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KORELASI PEMERIKSAAN IGE TOTAL DENGAN PERSENTASE EOSINOFIL PADA PASIEN TERDIAGNOSA HIPERSENSITIVITAS TIPE 1 : CORRELATION TOTAL IGE LEVELS AND EOSINOPHIL PERCENTAGE IN PATIENTS DIAGNOSED WITH TYPE 1 HYPERSENSITIVITY Fahri, Muhamad; Prihatiningsih, Diah; Sari, Lia Cahya
Medic Nutricia : Jurnal Ilmu Kesehatan Vol. 14 No. 5 (2025): Medic Nutricia : Jurnal Ilmu Kesehatan
Publisher : Cahaya Ilmu Bangsa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hipersensitivitas tipe 1 merupakan reaksi imunologis kompleks yang umumnya ditandai oleh peningkatan kadar Imunoglobulin E (IgE) dan aktivasi eosinofil, namun literatur yang ada menunjukkan inkonsistensi mengenai hubungan linier antara kedua parameter biologis tersebut. Penelitian ini bertujuan untuk mengevaluasi korelasi antara kadar IgE total dengan persentase eosinofil pada populasi pasien yang terdiagnosis hipersensitivitas tipe 1, guna memahami pola respons imun yang terjadi. Studi ini menggunakan desain observasional analitik dengan pendekatan cross-sectional, yang melibatkan 114 pasien yang memenuhi kriteria diagnosis klinis di lokasi penelitian. Berdasarkan hasil analisis statistik menggunakan uji Chi-Square, penelitian ini menemukan bahwa tidak terdapat korelasi yang signifikan antara kadar IgE total dengan persentase eosinofil (p = 0,241). Temuan ini mengindikasikan bahwa meskipun IgE dan eosinofil sama-sama berperan sentral dalam patogenesis alergi, keduanya mungkin merepresentasikan jalur aktivasi imun atau fase peradangan yang berbeda, di mana peningkatan kadar IgE tidak serta-merta disertai dengan eosinofilia perifer. Oleh karena itu, faktor lain seperti variasi individual, aktivasi sel mast, atau mediator inflamasi lainnya perlu dipertimbangkan, dan penegakan diagnosis sebaiknya tidak bergantung pada parameter tunggal melainkan melalui pendekatan multiparameter yang komprehensif. Kata Kunci: Eosinofil, hipersensitivitas tipe 1, IgE total Abstract Type 1 hypersensitivity is a complex immune reaction typically characterized by elevated levels of Immunoglobulin E (IgE) and eosinophil activation; however, existing literature presents inconsistent findings regarding the linear relationship between these two biological markers. This study aimed to evaluate the correlation between total IgE levels and eosinophil percentage in patients diagnosed with type 1 hypersensitivity to elucidate the underlying immune response patterns. Employing an analytical observational design with a cross-sectional approach, this study involved 114 patients who met the specific diagnostic criteria at the study site. Statistical analysis using the Chi-Square test revealed no significant correlation between total IgE levels and eosinophil percentage (p = 0.241). These findings indicate that although both IgE and eosinophils play central roles in allergic pathogenesis, they may represent distinct immune activation pathways or different inflammatory phases, where elevated IgE levels are not necessarily accompanied by peripheral eosinophilia. Consequently, other factors such as individual variability, mast cell activation, or alternative inflammatory mediators should be considered, suggesting that clinical diagnosis requires a comprehensive multiparameter approach rather than reliance on a single biomarker. Keywords: Eosinophils, Total IgE, Type 1 Hypersensitivity
The Influence of Socioeconomic Factors and Religiosity on Religious Tolerance Among Students at Indonesian Islamic Higher Education Institutions Zulkifli, Zulkifli; Latifa, Rena; Fahri, Muhamad; Sa’diyah , Sholikatus
Jurnal Pendidikan Islam Vol 12 No 1 (2026): Jurnal Pendidikan Islam
Publisher : The Faculty of Tarbiyah and Teacher Training associated with PSPII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/jpi.v12i1.48952

Abstract

Religious tolerance is fundamental to establishing religious moderation and harmonious life, a critical issue that has garnered considerable attention from researchers and academics in Indonesia. Understanding tolerance requires considering various factors that shape and influence it beyond simple faith dimensions. This study investigates the influence of specific socioeconomic factors and personal religiosity on the religious tolerance levels among Muslim students attending Indonesia’s State Islamic Higher Educational Institutions (PTKIN). Employing a quantitative approach, the research utilizes multiple regression analysis to examine the relative contributions of the independent variables (socioeconomic factors and religiosity) toward religious tolerance. The findings indicate that three out of four socioeconomic aspects, gender, organizational affiliation, and parental income, significantly affect students’ religious tolerance. Conversely, the amount of allowance received was not found to be a significant predictor of tolerance. Crucially, the students’ self-reported personal religiosity did not significantly influence their religious tolerance scores. This suggests that tolerance among PTKIN students is not explained by their individual depth of religious observance or piety level. The study implies that promoting effective religious tolerance within Islamic educational contexts should prioritize strategies that enhance social and economic exposure, particularly through engaging organizational and diverse university-level social activities, rather than focusing solely on increasing religious instruction.
The Application of Augmented Reality Based Bingo Media in Teaching Arabic Vocabulary to Students at Rahma’ Islamic Junior High School Mutiaturrahma; Susiawati, Wati; Fahri, Muhamad
INTIFA: Journal of Education and Language Vol. 3 No. 1 (2026): INTIFA: Journal of Education and Language
Publisher : Penerbit Minhaj Pustaka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62083/intifa.v3i1.274

Abstract

This study aims to examine the effectiveness of using Bingo media based on Augmented Reality (AR) in teaching Arabic vocabulary to eighth-grade students at Ruhama Islamic Junior High School. The research was motivated by students’ low mastery of vocabulary due to the dominance of traditional, less interactive teaching methods. The study employed a quantitative approach with a quasi-experimental design, involving two groups: an experimental group taught using AR-based Bingo and a control group taught using conventional methods. Data were collected through pre-tests and post-tests and analyzed using normality and homogeneity tests, the Mann–Whitney U test, and the N-Gain formula to measure learning improvement. The findings revealed a statistically significant difference between the two groups, with the experimental group achieving a higher post-test mean score (85.4) compared to the control group (36.1). The N-Gain average reached 81.57%, categorized as high effectiveness. These results demonstrate that AR-based Bingo is highly effective in enhancing students’ vocabulary acquisition, motivation, and active participation, while also promoting a more engaging and meaningful Arabic learning experience.