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All Journal International Journal of Public Health Science (IJPHS) YARSI Medical Journal
Natsir, Rosdiana
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Health Professions Medicine & Pharmacology

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POPULASI BAKTERI PADA TANAH BEKAS BUANGAN LIMBAH MERKURI TAMBANG EMAS DI KABUPATEN BOLAANG MONGONDOW: PENELITIAN PENDAHULUAN Fatimawali, Fatimawali; Kepel, Billy; Yusuf, Irawan; Natsir, Rosdiana; Baharuddin, Fatmawaty
Jurnal Kedokteran YARSI Vol 17, No 2 (2009): MEI - AGUSTUS 2009
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.068 KB) | DOI: 10.33476/jky.v17i2.207

Abstract

Mercury is one of the most toxic heavy metals found in nature. Athough adverse health effect of mercury have been known for a long time, exposure to mercury continues and is even increasing in some areas, for example, mercury is still used in gold mining in many parts of North Sulawesi Province. Most of the soil and aquatic bacteria that are continuously exposed to mercury usually develop a genetic adaptation to resist the toxicity of this compound. Bacteria have a specific operon called merOperon that functions to coordinate genes coding for proteins and enzymes involved in mercury disposal and detoxification. Therefore, this preliminary study aims to isolate and identify bacteria collected from gold mining area in the district of Bolaang Mongondow. Bacteria were isolated from soil samples collected from three locations of the gold mining waste disposal and the isolated bacteria were grown in agar media. Identification of the grown bacteria were then be performed using morphological, physiological and biochemical tests. The results showed that 36 bacteria were successfully isolated, of which, 11 isolates were gram positive bacteria and the remainders were gram negative. All isolates showed motility and all could be grouped into 4 species i.e. Bacillus sp., Escherichia coli, Enterobacter cloacea, and Enterobacter aerogenes.
Correlation of offspring thyroid function and maternal iodine status in iodine deficient-coastal area Ekawanti, Ardiana; As’ad, Suryani; Natsir, Rosdiana; Umar, Husaini; Irawati, Deasy; Kadriyan, Hamsu; Zubaidi, Fitriannisa Faradina; Ayunda, Rahmah Dara
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.23794

Abstract

Thyroid hormone is vital for children's growth and metabolism, relying on sufficient iodine levels for synthesis. Maternal intake determines iodine supply to fetuses and children under two years old. This study aimed to correlate offspring thyroid function with maternal iodine status in coastal areas. A cohort study was conducted, involving pregnant coastal residents. Maternal urinary iodine levels were measured via the ammonium persulfate method, while offspring thyroid stimulating hormones (TSHs) and free thyroxine hormone (fT4) levels were assessed using electro-chemiluminescence immunoassay (ECLIA). Iodine intake was determined through a semiquantitative food frequency questionnaire (FFQ). The correlation between offspring thyroid function and maternal iodine status was analyzed using Pearson’s correlation test. Differences in TSHs and fT4 levels among iodine status groups were examined using the One way-ANOVA test. Maternal iodine status was insufficient with a median urinary iodine of 125 μg/L, resulting in a 60.8% prevalence of iodine insufficiency. Iodine intake (62.20±43.45 μg/day) fell short of recommended levels (RDA). Offspring TSH was 2.29±1.07 μIU/mL, fT4 was 1.26±0.14 ng/dL. TSH and fT4 concentrations showed no significant inter-group differences (p=0.852, p=0.075). Offspring thyroid function did not correlate with maternal iodine status (TSHs: p=0.314; fT4: p=0.258). Offspring thyroid function did not correlate to maternal iodine status in a population of iodine-insufficient and mercury-contaminated coastal areas.
Co-Authors Ardiana Ekawanti As’ad, Suryani Ayunda, Rahmah Dara Baharuddin, Fatmawaty Billy Kepel Deasy Irawati Fatimawali . Irawan Yusuf Kadriyan, Hamsu Umar, Husaini Zubaidi, Fitriannisa Faradina