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Risk of Death in COVID-19 Patients with Comorbidity of Chronic Kidney Disease: Meta Analysis Isna Nur Rohmah; Didik Gunawan Tamtomo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health

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Background: Coronavirus disease 2019 or known as COVID-19 was a disease caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). There are seven comorbidities that experience the most severity and death when infected with COVID-19, namely hypertension, diabetes mellitus, cardiovascular disease, chronic obstructive pulmonary disease, chronic kidney disease, cerebrovascular disease, and cancer. This study aimed to estimate the magnitude of the risk of death in COVID-19 patients with comorbid chronic kidney disease, with a meta-analysis of primary studies conducted by previous authors.Subjects and Method: This study was a systematic review and meta-analysis with the following PICO, population: COVID-19 patients. Intervention: comorbid chronic kidney disease. Compa

The Effectiveness of Ivermectin on the Risk of Mortality in COVID-19 Patients: A Meta Analysis Ayu Trisni Pamilih; Didik Gunawan Tamtomo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 6 No. 4 (2021)
Publisher : Masters Program in Public Health

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Background: The Coronavirus Disease 2019 (COVID-19) has become the highest priority of global pandemic. New and repurposed drugs are being tested on mild to moderate levels of COVID-19 to help suppress transmission of the virus. Ivermectin is one of the repurposed drugs with known safety records with more than 2.5 billion doses dispensed in the past. This study aims to estimate the effectiveness of ivermectin in reducing the risk of mortality in COVID-19 patients based on the results of a number of previous similar studies.Subjects and Method: This study is a systematic review and meta-analysis. This study used secondary data in the form of data from previous study results. A systematic and comprehensive database search was carried out through several databases including: PubMed, Science Direct, Google Scholar, and Springer Link. Analysis of this study was using RevMan 5.3 software. This study used the eligibility criteria with the PICO model, populations: covid-19 patients, intervention: ivermectin administration, comparison: patients without ivermectin, outcome: mortality in COVID-19 patients. The inclusion criteria used were full paper in English and Indonesian with a randomized controlled trial, including the number of deaths, and the primary study was conducted in a hospital. The keywords used to search the database were

Meta-Analysis Correlations between Hypertension, Smoking, and Severity Risk of COVID-19 Lisa Safaah Novia Larsiani; Didik Gunawan Tamtomo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2022.07.03.04

Background: Based on the reported cases, 16.9% of COVID-19 patients were accompanied by comorbidities. Hypertension and smoking are suspected to be one of the pathological determinants that play a role in clinical predictors that are predicted to cause a worsening of the patient's condition during the treatment period. This study aimed to examine correlations between hypertension, smoking, and severity risk of COVID-19.Subjects and Method: Meta-analysis was carried out using PRISMA flow diagrams. Article searches through journal databases include: PubMed, Science Direct, Google Scholar. articles used in 2020-2022. The PICOs in this study were, Population: COVID-19 patients, Intervention: hypertension and smoking Comparation: not hypertension and not smoking, Outcome: severity of COVID-19. The keywords in this study were “hypertention” OR “high blood pressure” AND “severe COVID-19” OR “severty COVID-19” OR “patient COVID-19 outcome” “cigarette” OR “smoking” OR “current smoker” OR former smoker” AND “severe COVID-19” OR “severty COVID-19” OR “patient COVID-19 outcome” Inclusion criteria were articles used in full paper articles with a cohort design, relationship size used with aOR, intervention given the association of hypertension and smoking on the severity of COVID-19. Eligible articles were analyzed using the Revman 5.3 application.Results: A meta-analysis of 12 cohort articles originating from Asia, America, Africa, Europe, concluded that COVID-19 treatment patients with hypertension had higher severity 1.82 times compared to those without hypertension (aOR= 1.82; 95% CI= 1.18 to 2.79; p=0.006). Likewise, COVID-19 treatment patients with smoking habit had higher severity than those who do not smoke (aOR= 0.62; 95% CI= 0.14 to 2.65; p=0.520).Conclusion: COVID-19 patients with hypertension have an increased risk of severity. COVID-19 patients with smoking lower risk of severity. Keywords: Severe COVID-19, hypertention, cigarette. Correspondence:Lisa Safaah Novia Larsiani. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: nl.lisasafaah@gmail.com Mobile: 089536503803.

Meta-Analysis the Impact of Social Restriction during COVID-19 Pandemic on Blood Glucose Control in Type 1 Diabetes Mellitus Patients Yeocelin Mega Pratiwi; Didik Gunawan Tamtomo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health

Background: The COVID-19 lockdown has an impact on the daily lives of people with type 1 diabetes, including restrictions on physical activity, changes in diet, difficulty contacting health care providers and concerns about drug supplies. The purpose of this study was to analyze the impact of the COVID-19 lockdown on blood sugar control in type 1 diabetes mellitus patients.Subjects and Method: This research is a meta-analysis study using PRISMA flowchart guidelines. The PICO model used is Population= type 1 diabetes mellitus patients. Intervention = COVID-19 lockdown. Comparison = before the COVID-19 lockdown. Outcome = HbA1c. The article search process was carried out between 2019 and 2022 using online databases from PubMed, Springer Link and Google Scholar. The keywords used in the article search were “Quarantine” OR “Quarantines” OR “Stay at Home Orders” OR “Health Lockdowns” OR “Self-Quarantine” OR “Self-Quarantine” AND “Diabetes Mellitus” OR “Diabetes Insipidus” OR “Diabetic” OR “Glucose Intolerance” AND “Glycemic Control” OR “Blood Glucose Control”. The inclusion criteria used in this study were full paper articles with cohort studies, using English or Indonesian, the intervention given was COVID-19 lockdown, and the outcome was blood glucose level (HbA1C) in diabetes mellitus patients.The analysis was performed using RevMan 5.3 software.Results: A total of 11 articles reviewed in the meta-analysis showed that the impact of the COVID-19 lockdown decreased HbA1c levels by 0.23 compared to before the COVID-19 lockdown in patients with type 1 diabetes mellitus and was statistically significant (SMD= -0.23; 95% CI -0.29 to -0.18; p<0.001).Conclusion: COVID-19 lockdown reduces HbA1c levels compared to before COVID-19 lockdown in type 1 diabetes mellitus patients. Keywords: COVID-19 lockdown, type 1 diabetes mellitus, HbA1c. Correspondence:Yeocelin Mega Pratiwi. Masters Program in Public Health, Universitas Sebelas Maret. Jalan Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: yeocelinmega@gmail.com. Mobile: 082137652605.

Effect of Diabetes Mellitus Comorbidity on Mortality Risk in Tuberculosis Patients who Received Tuberculosis Treatment: A Meta-Analysis Hakim Anasulfalah; Didik Gunawan Tamtomo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health

Background: Tuberculosis or TB is a disease caused by the Mycobacterium tuberculosis complex. There are several comorbidities that experience severity and death when infected with tuberculosis or TB, namely hypertension, diabetes mellitus, cardiovascular disease, chronic kidney disease, cerebrovascular disease, and other diseases. This study aims to estimate the magnitude of the risk of death in Tuberculosis patients undergoing treatment with comorbid Diabetes Mellitus, with a meta-analysis of primary studies conducted by previous authors.Subjects and Method: This was a systematic review and meta-analysis with the following PICO, population: Tuberculosis patients. Intervention: comorbidities of chronic diabetes mellitus. Comparison: without comorbid diabetes mellitus. Outcome: death. The articles used in this study were obtained from three databases, namely Google Scholar, Pubmed, and Science Direct. Keywords to search for articles “Tuberclosis” OR TBC AND “Diabetes Mellitus” OR DM AND Mortality OR Death The included full-text articles are in English with a cohort study design from 2007 to 2021 and report the adjusted Odds Ratio (aOR) in a multivariate analysis. Article selection is done by using PRISMA flow diagram. Articles were analyzed using the Review Manager 5.3 application.Results: A total of 12 cohort studies involving tuberculosis patients undergoing treatment from America, Europe, Africa and Asia were selected for a systematic review and meta-analysis. The data collected showed tuberculosis patients undergoing treatment with comorbid Diabetes Mellitus had a 1.68 times risk of death compared to COVID-19 patients without comorbid chronic kidney disease (aOR = 1.68; 95% CI = 1.42 to 1.99; p<0.001).Conclusion: Diabetes mellitus comorbidity increases the risk of death in tuberculosis patients undergoing treatment. Keywords: Diabetes Melitus, Tuberculosis, mortality Correspondence:Hakim Anasulfalah. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah. Email: isnanr28@gmail.com. Mobile: 081327215685.

Effectiveness of COVID-19 Vaccine on Augmenting Antibody Level in People in the Special Region of Yogyakarta, Indonesia Joko Budiyono; Bhisma Murti; Didik Gunawan Tamtomo
Journal of Epidemiology and Public Health Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.01.04

Background: Immunity against SARS-CoV-2 is needed to prevent infection so vaccines are indeed humanity's great hope as a weapon to control COVID-19. Seroprevalence data is needed using an antibody test that estimates the percentage of DIY residents who have antibodies against SARS-CoV-2. This study aimed to determine the effectiveness of COVID-19 vaccination on enhancing antibody titers.Subjects and Method: This was a retrospective cohort study conducted in Yogyakarta, Indonesia, from 19 to 30 November 2021. The study population was people aged ≥1 year. A total of 563 study subjects was selected randomly. The dependent variable was the SARS-CoV-2 antibody titer level. The independent variables were COVID-19 vaccination status, gender, age, smoking, outdoor activities, and alcohol consumption. SARS-CoV-2 antibody level was measured using Roche's Elecsys anti-SARS-CoV-2. Other variables were collected using questionnaires. Data were analyzed using a multiple linear regression run on STATA 14.Results: The initial vaccination led to an elevation in -19 antibody titers, but it was statistically non-significant (b= 697.82; 95% CI= -720.90 to 1241.24; p= 0.603). The second vaccination resulted in a notable and statistically significant elevation of COVID-19 antibody titers (b= 1331.38; 95% CI= 802.30 to 1860.46; p <0.001).Conclusion: The second dose of the COVID-19 vaccination demonstrated significant effectiveness in boosting COVID-19 antibody titers. Keywords: COVID-19, vaccination, antibody

Effect of Tertiary Preventive Behavior on HbA1c Level, Quality of Life, and Complication Risk in Diabetes Mellitus Patients Wardhatul Livia; Bhisma Murti; Didik Gunawan Tamtomo; Hanung Prasetya
Journal of Epidemiology and Public Health Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.01.10

Background: Type 2 diabetes mellitus (DM) is a non-communicable disease which is a source of additional severity for other diseases. This study aims to determine the effect of tertiary preventive behavior on hba1c level, quality of life (QoL), and complication risk in diabetes mellitus patients.Subjects and Method: This was a cross-sectional study conducted in Sukoharjo, Central Java, Indonesia, from October to November 2023. A total sample of 200 patients with type 2 diabetes mellitus (DM), registered in the Prolanis program, was selected through multistage random sampling. The independent variables were HbA1c levels, risk of complications, and QoL. The inde-pendent variable was tertiary preventive behavior. HbA1c levels were measured using spectrophotometer. QoL was measured using the WHOQOL questionnaire, and risk of complications using a questionnaire. Data were analyzed using the SEM model.Results: Tertiary prevention behavior significantly increased HbA1c level (b= 0.31; CI 95%= -0.45 to 0.15; p<0.001) and quality of life (b= 0.15; 95% CI= -0.15 to 0.38; p<0.001). Tertiary prevention behavior significantly reduced the risk of complications (b= -0.22; CI 95%= -0.42 to 0.02; p= 0.026). The goodness-of-fit values suggest that the structural equation model (SEM) is acceptable (p= 0.188; RMSEA=0.04; CFI=0.97, TLI=0.95; SRMR=0.05; CD= 0.07).Conclusion: Tertiary prevention behavior significantly increased HbA1c level and quality of life. Tertiary prevention behavior reduces the risk of complications in type 2 DM patients. Keywords: Diabetes mellitus, HbA1c, complications, quality of life

Management of Dual Health Asset Applications Developed by The Ministry of Internal Affairs and Ministry of Health in Hospitals in Boyolali, Central Java, Indonesia Yunita Rusdiyanti; Didik Gunawan Tamtomo; Bhisma Murti
Journal of Health Policy and Management Vol. 5 No. 3 (2020)
Publisher : Masters Program in Public Health, Sebelas Maret University

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Background: The management of health assets in Hospitals is a complex matter. State-onwed Hospitals use two applications from the Ministry of Internal Affairs developed by the Development Audit Agencynamely Regional Management Information System of Regional Assets (Simda BMD) and the Ministry of Health namely Application of Infrastructure and Medical Devices (ASPAK). This study aims to determine the management of health assets based on the applications of the Ministry of Internal Affairs and the Ministry of Health in three Regional Public Hospitals in Boyolali Regency.Subjects and Method: This was a descriptive-qualitative study using a study case approach. This study was carried out in three Regional Public Hospitals in Boyolali Regency. The main informants were goods treasurer, warehouse section, staff in charge of planning and reporting section, staff in charge of ASPAK, head of medical support, and head of administrative subdivision. The data were collected using in-depth interviews, non-participative observation, and document observation. The data were analyzed using three main steps namely data reduction, data display, and conclusion drawing.Results: The staff in charge of asset management in RSUD Boyolali had a sufficient proficiency in the asset concept and management by using the two applications. However, not all steps were conducted on time andfollowing the guidance.Conclusion: The training is required to improve the capability of the staff in charge of asset management. A system is also required to link the two applications to provide more efficient input system and create inter operability.Keywords: asset managementCorrespondence: Yunita Rusdiyanti. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: y_rusdiyanti@yahoo.com. Mobile: 081-22981365.Journal of Health Policy and Management (2020), 05(03): 189-196https://doi.org/10.26911/thejhpm.2020.05.03.04.

Path Analysis on Factors Affecting the Use of Hemodialysis in Patients Chronic Renal Disease at Dr. Soehadi Prijonegoro Hospital Sragen, Central Java Anisa Andriani; Didik Gunawan Tamtomo; Bhisma Murti
Journal of Health Policy and Management Vol. 6 No. 1 (2021)
Publisher : Masters Program in Public Health, Sebelas Maret University

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Background: Patient adherence can be influenced by several factors that can affect compliance with hemodialysis treatment. Adherence is highly treated while undergoing hemodialysis in order to achieve success in hemodialysis (HD) treatment. Adherence is one of the behaviors of a person in achieving successful HD treatment. The success of a treatment can be influenced by several factors, one of which is the use of HD. This study aimed to determine the effect of compliance with hemodialysis.Subjects and Method: The was an observational analytic study with a cross-sectional design. The study was conducted in January 2020. The sample used was 120 chronic kidney failure patients undergoing hemodialysis at Dr. Soehadi Prijonegoro Sragen Hospital. The dependent variable was compliance with hemodialysis. The independent variables are: knowledge, length of care, family income. Data were collected by means of a questionnaire. Data analysis was performed using path analysis with Stata 13.Results: The use of HD in patients with chronic renal failure had a positive association with high HD knowledge (b= 1.22; 95% CI= 2.21 to -3.98; p= 0.027), length of stay (b= 2.09; 95% CI= 4.29 to 3.05; p<0.001), and has no positive relationship with family income (b = 0.40; 95% CI = 0.80 to 1.41; p = 0.426). The use of HD in patients with chronic renal failure is influenced indirectly by family income and length of treatment.Conclusion: The use of HD in chronic renal failure patients has a direct relationship with knowledge of HD and length of treatment, and has no direct relationship with family income. The use of HD in patients with chronic renal failure is influenced indirectly by family income and length of treatment.Keywords: hemodialysis, chronic renal failureCorrespondence: Anisa Andriani. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: andrianianisa390@gmail,com. Mobile: +6282220826660.Journal of Health Policy and Management (2021), 06(01): 13-20https://doi.org/10.26911/thejhpm.2021.06.01.02

Does the Integrated Health Post have Contextual Effect on Tertiary Preventive Behavior among Hypertensive Patients? A Multilevel Analysis Evidence from Surakarta Angga Ferdianto; Didik Gunawan Tamtomo; Endang Sutisna Sulaeman
Journal of Health Promotion and Behavior Vol. 4 No. 3 (2019)
Publisher : Masters Program in Public Health, Sebelas Maret University

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Background: The Indonesian Ministry of Health has launched a community-based non-communicable disease (PTM) control program through the non-communicable disease Integrated Development Post (Posbindu PTM). One of the non-communicable disease which is a very serious health problem is hypertension which is called the silent killer. The purpose of this study was to analyze the contextual effect of integrated development posts on the tertiary prevention behavior of patients with hypertension using Theory of Planned Behavior.Subjects and Method: A cross sectional study was conducted at 25 integrated health post in Surakarta, from September to October 2019. A sample of 200 hipertensive patients was selected by stratified random sampling. The dependent variable was tertiary prevention behavior. The independent variables were education, attitude, subjective norm, perceived behavior control, intention, cadre support, and peer support. The data were collected by questionnaire and analyzed by multiple logistic regression run on Stata 13.Results: Tertiary prevention behavior in patients with hypertention increased with education level ≥Senior high school (b= 1.22; 95% CI= 0.37 to 2.08; p= 0.005), positive attitude (b= 1.51; 95% CI= 0.54 to 2.48; p= 0.002), supportive subjective norm (b= 1.38; 95% CI= 0.46 to 2.29; p= 0.003), strong perceived behavioral control (b= 1.10; 95% CI= 0.17 to 2.03; p= 0.020), strong intention (b= 0.97; 95% CI= 0.13 to 1.82; p= 0.023), strong integrated development post cadre support (b= 1.57; 95% CI= 0.69 to 2.46; p<0.001), and strong peer support (b= 1.46; CI 95% = 0.57 to 2.35; p = 0.001). Integrated development post had a contextual effect on tertiary prevention behavior of hypertension with intra-class correlation (ICC)= 16.03%Conclusion: Education, attitude, subjective norm, perceived behavior control, intention, cadre support, and peer support increased tertiary prevention behavior of hypertension.Keywords: Tertiary prevention of hypertension, Theory of Planned BehaviorCorrespondence: Angga Ferdianto, Institute of Health Science Ngudia Husada Madura, Jl. RE. Martadinata No. 45 Mlajah, Bangkalan 69116. East Java, Indonesia. Email: angga.rmd@gmail.com. Mobile: +6285746555354Journal of Health Promotion and Behavior (2019), 4(3): 224-234https://doi.org/10.26911/thejhpb.2019.04.03.07

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