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The Correlation of Treatment Adherence with Clinical Outcome and Quality of Life in Patients with Type 2 Diabetes Syaiful Katadi; Tri Murti Andayani; Dwi Endarti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (305.925 KB) | DOI: 10.22146/jmpf.42927

Abstract

Patients with diabetes mellitus (DM) are patients with a low level of treatment adherence. Low adherence is often the cause of treatment failure, so the risk of complications is higher and can affect the quality of life of patients. This study aimed to determine the relationship between treatment adherence to clinical outcomes and the quality of life of patients with type 2 DM. This study used a cross sectional design involving patients with type 2 DM who met the inclusion and exclusion criteria in three health centers in Bantul, Yogyakarta. Data on patient medication compliance was obtained using medication adherence report scale questionnaire (MARS-5), patient quality of life data using Short-Form 6 Dimensions questionnaire (SF-6D), data on fasting blood glucose levels (GDS / GDP) from medical records, socio demographic data obtained from respondents and medical records. The relationship between the level of adherence to clinical outcomes using Chi-square analysis while the relationship between the level of adherence to quality of life using Spearman Rho analysis. The total number of respondents involved was 179 patients, the majority had a low level of adherence (57%), clinical outcomes that had not been achieved (68.7%), and the average utility score was high (0.816). There was a relationship between medication adherence to clinical outcomes (P = 0.002; OR = 2.875). Similarly, between adherence to quality of life, there is a significant relationship (P = 0.006) with a weak correlation level (r = 0.204). Therefore, patients and Health professionals, especially pharmacists, need to pay attention to medication adherence to achieve optimal clinical outcomes and a better quality of life.
The Effect of Variations in HPMC and Carbopol Bases on The Physical Stability of Okra (Abelmoschus esculentus L.) Fruit Gel Formulations Irman Idrus; Rahayu Apriyanti; Syaiful Katadi; Nurfitriyana Rahmat; Sabda Wahab; Dzul Asfi
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 1 (2023): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i1.3399

Abstract

Okra fruit (Abelmoschus esculentus L.) is a vegetable that is often used as medicine. Okra fruit contains flavonoids which are antioxidants. Gel formulation with a concentration of 5%, and various combinations of HPMC and carbopol bases. This research aims to determine the physical stability of gel preparations and the effect of variations in the concentration of gelling ingredients in the preparations. The gel formulation consists of 4 formulas, namely F0, F1, F2, and F3. Physical stability tests include organoleptic tests (odor, color and texture), homogeneity, pH, spreadability, stickiness, viscosity and synergy. Tests were carried out for 14 days of storage, namely on days 1, 3, 5, 7, and 14 at room temperature (25℃). The observation results showed that in the organoleptic test there was no change in color, odor and texture in the gel preparation during 14 days of storage. The four gel formulas are homogeneous and there is no synergy. Variations in the combination of HPMC and carbopol bases affect the physical properties of the gel, including pH, viscosity, spreadability and adhesion. HPMC and Carbopol affect the pH of the preparation, the higher the Carbopol content and the lower the HPMC content, the more acidic it is. Carbopol and HPMC affect the values of spreadability, viscosity and adhesion because the higher the concentration of carbopol and HPMC produces a thick gel preparation so that the spreadability decreases, viscosity increases and adhesion also increases.
EDUKASI PEMANFAATAN POTENSI BAHAN ALAM LOKAL SEBAGAI UPAYA PENCEGAHAN STUNTING PADA MASYARAKAT Salam, Muhamad Ramadhan; Rahmat, Nurfitriyana; Katadi, Syaiful; Apriyanti, Rahayu; Idrus, Irman; Pemudi, Yusniati Dwi
GEMAKES: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2024): GEMAKES: Jurnal Pengabdian Kepada Masyarakat
Publisher : Politeknik Kesehatan Kemenkes RI Jakarta I

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36082/gemakes.v4i1.1467

Abstract

Stunting merupakan kelainan dimana tumbuh kembang balita terhambat akibat kekurangan gizi selama di dalam kandungan dan kondisi ini dapat diketahui dengan melihat kondisi tubuh anak yang lebih kecil dari anak lain seusianya. Pada tahun 2022 prevalensi stunting di Indonesia menurun 21,6% dibandingkan tahun 2021 sebesar 24,4%. Untuk Kabupaten Konawe sendiri tidak mengalami penurunan angka kejadian stunting dimana prevalensi tahun 2021 adalah sebesar 26,3% dan meningkat pada tahun 2022 sebesar 28,3%. Hal tersebut membuktikan bahwa masing kurangnya pengetahuan orang tua dalam memahami kebutuhan gizi anak semenjak anak masih didalam kandungan sampai dengan umur 2 tahun karena pengetahuan yang baik orang tua terhadap kebutuhan gizi dapat menjauhkan anak dari gangguan kesehatan kronis. Kegiatan dimulai dari analisis situasi wilayah kegiatan yaitu Desa Waworaha, Kecamatan Soropia, Kabupaten Konawe, Sulawesi Tenggara; pengurusan perijinan kegiatan kepada aparat desa setempat; pengembangan media edukasi; sosialisasi dan edukasi dalam bentuk pemaparan power point, pengisian kuesioner; analisis deskriptif dengan bantuan software IBM SPSS Statistics 26. Berdasarkan hasil kegiatan dan evaluasi yang telah dilakukan, pengetahuan masyarakat akan stunting dan pemanfaatan tanaman local sebagai Upaya pencegahan stunting masih kurang. Setelah dilakukan edukasi terhadap peserta kegiatan, pengetahuan masyarakat meningkat menjadi 88,54%. Perlu dilakukan sosialisasi kembali oleh pemerintah setempat dan tenaga Kesehatan terkait mengenai stunting dan intervensi spesifik untuk menurunkan angka kejadian stunting.
Kajian Praklinis Ekstrak Etanol Herba Tridax procumbens (Linn.) sebagai Antidiabetik pada Tikus Putih Diabetes (Rattus norvegicus) yang Diinduksi Streptozotosin: Preclinical Study of Ethanol Extract of Herba Tridax procumbens (Linn.) as Antidiabetic in Streptozotocin-Induced Diabetic White Rats (Rattus norvegicus) Syaiful Katadi; Irman Idrus; Arman Rusman; Sitti Sarfila
Jurnal Sains dan Kesehatan Vol. 5 No. 1 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i1.1597

Abstract

This study aims to conduct a preclinical study of the antidiabetic effect of the ethanol extract of the herb Tridax procumbens (Asteraceae) in streptozotocin-induced diabetic rats. The research procedure began by collecting test samples of the Tridax procumbens Linn (TP) herb. All parts of the TP plant which were air-dried were extracted with ethanol (95%) by maceration for 72 hours, then phytochemical screening was carried out to determine the content of secondary metabolites in general. The antidiabetic test was initiated by inducing male Wistar rats with streptozotocin (50 mg/jk, i.p.) and nicotinamide (120 mg/kg, i.p.) by injection. Diabetic rats were treated with glibenclamide (0.25 mg/kg, po) and TP extract (250 and 500 mg/kg, p.o.) for 21 consecutive days. Blood samples were collected periodically to measure the hypoglycemic effect of the TP extract. Then, variations in body weight at the fair were monitored for all experimental animals. The results showed that TP extract had a significant antidiabetic effect on diabetic white rats (Rattus norvegicus), with the best results given TP extract at a dose of 500 mg/kg. Keywords: Tridax procumbens, diabetes mellitus, antidiabetic Abstrak Penelitian ini bertujuan untuk melakukan kajian praklinis efek antidiabetes dari ekstrak etanol herba Tridax procumbens (Asteraceae) pada tikus diabetes yang diinduksi streptozotocin. Prosedur penelitian dimulai dengan mengumpulkan sampel uji herba Tridax procumbens Linn (TP). Seluruh bagian tanaman TP yang telah dikeringkan diekstraksi dengan etanol (95%) dengan cara dimaserasi selama 72 jam, selanjutnya dilakukan skrining fitokimia untuk mengetahui kandungan metabolit sekundernya secara umum. Untuk Uji antidiabetes dimulai dengan menginduksi tikus Wistar jantan dengan streptozotocin (50 mg/kg, ip) dan nicotinamide (120 mg/kg, ip). Tikus diabetes diobati dengan glibenklamid (0,25 mg/kg, po) dan ekstrak TP (250 dan 500 mg/kg, p.o.) selama 21 hari berturut-turut. Sampel darah dikumpulkan secara berkala untuk mengukur efek hipoglikemik ektrak TP. Kemudian, variasi berat badan mingguan dipantau untuk semua hewan percobaan. Hasil penelitian menunjukkan ekstrak TP memiliki efek antidiabetik yang signifikan terhadap tikus putih diabetes (Rattus norvegicus), dengan hasil terbaik pada pemberian ekstrak TP dosis 500 mg/KgBB. Kata Kunci: Tridax procumbens, diabetes mellitus, antidiabetik
Edukasi Budaya Jamu: Memperkuat Kesehatan Masyarakat Dengan Pendekatan Alternatif Muhamad Ramadhan Salam; Nurfitriyana Rahmat; Syaiful Katadi; Rahayu Aprianti; Irman Idrus; Ira Nurmala
ABDI: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 6 No 3 (2024): Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Labor Jurusan Sosiologi, Fakultas Ilmu Sosial, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/abdi.v6i3.869

Abstract

Pengobatan tradisional adalah bagian dari sistem budaya masyarakat yang dapat sangat membantu pembangunan kesehatan masyarakat. Akan tetapi, akan ada masalah dengan penggunaan jamu karena semakin banyak orang yang menggunakannya tanpa mengetahui cara menggunakannya dengan benar untuk memastikan manfaat dan keamanannya. Kegiatan ini bertujuan untuk meningkatkan pengetahuan masyarakat desa Waworaha, Soropia, Konawe, Sulawesi Tenggara tentang penggunaan jamu yang baik dan benar untuk meningkatkan derajat Kesehatan masyarakat. Proses dimulai dengan menilai situasi wilayah, pengurusan izin kegiatan, perancangan media edukasi, sosialisasi dan edukasi, evaluasi kegiatan dengan pengisian kuesioner pengetahuan pre test dan post test, dan selanjutnya analisis karakteristik dan data pengetahuan dengan bantuan Microsoft Excel. Tingkat pengetahuan peserta kegiatan tentang penggunaan tanaman tradisional sebagai bahan utama jamu cukup baik, dengan rata-rata 83,01%. Ada beberapa indikator yang masih kurang dipahami oleh masyarakat, terutama cara penggunaan, cara pengolahan, dan proses seleksi tanaman. Namun, pengetahuan rata-rata meningkat sebesar 91,60% setelah edukasi dan sosialisasi.
Pembuatan Stik Daun Kelor (Moringa oleifera) sebagai Upaya Peningkatan Gizi Jajanan Lokal Idrus, Irman; Katadi, Syaiful; Rahmat, Nurfitriyana; Salam, Muh. Ramadhan; Aprianti, Rahayu; Suriyani, Lilis; Kalsum, Ummi; Trisilia, Wiwin; Fausiyah, Afifah; Ningsih, Sri Yulia; Damayan, Elsa ti
JURNAL LENTERA ILMIAH PENGABDIAN MASYARAKAT Vol. 1 No. 1 (2024): JLIPM - AGUSTUS
Publisher : CV. Q2 Lantera Ilmiah Institut

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Moringa oleifera leaves are known for their high nutritional content, yet their utilization remains limited. This study aimed to develop Moringa leaf-based sticks and evaluate their acceptance. An experimental method was employed, creating three stick formulations: control, 10% Moringa leaf powder (A), and 20% Moringa leaf powder (B). Proximate analysis, organoleptic tests, and community acceptance surveys were conducted. Results showed significant protein, vitamin A, and iron increases in Moringa-fortified sticks. Formulation A had the best acceptance with an average score of 4.2 out of 5 for all organoleptic parameters. Despite higher nutritional value, Formulation B was less preferred due to stronger color intensity and aroma. The survey revealed that 85% of respondents were interested in consuming Moringa sticks regularly. Education and demonstration of stick-making to the community increased interest, with 78% of respondents willing to try making them at home. In conclusion, Moringa leaf sticks have the potential to become a healthy snack alternative that can improve community nutritional intake. Further research on nutrient stability during storage and formulation optimization is needed for better acceptance..