Article Per Year (5 Year)
p-Index From 2020 - 2025
1.879
P-Index
This Author published in this journals
All Journal JURNAL FARMASIMED (JFM) Jurnal Prima Medika Sains Jurnal Pengmas Kestra (JPK)
Cahya, Cucu Arum Dwi
Unknown Affiliation
Health Professions Medicine & Pharmacology Nursing Public Health

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 12 Documents
Search

 1   2 
Analysis of Rhodamin B Levels in Lipbalms Sold Online Using Uv-Vis Spectrophotometry Cahya, Cucu Arum Dwi; Saragih, Agustinus; Br Sinaga, Hana Lorenta
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2352

Abstract

A frequent cosmetic preparation for moisturizing and shielding dry lips is lip balm. The textile industry uses a synthetic dye called rhodamine B. Because rhodamine B is a synthetic dye having carcinogenic qualities that can encourage the formation of cancer cells if used repeatedly, the Indonesian Food and Drug Administration (BPOM) forbids its usage as a cosmetic colorant. The purpose of the study is to ascertain, both qualitatively and quantitatively, if five distinct lip balm brands sold online contain the dangerous synthetic pigment Rhodamine B. The study was conducted quantitatively using UV Vis spectophotometry and qualitatively using the Thin Layer Chromatography (TLC) test and color response test with the reagents used, 10% NaOH. One of the five samples (sample B) tested positive for Rhodamine B according to the color response and TLC tests. With an Rf value of 0.91, which is near the typical Rhodamine B Rf value of 0.96, this was demonstrated by a color shift to red-orange upon the addition of 10% NaOH. Visual inspection of Sample B revealed a pink area as well. Rhodamine B was not detected in samples A, C, D, or E.Sample B had an average Rhodamine B content of 3,2281 mg/g.
Isolation and Structural Elucidation of Flavonoid Compounds from Ciplukan (Physalis angulata L.) Leaf Extract Cahya, Cucu Arum Dwi; Sinurat, Jhon Patar; Br Turnip, Nur Ulina M.; Br Karo, Reh Malem
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2667

Abstract

The exploration and utilization of herbal medicines continue to expand due to the presence of plant-derived secondary metabolites, which have been proven to prevent and treat various diseases with minimal side effects. One plant widely recognized for its medicinal properties is Physalis angulata L. (commonly known as ciplukan). Despite its frequent use in traditional medicine, particularly its leaves, limited studies have focused on the isolation of flavonoid compounds from this part of the plant. The isolation and structural elucidation of these flavonoids are essential to identify the bioactive compounds responsible for the plant's pharmacological effects. This study aimed to isolate and elucidate the chemical structure of flavonoid compounds from P. angulata leaf extract. The powdered leaves were subjected to maceration, solvent partitioning, phytochemical screening, thin-layer chromatography (TLC), and compound isolation using column chromatography. The isolated compounds were then characterized using UV-Visible (UV-Vis) spectroscopy, Fourier-transform infrared spectroscopy (FT-IR), nuclear magnetic resonance (NMR), and mass spectrometry (MS). The flavonoid compound isolated in this study was identified as quercetin (C??H??O?), a member of the flavonol subclass. It exhibited a molecular mass of 302 g/mol and showed maximum absorbance at wavelengths of 372.5 nm and 305.5 nm. Spectroscopic analyses revealed the presence of functional groups including C–O, C=C, C=O, CH, and OH, as well as 10 hydrogen and 15 carbon atoms in the NMR spectra. Based on these data, the isolated compound was confirmed to be 3,3',4',5,7-pentahydroxyflavone, commonly known as quercetin, with the molecular formula C??H??O?.
Co-Authors Br Sihombing, Amelya Chyntia Br Sinaga, Hana Lorenta Br Sinaga, Irma Suryani Kristina Br Turnip, Nur Ulina M. Br. Turnip, Nur Ulina M. Harahap, Hasni Yaturramadhan Hasibuan, Ahmad Syukur Lubis, Devi Febby Yola Nur Ulina M. Br. Turnip Priasa, Ayunda Purba, Novandi Reh Malem br Karo Saragih, Agustinus Silalahi, Mega Sinurat, Jhon Patar Suci Wulandari Sunariati, Sunariati Syarifuddin, Aminah Syarifuddin, Shofian Syukur, Ahmad Syukur