Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Jurnal Bios Logos eJournal Kedokteran Indonesia
Mambo, Christi Diana
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Skrining Fitokimia dan Uji Aktivitas Antibakteri Ekstrak Etanol Daun Binahong (Anredera cordifolia (Ten.) Steenis) Terhadap Streptococcus mutans dan Escherichia coli Achmad, Mardhita Nilamsari; Masengi, Angelina Stevany Regina; Posangi, Jimmy; Fatimawali; Mambo, Christi Diana
JURNAL BIOS LOGOS Vol. 14 No. 3 (2024): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v14i3.54394

Abstract

Tanaman binahong (Anredera cordifolia (Ten.) Steenis) telah dimanfaatkan sebagai bahan alami dalam pengobatan. Tanaman ini memiliki kandungan senyawa aktif seperti flavonoid yang dapat bertindak sebagai antibiotik dengan cara mengganggu fungsi mikroorganisme seperti bakteri. Penelitian ini bertujuan untuk menguji kandungan senyawa aktif dalam ekstrak etanol daun binahong terhadap zona hambat pertumbuhan bakteri Streptococcus mutans dan Escherichia coli. Jenis penelitian yang digunakan ialah eksperimental laboratorium. Hasil skrining fitokimia menunjukkan ekstrak etanol daun binahong mengandung senyawa aktif seperti flavonoid, tanin, alkaloid, polifenol, saponin, dan steroid. Hasil pengukuran zona hambat terhadap streptococcus mutans dengan metode cakram menggunakan konsentrasi 20%, 40%, dan 60% diperoleh nilai rata-rata sebesar 9,38 mm, 9,90 mm, dan 11,20 mm, sedangkan pada Escherichia coli diperoleh nilai rata-rata sebesar 8,53 mm, 9,12 mm, dan 10,23 mm. Hasil pengukuran zona hambat terhadap streptococcus mutans dengan metode sumuran menggunakan konsentrasi 20%, 40%, dan 60% diperoleh nilai rata-rata sebesar 10,35 mm, 11,28 mm, dan 12,85 mm, sedangkan pada Escherichia coli diperoleh nilai rata-rata sebesar 9,93 mm, 10,25 mm, 11,50 mm. Berdasarkan hasil tersebut dapat disimpulkan bahwa ekstrak etanol daun binahong memiliki potensi dalam menghambat pertumbuhan bakteri Streptococcus mutans dan Escherichia coli.
The Relationship Between Pesticide Use and Cognitive Impairment in an Agricultural Community of Tomohon City, North Sulawesi Masengi, Angelina Stevany Regina; Mambo, Christi Diana; Nangoy, Edward; Posangi, Jimmy; Lasut, Marthen Theogives; Pertiwi, Junita Maja; Warouw, Finny; Sanggelorang, Yulianty; Sengkey, Daniel Febrian; Mamahit, Juliet Merry Eva
eJournal Kedokteran Indonesia Vol. 13 No. 1 (2025): Vol 13, No. 1 - April 2025
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23886/ejki.13.961.42

Abstract

This study investigates the cognitive effects of pesticide exposure on agricultural workers from a village in Tomohon City, North Sulawesi, Indonesia. Employing a cross-sectional design from July to September 2024. This study assessed the demographic characteristics, pesticide exposure patterns, and cognitive function of 97 participants aged 18 using the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA-INA.The findings reveal a clear association between direct and indirect pesticide exposure and cognitive impairment. Direct exposure was linked to slightly lower cognitive scores than indirect exposure, with both groups scoring below established thresholds for normal cognitive function, particularly in memory, attention, and executive functions. Inconsistent use of personal protective equipment was noted among participants, with common immediate symptoms including visual disturbances and memory deficits following pesticide application. These results suggest that minimal pesticide exposure may contribute to cognitive decline, potentially accelerating age-related impairments. The underlying neurotoxic mechanisms likely involve oxidative stress, mitochondrial dysfunction, and neuroinflammation, which disrupt neuronal integrity. These findings underscore the urgent need for enhanced occupational health policies, stricter safety measures, and further research to mitigate the cognitive risks of pesticide exposure in agricultural populations.
Co-Authors Achmad, Mardhita Nilamsari Angelina Stevany Regina Masengi Daniel Febrian Sengkey Edward Nangoy, Edward Fatimawali . Jimmy Posangi Mamahit, Juliet Merry Eva Marthen Theogives Lasut, Marthen Theogives Pertiwi, Junita Maja Warouw, Finny Yulianty Sanggelorang