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Dental Journal (Majalah Kedokteran Gigi)
Published by Universitas Airlangga
ISSN : 19783728     EISSN : 24429740     DOI : -
Core Subject : Health,
The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.
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Articles 950 Documents
Dental measurements of Deuteromalayid Javanese students of the Faculty of Dentistry Airlangga University Myrtati Dyah Artaria; Bambang Soegeng Herijadi
Dental Journal (Majalah Kedokteran Gigi) Vol. 44 No. 3 (2011): September 2011
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (107.225 KB) | DOI: 10.20473/j.djmkg.v44.i3.p122-126

Abstract

Background: Dental anthropology is a new field of study in Indonesia, hence there are few numbers of research that can be found in this field. Knowledge in this field is needed due to the large area and diversity of the people. Moreover, knowledge regarding the possibility to differentiate the sexes of skeletons is still needed for the purpose of identification. Purpose: This research intended to study the differences in mesio-distal measurements of the teeth of Deuteromalayid Javanese males and females studying in the Faculty of Dentistry in Airlangga University. Methods: This study used mesiodistal metric dental data, using dental caliper, to test the existence of sexual dimorphism. Sample were teeth of freshman students of the Airlangga University, from 52 individuals comprising 26 males and 26 females Deuteromalayid originated from Java (Indonesia) studying in the Faculty of Dentistry Airlangga University. Measurements were not performed on damaged casts due to caries or other reasons. Differences between males and females were tested using independent t-test. Results: The mean of mesiodistal measurements in males and females differs, where the males have greater size of mesiodistal measurements. The results showed that there were significant differences between sexes in the sample, in all field of teeth except the second upper and lower premolars. Reverse sexual dimorphism-female teeth measurement is larger than those of males-has not been found in these samples. The result of this study revealed that the range of mesiodistal measurements of every tooth in males and females overlapped. Conclusion: It is concluded that teeth measurement of males is bigger than females, except maxillary and mandibular second premolars. Latar belakang: Antropologi dental adalah bidang studi baru di Indonesia, dan karenanya penelitian di bidang ini masih sedikit dijumpai di Indonesia. Apalagi masih dibutuhkan pengetahuan mengenai apakah jenis kelamin dapat dilihat dari geligi tengkorak manusia, untuk keperluan identifikasi. Tujuan: Tujuan penelitian ini adalah untuk mengetahui perbedaan ukuran mesiodistal gigi antara laki-laki dan perempuan Deuteromalayid dari Jawa. Metode: Penelitian ini menggunakan data pengukuran mesio-distal gigi untuk mengetahui apakah ada perbedaan antar jenis kelamin pada ukuran gigi mahasiswa Fakultas Kedokteran Gigi Universitas Airlangga keturunan Deuteromalayid dari Jawa. Penelitian ini merupakan penelitian tahap awal dengan jumlah sampel yang masih terbatas. Sampel diambil dari 52 orang individu yang bersedia dicetak giginya dengan jumlah 26 laki-laki dan 26 perempuan. Pengukuran dilakukan dari mesial ke distal gigi. Pengukuran tidak dilakukan mesial gigi yang mengalami kerusakan seperti misalnya karena karies atau aus yang parah. Signifikansi perbedaan antar jenis kelamin dianalisis menggunakan independent t-test. Hasil: Hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan antar laki-laki dan perempuan di semua jenis gigi, kecuali pada premolar ke dua atas dan bawah. ”Reverse sexual dimorphism” di mana rata-rata ukuran gigi perempuan lebih besar dari lakilaki, tidak ditemukan pada sampel ini. Pada penelitian ini meskipun dijumpai ”overlap” pada ukuran gigi laki-laki dan perempuan, tetapi sebagian besar rata-rata ukuran gigi berbeda secara bermakna antar kedua jenis kelamin pada sampel mahasiswa Fakultas Kedokteran Gigi Universitas Airlangga yang berasal dari Jawa keturunan Deuteromalayid. Kesimpulan: Dapat disimpulkan bahwa pengukuran gigi laki-laki lebih besar daripada perempuan, kecuali premolar kedua maksila dan mandibula.
Karakterisasi stem cell pulpa gigi sulung dengan modifikasi enzim tripsin (The characterization of stem cells from human exfoliated deciduous teeth using trypsin enzym) Tri Wijayanti Puspitasari; Tania Saskianti; Udijanto Tedjosasongko
Dental Journal (Majalah Kedokteran Gigi) Vol. 47 No. 2 (2014): June 2014
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.465 KB) | DOI: 10.20473/j.djmkg.v47.i2.p115-119

Abstract

Background: Now a days, treatment in dentistry, using tissue regeneration that based on the stem cells from human exfoliated deciduous teeth (SHED), grows rapidly. For several reason, the isolated and cultured SHED is difficult to be applied in Indonesia, therefore the modification is needed. This difficulties were caused by the pulp anatomy, the heterogeneous populations in the pulp chamber and the limitations of tools and materials at the laboratory. Purpose: This research was aimed to examine that the modifications of isolation and culture technique of SHEDs for characterization by using the marker of CD105. Methods: The research was experimental laboratory with the cross sectional design. The samples were the human exfoliated deciduous teeth from the children patients of Pediatric Dentistry Department of Universitas Airlangga Dental Hospital which matched the criteria. Dental pulps were isolated and cultured by using the modifications of Trypsin enzymes. Results: The healthy SHEDs could be produced from the modifications of isolation and culture and positively shown the expression of marker CD105 which were indicated by the fluorencent microscope. Conclusion: SHED which isolated and cultured by using the modified techniques, positively characterized by using marker CD105.Latar Belakang: Pengobatan kedokteran gigi berkembang dengan pesat terutama di bidang regenerasi jaringan berbasis Stem Cells from Human Exfoliated Deciduous Teeth (SHED). Di Indonesia, isolasi dan kultur SHED sulit sehingga perlu dilakukan modifikasi. Kendala ini muncul karena jaringan pulpa yang kecil, heterogen dan keterbatasan alat dan bahan di laboratorium. Tujuan: Penelitian ini bertujuan untuk meneliti modifikasi pada cara isolasi dan kultur SHED untuk karakterisasi menggunakan maker CD105. Metode: Jenis penelitian ini adalah eksperimental laboratoris dengan rancangan cross sectional. Sampel penelitian adalah gigi sulung dari pasien anak di Klinik Kedokteran Gigi Anak, Rumah Sakit Gigi dan Mulut Universitas Airlangga yang telah memenuhi kriteria. Pulpa gigi diisolasi dan dikultur dengan modifikasi enzim Trypsin. Hasil: SHED yang sehat hasil dari modifikasi teknik isolasi dan kultur positif menunjukkan ekspresi marker CD105 dengan berfluoresensi berwarna hijau dilihat melalui mikroskop fluoresen. Simpulan: SHED yang dikultur dan diisolasi dengan teknik modifikasi positif dikarakterisasi dengan marker CD105.
Effectivity of 0.15% benzydamine on radiation-induced oral mucositis in nasopharynx carcinoma Remita Adya Prasetyo
Dental Journal (Majalah Kedokteran Gigi) Vol. 44 No. 2 (2011): June 2011
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.104 KB) | DOI: 10.20473/j.djmkg.v44.i2.p88-92

Abstract

Background: Nasopharynx carcinoma is the most common malignant tumour in head and neck region. Radiotherapy is the first choice of treatment for nasopharynx carcinoma that had not been metastases. The most common oral complications in radiotherapy is mucositis (± 80%). 0.15% benzydamine hydrochloride (HCl) oral rinse can be used to prevent radiation-induced oral mucositis. Purpose: The aim of this research was to study the effectivity of 0.15% benzydamine HCl oral rinse for prevention of radiation-induced oral mucositis in nasopharynx carcinoma. Methods: Samples were divided into 2 groups. Group A was using 0.15% benzydamine HCl oral rinse for 10 days. Group B was using placebo oral rinse for 10 days. Evaluation was conducted 3 times: first day, fifth day and tenth day of radiotherapy. The scoring used Spijkervet’s mucositis α score. Results: Independent t test analysis for initial occurrence of oral mucositis showed no significant difference between 2 groups. Paired t test analysis showed significant difference between initial mucositis α score and mucositis α score in tenth day in each group. Independent t test analysis showed no significant difference in mucositis α score in tenth day between 2 groups. Conclusion: In conclusion 0.15% benzydamine HCl oral rinse was not effective to prevent radiation-induced oral mucositis in nasopharynx carcinoma.Latar belakang: Karsinoma nasofaring (KNF) merupakan tumor ganas terbanyak di daerah kepala-leher. Radioterapi merupakan terapi pilihan utama KNF yang belum mempunyai metastasis jauh. Komplikasi akibat radioterapi dalam rongga mulut yang terbanyak adalah mukositis (± 80%). Salah satu obat untuk pencegahan mukositis akibat radioterapi adalah benzydamine hydrochloride (HCl) 0,15%. Tujuan: Tujuan penelitian ini adalah untuk mempelajari efektivitas penggunaan obat kumur benzydamine HCl 0,15% sebagai pencegah mukositis akibat radioterapi pada karsinoma nasofaring. Metode: Sampel dibagi ke dalam 2 kelompok. Kelompok A yang menggunakan obat kumur benzydamine HCl selama 10 hari. Kelompok B menggunakan obat kumur plasebo selama 10 hari. Evaluasi dilakukan pada tahap awal, hari ke-5 radioterapi dan hari ke-10 radioterapi. Alat ukur adalah skor mukositis α Spijkervet. Hasil: Analisis Independent t-test menunjukkan awal terjadinya mukositis antara kedua kelompok tersebut tidak berbeda bermakna. Hasil uji t berpasangan antara skor mukositis α awal dengan skor mukositis α evaluasi II pada masing-masing kelompok tersebut menunjukkan perbedaan yang bermakna. Berdasarkan uji t, skor mukositis α evaluasi II antara kelompok A dengan B tersebut tidak berbeda bermakna. Kesimpulan: Disimpulkan bahwa obat kumur benzydamine HCl 0,15% tidak efektif sebagai pencegah mukositis akibat radioterapi pada penderita KNF.
Efek ekstrak daun singkong (Manihot utilissima) terhadap ekspresi COX-2 pada monosit yang dipapar LPS E.coli (The effect of Manihot utilissima extracts on COX-2 expression of monocytes induced by LPS E. coli) Zahara Meilawaty
Dental Journal (Majalah Kedokteran Gigi) Vol. 46 No. 4 (2013): December 2013
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (579.887 KB) | DOI: 10.20473/j.djmkg.v46.i4.p196-201

Abstract

Background: Periodontal disease is a common and widespread disease in the community. Gram negative bacteria have a role inperiodontitis. These bacteria secrete a variety of products such as endotoxin lipopolysaccharide (LPS), which causes the occurrenceof inflammation or infection. The body defense responses are neutrophils and mononuclear cells (monocytes and macrophages). Inresponse to defense mechanism, the body will be expressed enzyme cyclooxygenase (COX) which functions convert arachidonic acidto prostaglandins. Cassava leaf cells known to play a role in reducing inflammation, but the mechanism for inhibiting COX-2, is notknown. Purpose: The study was aimed to determine the effect of cassava leaf extract (Manihot utilissima) on expression of enzyme COX-2 in monocytes which were exposed by LPS E. coli. Methods: This study was in vitro experimental studies with the design of posttestonly control group design. The sample was the cassava leaves extract (Manihot utilissima) at concentration of 12.5 % and 25 %. Theexpression of COX-2 was determined by immunocytochemistry method. Isolated monocytes were incubated in cassava leaf extract, andthen exposed to LPS, after washing imunostaning procedure was performed using a monoclonal antibody (MAb) anti-human COX-2.The research data was the number of monocytes that express COX-2. Results: Expression of COX-2 in the group cassava leaf extractwas higher than the group that induced by LPS E. coli only. Conclusion: Cassava leaf extract did not inhibit the expression of COX-2in monocytes which were exposed by LPS E. coli.Latar belakang: Penyakit periodontal merupakan penyakit umum dan tersebar luas di masyarakat. Bakteri yang banyak berperanpada periodontitis adalah Gram negatif. Bakteri ini mengeluarkan berbagai produk antara lain endotoksin lipopolisakarida (LPS) yangmenyebabkan inflamasi atau infeksi. Respon pertahanan tubuh pertama adalah netrofil dan sel mononuklear (monosit dan makrofag).Pada respon pertahanan tubuh akan diekspresikan enzim siklooksigenase (COX) yang berfungsi mengubah asam arakidonat menjadiprostaglandin. Daun singkong diketahui berperan dalam menurunkan sel radang, tetapi mekanisme dalam menghambat COX-2, belumdiketahui. Tujuan: Penelitian ini bertujuan untuk meneliti ekstrak daun singkong terhadap ekspresi enzim COX-2 pada monosit yangdipapar LPS E. coli. Metode: Penelitian ini merupakan studi eksperimental in vitro dengan rancangan The posttest only control groupdesign. Sampel adalah ekstrak daun singkong (Manihot utilissima) dengan dosis 12,5% dan 25%. Ekspresi COX-2 diteliti denganmetode imunositokimia. Isolat monosit diinkubasi ekstrak daun singkong, kemudian dipapar LPS, setelah pencucian kemudian dilakukanprosedur imunostaning menggunakan antibodi monoklonal (Mab) anti human COX-2. Data penelitian adalah jumlah monosit yang mengekspresikan COX-2.Hasil: Ekspresi COX-2 pada kelompok ekstrak daun singkong lebih tinggi dibandingkan kelompok yang hanyadiinduksi LPS E.coli. Simpulan: Ekstrak daun singkong tidak menghambat ekspresi COX-2 pada monosit yang dipapar LPS E. coli.
Clinical consideration of thrombocytopenia in children S. Ratna Laksmiastuti
Dental Journal (Majalah Kedokteran Gigi) Vol. 43 No. 4 (2010): December 2010
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.854 KB) | DOI: 10.20473/j.djmkg.v43.i4.p163-167

Abstract

Background: Pediatric patient with the history of bleeding disorder as thrombocytopenia is considered as a clinical case in dentistry. The patient with platelet count below normal has potential risk of bleeding disorders. The situation would be more dangerous if the dentist could not identify the problem. Purpose: The aim of this review is to describe how a dentist must understand the step and management that should be performed in pediatric patient with history of bleeding disorder due to thrombocytopenia. Reviews: Bleeding disorders might be the result of thrombocytopenia, a condition that alter the ability of blood vessels, platelet and coagulation factors in normal hemostatic system. Thrombocytopenia is defined as a platelet count of less than normal (150.000/mm3–400.000/mm3). Etiology, risk factor and preventive method of thrombocytophenia are still unknown. Conclusion: It is concluded that special attention is needed for pediatric patient with thrombocytopenia. A dentist should understand well about this disorder on how to take the history, to do clinical examination, to establish the diagnosis and to decide treatment plan as well as to consult to related collongues.Latar belakang: Penderita anak-anak dengan riwayat gangguan perdarahan yang ditandai dengan adanya trombositopenia merupakan masalah klinis yang ditemukan dalam bidang kedokteran gigi. Beberapa perawatan di bidang kedokteran gigi beresiko menimbulkan terjadinya perdarahan. Keadaan akan berbahaya bila dokter gigi tidak dapat mengidentifikasi masalah. Tujuan: Artikel ini menunjukkan pentingnya seorang dokter gigi memahami dan mengetahui langkah dan tindakan apa yang harus dilakukan, bila suatu saat menghadapi penderita anak-anak dengan riwayat gangguan perdarahan akibat trombositopenia. Review: Gangguan perdarahan adalah suatu kondisi terjadinya penurunan kemampuan dari pembuluh darah, platelet, dan faktor pembekuan pada fungsi normal hemostasis. Trombositopenia adalah jumlah trombosit/platelet dalam darah berada pada jumlah di bawah normal (150.000/mm3–400.000/mm3), yang dapat mengakibatkan terjadinya gangguan perdarahan. Penyebab, faktor risiko dan cara pencegahan kasus trombositopenia belum diketahui dengan pasti. Kesimpulan: Diperlukan perhatian khusus pada penderita anak yang mengalami gangguan perdarahan. Seorang dokter gigi harus mengetahui dengan baik bagaimana menggali informasi tentang riwayat penyakit, melakukan pemeriksaan klinis yang tepat, menegakkan diagnosis, menentukan rencana perawatan serta melakukan rujukan bila diperlukan.
Restorasi mahkota logam dengan pasak fiber komposit pada molar permanen muda (Metal crown restoration with fiber composite post in young permanent molar) Theresia Dhearine Pratiwi; Mochamad Fahlevi Rizal
Dental Journal (Majalah Kedokteran Gigi) Vol. 46 No. 3 (2013): September 2013
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (609.884 KB) | DOI: 10.20473/j.djmkg.v46.i3.p162-166

Abstract

Background: The first permanent molar has a high prevalence of caries with the most rapid progression in the first two years after eruption. The destruction can extend to the pulp and require endodontic treatment. After endodontic treatment the teeth should have a final restoration due to the possibilities of fracture. The teeth with a few remaining tissue need a restoration such as crown with post and core support. Fiber composite post is widely used today because it has a similar modulus elasticity as dentin. Purpose: The case report was aimed to share the endodontic treatment which was followed by fiber composite post and metal crown insertion on young permanent molar. Case: An 11 years old girls was referred to Pediatric Dentistry clinic at Universitas Indonesia Dental Hospital due to caries #36 that extend to the pulp. Case management: Endodontic treatment with metal crown supported by fiber composite post and composite core was done as final restoration. One month after procedure there was no subjective complaints or inflammation. Conclusion: The case report showed that endodontic treatment followed by fiber composite post and metal crown insertion could be done succesfully on young permanent molar of 11 years old patient.Latar belakang: Gigi molar pertama permanen muda (M1) merupakan gigi dengan angka kejadian karies yang tinggi dengan kerusakan paling cepat terjadi pada dua tahun pertama setelah gigi tersebut erupsi. Kerusakan tersebut dapat mencapai pulpa sehingga diperlukan perawatan endodontik. Gigi yang sudah dirawat memerlukan restorasi akhir yang baik, karena kemungkinan terjadi fraktur. Sisa jaringan gigi yang sedikit membutuhkan restorasi akhir berupa mahkota tiruan dengan dukungan pasak dan inti. Pasak fiber komposit merupakan pasak yang saat ini sering digunakan karena memiliki keunggulan modulus elastisitas yang menyerupai dentin. Tujuan: Tujuan penulisan laporan kasus ini adalah untuk melaporkan perawatan endodontik yang diikuti dengan pemasangan pasak fiber komposit dan mahkota logam pada molar pertama permanen muda. Kasus: Anak perempuan usia 11 tahun dirujuk ke klinik Kedokteran Gigi Anak Rumah Sakit Gigi dan Mulut Universitas Indonesia dengan kerusakan gigi #36 mencapai pulpa. Tatalaksana kasus: Perawatan endodontik dengan restorasi akhir mahkota tiruan tuang logam dengan dukungan pasak fiber komposit dan inti resin komposit. Pada kontrol setelah 1 bulan tidak didapatkan keluhan subjektif serta kondisi peradangan Simpulan: Laporan kasus ini menunjukkan bahwa perawatan endodontik yang diikuti dengan pemasangan pasak fiber komposit dan mahkota logam dapat dilakukan dengan baik pada molar pertama permanen muda dari pasien berusia 11 tahun.
The effect of monofluorophosphate implant in white rat mothers towards the level of fluor in the incisors of their young babies (Rattus-rattus) Widjijono Widjijono
Dental Journal (Majalah Kedokteran Gigi) Vol. 43 No. 2 (2010): June 2010
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (190.255 KB) | DOI: 10.20473/j.djmkg.v43.i2.p72-75

Abstract

Background: Fluoride has been widely used in the prevention of dental caries for a long time. To prevent dental caries, fluoride must be induced in low amount at high frequency. Inducing it through implantation process even make slow release of small concentration of fluoride. Purpose: The aim of this research was to analyze whether the induction of monofluorophosphate (MFP) implant into the white rat mothers affects the level of fluoride in the incisors of their young babies. Method: The objects of the research were twenty white rat mothers in two days of pregnancy which then were divided into four groups (n=5). First, those mothers have been induced with implant under their back skin until their born young babies in the age of 35 days (n=5). The level of fluoride in the incisors of those young babies then is measured with Potentiometer. The obtained data were finally analyzed with One-Way ANOVA test and continued by with LSD test (p=0.05). Result: The result of this research showed that the means of the fluoride level in the incisors of those babies divided into those four groups in series were about 11956.16±201.35 ppb (K), 27328.04±234.56 ppb (P1), 37267.21±248.86 ppb (P2), and 18103.50±267.11 ppb (P3). The result of ANOVA test then showed that the induction of various MFP implant levels significantly affected the level of fluoride in the incisors of the babies. The mean differences among the treatment groups after being tested with LSD 0.05 were also significant. Conclusion: The finding confirm that the significant increasing of the optimal fluoride retention in the incisors of white rat babies can be achieved with the induction of fluoride with MFP ions implant in about 52.98 mg.Latar belakang: Pencegahan karies gigi menggunakan senyawa fluor telah banyak dilakukan dan berlangsung dalam jangka waktu lama. Pemberian fluor dalam jumlah rendah dan frekuensi tinggi merupakan pemenuhan kebutuhan pencegahan karies gigi. Pemberian dengan cara implantasi memberikan keluaran fluor jumlah kecil dan waktu lama. Tujuan: Penelitian ini bertujuan untuk mengetahui apakah induk tikus yang diberi implan-MFP berpengaruh terhadap kandungan fluor gigiseri anak tikus. Metode: Subjek penelitian adalah 20 ekor induk tikus putih bunting 2 hari dibagi 4 kelompok (n=5). Induk diberi implan pada bawah-kulit punggung hingga anak tikus lahir dan pada umur 35 hari (n=5). Kandungan fluor pada gigi seri anak tikus diukur menggunakan Potensiometer. Data yang diperoleh dianalisis dengan Anova 1 jalur dilanjutkan uji LSD (p=0,05). Hasil: penelitian menunjukkan rerata fluor gigiseri anak tikus berturut-turut sebesar: 11956,16±201,35 ppb (K), 27328,04±234.56 ppb (P1), 37267,21±248.86 ppb (P2), dan 18103,50±267,11 ppb (P3). Hasil: Anava membuktikan bahwa ada pengaruh bermakna akibat variasi kadar MFP dalam implan terhadap kandungan fluor gigi anak tikus. Beda rerata antar kelompok perlakuan diuji dengan LSD0,05 memperlihatkan perbedaan bermakna pada semua kelompok. Kesimpulan: Penelitian dapat disimpulkan bahwa kenaikan secara bermakna terhadap retensi fluor optimal dalam gigiseri tikus putih pada pemberian fluoridasi menggunakan implan dengan muatan MFP: 52,98 mg.
The role of inducible Nitric Oxide Synthase in teeth periapical lesions immunopathogenesis caused by Enterococcus faecalis Tamara Yuanita; Latief Mooduto; Kuntaman Kuntaman
Dental Journal (Majalah Kedokteran Gigi) Vol. 46 No. 1 (2013): March 2013
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (198.797 KB) | DOI: 10.20473/j.djmkg.v46.i1.p14-17

Abstract

Background: Periapical lesions, are characterized by an immune response to the invading bacteria consequences periapical bone destruction. In root canal treatment failure was found Enterococcus faecalis (E. faecalis) as most species. iNOS found an important role in protection against infection, plays vital roles in fighting pathogens and contributing to disease pathology. Purpose: This study was to observed the role of iNOS in teeth periapical lessions immunopathogenesis caused by E. faecalis. Methods: The randomized post-only control group design used in this study, This study used 24 Wistar rats, were divided into three groups (each group consisted of 8 rats), as negative controls group is a normal teeth, in the positive controls group was made by drilling the upper right first molar to penetrate the dental pulp and was induced with 10µl BHI-b then filled with Glass Ionomer Cement (GIC) and the treatment group, after drilling the teeth, then inoculated with E. faecalis ATCC 29212 106 CFU into 10µl BHI-b then filled with GIC to prevent contamination. It takes 21 days to get periapical lesions and rat were sacrificed, and then the expression of iNOS was measured. Results: Statistical analysis using ANOVA found a significant differenced between control and treatment groups (p<0.05). Conclusion: This study concluded that iNOS role in teeth periapical lesions immunopathogenesis caused by E. faecalis.Latar belakang: Lesi periapikal merupakan hasil suatu respon imun untuk melawan invasi bakteri yang mengakibatkan destruksi tulang periapikal. Pada perawatan saluran akar yang mengalami kegagalan ditemukan Enterococcus faecalis sebagai spesies terbanyak. iNOS berperan penting untuk proteksi terhadap bakteri, mempunyai peran yang vital untuk melawan patogen dan berkonstribusi secara patologik untuk menyebabkan suatu penyakit. Tujuan: Penelitian ini bertujuan untuk mengobservasi peran iNOS secara imunohistokimia pada lesi periapikal tikus Wistar. Metode: Penelitian ini menggunakan disain randomized post-only control group, digunakan 24 ekor tikus Wistar yang dibagi menjadi tiga kelompok yang masing-masing terdiri dari 8 ekor tikus, sebagai kelompok kontrol negatif adalah gigi normal, pada kelompok kontrol positif dilakukan pengeboran pada gigi molar pertama rahang atas sampai menembus pulpa kemudian diinduksi 10µl BHI-b kemudian ditumpat (Glass Ionomer Cement) GIC dan pada kelompok perlakuan, setelah dilakukan pengeboran dilakukan induksi E. faecalis ATCC 29212 sebanyak 106 CFU ke dalam 10 µl BHI-b kemudian ditumpat GIC untuk mencegah kontaminasi. Diperlukan waktu 21 hari untuk mendapatkan lesi periapikal pasca perlakuan kemudian tikus dikorbankan lalu dihitung sel-sel yang mengekspresikan iNOS. Hasil: Analisis menggunakan ANAVA membuktikan bahwa ada perbedaan yang bermakna antara kelompok kontrol dan kelompok perlakuan (p<0,05). Kesimpulan: iNOS berperan pada imunopatogenesis lesi periapikal gigi akibat E. faecalis.
Relationship between trauma mechanism and etiology on mandibular fracture patterns Fakhrurrazi Fakhrurrazi
Dental Journal (Majalah Kedokteran Gigi) Vol. 43 No. 1 (2010): March 2010
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (231.653 KB) | DOI: 10.20473/j.djmkg.v43.i1.p1-5

Abstract

Background: Mandibular fracture occurs more commonly than maxillary fracture because of its prominent position and its arrow arch like bone anatomy. Many factors may cause mandibular fracture. Motorcycle accident is the main etiology of mandibular fracture in the world. Based on the literature, 43% mandibular fractures are caused by motorcycle accident, 34% by violence, 7% by accident at work, 7% by fall, 4% by sports and the others were caused by various things. Purpose: The purpose of this study was to know the relation between the etiology and mechanisms of trauma and the patterns of mandibular fracture at Hasan Sadikin Hospital, Bandung, from January 2006 to October 2007. Method: The study was taken on patients with mandibular fractures who came to Hasan Sadikin Hospital Bandung. The data were taken retrospectively by documenting the etiologies of mandibular fracture, the mechanisms of fracture, and the location of mandibular fracture. The data were analyzed with Chi Square statistic test. Result: The result showed that There were 83 mandibular fractures. The mandibular fracture more commonly attacks men about 77%, and women about 22.9%. Mandibular fracture occurs more often between the age group of 21-30 years old, about 31 people (37.3%). Mandibular fracture was mostles often caused by motorcycle accident, affecting about 71 people (85.5%). Parasymphysis fracture is the most common fracture location among mandibular fracture cases, about 47 people (56.6%). Conclusion: It can be concluded that there is no significant relationship between the etiology and mechanisms of trauma and the pattern of mandibular fracture.Latar belakang: Fraktur mandibula lebih sering terjadi dibandingkan dengan fraktur maksilla karenaposisinya yang lebihprominen dan bentuk anatomi tulang seperti busur panah. Banyak faktor yang dapat menyebabkan terjadinya fraktur mandibula. Kecelakaan kendaraan bermotor merupakan etiologi utama penyebab fraktur mandibula di dunia. Literatur menyebutkan bahwa 43% fraktur mandibula disebabkan oleh kecelakaan kendaraan bermotor, 34% disebabkan oleh kekerasan, 7% kecelakaan kerja, 7% akibat jatuh, 4% pada kecelakaan olahraga dan sisanya oleh bermacam-macam sebab lainnya. Tujuan: penelitian ini untuk mengetahui apakah ada hubungan antara etiologi dan mekanisme trauma dengan pola fraktur mandibula pada penderita fraktur mandibula di Rumah Sakit Hasan Sadikin Bandung dari bulan Januari 2006 sampai Oktober 2007. Metode: Penelitian dilakukan pada pasien dengan fraktur manibular yang datang ke Rumah Sakit Hasan Sadikin Bandung. Data dikumpulkan secara retrospektif dengan cara mencatat etiologi,mekanisme, dan lokasi terjadinya fraktur mandibula. Data dikumpulkan dan dikelompokkan kemudian dianalisis dengan uji statistik Chi-square. Hasil: Dari hasil didapatkan 83 kasus fraktur mandibula. Fraktur mandibula lebih sering terjadi pada laki-laki yaitu sebanyak 77% dibandingkan wanita 22,9%. Fraktur mandibula sering terjadi pada usia 21-30 tahun, yaitu sebanyak 31orang (37,3%). Fraktur mandibula lebih banyak disebabkan tabrakan motor yaitu 71 orang (85,5%). Fraktur parasimfisis merupakan yang terbanyak yaitu 47 orang (56,6%). Kesimpulan: Penelitian ini dapat disimpulkan bahwa antara etiologi dari fraktur mandibula, mekanisme trauma dengan pola fraktur mandibula tidak terdapat hubungan yang bermakna.
Pomegranate juice (Punica granatum) as an ideal mouthrinse for fixed orthodontic patients Haryono Utomo; Kimberly Clarissa Oetomo
Dental Journal (Majalah Kedokteran Gigi) Vol. 45 No. 4 (2012): December 2012
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (424.445 KB) | DOI: 10.20473/j.djmkg.v45.i4.p221-227

Abstract

Background: Prevention of caries as well as periodontal disease is mandatory during orthodontic treatment. Nevertheless, the use of antiseptic mouthrinse is contraindicated for prolonged use. Pomegranate juice is a polyphenol-rich juice with high antioxidant capacity as well as antimicrobial properties. It has been shown to exert beneficial characteristics for orthodontic patients such as antioxidant and anti inflammatory effects. Moreover, it contained fluoride and phosphorous which are cariostatic. Previous study in fixed orthodontic patients revealed that rinsing with this juice showed reduced dental plaque and superior compared with chlorhexidine. If it has unwanted effect by reducing pro-inflammatory reaction that also needed in orthodontic movement is not clearly understood. Purpose: The aim of the present review was to discuss the beneficial and unwanted effect of pomegranate juice mouthrinse towards orthodontic treatment. Reviews: Pomegranate has antimicrobial activity, its methanolic skin extract is the most potent followed by seed juice. Nevertheless, seed juice is not only tastier, easier to make but also has mild antimicrobial potency which is beneficial for long-term use. Healthy periodontal tissue is preferable for orthodontic movement since it resulted in less unwanted bone resorption. Conclusion: Regarding its beneficial effect and safety of pomegranate juice if use daily mouthrinse in fixed orthodontic patients, it could be proposed as an ideal long term use mouthrinse for fixed orthodontic patients. However, further researches should be done to verify this concept.Latar belakang: Pencegahan karies dan penyakit periodontal sangat penting dalam perawatan ortodontik. Walaupun demikian, penggunaan obat kumur antiseptik jangka panjang merupakan kontraindikasi. Jus buah delima sangat kaya akan polifenol dengan kemampuan antioksidan yang tinggi disertai kemampuan antimikroba. Beberapa penelitian telah menunjukkan dampak menguntungkan pada pasien ortodonti, yaitu sebagai antioksidan dan anti radang. Selain itu juga mengandung fluor dan fosfor yang bersifat kariostatik. Penelitian terdahulu pada pasien ortodonti cekat menunjukkan penurunan plak gigi yang lebih banyak dibanding dengan klorheksidin. Akan tetapi, apakah juga menyebabkan dampak merugikan yaitu mengurangi reaksi keradangan yang juga penting bagi pergerakan ortodonti masih belum jelas. Tujuan: Membahas dampak menguntungkan maupun merugikan jus buah delima pada perawatan ortodonti. Tinjauan pustaka: Buah delima merupakan antimikroba, ekstrak dari kulit yang mengandung metanol adalah paling kuat diikuti jus biji delima. Akan tetapi, jus biji lebih enak rasanya, mudah dibuat dan merupakan antimikroba ringan sehingga menguntungkan untuk pemakaian jangka panjang. Jaringan periodontal yang sehat diperlukan untuk pergerakan ortodonti karena dapat mengurangi resorpsi tulang. Kesimpulan: Berdasarkan dampak menguntungkan dan keamanan jus buah delima bila digunakan tiap hari, bahan ini dapat diusulkan sebagai obat kumur jangka panjang yang ideal untuk pasien ortodonti cekat. Walaupun begitu, penelitian lebih lanjut harus dilakukan untuk verifikasi konsep ini.

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