis was calculated using microscope in 1000x magnification. This study was conducted at the Faculty of Veterinary Medicine, University of Airlangga, after conducting ethical feasibility test.Results: There were no miscarriages, congenital malformation, preterm birth and deaths in all groups. The control group's neural apoptosis index was 55.98 ± 4.12, group one 24.87±3.45 and group two 23.82±3.89. Based on statistical test result, there was no significant difference of apoptosis index between treatment group 1 and treatment group 2, with p value 0,836 but significant difference was found between control group and treatment group 1 (p=0.002) and between control group and treatment group 2 (p=0.009). In dark group we found the lower average of apoptotic index, the lowest apoptotic index, 9 of 15 had the lowest, the heaviest head weight and 4 of 15 subjects had the heaviest head weightConclusion: There was no significant difference between the pro-vision of Mozart music in dark and light on brain neuron of Rattus norvegicus offsprings although lower average in the dark group especially if the extreme value exluded. In the dark group: we found the lower average of apoptotic index, the lowest apoptotic index, biggest proportion of the lowest index, the heaviest head and biggest proportion of heaviest head.

Correlation between Pelvic Organ Prolapse Symptoms and Age of Menopause Rizqy Rahmatyah; Gatut Hardiyanto; Dwi Susanti
Majalah Obstetri dan Ginekologi Vol. 25 No. 1 (2017): April
Publisher : Universitas Airlangga

Objectives: This study aims to determine the characteristics of patients with POP symptoms in Geriatrics Outpatient Clinic Dr. Soetomo General Hospital.Materials and Methods: This is an analytic observational research with cross-sectional and purposive sampling techniques. The population in this study were patient in Geriatrics Outpatient Clinic Dr. Soetomo General Hospital. Questionnaire was used to collect data and SPSS 21.0 was used for the analysis. 56 patients became subjects in this study. Data were analyzed by chi-square test, Mann-Whitney and Spearman's rho using SPSS 21.0. Results: Data obtained was 13 respondents (23.2%) had symptoms of POP based POPDI-6, with the highest scores of 45.8 (cut-off 75). A significant association was found in the association of menopausal age with symptoms of incomplete voiding (p = 0.036). It is also a risk factor for symptoms of vaginal bulge in patients at Geriatrics Outpatient Clinic Dr. Soetomo General Hospital.

M1 M2 macrophage expression in menstrual blood flakes of women with endometriosis Yulisa Haslinda; Ashon Sa’adi; Hendy Hendarto; Faroek Hoesin
Majalah Obstetri dan Ginekologi Vol. 24 No. 2 (2016): May - August
Publisher : Universitas Airlangga

Objectives: to measure and prove the increase of panmacrophage, macrophages M1 and M2 expression and decrease of ratio of M1/M2 in menstrual blood flakes of women with endometriosis. Materials and Methods: This study was a cross sectional observational analytic study conducted on 30 subjects with endometriosis and non-endometriosis. Immunohistochemical staining was done on a sample of menstrual blood flakes of subjects study who were taken at the second or third day of menstrual cycles with CD68 and CD163 antibody to measure the expression of panmacrophage and M2 macrophages. Expression of M1 macrophages is the approach of a reduction expression of panmacrophage with M2 macrophages.Results: Expression of M1, M2 and the ratio M1/M2 in the both of groups had a normal distribution then continued by independent t-test with one-tailed α (0.05). Probability was considered statistically significant at p <0.05 with a confidence interval of 95%. Based on the statistical result, Mφ macrophage expression in endometriosis and control group amounted to 3.62 ± 0.50 and 2.80 ± 0.64 (p =0.0005) with non parametric test. The expression of M1 macrophages in endometriosis group and non endometriosis were respectively 1.40 ± 0.35 and 1.33 ± 0.40 (p =0.3005) and the expression of M2 in both of group, respectively of 2.23 ± 0.41 and 1.47 ± 0.36 (p =0.0005). The ratio of M1/M2, the endometriosis group and non endometriosis, respectively of 0.65 ± 0.20 and 0.92 ± 0.24 (p =0.0015).Conclusion: this study were significant increased in the panmacrophage Mφ, M2 macrophages expression on a woman's menstrual blood flakes endometriosis and significant decreased in ratio M1/M2 in the woman's menstrual blood flakes endometriosis.

Depression level and quality of life in ovarian cancer patients in Zainoel Abidin Hospital, Banda Aceh Ghina Akmalia; M Riswan; M Andalas
Majalah Obstetri dan Ginekologi Vol. 25 No. 1 (2017): April
Publisher : Universitas Airlangga

Objectives: to determine the relationship between depression and quality of life in ovarian cancer patients who are undergoing chemotherapy in RSUDZA Banda Aceh.Materials and Methods: This study was an analytical observa-tional study with cross-sectional design approach. The samples were taken by using accidental sampling with total of respondents are 30 patients. Depression level was assessed by using the BDI-II questionnaire and quality of life was assessed by using the EORTC QLQ-C30 questionnaire. Then, data were analyzed by using Spearman’s Correlation test.Results: The most of the cases were no depression (53,3%), and good quality of life (56,7%). The lowest cases were patients with severe depression (6,7%), and poor quality of life (16,7%). The results of data analysis obtained p value=0.000 (p≤0,05). Conclusion: there is a significant relationship between depression and quality of life in ovarian cancer patients who are undergoing chemotherapy in RSUDZA Banda Aceh.

Maternal parity and exclusive breastfeeding history are significantly associated with stunting in children aged 12-59 months Syuhrotut Taufiqoh; Purnomo Suryantoro; Herlin Fitriana Kurniawati
Majalah Obstetri dan Ginekologi Vol. 25 No. 2 (2017): August
Publisher : Universitas Airlangga

Objectives: To determine the relationship between maternal parity and exclusive breastfeeding history with stunting among children aged 12-59 months.Materials and Methods: Observational method with case control approach. Sampling method used purposive sampling was conducted in 118 children. Data were collected by observation and interview using questionnaire. Chi square test used to bivariate analysis and logistic regression used to multivariate analysis with 5% significance limit and 95% confidence level.Results: Multivariate analysis results that maternal parity and exclusive breastfeeding history was significantly associated with stunting (OR 3,419 (CI 95%: 1.433-8.156); OR 3,706 (CI 95%:1.430-9.605). External variable significantly associated with stunting is maternal occupation OR 2,972 (CI 95%: 1.285-6.874).Conclusion: Maternal parity and exclusive breastfeeding history are significantly associated with stunting in children aged 12-59 months.

Characteristics overview of mother with perinatal death at Dr. Soetomo Hospital in 2015 Yulisa Haslinda; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 24 No. 3 (2016): September - December
Publisher : Universitas Airlangga

Objectives: to determine the frequency distribution of perinatal mortality and maternal characteristic features in terms of age, parity, gestational age and pregnancy complications in Dr.Soetomo Hospital Surabaya in 2015. Materials and Methods: A descriptive study conducted by collecting data on patients who experienced perinatal mortality of infants born from January to December 2015 in Dr. Soetomo, Hospital Surabaya. Samples were collected using total sampling. The samples must meet the following criteria: mothers of infants with perinatal mortality in Dr. Soetomo Hospital, Surabaya, from January to December 2015.Results: There were 206 perinatal deaths out of 1018 births in Dr. Soetomo during 2015, of which 58% was live birth and 42% was stillbirth. Most of perinatal mortality found in the preterm gestational age as much as 78%, and gestational age 28-<37 weeks (58%). Most of perinatal mortality occured in infants with less than 1500 grams birth weight, which was as much as 53% of all perinatal deaths and infant whose birth weight from1500 to 2500 grams was about 29%. Most perinatal mortality found in multigravida (54%) and in infants whose mothers experienced preeclampsia in pregnancy complications (35%), followed by infant mortality in women with non-obstetric complications (23%).Conclusion: Perinatal mortality in Dr. Soetomo Hospital was mostly found in multigravida mothers, 16-35 years old maternal age, 28-37 weeks gestational age and those with complications of preeclampsia.

The difference of PGE2 and COX-2 expressions in various histological grading of endometrial endometrioid carcinoma Yusfita Evi Rosdiana; Willy Sandhika
Majalah Obstetri dan Ginekologi Vol. 25 No. 1 (2017): April
Publisher : Universitas Airlangga

Objectives: to analyze the expression of PGE2 and COX-2 in various histological grade of endometrial endometrioid carcinoma.Materials and Methods: Analytical observational study was performed on parafin block archives of endometrial endometrioid carcinoma with histological grade 1,2 and 3 in Anatomic Pathology laboratory Dr. Soetomo hospital. PGE2 and COX-2 expression were examined by immunohistochemical staining using PGE2 and COX-2 antibodies. The results were analyzed statistically.Results: There were increase of PGE2 expressions of in endometrioid carcinoma grade 2 compare to grade 1 and grade 3 compare to grade 2. The COX-2 expression was increase in histologic grade 3 compare to grade 1.Conclusion: The expression of PGE2 and COX-2 in endometrial endometrioid carcinoma were increased in higher histologic grade compare to lower histologic grade.

Diagnosis and management of vaginal dryness in menopause Ali Baziad
Majalah Obstetri dan Ginekologi Vol. 24 No. 2 (2016): May - August
Publisher : Universitas Airlangga

Objective: To review the diagnosis and management of vaginal dryness in menopausal womenMethods: Literature reviewResults: Lack of estrogen negatively impacts the vagina and the urinary tract. The vagina becomes dry (atrophic) and then causing pain during sexual intercourse. Vaginal atrophy can be diagnosed in the form of vaginal dryness (75%), painful sexual intercourse (38%), itching and discharge complaints. Sometimes the patient complained pain in urinating, frequent night urination, in-continence and recurrent urinary tract infections. Mucose of the cervix, vagina and vulva are thin. Vagina can bleed easi-ly. Diagnosis can also be made by measuring the pH of the vagina by using litmus paper and vaginal cytology. The management involves administration of local estrogen treatment using weak estrogen (E3) in the form of a cream. E3 cream does not need to be combined with progestogen. Other type of local hormonal therapy (TH) is DHEA cream. Giving a strong estrogen (E2) or equin estrogen should always be combined with progestogen to prevent endometrium hyperplasia, either administered locally or systemically. E3 cream is also safe in women with breast cancer who experienced vaginal atrophy.Conclusion: Lack of estrogen causes vaginal atrophy with symptoms of vaginal dryness. Vaginal atrophy also causes urinary problems. Diagnosis is based on symptoms, examination of vaginal pH and vaginal cytology. The management is by adminis-tering HT with estrogen. E3 creams is the most effective in relieving complaints caused by vaginal dryness and complaints caused by the bladder.

Screening, counseling and referral pattern of structural heart disease in pregnancy cases at public health center in Surabaya Noorma Rina Hanifah; Andrianto Andrianto; Bambang Trijanto
Majalah Obstetri dan Ginekologi Vol. 25 No. 3 (2017): December
Publisher : Universitas Airlangga

Objectives: To depict the process of screening, counseling and re-ferral patterns of structural heart disease in pregnancy cases by public health centre in Surabaya as preliminary data required for the groundwork of standard of care of pregnancy with heart di-sease.Materials and Methods: This is a qualitative research with in-depth interview to PJ KIA doctors selected by purposive sam-pling, the information is confirmed by the Head of Primary Service Management Unit of BPJS Surabaya branch, Family Health Unit staff of Surabaya Municipality Health Office and 8 patients with structural heart disease in pregnancy treated in RSUD Dr. SoetomoResults: The process of early pregnancy screening at the PHC is performed by midwives and GPs in accordance to the format provided by of the Surabaya Municipality Health Office which was not designed for structural heart disease screening in preg-nancy, history taking and special physical examination for scree-ning of heart disease only done if suspicion occurs. Medical and Child Health program overseer doctors have not agreed on which referral facility for pregnancy cases with suspicion of structural heart disease should be directed because there is no guiding regulation. Counseling of pregnant patients suspected of having structural heart disease is still limited to providing infor-mation that PHC are unable to make a diagnosis.Conclusion: The process of screening for structural heart disease during pregnancy has not been done routinely through anamnesis and physical examination. There is no standard guidance on the process of referral of pregnancy cases with suspicion of structural heart disease that can be performed by Mother and Child Health programs overseer doctors. Visits of women with structural heart disease to the PHC to obtain referral letter to secondary / tertiary health facilities and School Health Program programs have not been utilized for counseling on the effect of heart disease on reproductive health.

Profile of patients with post partum hemorrhage in Dr. Soetomo Hospital, Surabaya, January 2011 - December 2013 Mazaya Azyati; M. Aldika Akbar; Sudarno Sudarno
Majalah Obstetri dan Ginekologi Vol. 24 No. 2 (2016): May - August
Publisher : Universitas Airlangga

Objectives: To recognize profile of patients with post partum haemorrhage in Dr. Soetomo Hospital, Surabaya, from January 2011 to December 2013.Materials and Methods: This was a descriptive study using secondary data from medical records of patients with postpartum hemorrhage at Dr. Soetomo Hospital in January 2011 - December 2013. Age, parity, origin, amount of hemoglobin, cause of postpartum hemorrhage, mode of delivery, and transfusion data patients were all recorded.Results: Result of this study were patient’s age, parity, origin, hemoglobin, cause of postpartum haemorrhage, mode of delivery, and transfusion data. From 202 cases, 131 patients (64.85%) were 20 – 35 years old, 134 patients (66.34%) were multipara, 84 patients (41.58%) were from private practice midwife, 70 patients’ (34.65%) hemoglobin were <8 gr%, 63 patients (31.19%) post partum haemorrhage caused by retained placenta, 164 patients (81.20%) labored with spontaneous way, and 131 patients (64.85%) did not receive transfusion.Conclusions: Most of the patients with postpartum hemorrhage were 20-35 years, multiparas, from private practice midwives, came with haemoglobin level <8 gr%, caused by retained placenta, delivered with spontaneous way, and did not receive transfusion.

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