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Dental Journal (Majalah Kedokteran Gigi)

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Published by Universitas Airlangga

ISSN : 19783728 EISSN : 24429740 DOI : -

Core Subject : Health,

Dentistry

The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.

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Articles 964 Documents

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The role of Msx1 and Pax9 in pathogenetic mechanisms of tooth agenesis Yani Corvianindya Rahayu; dyah Setyorini
Dental Journal (Majalah Kedokteran Gigi) Vol. 42 No. 3 (2009): September 2009
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Tooth agenesis is one of the most common developmental anomalies in human, which one or a few teeth are absent because they have never formed, may cause cosmetic or occlusal harm, while severe agenesis which are relatively rare require clinical attention to support and maintain the dental function. Molecular studies have demonstrated that tooth development is under strict genetic control. Purpose: This article want to review the genetic regulating that are responsible for tooth agenesis especially the role of Msx1 and Pax9 in pathogenetic mechanisms of tooth agenesis. Review: Tooth agenesis is a consequence of a qualitatively or quantitatively impaired function of genetic networks, which regulate tooth development. Mutations in Msx1 and Pax9 genes are dominant for tooth agenesis in humans. The Pax9 gene, which codes for a paired domain-containing transcription factor that plays an essential role in the development of mammal dentition, has been associated with selective tooth agenesis in humans and mice. Conclusion: Reduced amount of functional Msx1 or Pax9 protein in the tooth forming cells is able to cause severe and selective tooth agenesis. There are differences in the frequency of agenesis of specific teeth associated with the defects in Msx1 and defects in Pax9.

The role of microendodontics in treating mandibular second molar with five canals Harry Huiz Peeters
Dental Journal (Majalah Kedokteran Gigi) Vol. 42 No. 1 (2009): March 2009
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Finding the incidence of anatomical variation in daily practice becomes more frequent due to the development of diagnostic tools such as microscopes and ultrasonic devices. Therefore, a thorough understanding of the normal anatomy of canals and its variations in root canal treatments would be helpful in achieving the desired result. The usual root configuration of a mandibular second molar is two separate roots, distal and mesial, of which the distal root usually has one canal and the mesial root two canals. The incidence of 4 distinct root canals in the distal root of C-shaped orifices is a rare phenomenon that is reported in literature. Purpose: To understand the role of microendodontics in trating mandibulary second molar with five canals. Case: This case shows how to locate and manage a rare anatomical variation of mandibular second molar with 4 distinct root canals in the distal aspect of a C-shaped orifice successfully. Case Management: The anatomical variation was overcome with the help of diagnostic tools such as microscopes and ultrasonic tips. Conclusion: The successful treatment of this case demonstrates the necessity for awareness of the presence of additional canals and abnormal morphology of the canals. Besides that the operator’s perseverance and patience as well as sophisticated diagnostic tools, such as the dental operating microscopes and ultrasonic tips, have an important role in treating unusual configurations of root canals.

Epulis and pyogenic granuloma with occlusal interference Widowati Witjaksono; Ban Tawfeek Shareff Al Ani
Dental Journal (Majalah Kedokteran Gigi) Vol. 38 No. 2 (2005): June 2005
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

In dental clinic of Hospital University Science Malaysia (HUSM), there were cases with Localized Gingival Enlargement (LGE) in the oral cavity with occlusal interference. In this study, three cases were observed. They were a 13 - year- old female with fibrous lge around 31 and 32 with occlusal interference in protrusive movement due to X bite, a 15 - year – old female with pyogenic granuloma near 11 & 21 with occlusal interference due to deep bite; and a 24 – year – old female who was eight months in pregnancy with pyogenic granuloma on the 34-35 and severe generalized pregnancy gingivitis with occlusal interference in centric occlusion and lateral movement. Clinical and histopathological diagnosis of the first case showed fibrous epulis, whereas the second and third cases disclosed pyogenic granuloma. Chronic trauma of the gingiva due to occlusal interference was assumed to be the cause of those LGE in case 1 and 2, while in case 3 poor oral hygiene and chronic trauma were assumed to be the etiologic factors.

Stimulation of type I collagen activity in healing of pulp perforation Sri Kunarti
Dental Journal (Majalah Kedokteran Gigi) Vol. 41 No. 4 (2008): December 2008
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: TGF-β1 is a connective tissue stimulant, potential regulator for tissue repair, and promoter in wound healing. The healing of pulp perforation is decided by quantity and quality of new collagen deposition. TGF-β1 upregulates collagen transcription. However, after several weeks production of type I collagen synthesis is stopped and enzymatic degradation of collagen matrix will occur. Purpose: Observe synthesis type I collagen during the process of pulp perforation healing in 7, 14, and 21 days after being treated using TGF-β1. Methods: This research in vivo from orthodontic patients indicated for premolar extraction, between ages 10–15 years. A class V cavity preparation was created in the buccal aspect 1 mm above gingival margin until pulp exposure. Cavity was irrigated slowly with saline solution and dried with a sterile small cotton pellet. The sterile absorbable collagen membrane used, soaked with 5 μl of TGF-β1. It was covered by teflon pledge to separate from glass ionomer cement as restoration. Evaluated on day 7th, 14th, and 21st. All samples were extracted and prepared for immunohystochemical examination. Result: Data were analyzed by t-test. There was significant difference in synthesis type I collagen compared between 7–14 days and 7–21 days after treatment by TGF-β1 also Ca(OH)2. There was significant difference compared between TGF-β1 and Ca(OH)2 in 14–21 days after treatment (means TGF-β1 > Ca(OH)2). Conclusion: Elevation of synthesis type 1 collagen by TGF-β1 in 20 mg/ml.

The effect of Psidium guajava Linn leaf extract on Candida albicans adherence and the transversal strength of acrylic resin Amiyatun Naini; Sherman Salim
Dental Journal (Majalah Kedokteran Gigi) Vol. 41 No. 1 (2008): March 2008
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Denture stomatitis is an inflammation of oral cavity due to removable denture wearing. Prevention of denture stomatitis can be effectively done by using mouth rinsing. Currently, Indonesian government is actively promoting traditional herbal medicine as an alternative medicine such as Psidium guajava Linn leaf which has an anti bacterial and anti fungal ability. The purpose of this study was to know the effective concentration and soaking duration to reduce Candida albicans without lowering transversal strength of acrylic resin. This experimental laboratory study was using heat cured acrylic resin plate without surface polishing. The concentration of Psidium guajava Linn leaf extract used in this study were 32%, 34%, 36%, and 38% respectively with 15 minutes, 30 minutes, 1 hour and 8 hours soaking duration. The transversal strength was measured in the same concentration with 2 days, 10 days and 60 days soaking duration. Sterile aquadest was used as control. Two direction ANOVA and LSD test were used in data analysis. The result showed significant difference in the number of Candida albicans colony among concentrations and soaking durations. Significant difference was also found in transversal strength among concentrations and soaking durations. It is concluded that the extract of Psidium guajava Linn leaf in 38% concentration with 8 hours soaking duration will lower the Candida albicans colony, whereas 38% concentration with 60 days soaking duration will lower the transversal strength but it is still above the standard value.

Sitotoksisitas bahan restorasi cyanoacrylate pada variasi perbandingan powder dan liquid menggunakan MTT assay (Cytotoxicity of the cyanoacrylate restoration material with variation of powder and liquid ratio by using MTT assay) Asti Meizarini
Dental Journal (Majalah Kedokteran Gigi) Vol. 38 No. 1 (2005): March 2005
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

The requirements for dental material include not toxic, not irritant, no carcinogenic potential, nor cause an allergic response with the use in oral cavity. The cyanoacrylate restoration material has certain substance that can be toxic. Because of the ratio amount of powder and liquid is not known, it can lead the restoration more toxic. The purpose of this study was to know the cytotoxicity of the cyanoacrylate restoration material with different variation of powder and liquid ratio using MTT assay. Six cylinder samples of 5 mm in diameter and 2 mm in thickness were used for each group of 1:1.00; 1:0.75; 1:0.50 powder and liquid ratio of cyanoacrylate restoration materials. Each of samples was immersed in eppendorf micro tubes consisting of media culture. After 24 hour, the immersion of media culture was used to investigate the cytotoxic effect to BHK-21 cell lines by MTT assay method. The density of optic formazan indicated the amount of living cells. All data were statistically analyzed by one-way ANOVA and HSD. The results showed that the percentage of living cells amount of powder and liquid ratio 1:1.00; 1:0.75; 1:0.50 were 98.59%; 95.76%; 94.92% respectively. There was a significant difference between 1:1.00 and 1:0.50 group ratio. The conclusion was that the cytotoxicity between 1:1.00 and 1:0.50 powder and liquid ratio of cyanoacrylate restoration materials in this study decreased.

Sealing ability of hydroxyapatite as a root canal sealer: in vitro study Widowati Witjaksono; Lin Naing; Ema Mulyawati; AR. Samsudin; Mon Mon Tin Oo
Dental Journal (Majalah Kedokteran Gigi) Vol. 40 No. 3 (2007): September 2007
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Hydroxyapatite (HA) is the most thermodynamically synthetic calcium phosphate cement, and has indicated useful as a sealer because can seal a furcation perforation, is shown to be biocompatible and also has potential to promote the healing of bone in endodontic therapy. The objective of this study is to determine the sealing ability of HA produced by School of Engineering, Universiti Sains Malaysia (USM) when used as a sealer in root canal obturation, compare with Tubli-seal (Zinc-Oxide base) and Sealapax (Calcium Hydroxyde base) sealers. Forty five single rooted human anterior teeth were instrumented and randomly divided into three experimental groups of 15 teeth each. All teeth in the experimental groups were obturated with laterally condensed gutta percha technique. Teeth in the first group were sealed using Zinc-Oxide (ZnO) based sealer and those of second group using Calcium Hydroxide (CaOH) based root canal sealer. Third experimental group was sealed using HA from School of Engineering USM. Teeth were then suspended in 2% methylene blue. After this, teeth were demineralized dehydrated and cleared. Linear dye penetration was determined under magnifying lense with calibrated eye piece. Statistical analyses of the linear dye penetration were performed with Kruskal Wallis test. The intergroup comparison between HA and ZnO groups and CaOH groups were analyzed by Mann-Whitney test. The dye penetration for group which were sealed with HA exhibited the lowest penetration and it showed that there was a statistically significant difference both between HA and ZnO groups and also between HA and CaOH groups (p < 0.001).In conclusion, it was found that value added HA based endodontic material which were produced by USM can be used as a root canal sealing materials when it used in combination with epoxy resin since it leaked comparatively less as compared to ZnO and CaOH sealers. Before reaching a definitive conclusion, this material requires further extensive exploration both clinically and in vitro.

Experimental comparative study and fracture resistance simulation with irrigation solution of 0.2% chitosan, 2.5% NaOCl and 17% EDTA Ernani Ernani; Tri Murni Abidin; Indra Indra
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 3 (2015): September 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Preparation in endodontic need irrigation materials as root canal debridement and disinfectant. However, irrigation materials is one of the factors that influence the tendency of fracture. Purpose: This study was aimed to see the resistance and fracture distribution if teeth irrigated with high molecular horseshoe crab chitosan at 0.2% concentration, 2.5% NaOCl solution and 17% EDTA solution in endodontic treatment with finite element method (FEM) simulation study and experimental studies. Method: Endodontic treatment performed on 28 maxillary premolars with group A: irrigation solution of 17% EDTA and 2.5% NaOCl solution; group B: 2.5% NaOCl irrigation solution; group C: 2.5% NaOCl irrigation solution and 0.2% chitosan solution; group D: 0.2% chitosan solution irrigation. Final restoration was done using prefabricated glass fiber post. Cementation of post using resin cement then restored with direct composite resin restorations. Pressure test was performed with a Universal Testing Machine with a speed of 0.5 mm/min until fracture occurred. A three dimensional finite element analysis was performed for total deformation, equivalent (von-mises) stress, and equivalent elastic strains. Result: Anova test showed significant differences in fracture resistance (p<0.05) in stroke difference between four groups. Based on the results of the analysis of post-hoc Bonferroni test and LSD, fracture resistance was significantly different between group A (1038.4±201.6) with group C (1515.6±243.3). Kruskal-Wallis test showed no significant difference in the distribution of fractures among the four groups (p>0.05). Statistical analysis showed no significant difference (p>0.05) between the results of experiment and FEM analysis results using the t-test. Conclusion: The results of this study demonstrated that there was effect of the use of high molecular 0.2% chitosan as a combined irrigation with NaOCl, but did not affect the fracture pattern distribution of endodontically treated teeth both experimentally and FEM analysis test.

p53-protein over-expression and gene mutational of oral carcinoma in-situ Mei Syafriadi; Takashi Saku
Dental Journal (Majalah Kedokteran Gigi) Vol. 40 No. 2 (2007): June 2007
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

We had been reported histological types of oral carcinoma in-situ (oral CIS), such as basaloid, verrucous, and acanthothic/ atrophic types. We considered that they have different histological appearance influenced by molecular behavior. To understand the molecular behavior of them we examined p53 exon 4–8 gene mutation and their protein expression. Using 35 cases formalin-fixed paraffin sections of oral CIS and 10 cases of mild and moderate squamous epithelial displasia (SED) as a control were subjected to p53 immunohistochemistry. In the next step all cases were subjected to p53 gene mutations analysis by laser capturing microdissection and direct sequencing of PCR product for exon 4–8. Showed that p53-protein over-expression were found in basal layer of SED and the p53 protein over-expression were confined in the whole layer of CIS-basaloid type, basal and parabasal layers of CIS-verrucous type, and sporadically in the basal layer of CIS-acanthothic type. Mutational analysis for p53 gene showed 43% of total cases of CIS had p53 gene mutation therefore CIS-basaloid type had mutations more frequently than the other types and mutation in exon 8 more dominant than other exons, which had some common mutation at codons 196, 248, 282, 291, and 306, while no particular mutations were found in control (SED).Our criteria to diagnose several types of oral carcinoma in-situ by p53 protein expression and mutational analysis could be used to understand molecular behavior of CIS.

Early detection and treatment of Speckled leukoplakia Selviana Tampoma; Iwan Hernawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 49 No. 1 (2016): March 2016
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Leukoplakia is one of potentially malignant disorders that can be found on oral mucosa. Speckled leukoplakia is a rare type of leukoplakia with a very high risk of premalignant growth. Approximately 3 % of worldwide population has suffered from leukoplakia, 5-25% of which tend to be malignant leukoplakia. Purpose: This case report was aimed to discuss about early detection of speckled leukoplakia as one of potentially malignant disorders. Case: A 62 year old male patient came with chief complaint of bald and painful tongue since one month ago. The patient has a history of allergic reaction, hypertension, uric acid, and hepatitis B. He had been a heavy smoker since young until 10 years ago. Intra oral examination showed a firm, rough, non scrapable white plaque lesion with a size of 1 x 1.5 cm, surrounded by painful erosion with diffuse boundary. Case Management: Based on cytology examination, the patient was reffered to oncologist to get an excisional biopsy. Next, the patient succesfully underwent the excisional biopsy and came for control. The results showed the healing process of the lesion with a minimal complaint of bald tongue, especially when eating spicy or hot meal. To improve healing process, the patient then was given an antibacterial mouth rinse containing zinc and mulvitamin. Conclusion: Speckled leukoplakia could show high malignant transformation rate, therefore, early detection and treatment are necessary.

Page 43 of 97 | Total Record : 964

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Saka Winias

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dental_journal@yahoo.com

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Location
Kota surabaya,

Jawa timur

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Saka Winias

Contact Email saka.winias@gmail.com

Phone -

Journal Mail Official dental_journal@yahoo.com

Editorial Address -

Location Kota surabaya, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Saka Winias

Contact Email
saka.winias@gmail.com

Phone
-

Journal Mail Official
dental_journal@yahoo.com

Editorial Address
-

Location
Kota surabaya,

Jawa timur

INDONESIA