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Puspitasari, Ratih Dyah
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Journal : CHEMPUBLISH JOURNAL

 1 
Formulation and Characterization of Microencapsules Containing Ethanol Extract of Sungkai Leaves (Peronema canescens Jack) Tarigan, Indra Lasmana; Farah, Farah; Puspitasari, Ratih Dyah; Saharin, Siti Munirah; Latief, Madyawati
Chempublish Journal Vol. 9 No. 1 (2025): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v9i1.43042

Abstract

The Sungkai plant (Peronema canescens Jack) is a widely recognized medicinal plant in Indonesia, with its leaves recently gaining attention for their potential health benefits. This study explores the microencapsulation of ethanol extract from Sungkai leaves using three different coating materials—maltodextrin, inulin, and Arabic gum—at varying concentrations. The aim of this study was to identify the optimal microencapsulation formulation using these materials. Microencapsulation was performed using the extrusion method, and the best formulation was characterized by evaluating its physicochemical properties, morphology, and infrared (IR) spectrum. Antioxidant activity was measured using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The results showed that microencapsulant formulation A1 exhibited superior physicochemical properties compared to other formulations. Scanning electron microscopy (SEM) analysis of sample A1 revealed a smooth surface with a slightly rounded shape and minimal wall folds or cracks, suggesting good stability. Fourier-transform infrared (FTIR) analysis confirmed effective encapsulation of the ethanol extract. While the crude extract demonstrated the highest antioxidant activity, microencapsulation slightly reduced this activity. Among the microencapsulated samples, formulation A1 (using Arabic gum) retained the most antioxidant potential. In conclusion, formulation A1, utilizing Arabic gum as the coating material, was found to be the optimal microencapsulation formulation for the ethanol extract of Sungkai leaves.
Antioxidant Activity of Bioactive Compounds in the Ethyl Acetate Extract of Putat Leaves (Planchonia valida) Nelson; Silaban, Desy Vania; Farid, Faizar; Puspitasari, Ratih Dyah; Tarigan, Indra Lasmana; Ramadhan, Ilham Ifandi; Latief, Madyawati
Chempublish Journal Vol. 6 No. 4 (2022): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v6i4.41632

Abstract

The Putat leaf (Planchonia valida) is a plant traditionally used by the community in the Tanjung Lanjut area, Jambi, both as a salad ingredient and as a traditional medicine to treat skin diseases and promote health. This identifies that the putat plant contains chemical compounds that potentially have antioxidant activity. In this study, putat leaf samples (Planchonia valida) that potentially have antioxidant activity. In this study, Planchonia valida (P. valida) leaf samples using n-hexane and ethyl acetate solvents through a multistep maceration process. Subsequently, phytochemical screening and antioxidant activity tests were conducted to obtain information about fractions that have the potential to be further isolated. The extraction percentage with a yield value of 1,28% was obtained in the maceration process. Further isolation was carried out using isolate liquid chromatography and FT-IR instruments. The obtained isolate was in the form of a wet solid, and through characterization, it was classified as a steroid compound suspected to be ergosterol. Free radicals or oxidants have reactive effects on the human body and can trigger various types of diseases. Antioxidants are known to have the ability to inhibit or neutralize free radicals in the human body. This study tested antioxidant activity using the DPPH (1,1-diphenyl-1,1-picrylhydrazyl) method on isolating F1. Isolate F1 was found to have antioxidant activity with a value of 714.637 ppm, falling into the range of weak antioxidant activity
Co-Authors Allwar Allwar Arnis, Suzi Guci Dewi, Tribuana Tungga Dhian Eka Wijaya Dwiarso Rubiyanto Elis Kartika Endi Adriansyah Faizar Farid Farah, Farah Hariestya Viareco Heriyanti Heriyanti, Heriyanti Indra Lasmana Tarigan Lizawati Lizawati Madyawati Latief Muhaimin Muhaimin Munifilia Ekasari Nelson Nurul Pratiwi Oktariyani, Salmiyah Ramadhan, Iham Ifandi Ramadhan, Ilham Ifandi Restina Bemis, Restina Saharin, Siti Munirah Sarani, Desfira Shella, Ance Pramai Silaban, Desy Vania Sinurat, Julius Alvin Novensius Sowe, Momodou Salieu Susanto, Nindita Clourisa Amaris Sutrisno, Sutrisno Ulvia, Tiara