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All Journal Sainteks Jurnal Periodic Jurusan Kimia UNP Jurnal Sumberdaya Hayati CHEESA: Chemical Engineering Research Articles JURNAL PENDIDIKAN TAMBUSAI Eksakta : Berkala Ilmiah Bidang MIPA Pelita Eksakta Stannum : Jurnal Sains dan Terapan Kimia SECONDARY : Jurnal Inovasi Pendidikan Menengah (JIPM) Afeksi: Jurnal Penelitian dan Evaluasi Pendidikan BIOCHEPHY: Journal of Science Education ALSYS : Jurnal Keislaman dan Ilmu Pendidikan MASALIQ: Jurnal Pendidikan dan Sains Journal of Multidisciplinary Inquiry in Science, Technology and Educational Research
Parbuntari, Hesty
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Journal : CHEESA: Chemical Engineering Research Articles

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Identification of Flavonoid Compounds in Ethanol Extract of Majapahit plant (Crescentia cujete) Leaves and their Potential as Anticancer Martha, Rahma Diyan; Fatimah, Fatimah; Danar, Danar; Parbuntari, Hesty
CHEESA: Chemical Engineering Research Articles Vol. 6 No. 1 (2023)
Publisher : Universitas PGRI Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/cheesa.v6i1.14056.34-48

Abstract

The Majapahit plant is commonly found in Indonesia but is rarely used due to a lack of information about its potential. One of the secondary metabolites commonly found in this plant are flavonoids. Therefore, this study aims to determine the distribution of flavonoid compounds in the Majapahit plant, particularly their potential as anticancer activty. Leaf material from Majapahit plants was extracted using the maceration technique, while the flavonoid compounds in the extract were identified using LCMS (Shimadzu LCMS-8040 LC/MS). The identification results showed that about 97 compounds were detected, including 14 flavonoids. The flavonoid compounds found include Quercetin, Chlorogenic acid, Kaempferol 3-O rhamnoside, Acacetin 7-rutinoside, Fortunellin, Kaempferol 3-[6"-(3-hydroxy-3-methyl glutarl) glucoside], Didymin, Diosmin, Hesperidin, Rutin, Citrusoside C, Citrusoside D, Narirutin 4'-glucoside, and Kaempferol 3-[6"-(3-hydroxy-3-methylglutaryl)glucoside] -7-glucoside. The highest composition of the identified flavonoid compounds was found in Kaempferol 3-O rhamnoside, with a 3.90%
The Antibacterial Potential of Ethyl Acetate Fraction from Plectranthus amboinicus Leaves and Identification of Active Compounds Using LC-MS Martha, Rahma Diyan; Safitri, Yunita Diyah; Lestari, Nasa Bela Dwi; Danar, Danar; Parbuntari, Hesty; Maida, Margarita Claudya; Muadifah, Afidatul; Huda, Choirul
CHEESA: Chemical Engineering Research Articles Vol. 7 No. 1 (2024)
Publisher : Universitas PGRI Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/cheesa.v7i1.13826.15-23

Abstract

The Indian Borage plant (Plectranthus amboinicus) is a traditional medicinal ingredient in Indonesia, containing flavonoids, alkaloids, polyphenols, saponins, and essential oils. Therefore, this study aimed to determine the antibacterial activity of P. amboinicus leaves ethyl acetate fraction using the disc diffusion method and identify the composition with LC-MS. The antibacterial activity test was conducted with concentration variations of 15%, 20%, and 25% with Chloramphenicol 500 mg and 5% DMSO as a positive and negative control, respectively. The results showed that the ethyl acetate fraction at a concentration of 20% had the largest inhibition zone diameter, with an average of 30 mm. The LC-MS results identified 115 compounds, and the highest concentration values were found in kaempferol 3-(6”-caffeoylglucoside) and kaempferol 3-glucosyl-(1→2) galactosyl-(1→2)-glucoside, with a composition of 3.26109% and 3.26141%, respectively.
Co-Authors Aini, Syamsi Alizar, Alizar Annisa Annisa Asnah, Nur Azura, Nur Azzahra, Wenalda Hanifah Budhi Oktavia Danar Danar Danar, Danar Deski Beri Desy Kurniawati Erwan, Meriska Octavia Fajri, Ayu Insa fatimah Fatimah Febri Perdana, Keke Febrianti, Latifah Intan Firdaus, Salsabila Husna, Miftahul Illahi, Annisa Ridho Kholifah, Siti Nurriyatul Kiki Amelia, Kiki Lestari, Nasa Bela Dwi Mahmud Mahmud Maida, Margarita Claudya MARTHA, RAHMA DIYAN Martha, Rahma Dyan Maulidina, Freshilla Megawati - Miftahul Rahmi, Miftahul Muadifah, Afidatul Octaviana, Nur Putri, Reza Athia Rahma Diyan Martha Safitri, Yunita Diyah Saputra, Anwar Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Yuliandari, Fadhira Yulistia, Siska