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All Journal Indonesian Journal of Global Health research Indonesian Journal of Global Health Research
Rosmayanti Syafriani Siregar
Universitas Sumatera Utara
Education Health Professions Languange, Linguistic, Communication & Media Nursing Public Health

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Accuracy of Hemoglobin Measurement using the SD Biosensor Standard G6PD Analyzer as Point-of-Care in Pediatric Populations in Malaria-Endemic Regions Kevin Effendi; Rosmayanti Syafriani Siregar; Hendri Wijaya; Olga Rasiyanti Siregar; Arlinda Sari Wahyuni; Ayodhia Pitaloka Pasaribu
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6918

Abstract

Background: Malaria remains a significant public health concern, particularly in endemic regions, is frequently associated with anemia in children. Accurate hemoglobin measurement is crucial for diagnosing anemia, especially in resource-limited settings. This study compares the accuracy of SD Biosensor Standard G6PD Analyzer with Hemocue HB301 System for hemoglobin measurement among children in malaria-endemic areas. Objective: To determine the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR+), negative likelihood ratio (LR-), pretest odds, post-test odds, and overall accuracy of the SD Biosensor Standard G6PD Analyzer compared to the Hemocue HB301 System. Method: This cross-sectional diagnostic study involved 325 children aged 6-18 years in Kualuh Leidong District. Secondary data were obtained from a previous study conducted in August 2024, using a total sampling technique. Result: The mean hemoglobin level measured by SD Biosensor Standard G6PD Analyzer (14,22±2,21 mg/dL) was higher than that measured by Hemocue HB301 System (13,45±1,63 mg/dL), with significant difference (p=0,001). The prevalence of anemia detected by SD Biosensor and Hemocue was 12,3% and 11,4%, respectively. The SD Biosensor Standard G6PD Analyzer demonstrated a sensitivity of 70,27%, specificity of 95,14%, PPV of 65%, NPV of 96,14% and an overall accuracy of 92,31%. Conclusion: The SD Biosensor Standard G6PD Analyzer exhibited relatively low sensitivity but high specificity compared to Hemocue HB301 System in measuring hemoglobin levels among children in malaria-endemic areas. Further research is needed to compare both devices against the gold-standard automated hematology analyzer and to identify the factors influencing measurement accuracy. Keywords: Anemia, Hemocue HB301 System, Hemoglobin, Malaria, SD Biosensor Standard G6PD Analyzer
Factors Associated with Ocular Disorders in Children with Systemic Lupus Erythematosus (SLE) Ivana Garcia Sembiring; Mahrani Lubis; Rosmayanti Syafriani Siregar; Rina Amelia; Rita Evalina; Aridamuriany D. Lubis
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.1198

Abstract

Systemic lupus erythematosus (SLE) is a chronic inflammatory disease involving multiple organs and causing systemic damage, characterized by the formation of autoantibodies and immune complexes. Ocular involvement is estimated to occur in approximately one-third of individuals with SLE and may affect various ocular structures. Ocular manifestations associated with SLE are highly variable and may lead to delayed diagnosis, potentially resulting in poor outcomes and vision-threatening complications. To analyze risk factors associated with ocular disorders in children with systemic lupus erythematosus (SLE). This was an analytic cross-sectional study conducted at the Allergy-Immunology outpatient clinic and pediatric inpatient ward of Adam Malik General Hospital starting in April 2025. The sampling technique used was consecutive sampling. A total of 41 patients with SLE were analyzed. The duration of treatment was found to be a risk factor associated with ocular disorders in children with SLE (p=0.005). The prevalence of ocular disorders among children with SLE was 29.3%. The most common ocular disorder observed in children with SLE undergoing treatment was ocular hypertension, found in 9 patients (22%). Based on ordinal regression analysis, each additional year of treatment duration increased the likelihood of worsening therapeutic outcomes by 1.76 times (p<0.05). Treatment duration is a significant risk factor for ocular disorders in children with systemic lupus erythematosus, with ocular hypertension being the most common type of ocular disorder. Longer treatment duration increases the likelihood of worsening therapeutic outcomes.
Co-Authors Aridamuriany D. Lubis Arlinda Sari Wahyuni Ayodhia Pitaloka Pasaribu Hendri Wijaya Ivana Garcia Sembiring Kevin Effendi Mahrani Lubis Olga Rasiyanti Siregar Rina Amelia Rita Evalina