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Complete Neurological Recovery Following 360-Degree Decompression and Fusion for T11 Giant Cell Tumor: A Case Report Ermawan, Rieva; Bayu Sakti Jiwandono; Denny Firdaus
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 11 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i11.1114

Abstract

Background: Giant cell tumors (GCTs) are benign but locally aggressive bone tumors that rarely affect the spine. The thoracic spine is an even rarer location for GCTs, and their presentation with paraplegia poses a significant challenge. This case report describes the successful surgical management of a T11 GCT-causing paraplegia, highlighting the importance of early diagnosis and aggressive surgical intervention. Case presentation: A 27-year-old female presented with acute paraplegia and a history of chronic lower back pain. Imaging revealed a destructive lesion in the T11 vertebral body with spinal cord compression. The patient underwent a 360-degree decompression, en bloc tumor resection, and posterior spinal fusion. Histopathological analysis confirmed the diagnosis of GCT. The patient experienced complete neurological recovery within five days postoperatively and remained symptom-free at the 5-year follow-up. Conclusion: This case demonstrates the feasibility of achieving complete neurological recovery in patients with T11 GCT and paraplegia through aggressive surgical intervention. Early diagnosis and complete tumor resection followed by spinal stabilization are crucial for optimal outcomes.
Complete Neurological Recovery Following 360-Degree Decompression and Fusion for T11 Giant Cell Tumor: A Case Report Ermawan, Rieva; Bayu Sakti Jiwandono; Denny Firdaus
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 11 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i11.1114

Abstract

Background: Giant cell tumors (GCTs) are benign but locally aggressive bone tumors that rarely affect the spine. The thoracic spine is an even rarer location for GCTs, and their presentation with paraplegia poses a significant challenge. This case report describes the successful surgical management of a T11 GCT-causing paraplegia, highlighting the importance of early diagnosis and aggressive surgical intervention. Case presentation: A 27-year-old female presented with acute paraplegia and a history of chronic lower back pain. Imaging revealed a destructive lesion in the T11 vertebral body with spinal cord compression. The patient underwent a 360-degree decompression, en bloc tumor resection, and posterior spinal fusion. Histopathological analysis confirmed the diagnosis of GCT. The patient experienced complete neurological recovery within five days postoperatively and remained symptom-free at the 5-year follow-up. Conclusion: This case demonstrates the feasibility of achieving complete neurological recovery in patients with T11 GCT and paraplegia through aggressive surgical intervention. Early diagnosis and complete tumor resection followed by spinal stabilization are crucial for optimal outcomes.
Current and Future Global Research Trends in Osteosarcoma: A Bibliometric Analysis of Surgical Strategies and Recurrence Dalimunthe, Ridha Aswina; Saputra, Rhyan Darma; Ermawan, Rieva
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 15 No. 1 (2026): April 2026
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v15i1.2026.56-67

Abstract

Background: Osteosarcoma is the most common primary malignant bone tumor, yet comprehensive mapping of its evolving research landscape remains limited. This bibliometric analysis aims to characterize global research trends, identify thematic hotspots, and delineate emerging directions in osteosarcoma research, with a particular focus on publications related to local control, recurrence, and wide surgical margins.Methods: Publications from January 2021 to April 2025 were retrieved from the Dimensions database using the terms “osteosarcoma,” “local control,” “recurrence,” and "wide margins." After screening, 498 eligible records were analyzed using Bibliometrix/Biblioshiny in RStudio and Microsoft Excel.Results: Publication output increased from 2021 to 2023, with China, the United States, and Japan as the leading contributors. Chinese institutions represented 23% of the top 50 productive organizations, whereas Canada, Austria, and Greece showed the highest international collaboration rates. Thematic mapping identified motor themes related to tumor classification, treatment, prognosis, and local recurrence; niche themes such as en bloc sacrectomy and 3D-printed reconstruction; and emerging themes including artificial intelligence-based risk prediction and early metastasis detection.Conclusions: This bibliometric analysis identifies a trend in osteosarcoma research toward technology -driven and precision-oriented surgical strategies, including AI-assisted risk stratification, 3D-printed reconstruction, and immunomodulatory perioperative approaches. These bibliometric trends suggest growing research interest in optimizing local control and minimizing recurrence, although their clinical impact remains to be validated through prospective studies. The findings provide a descriptive overview of current research directions and may inform future research prioritization.