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All Journal Jurnal Intelektualita: Keislaman, Sosial, dan Sains CHEMPUBLISH JOURNAL Acta Pharmaciae Indonesia : Acta Pharm Indo Indonesian Journal on Learning and Advanced Education (IJOLAE) Stannum : Jurnal Sains dan Terapan Kimia JIPI (Jurnal IPA dan Pembelajaran IPA)
syarpin, syarpin
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Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Medicine & Pharmacology Physics Social Sciences

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Uji Fitokimia dan Antioksidan Ekstrak Etanol Buah Terung Asam (Solanum ferox L) syarpin, syarpin; Nugroho, Wahyu; Rahayu, Sari
Acta Pharmaciae Indonesia Vol 6 No 2 (2018): Acta Pharmaciae Indonesia Volume 6 No.2 Tahun 2018
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (164.854 KB)

Abstract

Penelitian ini bertujuan untuk mengetahui kandungan senyawa kimia dan aktivitas antioksidan ekstrak etanol buah terung asam (Solanum ferox L). untuk mencapai tujuan tersebut digunakan beberapa cara yaitu dengan melakukan uji fitokimia (alkaloid, terpenoid, steroid, saponin, fenolat secara umum dan flavonoid. Hasil dari uji fitokimia menunjukkan reaksi positif terhadap beberapa pereaksi yaitu uji alkaloid, uji terpenoid, uji fenolat dan uji flavonoid. Sedangkan uji steroid dan saponin tidak memberikan hasil yang postif terhadap pereaksi. Selanjutnya melakukan uji antioksidan dan diperoleh nilai  IC50 sebesar 177,16 ppm. Sehingga dapat disimpulkan ekstrak etanol buah terung asam memiliki aktivitas sedang.
Analisis Substansi Najis: Studi Awal Perancangan Alat Deteksi Najis Mukhoffafah dan Mutawassithoh Ali, Nuraliah; Pratiwi, Putri Fransiska Purnama; Syarpin, Syarpin
Intelektualita Vol 10 No 2 (2021): Jurnal Intelektualita: Keislaman, Sosial, dan Sains
Publisher : Wakil Rektor III Bidang Kemahasiswaan dan Kerjasama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/intelektualita.v10i2.9921

Abstract

Penelitian ini bertujuan untuk menganalisis kandungan najis mutawassithoh dan mukhoffafah sebagai suatu studi awal pengembangan inovasi berupa desain alat deteksi najis yang nantinya dapat dimanfaatkan untuk mendeteksi keberadaan najis yang melekat pada tubuh, pakaian, tempat/alat ibadah. Metode penelitian yang digunakan adalah metode framing dan studi literatur. Penelitian ini dimulai dari kegiatan penetapan sampel. Total sampel ditentukan yakni air seni bayi laki-laki yang belum diberi makan apa-apa selain ASI dan air seni orang dewasa. Selanjutnya data akan dianalisis melalui reduksi data, penyajian data, dan verifikasi. Penelitian ini menunjukkan bahwa terdapat perbedaan pada urine kategori mutawassithoh dan mukhoffafah dari segi koefisien serapan liniernya, kandungan amonia dan persentase bakteri. Mendeteksi najis dapat menggunakan sensor fisika dan sensor kimia. Sensor fisika mendeteksi suatu besaran berdasarkan hukum-hukum fisika, yaitu seperti sensor cahaya, suara, gaya, kecepatan, percepatan, maupun sensor suhu. Sensor kimia mendeteksi jumlah zat kimia dengan jalan mengubah besaran kimia menjadi besaran listrik yang melibatkan beberapa reaksi kimia, seperti misalnya pada sensor pH, sensor oksigen, sensor ledakan, serta sensor gas.
Exploring the Viability of Waste Durian (Durio zibethinus) Seeds and Cempedak (Artocarpus integer) Seeds as Nutritive Resources: An Analytical Study of Their Suitability via Alcohol and Glucose Assays Syarpin, Syarpin; Saputra, Rizki Rachmad; Haliza , Nur; Anista, Anista; Yanti, Helda; Sisilya, Tahsya Amanda; Fahmi, Rifaldi Lutfi
Chempublish Journal Vol. 7 No. 2 (2023): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v7i2.27983

Abstract

Durian (Durio zibethinus) and Cempedak (Artocarpus integer), prominent staples in Indonesia, harbor seeds that can be harnessed for the production of 'Tapai', a traditional fermented product. This fermentation process within cempedak and durian seeds manifests in the generation of alcohol and glucose at discernible thresholds. Motivated by the prevalent underutilization of durian and cempedak seeds leading to wastage, this study aims to assess the viabilities of Tapai derived from these seeds by scrutinizing their alcohol and glucose profiles. Employing a quantitative descriptive approach, the research centers on cempedak and durian seed Tapais as the primary samples. Focusing on variables like alcohol and glucose content, the investigative technique incorporates distillation and titration using the Luff Schoorl method. Results are subsequently organized in frequency distribution tables following coding and tabulation. Observations reveal that alcohol and glucose levels in cempedak seed Tapai on the 10th day stand at 0.00% and 30.05%, respectively, while on the 15th day, they escalate to 4.88% and 41.92%. In the case of durian seed Tapai, levels on the 10th day are recorded at 4.88% for alcohol and 36.90% for glucose. On the 15th day, these figures rise to 16.57% for alcohol and 46.53% for glucose. Ultimately, this study underscores that the alcohol and glucose concentrations in cempedak and durian seed Tapais experience progressive augmentation over a 5-day period, rendering them safely consumable in moderate quantities.
Phytochemical Analysis and Study of Molecular Docking of Leucaena leucocephala Leave Extract as Anticancer Ariefin, Mokhamat; syarpin, Syarpin; Harianto, Bibit
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4387

Abstract

Cancer is a disease caused by unnatural cell growth in the body. It has become a disease with a high mortality rate in the world. Several therapies have been developed for cancer treatment, one of which is the exploration of the bioactivity of compounds contained in potentially medicinal plants. One of the potential medicinal plants that grows in Central Kalimantan province is L. leucocephala. In this study, the potential of L. leucocephala leaf extract was explored through phytochemical tests and molecular docking approaches. Based on the phytochemical test, it was found that L. leucocephala leaf extract contains flavonoids, terpenoids, and steroids. Based on the test results, a literature study was conducted on the flavonoids and terpenoids content in L. leucocepala leaf extract and molecular docking studies were conducted. Seven dominant compounds of L. leucocephala consisting of flavonoids and terpenoids were tested for their potential as inhibitors of receptor tyrosine kinase. The molecular docking results showed that flavonoid ligands (1-6) had more negative binding affinity values compared to the drug sunitinib, a common drug for cancer therapy, while terpenoid ligand (7) had less favorable binding energy. Based on the Lipinski rule of five test, ligands 1, 2, 4, and 5 fulfill all the criteria given as drug candidates, while ligands 3, 6, and 7 only fulfill 3 out of 5 criteria. Based on Lipinski rule of five and molecular docking, ligand 1,2,4, and 5 has potential to be anticancer.
Transcript-Based Lesson Analysis: The Analysis of Classroom Communication in Chemistry Implementing Case-Based and Project-Based Learning Winarti, Atiek; Iriani, Rilia; Butakor, Paul Kwame; Meiliawati, Ruli; Syarpin, Syarpin
Indonesian Journal on Learning and Advanced Education (IJOLAE) Vol. 6, No. 1, January 2024
Publisher : Faculty of Teacher Training and Education, Universitas Muhammadiyah Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ijolae.v6i1.23160

Abstract

Previous research studies found that Case-Based Method (CBM) and Project-Based Learning (PBL) models increase student motivation, critical thinking, and problem-solving. However, so far, the success of implementing these models has mostly been based on learning outcomes. Not many research studies have been carried out to reveal the effectiveness of these models by analyzing the learning process. This research is a qualitative descriptive study that aims to analyze classroom communication on solving problems in Chemistry lessons implementing the CBM and PBL models using Transcript Based Lesson Analysis (TBLA). TBLA is an analysis method based on communication occurring in the classroom. In this research, TBLA analyzes the classroom communication on solving problems in the Wood Chemistry course at the Department of Chemistry Education, Lambung Mangkurat University, Indonesia. A total of 26 students were involved. The classroom communication was recorded by camcorders and the data were transformed into transcripts.  The data was processed using Excel to produce a TBLA graph. The results show that (1) the ratio of lecturer and student communication intensity using the CBM model in the classroom is 1:3, and the PBL model is 1:1. (2) The CBM model provides a good environment for the development of student HOTS through in-depth multi-directional communication patterns in the problem-solving process. (3) PBL builds better collaboration between students compared to the CBM model. This research implies that the quality of classroom communication can be improved by integrating the HOTS questions and independent group work as implemented in the CBM and PBL models.
E-Module of the Human Digestive System with Self-Directed Learning Readiness Framework to Improve Students' Science Literacy Syahira, Hany Qisthina; Pursitasari*, Indarini Dwi; Retnowati, Rita; Syarpin, Syarpin
Jurnal IPA & Pembelajaran IPA Vol 9, No 4 (2025): DECEMBER 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jipi.v9i4.48969

Abstract

Science literacy is a crucial competency in addressing the challenges of 21st-century learning. Low science literacy in biology subjects is important in science education. This research aims to develop e-modules for the human digestive system based on the self-directed learning readiness (SDLR) framework to enhance students' science literacy and independent learning readiness. This development research uses the analyze, design, develop, implement, and evaluate (ADDIE) model. Data were collected through expert validation tests, science teacher assessments, science literacy tests, SDLR questionnaires, implementation observations, and student response questionnaires to e-modules. The data was analyzed descriptively, quantitatively, and using N-Gain calculations. The results of the study demonstrate that the e-module on the human digestive system is proven to be valid, based on expert assessment with Aiken's V index of 0.84. The results of the teacher's assessment also demonstrated high validity, with content validity ratio (CVR) and contet validity index (CVI) scores of 0.98 and 0.99, respectively. The results of implementing the e-module showed an increase in science literacy and SDLR, with N-gains of 0.349 and 0.426 in the medium category. The highest increase occurred in the competence of explaining scientific phenomena and the desire to learn, with an N-gain of 50% each. Students responded positively to the e-module because it is easily accessible, attractive, and able to motivate students to learn independently. Thus, it can be concluded that the e-module on the human digestive system, based on self-directed learning readiness, can improve science literacy and students' readiness for independent learning
Co-Authors A.A. Ketut Agung Cahyawan W Ali, Nuraliah Anista, Anista Atiek Winarti Butakor, Paul Kwame Fahmi, Rifaldi Lutfi Haliza , Nur Harianto, Bibit Indarini Dwi Pursitasari Meiliawati, Ruli Mokhamat Ariefin Pratiwi, Putri Fransiska Purnama Rahayu, Sari Rilia Iriani Rita Retnowati Rizki Rachmad Saputra Sisilya, Tahsya Amanda Syahira, Hany Qisthina Yanti, Helda