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Journal : Multidisciplinary Indonesian Center Journal

CORRELATION BETWEEN DENGUE ANTIBODIES IGM AND IGG WITH LYMPHOCYTE COUNT IN PATIENTS WITH SUSPECTED DENGUE FEVER Priyandari, Damar Ajeng; Yanti, Ni Luh Gede Puspita; Muliawati, Ni Kadek
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 4 (2025): Vol. 2 No. 4 Edisi Oktober 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i4.1248

Abstract

Dengue Hemorrhagic Fever (DHF) is a disease caused by the Dengue virus transmitted to humans through the bite of the Aedes aegypti and Aedes albocpitus mosquitoes. One of the laboratory tests that can help diagnose Dengue fever includes Dengue IgM and IgG Antigens and hematology tests. The number of lymphocytes plays a role in the body's immune system and is one of the parameters found in hematology tests. This study aims to determine the relationship between Dengue IgM and IgG antibodies and the number of lymphocytes in patients suspected of having Dengue fever at the Prodia Sunter Clinical Laboratory for the period 2021-2024. The research method is observational with cross-sectional using secondary data of 104 samples. Data analysis uses Spearman rank. The results of the study showed that most of the suspected Dengue fever patients were male, 56 patients (53.8%) with the highest age at 19-59 years as many as 53 patients (51.0%) and the duration of fever was mostly experienced on the 3rd day of fever 29 patients (27.9%). The results of the Dengue antigen IgM examination in suspected Dengue fever patients were negative for 89 patients (85.6%) and the Dengue antigen IgG was negative for 64 patients (61.5%). The number of lymphocytes was within normal limits for 44 patients (42.3%). The results of the IgM correlation test obtained p = 0.005 with r 0.271, so the hypothesis was accepted, it can be concluded that there is a weak correlation between Dengue IgM antibodies and the number of lymphocytes and the results of the IgG correlation test obtained p = 0.043 with r 0.198, so the hypothesis was accepted, it can be concluded that there is a weak correlation between Dengue IgG antibodies and the number of lymphocytes in suspected Dengue fever patients.
THE EFFECT OF GIVING GREEN BETEL LEAF EXTRACT ON THE GROWTH OF Bacteroides IN VAGINAL SECRET CULTURE Nuraini, Deswinda Fadhilah; Yanti, Ni Luh Gede Puspita; Parwati, Putu Ayu; Prihatiningsih, Diah
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 4 (2025): Vol. 2 No. 4 Edisi Oktober 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i4.1277

Abstract

Green betel leaves contain compounds that can treat vaginal discharge, especially those caused by bacteria. To determine the effect of green betel leaf extract on the growth of Bacteroides in vaginal secretion cultures, this study used a quantitative experimental method, where vaginal secretion samples were taken from the subjects and then tested quantitatively. There were two data collection techniques used in this study: using a questionnaire and testing vaginal secretion samples with green betel leaf extract. The test for using was diffusion (paper disc) for the antibacterial test. The media used was MHA. The positive control used was a blank disc, the extract concentration series used were 20%, 25% and 30%. The diameter of the inhibition zone was observed and then analyzed. The results of the t-test analysis showed that the significance value was 0.00 <0.05, so H0 was rejected Ha was accepted or it could be concluded that there was a difference in the effect of giving green betel leaf extract on the growth of Bacteroides in vaginal secretion culture. Antibacterial activity test of green betel leaves (Piper betle L) against Bacteroides bacteria that cause Bacterial Vaginosis, namely resistant at a concentration of 20%, intermediate at a concentration of 25% and sensitive at a concentration of 30%. Green betel leaf extract (Piper betle L) has inhibitory power against Bacteroides bacteria that cause Bacterial Vaginosis. Can increase the concentration series of methanol extract of green betel leaves, find the minimum bactericidal concentration (MBC) and the maximum inhibitory concentration (MIC) of green betel leaf extract against Bacteroides bacteria that cause Bacterial Vaginosis
COMPARISON OF FRESH SERUM TOTAL CHOLESTEROL RESULTS WITH THOSE OF SERUM STORED AT ROOM TEMPERATURE FOR 6 HOURS AT JATI PADANG GENERAL HOSPITAL Sari, Anis Sinta; Yanti, Ni Ketut Ayu Mira; Yanti, Ni Luh Gede Puspita
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 4 (2025): Vol. 2 No. 4 Edisi Oktober 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i4.1282

Abstract

Exposure to X-ray radiation in conventional radiology procedures can pose a health risk, especially for accompanying caregivers of pediatric patients who only bear the risk without gaining any benefit. This study aims to determine the estimated equivalent dose received by accompanying caregivers of pediatric patients and the safest points during conventional radiology examinations. The method used in this research is a field survey, involving the measurement of equivalent radiation doses inside and outside the examination room using a personal dosimeter, as well as measuring the radiation dose rate at 6 points using a surveymeter. The data was processed to obtain the highest and lowest values, as well as the percentage of equivalent dose obtained compared to the established Dose Limit Value (DLV). The results showed that the highest radiation dose received by accompanying caregivers inside the examination room reached 13,46 µSv, with a percentage of 0,27% relative to the DLV, while the lowest dose recorded was 1,12 µSv, with a percentage of 0,0224% relative to the DLV. Analysis of the radiation dose rate distribution revealed that the greater the distance of the measurement point from the radiation source (tube), the smaller the dose received. In conclusion, the radiation dose received by accompanying caregivers is still below the Dose Limit Value (DLV) for caregivers, which is 5.000 µSv. However, to minimize stochastic effects, the implementation of additional protective measures, such as the use of lead aprons and selecting safer locations within the examination room, is highly recommended. These findings are expected to serve as a guide in enhancing the safety of accompanying caregivers of pediatric patients in conventional radiology units.
KORELASI KADAR VITAMIN D DENGAN HEMOGLOBIN PADA IBU HAMIL Purwanti, Ika Setya; Arisandi, Devi Teguh; Yanti, Ni Luh Gede Puspita
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 1 No. 3 (2024): Vol. 1 No. 3 Edisi Juli 2024
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v1i3.135

Abstract

Hampir dua pertiga ibu hamil di Indonesia mengalami anemia atau kurangnya kadar hemoglobin. Kadar vitamin D yang rendah dapat mengakibatkan terjadinya resiko anemia gestastional. Dalam hal mekanisme biologis, Vitamin D mempengaruhi konsentrasi kadar hemoglobin dalam mengatur erythropoetin, sel imun dan produksi hepcidin. Tujuan penelitian ini untuk mengetahui korelasi kadar vitamin D dengan Hemoglobin pada ibu hamil di Prodia Bandung periode tahun 2022. Metode penelitian adalah penelitian kuantitatif dengan design cross sectioanl menggunakan pendekatan purpossive sampling menggunakan data sekunder sebanyak 669 sampel. Hasil penelitian didapatkan kadar Vitamin D terdapat 280 sampel (41,9%) tergolong dalam kategori cukup (sufficiency) dan hasil kadar hemoglobin yang normal yaitu sejumlah 622 ibu hamil (93%). Analisa data statistik dengan Spearman rho menunjukan nilai p value 0,653 > α (0,05). Hal ini berarti Ha ditolak dan H0 diterima yang artinya tidak terdapat hubungan signifikan antara kadar Vitamin D dan Hemoglobin pada ibu hamil. Kadar Hemoglobin pada ibu hamil tidak hanya dipengaruhi oleh kadar Vitamin D tetapi ada faktor lain seperti usia kehamilan, asupan vitamin, asupan makanan, aktivitas fisik dan faktor lainnya.
HUBUNGAN PEMERIKSAAN SARS-COV2 RNA DENGAN D-DIMER PADA PASIEN YANG DIDIAGNOSA COVID-19 DI LABORATORIUM KLINIK PRODIA SUMEDANG Prasetya, Didik; Juariah, Ade; Candrawati, Sang Ayu Ketut; Yanti, Ni Luh Gede Puspita
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 1 No. 3 (2024): Vol. 1 No. 3 Edisi Juli 2024
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v1i3.156

Abstract

Coronavirus Disease 2019 (Covid-19) adalah penyakit menular yang disebabkan oleh virus SARS-CoV2. Selain menyebabkan gangguan pernapasan, virus ini juga menyebabkan hiperkoagulasi yang ditandai dengan peningkatan kadar D-Dimer. Salah satu pemeriksaan laboratorium yang digunakan untuk memastikan apakah seseorang terinfeksi penyakit Covid-19 adalah pemeriksaan SARS-CoV2 RNA. Penelitian ini bertujuan untuk mengetahui hubungan pemeriksaan SARS-CoV2 RNA dengan kadar D-Dimer pada pasien yang didiagnosa Covid-19. Metode yang digunakan dalam penelitian ini adalah analitik observasional dengan pendekatan cross sectional. Jumlah sampel adalah 30 data sekunder pasien yang melakukan pemeriksaan D-Dimer dan SARS-CoV2 RNA atau pun pasien yang melakukan pemeriksaan D-Dimer dengan data rekam medis SARS- CoV2 RNA yang didiagnosa Covid-19 periode Januari 2021 sampai Juli 2022. Hasil penelitian ini didapatkan responden dengan hasil SARS-CoV2 RNA terdeteksi sebanyak 25 (83,3%) dan tidak terdeteksi sebanyak 5 (16,7%). Kadar D-Dimer normal sebanyak 7 (23,3%) dan abnormal 23 (76,7%). Hasil uji Chi Square penelitian ini tidak ada hubungan antara pemeriksaan SARS-CoV2 RNA dengan D- Dimer pada pasien yang didiagnosa Covid-19 dengan nila Asymp. Sig 0,334. Dapat disimpulkan bahwa kadar D-Dimer pada pasien yang didiagnosa Covid-19 dengan hasil SAR-CoV2 RNA terdeteksi tergantung dari tingkat derajat keparahan penyakit.
DIFFERENCE IN URIC ACID TEST RESULTS USING PLAIN AND CLOT ACTIVATOR VACUTAINER TUBES Permana, Anak Agung Gede Denny Dwi; Cahyani, Anak Agung Ayu Eka; Yanti, Ni Luh Gede Puspita
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 4 (2025): Vol. 2 No. 4 Edisi Oktober 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i4.1416

Abstract

Laboratory examinations play an important role in supporting disease diagnosis and treatment, one of which is the measurement of uric acid levels. The accuracy of laboratory results is significantly influenced by the pre-analytical stage, including the type of blood collection tube used. Two commonly used tubes are the plain vacutainer and the clot activator vacutainer, each with different additives that may affect blood clotting time and test results. This study aimed to determine the differences in uric acid test results and clotting time using these two types of tubes. A simple experimental method with a comparative design was conducted at Klinik Pratama Rawat Jalan Mambal Medical Care from March to April 2025. The sample consisted of 15 respondents, each undergoing two blood draws using both tube types. The results showed that the average clotting time for the clot activator tube was 9.27 minutes, while for the plain tube it was 24.67 minutes. The average uric acid level measured using the clot activator tube was 5.27 mg/dL, compared to 5.14 mg/dL using the plain tube. Statistical analysis using the Wilcoxon signed-rank test indicated a significant difference in clotting time but no significant difference in uric acid levels (p > 0.05). It can be concluded that the use of clot activator vacutainer tubes accelerates the blood clotting process but does not significantly affect uric acid levels compared to plain tubes.