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All Journal Universa Medicina PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Ners Jurnal Kesehatan Tambusai MAHESA : Malahayati Health Student Journal Pancasakti Journal Of Public Health Science And Research eJournal Kedokteran Indonesia Eduvest - Journal of Universal Studies Jurnal Kedokteran Meditek Malahayati International Journal of Nursing and Health Science
Pertiwi, Junita Maja
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Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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ANALISIS PERSEPSI DAN PENGETAHUAN MASYARAKAT TERHADAP PENYAKIT KUSTA DI KELURAHAN MASARANG, KABUPATEN MINAHASA, SULAWESI UTARA Pati, Josefa M.; Wungouw, Herlina I. S.; Pertiwi, Junita Maja
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.33858

Abstract

Kabupaten Minahasa masih menjadi salah satu kabupaten di Indonesia dengan masalah kusta yang belum mencapai target eliminasi nasional. Rendahnya angka kesembuhan dan jumlah penderita yang terus bertambah menjadi masalah kesehatan klasik yang belum terselesaikan. Penelitian ini bertujuan untuk mengetahui persepsi dan pengetahuan masyarakat terhadap penyakit kusta di Kelurahan Masarang, Kabupaten Minahasa dengan menggunakan pendekatan kualitatif. 13 informan yang terdiri atas petugas kesehatan, tokoh masyarakat, tetangga dan penderita kusta dipilih untuk mendapatkan gambaran tentang persepsi dan pengetahuan. Menggunakan metode wawancara mendalam dan content analysis, kami menemukan disparitas pengetahuan pada kelompok informan. Petugas kesehatan selaku ujung tombak penganggulangan kusta memiliki pengetahuan yang sangat baik tentang kusta, namun pada kelompok tokoh masyarakat hingga penderita, pengetahuan cenderung menurun kearah kurang baik. Hal ini diakibatkan oleh perbedaan tingkat pendidikan dan keterpaparan akan informasi kusta. Kami juga menemukan hal menarik pada persepsi informan, meskipun pengetahuan mereka kurang namun kami menemukan secara umum persepsi mereka baik. Hal ini tergambar dalam interaksi sosial mereka, dimana mereka memperlakukan penderita kusta dengan baik. Rasa takut akan kusta hanya terjadi di fase awal saja, seiring berjalan waktu keberterimaan dalam lingkungan sosial menjadi baik. Untuk meningkatkan kualitas penelitian di masa depan, kami menyarankan perlunya pelibatan mediator dan penggunaan metode wawancara mendalam yang lebih baik untuk mengatasi kesulitan mendapatkan informasi pada penderita kusta.
Prediksi Gangguan Kognitif Ringan Menggunakan Pencitraan Resonansi Magnetik dan Deep Learning: Sebuah Studi Meta-Analisis Setiawan, Budi; Wariki, Windy Mariane Virenia; Warouw, Finny; Momole, Ansye Grace Nancy; Tumewah, Rizal; Pertiwi, Junita Maja
Jurnal Kedokteran Meditek Vol 31 No 2 (2025): MARCH
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i2.3463

Abstract

Introduction: Mild Cognitive Impairment (MCI) is a condition characterized by cognitive decline that does not interfere with daily activities but increases the risk of progressing to Alzheimer's Dementia (AD). Early detection of MCI progression to AD is crucial for early intervention. Purpose: The purpose of this meta-analysis to evaluate the performance of Convolutional Neural Networks (CNNs), an artificial intelligence used to analyze complex data such as images, in predicting the conversion of MCI to AD using MRI data. Methods: A meta-analysis was conducted following PRISMA guidelines, utilizing articles from PubMed and Wiley Online Library. Inclusion criteria focused on studies that used CNN in conjunction with MRI to diagnose MCI. A total of 39 articles with 40 comparative studies were analyzed. Results: The CNN showed an average accuracy of 0.7910 (p < 0.0001), sensitivity of 0.7698, specificity of 0.8467, and an Area Under the Curve (AUC) of 0.8063. High heterogeneity (I² = 90.90%) indicated significant variation across studies. Sub meta-analysis revealed consistent performance despite the heterogeneity. Conclusion: CNN is potentially useful for predicting the progression of MCI to AD. Further research is needed to address heterogeneity, improve algorithms, expand datasets, and include more diverse populations.
Influence of Carotid Intima Media Thickness on The Patient's Memory Function Fails Heart with Ejection Fraction Left Ventricle Descends Tongku, Aurelia Sartika; Pertiwi, Junita Maja; Tangkudung, Gilbert; Kembuan, Mieke A.H.N.; Momole, Ansye G.N.
Eduvest - Journal of Universal Studies Vol. 5 No. 6 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i6.51267

Abstract

Heart failure (HF) with reduced left ventricular ejection fraction (LVEF) is frequently associated with cognitive decline, including memory impairment. This study investigates the relationship between carotid intima-media thickness (CIMT), a marker of subclinical atherosclerosis, and specific memory domains immediate, recall, and recognition in patients with reduced LVEF. A cross-sectional study was conducted on 52 HF patients at Prof. Dr. R.D. Kandou Hospital. Memory function was assessed using the Word List Memory Test, and CIMT was measured via carotid ultrasound. Regression analysis showed that increased CIMT in the left common carotid artery (CCA Sinistra) was significantly associated with lower immediate and recognition memory performance. Furthermore, elevated CIMT in both carotid arteries was negatively correlated with recall memory. These findings highlight a potential vascular contribution to cognitive impairment in HF patients, suggesting that subclinical carotid atherosclerosis may impair cerebral perfusion. The study provides clinical insight into the importance of vascular assessment in managing cognitive health in HF populations. Early detection of carotid pathology may offer a strategy to prevent or reduce cognitive decline in these patients.
The Relationship Between Pesticide Use and Cognitive Impairment in an Agricultural Community of Tomohon City, North Sulawesi Masengi, Angelina Stevany Regina; Mambo, Christi Diana; Nangoy, Edward; Posangi, Jimmy; Lasut, Marthen Theogives; Pertiwi, Junita Maja; Warouw, Finny; Sanggelorang, Yulianty; Sengkey, Daniel Febrian; Mamahit, Juliet Merry Eva
eJournal Kedokteran Indonesia Vol. 13 No. 1 (2025): Vol 13, No. 1 - April 2025
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23886/ejki.13.961.42

Abstract

This study investigates the cognitive effects of pesticide exposure on agricultural workers from a village in Tomohon City, North Sulawesi, Indonesia. Employing a cross-sectional design from July to September 2024. This study assessed the demographic characteristics, pesticide exposure patterns, and cognitive function of 97 participants aged 18 using the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA-INA.The findings reveal a clear association between direct and indirect pesticide exposure and cognitive impairment. Direct exposure was linked to slightly lower cognitive scores than indirect exposure, with both groups scoring below established thresholds for normal cognitive function, particularly in memory, attention, and executive functions. Inconsistent use of personal protective equipment was noted among participants, with common immediate symptoms including visual disturbances and memory deficits following pesticide application. These results suggest that minimal pesticide exposure may contribute to cognitive decline, potentially accelerating age-related impairments. The underlying neurotoxic mechanisms likely involve oxidative stress, mitochondrial dysfunction, and neuroinflammation, which disrupt neuronal integrity. These findings underscore the urgent need for enhanced occupational health policies, stricter safety measures, and further research to mitigate the cognitive risks of pesticide exposure in agricultural populations.
Studi Meta-Analisis Transcranial Doppler Terhadap Glasgow Outcome Score Pada Cedera Otak Traumatik William, William; Tumewah, Rizal; Ngantung, Denny; Pertiwi, Junita Maja; Tumboimbela, Melke; Wariki, Windy Mariane Virenia
MAHESA : Malahayati Health Student Journal Vol 5, No 7 (2025): Volume 5 Nomor 7 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i7.18851

Abstract

ABSTRACT Traumatic brain injury (TBI) through primary and secondary brain injury causes ischemic, hypoxic, cerebral edema, increased intracranial pressure, which are related to physiological, emotional damage and disability. Transcranial Doppler (TCD) as a diagnostic tool can monitor increased intracranial pressure through hypoperfusion and also monitor vasospasm. This meta-analysis study aims to determine TCD as a diagnostic tool in predicting outcomes in TBI cases. Observational studies were taken on TCD examination in TBI cases. Clinical outcomes were assessed based on the Glasgow Outcome Score (GOS), Glasgow Outcome Score-Extended (GOS-E), and mortality. Secondary outcomes were the cut-off values of the Pulsatility Index (PI) and Lindegaard Ratio (LR) related to GOS, GOSE and mortality. Abnormal TCD values in TBI cases would have a >11 times greater likelihood of poor GOS (OR 11.51, 95% CI 7.75 to 17.10). Abnormal TCD had a >11 times greater likelihood of causing death compared to normal TCD (OR 11.05, 95% CI 5.99 to 20.40). Hypoperfusion on TCD had a >6 times greater likelihood of being associated with poor GOS (OR 6.33, 95% CI 0.28 to 144.48) and had a >22 times greater likelihood of causing death compared to vasospasm on TCD (OR 22.86, 95% CI 0.70 to 751.27). ROC curve analysis showed that the PI cut-off value of 1.03 and LR 3.3 were associated with poor GOS. TCD can be used as a diagnostic tool to predict poor GOS outcomes and mortality in TBI cases. Keywords: Transcranial Doppler, Glasgow Outcome Score, Traumatic Brain Injury ABSTRAK Cedera otak traumatik (COT) melalui cedera otak primer dan sekunder menyebabkan proses iskemik, hipoksik, edema serebral, kenaikan tekanan intrakranial, yang berkaitan dengan kerusakan fisiologis, emosional dan disabilitas. Transcranial Doppler (TCD) sebagai alat penunjang diagnostik dapat memantau kenaikan tekanan intrakranial melalui hipoperfusi dan juga memantau vasospasme. Studi meta-analisis ini bertujuan untuk menentukan TCD sebagai alat penunjang diagnostik dalam memprediksi luaran pada kasus COT. Studi observasional pemantauan TCD pada kasus COT diambil untuk dilakukan meta-analisis. Luaran klinis dinilai berdasarkan Glasgow Outcome Score (GOS), Glasgow Outcome Score-Extended (GOS-E), dan mortalitas. Luaran sekunder berupa nilai cut-off Pulsatility Index (PI) dan Lindegaard Ratio (LR) yang berhubungan dengan GOS, GOSE dan mortalitas. Nilai abnormal pada TCD akan memiliki kemungkinan >11 kali luaran GOS buruk (OR 11.51, 95% CI 7.75 to 17.10). TCD abnormal memiliki kemungkinan >11 kali menyebabkan kematian dibandingkan TCD normal (OR 11.05, 95% CI 5.99 to 20.40). Hipoperfusi pada TCD memiliki kemungkinan >6 kali berkaitan dengan GOS buruk (OR 6.33, 95% CI 0.28 to 144.48) dan memiliki kemungkinan >22 kali menyebabkan kematian dibandingkan vasospasme pada TCD (OR 22.86, 95% CI 0.70 to 751.27). Analisis kurva ROC memperlihatkan nilai cut-off PI 1.03 dan LR 3.3 berkaitan dengan GOS yang buruk. TCD dapat digunakan sebagai alat diagnostik untuk memprediksi luaran GOS buruk dan mortalitas pada kasus COT. Kata Kunci: Transcranial Doppler, Glasgow Outcome Score, Cedera Otak Traumatik 
Effectiveness of non-invasive transcranial magnetic stimulation therapy as a therapy for post-stroke visuospatial impairment: A meta-analysis Lapian, Albertus Theo; Warouw, Finny; Momole, Ansye Grace Nancy; Pertiwi, Junita Maja; Tangkudung, Gilbert
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 2 (2025): Volume 8 Number 2
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i2.552

Abstract

Background: Visuospatial disorders refer to deficits in attention, exploration, and interaction with the contralateral side of space that cannot be attributed to primary sensory or motor dysfunction. These disorders are usually caused by lesions in the right hemisphere due to cerebral circulation disorders, such as stroke. Transcranial Magnetic Stimulation (TMS) has emerged as a noninvasive treatment option for addressing visuospatial deficits. Purpose: To evaluate the effectiveness of TMS as a therapy for visuospatial disorders in post-stroke patients. Method: This study was conducted using randomized controlled trials (RCTs) comparing TMS with sham treatment for post-stroke visuospatial impairment identified through searches in Google Scholar, PubMed/Medline, Clinical Key, Wiley Online, Science Direct, ResearchGate, and Neurona. A meta-analysis was conducted to assess the efficacy of TMS therapy for improving visuospatial deficits in post-stroke patients. Results: A total of 189 studies on TMS were identified with four homogeneous articles finally included in the meta-analysis. The analysis combined visuospatial assessments using the Motor-Free Visual Perception Test (MVPT), ​​Star Cancellation Test (SCT), Albert Test (AT), and Line Bisection Test (LBT). The meta-analysis revealed significant findings for the MVPT, with a weighted mean difference (WMD) of 2.43 (95% CI: 1.86 to 3.01, p < 0.001). For LBT, WMD was 2.69 (95% CI: 2.04 to 3.34, p = 0.020). Conclusion: The improvements in visuospatial function observed in participants undergoing TMS suggest that TMS may serve as a potential therapeutic option for post-stroke patients with visuospatial impairment.
Analysis of Barriers to the Implementation of Electronic Medical Records in the Outpatient Clinic of Gunung Maria Hospital, Tomohon Goni, Angelina; Pertiwi, Junita Maja; Wariki, Windy
Pancasakti Journal Of Public Health Science And Research Vol 5 No 2 (2025): PJPHSR
Publisher : Fakultas Kesehatan Masyarakat, Universitas Pancasakti, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47650/pjphsr.v5i2.1908

Abstract

The implementation of EMR is expected to improve the quality of healthcare services by facilitating faster access to patient data, reducing recording errors, and enhancing coordination among medical personnel. However, various challenges have been identified in practice, which hinder the system’s effectiveness. This study aims to analyze the barriers to EMR implementation in the Outpatient Clinic of Gunung Maria Hospital, Tomohon. A qualitative approach was employed, using in-depth interviews with informants directly involved in the EMR implementation process. The findings reveal that the barriers arise from multiple aspects. From the human resources perspective, additional time and training are needed to enable staff to adapt to the new system. In terms of technological infrastructure, unstable network connectivity and the limited availability of hardware, such as computers and printers in certain service units, hamper the data input process. Regarding software, the existing system does not fully meet the hospital’s operational needs. Procedurally, insufficient dissemination of the standard operating procedures (SOPs) has resulted in some staff not fully understanding the system’s workflow. Furthermore, the evaluation aspect remains problematic due to the absence of a fully functioning monitoring mechanism. External disturbances, such as power outages, have also contributed to service delays by disrupting the electronic documentation process. In conclusion, the EMR implementation at the outpatient clinic still faces various technical and non-technical challenges. Therefore, improvements and strengthening efforts across multiple aspects are required to ensure that the EMR system can operate more effectively and efficiently in supporting the enhancement of healthcare service quality.
Hubungan Mutu Pelayanan Kesehatan Gigi dan Mulut Terhadap Kunjungan Pasien di Puskesmas Tepa Slarmanat, Intan Indah S.; Pertiwi, Junita Maja; Kaunang, Wulan Pingkan Julia
Jurnal Ners Vol. 9 No. 3 (2025): JULI
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i3.47933

Abstract

Abstrak Mutu pelayanan kesehatan merupakan proses berkelanjutan yang memantau pemberian layanan dan hasilnya untuk menilai berbagai faktor frekuensi kunjungan pasien yang memengaruhi layanan kesehatan. Dengan cara ini, masalah dapat ditemukan dan sumbernya ditangani, yang mengarah pada kesehatan dan kesejahteraan yang lebih baik bagi mereka yang menggunakan layanan kesehatan Tujuan penelitian ini yaitu untuk menganalisis hubungan mutu pelayanan kesehatan gigi dan mulut terhadap kunjungan pasien di Poliklinik Gigi dan Mulut di puskesmas Tepa melalui variabel Tangible (Wujud), Reliability (Kehandalan), Responsiveness (Cepat Tanggap), Assurance (Kepastian) dan Emphaty (Empati). Metode kuantitatif observasional analitik dengan pendekatan potong lintang. Penelitian dilaksanakan pada periode Januari-maret Tahun 2025 yang bertempat di Puskesmas Tepa, Kecematan Pulau Babar Barat, Kabupaten Maluku Barat Daya. Sampel penelitian yaitu 76 responden. Teknik yang digunakan adalah purposive sampling. Data hasil survey dianalisis dengan menggunakan uji chi-square dan regeresi logistic. Hasil penelitian ini menunjukkan bahwa Tangible (Wujud), Reliability (Kehandalan), Responsiveness (Cepat Tanggap), Assurance (Kepastian) dan Emphaty (Empati) memiliki hubungan yang signifikan dan positif terhadap kunjungan pasien di Puskesmas Tepa. Adapun variabel yang paling berpengaruh terhadap kunjungan pasien di Puskesmas Tepa adalah variabel Responsiveness (Cepat Tanggap) dengan nilai signifikan sebesar 0,015 (p value < 0,05) OR = 0,025 (95% CI = 0,001 - 0,487) artinya responden yang merasa cepat tanggap (responsiveness) baik dari pelayan kesehatan mempunyai peluang 0,025 kali tidak puas terhadap responden yang menyatakan kurang cepat tanggap (responsiveness) dari petugas kesehatan dengan nilai koefisien B yaitu 3,691 bernilai positif, maka semakin kurang cepat tanggap (responsiveness) dari petugas kesehatan semakin kurang pasien yang melakukan kunjungan ke Puskesmas dengan pelayanan kesehatan gigi dan mulut di Puskesmas Tepa. Kesimpulan penelitian ini yaitu Tangible (Wujud), Reliability (Kehandalan), Responsiveness (Cepat Tanggap), Assurance (Kepastian) dan Emphaty (Empati) memiliki hubungan yang signifikan dan positif terhadap kunjungan pasien di Puskesmas Tepa. Kata Kunci: Wujud (Tangible); Kehandalan (Reliability); Cepat Tanggap (Responsiveness); (Assurance) Kepastian; Empati (Emphaty); Layanan Kesehatan Gigi dan Mulut Puskesmas Tepa Abstract Healthcare quality is an ongoing process that monitors service delivery and outcomes to assess the various patient visit frequency factors that influence healthcare services.. In this way, problems can be identified and their sources addressed, leading to better health and well-being for those who use health services.The purpose of this study was to analyze the relationship between the quality of dental and oral health services and patient visits to the Dental and Oral Polyclinic at the Tepa Health Center through the variables Tangible, Reliability, Responsiveness, Assurance and Empathy. Using a quantitative, cross-sectional approach.This research was conducted in the period of January-March 2025 which took place at the Tepa Health Center, West Babar Island District, Southwest Maluku Regency. The research sample was 76 respondents. The technique used is purposive sampling. Survey data were analyzed using the chi-square test and logistic regression. The results of this study indicate that Tangible, Reliability, Responsiveness, Assurance and Empathy have a significant and positive relationship with patient visits at the Tepa Health Center. The most influential variable on patient visits to the Tepa Health Center is the Responsiveness variable with a significant value of 0.015 (p value <0.05) OR = 0.025 (95% CI = 0.001 - 0.487) meaning that respondents who feel responsiveness from health services have a 0.025 times greater chance of being dissatisfied with respondents who state that the responsiveness of health workers is less than the responsiveness with a coefficient value of B, namely 3.691, which is positive, so the less responsiveness from health workers, the fewer patients will visit the Health Center with dental and oral health services at the Tepa Health Center. The conclusion of this study is that Tangible, Reliability, Responsiveness, Assurance and Empathy have a significant and positive relationship with patient visits at the Tepa Health Center. Keywords: Tangible; Reliability; Responsiveness; Assurance; Empathy; Tepa Community Health Center's dental and oral health services
Effectiveness of medium-chain triglyceride diet and low glycemic index therapy in drug-resistant childhood epilepsy: a systematic review, meta-analysis, and meta-regression Wiradarma, Elbert; Khosama, Herlyani; Warouw, Finny; Wariki, Windy M. V.; Jehosua, Seilly Yunita; Pertiwi, Junita Maja
Universa Medicina Vol. 44 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2025.v44.245-256

Abstract

Background Drug-resistant epilepsy (DRE) challenges clinical management, with many patients failing to find relief. Medium-chain triglyceride diet (MCTD) and low glycemic index therapy (LGIT) are emerging variants of the ketogenic diet. MCTD and LGIT show promise but lack clear efficacy data. The purpose of this systematic review was to evaluate and compare the efficacy of MCTD and LGIT in the management of pediatric patients with DRE. Methods Four databases were searched (PubMed, Embase, Scopus, and Cochrane Library) from November 2024 to February 2025. Two independent reviewers meticulously screened titles, abstracts, and full texts, ensuring adherence to predefined criteria.  Data extraction encompassed study characteristics, participant demographics, intervention details, and outcomes, including seizure frequency, percentage reduction, and adverse events. Statistical analyses were performed using R 4.2.2 software, assessing heterogeneity with Cochrane Q and I² and utilizing random-effects and common-effects models. Results From 1489 articles found, 487 duplicates were removed, 897 were excluded based on title and abstract screening, and of the 47 full-text articles assessed for eligibility, 31 articles were excluded, resulting in 16 articles (9 MCTD and 7 LGIT) included in this review. The pooled estimates for the proportion of children achieving seizure freedom, ≥90% seizure reduction, and ≥50% seizure reduction following the intervention were comparable between the MCTD and LGIT groups. Based on the random-effects model, the overall success proportion of MCTD in reducing seizure frequency was 0.20 [95 % Confidence Interval (CI), 0.14-0.27] (p<0.01). Meanwhile, in the LGIT group, the overall success proportion was 0.27 [95% CI,0.14- 0.45] (p<0.01). Conclusion Both MCTD and LGIT demonstrate comparable efficacy, and no definitive conclusion can be drawn regarding the superiority of one diet over the other.
ANALISIS FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PENERAPAN BUDAYA KESELAMATAN PASIEN DI RS GMIM SILOAM SONDER Kussoy, Kevin D W; Rampengan, Starry H.; Pertiwi, Junita Maja; Kaunang, Erling David; Kristanto, Erwin
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 2 (2025): AGUSTUS 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i2.48233

Abstract

Budaya keselamatan dalam industri kesehatan, dianggap sebagai inisiatif penting untuk meningkatkan keselamatan pasien dan rumah sakit merupakan salah satu sara pemberi layanan kesehatan. Tujuan penelitian ini yaitu untuk menganalisis faktor-faktor yang berhubungan dengan penerapan budaya keselamatan pasien di RS GMIM Siloam Sonder. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross sectional. Penelitian ini dilaksanakan di RS GMIM Siloam Sonder pada Mei-Juli 2025. Jumlah responden sebanyak 103 staf medis dan keperawatan. Instrument yang digunakan yaitu kuesioner. Data yang diperoleh dianalisis secara univariat, bivariat menggunakan uji fisher exact dan multivariat regresi logistic multinominal. Hasil uji fisher exact  diperoleh untuk kerjasama p=0,034, pengaturan staf dan tempo kerja p=0,827, pembelajaran organisasi p=0,724, respon terhadap eror p=0,003, dukungan supervisor p=0,016, komunikasi tentang eror p=0,094, keterbukaan komunikasi p=0,364, pelaporan kejadian p=0,325, dukungan manajemen p=0,025 dan penyerahan dan pertukaran informasi p=0,188. Hasil analisis multivariat ditemukan nilai -2 log likelihood of reduced model tertinggi yaitu dengan nilai 17,561 pada variabel respon terhadap eror dan nilai sig. 0,011. Kesimpulan penelitian ini yaitu faktor yang tidak berhubungan yaitu pengaturan staf dan tempo kerja, pembelajaran organisasi, komunikasi tentang eror, keterbukaan komunikasi, pelaporan kejadian serta penyerahan dan pertukaran informasi, sedangkan faktor yang berhubungan  dengan penerapan budaya keselamatan pasien di RS GMIM Siloam Sonder yaitu faktor kerjasama, respon terhadap eror, dukungan supervisor dan dukungan manajemen. Faktor yang paling berhubungan yaitu respon teradap eror.
Co-Authors Angelina Stevany Regina Masengi Budi Setiawan Daniel Febrian Sengkey Edward Nangoy, Edward Erling David Kaunang Erwin Kristanto Goni, Angelina Herlina I. S. Wungouw Herlyani Khosama Jehosua, Seilly Yunita Jimmy Posangi Kussoy, Kevin D W Lapian, Albertus Theo Mamahit, Juliet Merry Eva Mambo, Christi Diana Marthen Theogives Lasut, Marthen Theogives Mieke A.H.N. Kembuan, Mieke A.H.N. Momole, Ansye G.N. Momole, Ansye Grace Nancy Ngantung, Denny Pati, Josefa M. Rizal Tumewah Slarmanat, Intan Indah S. Starry H. Rampengan Tangkudung, Gilbert Tongku, Aurelia Sartika Tumboimbela, Melke Wariki, Windy M. V. Warouw, Finny William William Wiradarma, Elbert Wulan Pingkan Julia Kaunang Yulianty Sanggelorang