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Faktor-faktor yang mempengaruhi dismenore primer terhadap kualitas hidup wanita: Tinjauan pustaka Fathiyyah, Nurul; Kwarta, Cityta Putri; Imeldawati, Rakhmalia; Ganisia, Ainun; Kusumawardani, Lentera Afrida
Indonesian Journal of Health Science Vol 4 No 6s (2024): Mewujudkan Indonesia Sehat: Transformasi Sistem Kesehatan di Era Baru
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v4i6s.1277

Abstract

Disminorea merupakan nyeri haid yang menganggu aktifitas fisik wanita, sehingga seringkali saat menstruasi wanita mengalami nyeri sehingga terganggunya aktifitas dan menurunya kualitas hidup, afaktor-faktor yang berisiko terhadap dismenore primer dari berbagai literatur baik yang bersifat ginekologi, patologis sel imun maupun faktor non-medis lainnya sebagai bahan pembelajaran wanita khususnya wanita remaja untuk peningkatan kualitas hidup dengan memperbaiki faktor-faktor yang berisiko tinggi terhadap kejadian dismenorea. Tulisan ini akan membahas tentang faktor-faktor penyebab terjadinya dismenore primer berdasarkan tinjauan pustaka/literatur review. Kami menggunakan data dari beberapa referensi jurnal tinjauan sistematik, baru, dan beberapa teori dari situs yang terindeks seperti Pubmed, Scopus, Research gate, Ajog, NCBI dan lain-lain dengan menggunakan kata kunci “dismenore primer“atau nyeri haid wanita”. Peneliti menentukan batas maksimal publikasi artikel penelitian dalam 7 tahun terakhir yaitu dari 2018-2024. Hasil yang ditemukan faktor faktor yang berisiko terjadi disminore secara umum yaitu usia awal menstruasi. siklus mentsruasi, riwayat keluarga, tidak olahraga, kurang tidur, stres, cemas, dpresi, pola gaya hidup yang tidak baik, seperti konsumsi makan makanan junkfood, kurang protein, tinggi makanan berlemak, berakohol. Eksplorasi dismenore berkembang sangat pesat diharapkan dapat mengoptimalkan metode yang ada akan memainkan peran penting dalam memahami faktor-faktor yang berisiko terjadi dismenore sehingga dapat mengembangkan terapi terhadap dismenore ini di masa mendatang melalui analisis faktor-faktor penyebab tersebut untuk meningkatkan kualitas hidup wanita. Kata Kunci: disminore, faktor-faktor, kualitas hidup  
Imunitas komunitas dalam dinamika penyebaran sifilis pada remaja: Kajian naratif Kwarta, Cityta Putri; Fathiyyah, Nurul; Imeldawati, Rakhmalia; Ganisia, Ainun; Kusumawardani, Lentera Afrida
Indonesian Journal of Health Science Vol 5 No 1 (2025)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v5i1.1349

Abstract

Sexually Transmitted Infections (STIs), particularly syphilis, are a significant global health issue among adolescents, requiring an understanding of community immunity to manage its transmission. This study aims to analyze the factors influencing the spread of syphilis among adolescents and the role of community immunity in suppressing the infection rate. The research method used is a literature review from various academic databases, including PubMed, Scopus, and Google Scholar, with inclusion criteria for cohort, case-control, and cross-sectional studies, and exclusion criteria for animal and in vitro studies. The research results show that social, cultural, and economic factors play an important role in the spread of syphilis among adolescents. Community immunity in this context is not achieved through vaccination, but rather through collective behavioral changes and effective public health interventions. Community-based approaches involving families, schools, healthcare workers, and community organizations are crucial in building community immunity against syphilis. The active involvement of families and communities in providing sexual education also plays a crucial role in creating an environment that supports the sexual health of adolescents. This research concludes that a holistic and multidisciplinary community-based approach is essential to address the issue of syphilis among adolescents. Prevention and control efforts must involve changes in individual and collective behavior, as well as be supported by strong public health policies and adequate resources. By building strong community immunity, it is hoped that the spread of syphilis among adolescents can be significantly reduced, thereby improving overall public health. Infeksi Menular Seksual (IMS), terutama sifilis, merupakan masalah kesehatan global yang signifikan di kalangan remaja, memerlukan pemahaman tentang imunitas komunitas untuk mengelola penularannya. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang memengaruhi penyebaran sifilis pada remaja dan peran imunitas komunitas dalam menekan laju infeksi. Metode penelitian yang digunakan adalah penelusuran literatur dari berbagai database akademik, termasuk PubMed, Scopus, dan Google Scholar, dengan kriteria inklusi studi kohort, kasus-kontrol, dan cross-sectional, serta kriteria eksklusi studi pada hewan dan in vitro. Hasil penelitian menunjukkan bahwa faktor sosial, budaya, dan ekonomi memiliki peran penting dalam penyebaran sifilis pada remaja. Imunitas komunitas dalam konteks ini tidak dicapai melalui vaksinasi, melainkan melalui perubahan perilaku kolektif dan intervensi kesehatan masyarakat yang efektif. Pendekatan berbasis komunitas yang melibatkan keluarga, sekolah, tenaga kesehatan, dan organisasi masyarakat, sangat penting dalam membangun imunitas komunitas terhadap sifilis. Keterlibatan aktif keluarga dan komunitas dalam memberikan edukasi seksual juga berperan penting dalam menciptakan lingkungan yang mendukung kesehatan seksual remaja. Penelitian ini menyimpulkan bahwa pendekatan berbasis komunitas yang holistik dan multidisiplin sangat diperlukan untuk mengatasi masalah sifilis di kalangan remaja. Upaya pencegahan dan pengendalian harus melibatkan perubahan perilaku individu dan kolektif, serta didukung oleh kebijakan kesehatan masyarakat yang kuat dan sumber daya yang memadai. Dengan membangun imunitas komunitas yang kuat, diharapkan penyebaran sifilis pada remaja dapat ditekan secara signifikan, sehingga meningkatkan kesehatan masyarakat secara keseluruhan.
The role of inflammatory biomarkers in adolescent major depressive disorder: a systematic review Kwarta, Cityta Putri; Sari, Mike Permata; Suharti; Sundjaya, Tonny; Novitasari, Prihatini Dini; Taufik, Kumar
Berita Kedokteran Masyarakat Vol 42 No 01 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.v42i01.23244

Abstract

Purpose: Major Depressive Disorder (MDD) in adolescents is an escalating mental health problem with underlying biological pathways. Increasing evi- dence highlights the role of inflammatory response and immune dysregulation in its development and progression. This study aims to explore the role of inflammatory biomarkers in Major Depressive Disorder (MDD) among adolescent populations, elucidating their potential utility for more effective treatment strategies. Methods: A systematic review was conducted using Ebsco, PubMed, Scopus, Web of Science, and Google Scholar databases. Studies published between 2019 and 2025 that focused on adolescent MDD (aged 10-19 years) and inflammation were included. Study quality was evaluated using the Joanna Briggs Institute (JBI) tool, and narrative analyses were conducted for data synthesis. The PICOS (Population, Intervention, Comparison, Outcome, and Study Design) framework is used to ensure clarity in defining the research question and inclusion criteria. The systematic review was registered in PROSPERO (CRD420251129403). Results: A total of 29 articles met the inclusion criteria for this study. Across the included studies, elevated levels of pro-inflammatory cytokines, particularly inter- leukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α), were consistently associated with MDD in adolescents. Dysregulation of the Hypothalamic- Pituitary-Adrenal (HPA) axis and alterations in anti-inflammatory cytokines such as IL-10 were also observed. These biomarkers were linked to changes in stress hormone regulation. Conclusion: Inflammatory biomarkers play a significant role in the pathophysiology of MDD among adolescents, offering promising avenues for early detection and personalised intervention. Integrating biomarker assessment into clinical practice may improve diag- nosis and guide targeted treatments.
ANALISIS PERBANDINGAN KADAR HEMATOKRIT SAMPEL DARAH SEGERA DAN TUNDA DENGAN HEMATOLOGY ANALYZER DI UTD PMI SURABAYA TAHUN 2025 Wahyuni, Nuris Sobriyanti; Kwarta, Cityta Putri; Khairoh, Miftahul
Jurnal Teknologi Bank Darah JTBD Vol.4 No.2 (Desember 2025)
Publisher : Akademi Bakti Kemanusiaan Palang Merah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65228/jtbd.v4i2.25

Abstract

Latar belakang: Hematokrit merupakan perbandingan jumlah eritrosit dengan volume darah keseluruhan yang dihitung dalam persentase. Kerusakan eritrosit dapat menyebabkan berbagai perubahan pada parameter hematologi, termasuk hematokrit. Hematokrit yang mengukur proporsi sel darah merah dapat mengalami penurunan jika ada kerusakan eritrosit yang signifikan, karena jumlah sel darah merah berkurang. Tujuan: Untuk mengetahui adakah perbedaan kadar hematokrit sampel darah segera dan tunda dengan hematology analyzer di UTD PMI Surabaya tahun 2025. Metodologi Penelitian: Jenis penelitian ini yaitu observasional analititik yang bersifat komparatif . Penelitian ini membandingkan hasil kadar hematokrit sampel darah segera dan tunda menggunakan alat hematology analyzer dengan 38 sampel darah sebagai bahan pemeriksaan. Hasil: Hasil analisis uji statistik dengan paired T-test menunjukkan tidak ada perbedaan yang signifikan antara hasil kadar hematokrit pada pemeriksaan sampel darah segera (0 jam) dan Tunda (6 jam) dengan hematology analyzer mendapatkan nilai sign (2-tailed) = 0.379 yang berarti nilainya lebih besar dari nilai signifikansi α 0.05 atau p ˃ α (0.379 ˃ 0.05) maka Ha ditolak dan H0 diterima. Sehingga hasil uji statistik menunjukkan bahwa tidak terdapat perbedaan yang signifikan pada hasil kadar hematokrit sampel darah segera dan tunda dengan hematology analyzer. Kesimpulan: Tidak ada perbedaan kadar hematokrit sampel darah segera (0 jam) dan tunda (6 jam) dengan hematology analyzer di UTD PMI Surabaya Tahun 2025.
PENGARUH PENCUCIAN DARAH PADA KONFIRMASI GOLONGAN DARAH SISTEM ABO METODE TABUNG DI UTD PMI SURABAYA Wuru, Maria Yolanda; Kwarta, Cityta Putri; Khairoh, Miftahul
Jurnal Teknologi Bank Darah JTBD Vol.4 No.2 (Desember 2025)
Publisher : Akademi Bakti Kemanusiaan Palang Merah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65228/jtbd.v4i2.26

Abstract

Latar Belakang : Golongan darah sistem ABO sangat penting dalam transfusi darah untuk mencegah reaksi yang membahayakan. Metode tabung banyak digunakan untuk verifikasi golongan darah di Unit Transfusi Darah (UTD) PMI Surabaya. Namun, sisa plasma pada sel darah merah dapat mengganggu hasil aglutinasi dan menurunkan akurasi pemeriksaan. Pencucian darah sebelum pengujian dilakukan untuk menghilangkan plasma dan faktor pengganggu lainnya. Tujuan: Untuk mengetahui dan menganalisis pengaruh pencucian darah terhadap konfirmasi golongan darah sistem ABO metode tabung di UTD PMI Surabaya. Metode: Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross-sectional. Sampel yang digunakan dalam penelitian ini adalah darah golongan AB rhesus positif sebanyak 23 sampel diambil dengan Teknik quota ampling. Pemeriksaan dilakukan dengan mengamati derajat aglutinasi menggunakan skala ordinal dari negatif hingga 4+ menggunakan ceklist dan dianalisis menggunakan uji signifikan Wilcoxon. Hasil : Hasil penelitian menunjukkan bahwa pada darah yang tidak dicuci, 100% sampel menunjukkan tidak ada perubahan aglutinasi, sedangkan pada darah yang dicuci, terdapat perubahan aglutinasi pada 30,4% sampel dengan nilai sign.Kesimpulan : Pencucian darah memiliki pengaruh yang signifikan terhadap hasil verifikasi golongan darah sistem ABO menggunakan metode tabung di UTD PMI Surabaya, sehingga disarankan agar prosedur pencucian darah dapat diterapkan dalam praktik transfusi untuk meningkatkan akurasi pemeriksaan golongan darah.
Efektivitas Teknik Pernapasan Lamaze dalam Menurunkan Kecemasan dan Depresi pada Ibu Bersalin Primigravida Rochmayanti, Shinta Nur; Kwarta, Cityta Putri; Imeldawati, Rakhmalia; Widiyasari, Eny; Nuraenayatin, Nina; Pratiwi, Dessy; Nafiata, Ikrimah
Lontara Journal of Health Science and Technology Vol. 7 No. 1 (2026): Januari-Juni 2026
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v7i1.611

Abstract

Childbirth is a process involving hormonal changes, emotional stress, and significant physical challenges. One notable factor is the emotional stress that can induce anxiety and depression, particularly in primigravid mothers. Some efforts are needed to address this problem, one them is the use of the Lamaze breathing technique. This study aims to determine the effectiveness of the Lamaze breathing technique in reducing labor pain, thereby impacting maternal anxiety and depression. The study employed a quasi-experimental design with a pre-test and post-test approach. The study sample consisted of 40 primigravid mothers, randomly assigned to either the intervention group (n=20), which received Lamaze breathing technique training, or the control group (n=20), which received standard midwifery care. The results of the study demonstrated a significant decrease in anxiety and depression scores in the intervention group following the Lamaze breathing technique training (p<0.001), and no significant changes in anxiety scores (p = 0.672) and depression scores (p = 0.785) in the control group. It can be concluded that the Lamaze breathing technique is effective in reducing anxiety and depression levels in primiparous mothers.
Dukungan Sosial dan Faktor Lain Yang Mempengaruhi Kualitas Hidup Wanita Dengan HIV/AIDS Ganisia, Ainun; Fathiyyah, Nurul; Imeldawati, Rakhmalia; Kwarta, Cityta Putri
Lontara Journal of Health Science and Technology Vol. 7 No. 1 (2026): Januari-Juni 2026
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v7i1.618

Abstract

People with HIV/AIDS not only need medication to reduce physical discomfort, but also need social support to overcome psychological anxiety and restlessness. Social support is critical in maintaining good physical and mental health. This study aims to analyze the social support status of women with HIV/AIDS and explore other factors that affect their quality of life in Kecamatan Patrang, Kabupaten Jember. The research method used was cross-sectional with convenience sampling and data collection through questionnaires with SSRS (Social Support Rating Scale) within three months from March to May 2025, with a sample of 92 women with HIV/AIDS. It is known that there is a significant relationship between emotional support (p = 0.01) and assessment support (p = 0.03), as well as other factors such as the duration of ARV therapy (p = 0.03), with the quality of life of women with HIV/AIDS. These findings are expected to provide a basis for interventions, including the formation of peer-support groups, counseling programs focused on strengthening self-esteem, and training for families and communities to provide appreciation and respect to women with HIV/AIDS, which ultimately improves their health and quality of life.
ANALISIS KADAR HEMOGLOBIN WHOLE BLOOD BERDASARKAN DURASI PENYIMPANAN DI UTD RSUD BAHTERAMAS Widuri, Sasi; Lentera Afrida Kusumawardani; Kwarta, Cityta Putri; Amalia, Yustisia; Samsulhadi, Wiwid
Jurnal Medicare Vol. 5 No. 1 (2026): JANUARY 2026
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v5i1.376

Abstract

Maintenance of hemoglobin (Hb) levels in Whole Blood (WB) is crucial to ensure the quality and efficacy of transfusions, as the storage process can induce biochemical changes. Preliminary observations at RSUD Bahteramas indicated fluctuations in Hb levels during the early storage period. This study aimed to analyze the differences in Hb levels between the 5th and 10th day of WB storage at the Blood Transfusion Unit of RSUD Bahteramas. An analytical study with a cross-sectional approach was conducted on 10 WB samples selected using simple random sampling. Hb levels were measured using the LANDWIND Hematology Analyzer, and data were analyzed descriptively and with an independent t-test. Results showed that on day 5, only 50% of samples met quality specifications, whereas by day 10, compliance increased to 90%. A significant difference in Hb levels was observed between the two storage periods (p<0.05). It is concluded that optimal cold chain management can maintain Hb stability up to the 10th day of storage.
PENGARUH PENGGUNAAN ANTIKOAGULAN DAN TANPA ANTIKOAGULAN TERHADAP HASIL CROSSMATCHING Reswari, Putu Ayu Dhana; Lentera Afrida Kusumawardani; Kwarta, Cityta Putri; Amalia, Yustisia; Widuri, Sasi
Jurnal Medicare Vol. 5 No. 1 (2026): JANUARY 2026
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v5i1.377

Abstract

Pre-transfusion testing is a mandatory procedure to ensure compatibility between donor and recipient blood; therefore, the selection of sample type is a critical factor in determining the accuracy of test results. The use of blood samples with anticoagulant EDTA or without anticoagulant (serum) is suspected to influence crossmatching outcomes. This study aimed to analyze the effect of sample type on crossmatching results at the Blood Transfusion Unit of PMI Nunukan Regency. A pre-experimental study with a static group comparison design was conducted on 30 patient samples using a total sampling technique. Crossmatching examinations were performed using the gel test method and analyzed with the McNemar test. The results showed that all EDTA samples (100%) were incompatible, while serum samples showed 30% compatible and 70% incompatible results. Statistical analysis indicated a significant difference (p=0.000). It is concluded that the use of serum without anticoagulant is more recommended as it reduces false-positive reactivity and improves the efficiency of blood transfusion services.
PENGARUH OLAHRAGA JOGGING TERHADAP KADAR HEMOGLOBIN PADA PENDONOR RUTIN DI UDD PMI KABUPATEN LOMBOK BARAT Samsulhadi, Wiwid; Lentera Afrida Kusumawardani; Kwarta, Cityta Putri; Amalia, Yustisia; Reswari, Putu Ayu Dhana
Jurnal Medicare Vol. 5 No. 1 (2026): JANUARY 2026
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v5i1.378

Abstract

Maintenance of hemoglobin (Hb) levels in blood is an essential requirement for regular donors to ensure donor eligibility and recipient safety. Observations at UDD PMI West Lombok indicated a high rate of donor disqualification due to low Hb levels. This study aimed to analyze the relationship between jogging activity and Hb levels among regular donors at UDD PMI West Lombok Regency. An analytical observational study with a cross-sectional design was conducted on 91 respondents selected using the Slovin formula. Physical activity data were collected through a Guttman scale questionnaire, while Hb levels were measured using the Hemo Control device. Data were analyzed using the Chi-Square test. The majority of respondents were male (73%), with the dominant age group being 40–49 years (42%). A total of 53% of respondents regularly performed jogging, and 62% had Hb levels within acceptable specifications. The Chi-Square test showed a p-value of 0.001 (<0.05). There was a significant relationship between jogging activity and hemoglobin levels among regular donors.