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All Journal Jurnal Kedokteran Jurnal Sains Teknologi dan Lingkungan (JSTL) Jurnal Biologi Tropis Jurnal Medika Malahayati ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Medika Hutama Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) PrimA: Jurnal Ilmiah Ilmu Kesehatan Jurnal Pepadu Lombok Medical Journal
Indah Sapta Wardani
Fakultas Kedokteran Universitas Mataram, Lombok, Indonesia
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Bipolar Disorder with Psychosis Featured in Patient with Systemic Lupus Erythematosus Liya Maulidianti; I Putu Diatmika; Indah Sapta Wardani
Jurnal Psikiatri Surabaya Vol. 12 No. 1 (2023): May
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v12i1.34880

Abstract

Abstracts Introductions: Bipolar disorder (BD) is a mental disorder that imposes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks, characterized by biphasic mood episodes of mania or hypomania and depression. More than half of all individuals diagnosed with BD experience psychosis features in their lifetime. The cause of BD is not entirely known, study claims that BD may occur due to or associated with autoimmune diseases. Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with various physical manifestations, including neuropsychiatric features. Case: This case report will discuss a 22-year-old female with BD admitted to the emergency room due to solid psychosis features. The patient was diagnosed with SLE 3 years ago but never controlled prior to the disease history. The psychiatrist’s treatment in the emergency room was an extra injection of haloperidol 5 mg IM and diazepam 10 mg IM, continued with oral medication clozapine 25 mg two times a day and additional therapies such as cognitive behavioral therapy (CBT) and family therapy. The treatment from the internist was symptomatic medication due to the acute SLE symptoms, followed by autoimmune medicines such as steroids and hydroxychloroquine. Conclusions: BD may be associated with SLE. Psychosis features generally occur in BD, usually in the manic period. Treatment should be done for both psychiatric and internal medicine problems. As the SLE symptom was controlled, the BD symptom improved.
Vitamin D: Role in Autoimmune Disease: Vitamin D: Role in Autoimmune Disease Indah Sapta Wardani
JURNAL SAINS TEKNOLOGI & LINGKUNGAN Vol. 9 No. 1 (2023): JURNAL SAINS TEKNOLOGI & LINGKUNGAN
Publisher : LPPM Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jstl.v9i1.441

Abstract

Vitamin D has been associated with regulation on bone metabolism.  Recently, the extra skeletal effect of vitamin D has been researched. Increasing evidence demonstrated strong association between vitamin D and many biological process that regulate immune responses. Vitamin D deficiency is known to be related to the development of the autoimmune diseases. The discovery of the vitamin d receptor in multiple immune cell lineage supports vitamin D with a novel role in modulating immune function and its subsequent role in the development or prevention of autoimmune disease. Vitamin d Deficiency is related to development and severity of reumathoid arthritis (RA), Systemic Lupus Erythematosus (SLE), multiple sclerosis, Type 1 diabetes mellitus and inflammatory bowel disease. Normal level of vitamin D is required for immune function focus on therapeutic and prevention effect in autoimmune disease.
KAJIAN PUSTAKA: MEKANISME KEKURANGAN VITAMIN D DAN PENGARUHNYA PADA PENYAKIT DEGENERATIF Indah Sapta Wardani; Zanetha Mauly Ilawanda
Jurnal Medika Malahayati Vol 7, No 2 (2023): Volume 7 Nomor 2
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v7i2.10426

Abstract

Abstrak: Kajian Pustaka: Mekanisme Kekurangan Vitamin D Dan Pengaruhnya Pada Penyakit Degeneratif. Defisiensi vitamin D merupakan masalah kesehatan masyarakat di seluruh dunia yang sering ditemukan. Di negara dengan pajanan sinar matahari yang cukup, defisiensi vitamin D masih merupakan masalah kesehatan. Banyak faktor yang berkontribusi pada defisiensi vitamin D antara lain paparan sinar matahari dan tidak adekuatnya asupan nutrisi yang mengandung vitamin D. Defisiensi vitamin D dihubungkan dengan berbagai penyakit degeneratif seperti osteoporosis dan fraktur, penyakit kardiovaskular, dan diabetes melitus. Peran suplementasi vitamin D dalam makanan dan pemahaman mengenai pentingnya paparan sinar matahari diperlukan sebagai salah satu strategi untuk pencegahan dan tatalaksana terkait defisiensi vitamin D.
Diabetes Melitus Tipe 2 dengan Hipertiroid dan Hipertensi: Case Report Akelba, Shalsa Damai; Putu Wika Pramesti Iswari; Adam Trojan Alisyahbana; Aulia Dwi Hendriani; Baiq Ramdhani Amelia Negara; Grandis Cristagalli1, Izza Mufida; M. Andre Darmawan; Nadia Safira; Ni Putu Visty Wedhiani; Rike Delya Rizqina; Tri Sastra Pradhini; Indah Sapta Wardani
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2782

Abstract

Diabetes mellitus (DM) is high levels of glucose in the blood (hyperglycemia) accompanied by disturbances in carbohydrate, lipid, protein metabolism as a result of insufficiency of insulin function which can be caused by impaired or deficient insulin production by beta cells in the pancreas or can also be caused by a lack of responsiveness of insulin cells. The prevalence of diabetes mellitus is 9.3% or around 463 million people suffer from diabetes in 2019. One of the risk factors for diabetes mellitus is hyperthyroidism and hypertension. The right treatment for patients suffering from type 2 diabetes mellitus with hyperthyroidism and hypertension is to reduce glucose levels, blood pressure, and reduce the production of the thyroid gland
Literature review: Maturity Onset Diabetes of the Young (MODY) Bramantyo, Rofi; Fauzan, Naufal Revaldy; Wahyudi, Reza Rizwandipa; Dzulilmi, Dhaifatu; Putri, Septy Rianty Salsabilla Dwi; Prameswari, Devi Shanti; Dhevi, Ni Made Shaithanya Gitanjali; Putri, Alifia Sabira; Maudina, Baiq Zaskia; Rizqi, Amanda Suana; Salsabila, Ruhaniah Najwa; Wardani, Indah Sapta
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.8362

Abstract

Maturity Onset Diabetes of the Young (MODY) is a group of monogenic genetic disorders that cause diabetes with an autosomal dominant inheritance pattern, generally appearing before the age of 25. MODY is caused by gene mutations affecting pancreatic beta cell function, with 14 genetic subtypes identified. Diagnosis is often delayed or incorrect, as symptoms resemble type 1 or type 2 diabetes. The diagnosis of MODY is diagnosed through family history, clinical examination, and genetic analysis. MODY treatment is tailored to the genetic subtype, including lifestyle changes, sulfonylureas, and insulin, is tailored to the genetic subtype. Prognosis and risk of complications vary depending on the subtype, with MODY 2 (GCK) having the best prognosis. Prevention includes genetic testing for individuals with a family history of MODY, as well as lifestyle modifications to reduce the risk of complications. Patient education is important to ensure optimal management and prevention of long-term complications. This journal aims to learn more about the following definitions, to prognosis and education of MODY.
The Relationship of Medication Adherence in Type 2 Diabetes Mellitus Patients with HbA1c Profile at Mataram University Hudhori, Syalsa; Wardani, Indah Sapta; Isnaeni, Wilya
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10407

Abstract

Type 2 Diabetes Mellitus (DM) requires optimal glycemic control. Medication adherence is key to achieving HbA1c targets, but local data at Universitas Mataram Hospital is still limited. This study aimed to analyze the relationship between medication adherence and HbA1c profiles in type 2 DM patients. An analytical cross-sectional study was conducted in May 2025 with 40 randomly selected samples. Adherence was measured using the MMAS-8 questionnaire, and HbA1c data came from medical records. Data analysis used the Chi-Square test. Results showed 50% of subjects were adherent and 50% were non-adherent. Regarding glycemic control, 70% had controlled HbA1c. Statistical analysis found no significant relationship between adherence and HbA1c profile (p-value = 0.490). However, a proportional trend showed the adherent group had a higher percentage of HbA1c control (75%) than the non-adherent group (65%). Conclusion, there was no statistically significant relationship between medication adherence and HbA1c profiles. Despite this, the observed clinical trend indicates that adherence remains an important factor to consider in DM management, alongside other determinants like diet and physical activity.
Co-Authors A.A Ayu Niti Wedayani Adam Trojan Alisyahbana Akelba, Shalsa Damai Aliza Raudatin Sahly Aulia Dwi Hendriani Baiq Ramdhani Amelia Negara Bramantyo, Rofi Daffa Muhammad Rizky Decky Aditya Z Devi Rahmadhona Dewi Suryani Dewi Suryani Dhevi, Ni Made Shaithanya Gitanjali Dzulilmi, Dhaifatu Fahmi Akbar Utomo Fauzan, Naufal Revaldy Grandis Cristagalli1, Izza Mufida Herpan Syafii Harahap Hudhori, Syalsa I Dewa Ayu Natih Canis Paloma I Putu Diatmika Ika Nurfiria Tauhida Ilsa Hunaifi Indana Eva Ajmala Isnaeni, Wilya Jurnal Pepadu Karina Khilmi Adzuba Layus Iranna Umayya Lestari, Rizka Vidya Liya Maulidianti M. Andre Darmawan Maudina, Baiq Zaskia Metta Octora Mitha Yunda Pertiwi Mohammad Rizki Mohammad Rizki Muhammad Gasim Al aydrus Nadia Safira Ni Luh Made Mirah Rahayu Ni Luh Putu Harta Wedari Ni Putu Visty Wedhiani Nurhidayati Padauleng, Novrita Prameswari, Devi Shanti Prima Belia Fathana Putri, Alifia Sabira Putri, Septy Rianty Salsabilla Dwi Putu Wika Pramesti Iswari Rike Delya Rizqina Rizqi, Amanda Suana Sahly, Aliza Raudatin Salsabila, Ruhaniah Najwa Tri Sastra Pradhini Wahyudi, Reza Rizwandipa Zanetha Mauly Ilawanda