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Majalah Obstetri dan Ginekologi

MOG
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Published by Universitas Airlangga

ISSN : 08540381 EISSN : 25981013 DOI : 10.20473/mog.V27I32019.90-93

Core Subject : Health,

Health Professions Medicine & Pharmacology

Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.

Arjuna Subject : -

Articles 298 Documents

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Dominant factors affecting uterine prolapse in Dr. Moewardi Hospital, Surakarta, in 2013-2015 Asih Anggraeni; Vitri Wulansari; Darto Darto
Majalah Obstetri dan Ginekologi Vol. 25 No. 3 (2017): December
Publisher : Universitas Airlangga

Objectives: To determine the dominant factors that affected uterine prolapse at Dr. Moewardi General Hospital Surakarta.Materials and Methods: This study was conducted to 259 cases of uterine prolapse at Dr. Moewardi Hospital, Surakarta, in the periods of January - December in the years 2013-2015. This was a correlational quantitative analytic study using chi-square test and regression analysis.Results: Factors affecting uterine prolapse were parity (p=0.024), age (p=0.036) and occupation (p=0.039). Parity had the highest regression analysis result of 0.145 with probability of uterine prolapse in those with parity >2 in this study was 2.753 times higher than in those with parity ≤2.Conclusion: Factors that had been proved to have significant effect on uterine prolapse were age, occupation, and parity. Parity was the predominant factor in affecting uterine prolapse in Dr. Moewardi Hospital, Surakarta.

Risk factor of severe preeclampsia in Dr. Soetomo Hospital Surabaya in 2015 Amelia Rahmah Kartika; Muhammad Ilham Aldika Akbar; Pirlina Umiastuti
Majalah Obstetri dan Ginekologi Vol. 25 No. 1 (2017): April
Publisher : Universitas Airlangga

Objectives: to determine which of the risk factors above associated with the occurrence of severe preeclampsia at dr. Soetomo Hospital, Surabaya during 2015.Materials and Methods: The type and design of the study were analytic and retrospective. This study was held in the dr. Soetomo Hospital from April until November 2016. The instrument of the study was the medical records then being coded and analysed. The samples were 134 pregnant women, consisting of 67 pregnant women with severe preeclampsia as cases and 67 pregnant women as controls.Results: Maternal obesity (OR= 5,786; 95% CI: 2,300–14,555), history of hypertension (OR= 6,693; 95% CI: 1,848–24,237) and secondary elderly primi (OR= 6,384; 95% CI: 1,357–30,031) are associated with the development of severe preeclampsia.Conclusion: In conclusion, the significant risk factors of severe preeclampsia in dr. Soetomo Hospital Surabaya during 2015 are obesity, history of hypertension and secondary elderly primi variables.

The use of Maternal and Child Health (MCH) handbook improves healthy behavior of pregnant women Nur Hidayatul Ainiyah; M Hakimi; Anjarwati Anjarwati
Majalah Obstetri dan Ginekologi Vol. 25 No. 2 (2017): August
Publisher : Universitas Airlangga

Objectives: To investigate correlation between maternal and child health (MCH) handbook utilization and healthy behavior of trimester III pregnant women.Materials and Methods: This study used Spearman-Rho non-parametric correlation test with 95% of the Power of Test.Results: The correlation between MCH utilization and the healthy behavior of trimester III pregnant women showed correlation coefficient (r) of 0.530 and CI 95% 0.163-0.638, indicating middle level of correlation with p-value of 0.01 (p<0.05), showing statistical significance.Conclusion: MCH (maternal and child health) handbook utilization improves healthy behavior of trimester III pregnant women. The higher the utilization of MCH, the healthier the behavior of trimester III pregnant women.

Influence of prenatal class to the practice of P4K (Birth Planning and Prevention of Birth Complication) Robitha Faiza; Hari Basuki Notobroto; Bambang Trijanto; Oedojo Soedirham; Ah. Yusuf; Kusuma Halim
Majalah Obstetri dan Ginekologi Vol. 24 No. 3 (2016): September - December
Publisher : Universitas Airlangga

Objective: This study aimed to analyze the influence of prenatal class to the practice of P4K (Birth Planning And Prevention Of Birth Complication).Materials and Methods: This study applied analytical survey with cross sectional approach. The number of samples taken was as many as 30 mothers, using simple random sampling. Analysis of data was carried out using ordinal wilcoxon sign rank test. Datas were obtained from interviews and questionnaire.Result: The influence of prenatal class to practice of P4K (Birth Planning and Prevention of Birth Complication) (p = 0,0000). Conclusion: Prental class can influence to practic of P4K.

Sambiloto (AS201-01) is better than standard antimalarial drug (DHP) in reducing Toll-Like Receptor 2 (TLR2) on placenta malaria model Masyitah Hamidah; Aty Widyawaruyanti; Widjiati Widjiati; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 26 No. 2 (2018): August
Publisher : Universitas Airlangga

Objectives: To compare the TLR2 expression in the placenta between treated by sambiloto EA-96 fraction tablet (AS201-01) and dihydroartemisinin-piperaquine phosphate (DHP)Materials and Methods: Experimental study using 24 pregnant mice. All sample divided into 4 groups with randomization are uninfected group, Plasmodium infected group and given placebo, sambiloto (AS201-01) and DHP. Then performed surgery and placental sampling were staining with adopting in tunnel assay method to measure the TLR2 expression of placental.Results: The expression of TLR2 in uninfected group has the lowest rate compared to other groups. The infected and placebo treated group has the highest TLR2 expression campared with sambiloto and DHP. The sambiloto group has not differ signi-ficantly with the group uninfected and lower than DHP.Conclusion: Tablet of sambiloto EA-96 fraction (AS201-01) decreased TLR2 expession better than with DHP tablet.

Knowledge of pregnant women about anemia is related with adherence to iron tablets Baksono Winardi; Elga Caecaria Grahardika Andani
Majalah Obstetri dan Ginekologi Vol. 26 No. 1 (2018): April
Publisher : Universitas Airlangga

Objectives: to identify association between knowledge of pregnant women about anemia and the adherence to consume iron tablets in BPM Titik Suharti, Surabaya, IndonesiaMaterials and Methods: Observational analysis cross sectional study. Population consisted of 55 trimester pregnant women in BPM Titik Suharti, Surabaya, in March-April 2017. Samples were recruited using consecutive sampling. The number of sample was 35 respondents. Data were analyzed using chi-square test.Results: This research showed that all of the less knowledgeable women on anemia (100.00%) were non-adherent to consume iron tablets, almost all moderately knowledgeable women (92.9%) were adherent, and all of the fully knowledgeable women (100.00%) were adherent. Fisher exact test in significance level of 0.05 revealed p value equal to 0.0001, indicating association between knowledge about anemia and adherence to consume iron tablets at BPM Titik Suharti, Surabaya, Indonesia.Conclusion: There is an association between knowledge of pregnant women about anemia with adherence to iron tablets.

Nitric oxide (NO) level of the follicular fluid in endometriosis patients Cahyono Hadi; Djaswadi Dasuki; Ahmad Hamim Sadewa; Indwiani Astuti; Awal Prasetyo
Majalah Obstetri dan Ginekologi Vol. 26 No. 1 (2018): April
Publisher : Universitas Airlangga

Objectives: To ascertain the nitric oxide (NO) level of the follicular fluid of endometriosis sufferers compared with that of the non-endometriosis patients.Materials and Methods: Follicular fluid was taken from 64 women, but only 54 continued with further laboratory test. Women with endometriosis had their follicular fluid taken during laparoscopy, while the follicular fluid from non-endometriosis women was taken during tubectomy. Nitric Oxide level was analyzed using the PCR-RFLP method. Data were analyzed using software STATA Intercooled Version 11.Results: NO level in endometriosis is higher than that in non-endometriosis and has a significant relationship with all the variables (age, parity, dysmenorrhea, dyspareunia, types of endometriosis, and grade of endometriosis).Conclusion: The NO level in endometriosis is higher than that in non-endometriosis. The distribution of the polymorphism of allele GG is greater than that in non-endometriosis. The existence of polymorphism GG caused a higher eNOS, increasing NO level, causing a decrease in fertility which derived from the degenera-tive oocyte.

The effect of sambiloto tablet (AS201-01) on placental Chondroitin Sulfate A (CSA) expression of pregnant mice infected by Plasmodium berghei Nasrul Wahdi; Widjiati Widjiati; Aty Widyawaruyanti; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 26 No. 2 (2018): August
Publisher : Universitas Airlangga

Objectives: To determine the effect of Sambiloto tablet (AS201-01) in reducing the placental Chondroitin Sulfate A (CSA) Expression of pregnant mice infected Plasmodiumberghei.Materials and Methods: Experimental study using 24 pregnant mice were divided into 4 groups with randomization. Uninfected group, the placebo group, the Sambiloto tablet (AS201-01) group and the DHP tablet (as a standart drug) group. The last three groups, were infected with P. bergheion day 9th of pregnancy, and the treatment was started at day 11th of pregnancy, and samples were terminated at day 15th of pregnancy by surgery. Placental sampling were stained with Tunnel assay to measure placental CSA antibodies.Results: The placental Chondroitin Sulfate A (CSA) expression. Uninfected group compared to Sambiloto tablet (AS201-01) groups was not significantly different (p>0.05), uninfected group compared with the other treatment groups differ meaningfully (p<0.05). Placebo group compared with all groups significantly different (p<0.05). Sambiloto tablet (AS201-01) group compared to uninfected group (p>0.05) was not significantly different, with another group was significantly different (p<0.05). DHP tablet group compared to all the groups was significantly different (p<0.05).Conclusion: Placental Chondroitin Sulfate A (CSA)expression of mice infected by Plasmodium berghei treated with Sambiloto tablet (AS201-01) lower than DHP tablet.

Combination of palonosetron-dexamethasone is more effective than ondansetron-dexamethasone as single cisplatin antiemetic chemotherapy Agung Sunarko Putra; Suhatno Suhatno
Majalah Obstetri dan Ginekologi Vol. 26 No. 2 (2018): August
Publisher : Universitas Airlangga

Objective: To know the efficacy differences between two groups of drug combination ondansetron-dexamethasone (A) and ondan-setron-dexamethasone (B) to prevent emetic rsponses after chemotherapy cisplatin administration (CINV).Materials and Methods: A prospective double blind randomized clinical trial study held in Dr. Soetomo General Hospital involving 66 subjects, devide into two groups randomly 33 patients each. One group receive palonosetron-dexamethasone combination therapy compare to ondansetron-dexamethasone combination as standart therapy in gynecologic oncology Dr. Soetomo Hospital in a control group as cisplatin chemotharapy CINV prophylaxis. The research was conducted from June till October 2014 in the Dr. Soetomo General Hospital-Surabaya. Assessment and measurement of the response of nausea and frequency of vomiting according Gralla scale, changes in plasma density and electrolyte serum (Na, K, and Cl) as a result of dehydration caused by nausea and vomiting, as well as counting the onset of nausea and vomiting occur.Results: There was significant differences between the results of the combination therapy compared ondansetron-dexamethasone to palonosetron-dexamethasone for nausea and vomiting (p=0,001). 31 subjects suffers nausea in ondansetron group, while 9 subjects suffers nausea in palonosetron group. Vomiting occurs in 17 subjects from ondansetron group, and only 1 subject from palono-setron group during study. Changes in plasma density significant in palonosetron group, and natrium in ondansetron group. For K and Cl not significantly difference in both groups before and after cisplatin chemotherapy administration.Conclusion: Palonosetron-dexamethasone combination is super-ior as cisplatin CINV prophylaxis in response to nausea and vomiting frequency, and also give longer protection compare to ondansetron-dexamethasone significantly. The plasma density and electrolyte serum changes are varied in numbers and also influenced by many factors including physical status and nutrition, also intake of each patients.

Effect of prenatal Mozart composition on Brain Derived Neurotrophic Factor expression in cerebrum and cerebellum of Rattus norvegicus offspring from Food Restriction 50 model Yulia Putri Permatasari; Widjiati Widjiati; Hermanto Tri Joewono
Majalah Obstetri dan Ginekologi Vol. 26 No. 1 (2018): April
Publisher : Universitas Airlangga

Objectives: To analyze the difference of BDNF expression on Rattus norvegicus offspring FR50 model in cerebrum and cerebellum between Mozart composition stimulation group and control.Materials and Methods: An analytical experimental study with single blind randomized post test only control group using animal subjects Rattus norvegicus FR50 model. This study was conducted at animal laboratory, Faculty of Veterinary Medicine, Airlangga University. Animal subjects were divided into Mozart music stimulation group and control. The BDNF expression was analyzed using comparison test, with significancy p<0,05.Results: There was no difference of BDNF expression on Rattus norvegicus offspring FR50 model between Mozart music stimu-lation group and control in cerebrum with p=0.495 (mean Mozart group 6.89+2.52 vs control 6.22+1.99), and cerebellum with p=0.146 (mean Mozart group 7.41+2.67 vs control 5.73+2.45).Conclusions: There was no difference of BDNF expression between Mozart composition stimulation group and control in the cerebrum and cerebellum of Rattus norvegicus offspring FR50 model.

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Jl. Airlangga No.4 - 6, Airlangga, Kec. Gubeng, Kota SBY, Jawa Timur 60115

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Jawa timur

INDONESIA