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Corrigendum: Effects of 7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-chroman-4-one on serum levels of antioxidant enzymes in hyperlipidemic rats Prasetyastuti, .; Gama, Noviyanty Indjar; Ayunda, Rahmah Dara
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 55, No 3 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/MedSci005503202311

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Isolasi bakteri asam laktat asal feses bayi dan potensinya dalam menghambat pertumbuhan Escherichia coli Hasbi, Nurmi; Rosyunita; Rahim, Adelia Riezka; Ayunda, Rahmah Dara; Parwata, Wayan Sulaksmana Sandhi; Farras, Afif; Raihan, Al Fikar; Billah, Muhammad Azim
Jurnal Kedokteran Universitas Palangka Raya Vol 12 No 1 (2024): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v12i1.12852

Abstract

Lactic acid bacteria (LAB) play an important role in improving performance and mitigating disease because of their ability to maintain the physiological balance of the gastrointestinal tract and resistance to pathogenic bacteria. LAB is one of the bacteria found in the digestive tract. LAB must be isolated from their hosts to increase their efficiency as probiotic ingredients. This study aims to obtain local isolates of LAB a from baby feces through phenotypic identification and antibacterial test. The sample used in the research was the feces of babies aged 1-6 months that patients from Mataram University Hospital. Isolation was carried out by growing bacteria from feces using the Total Plate Count method on MRSA media plus CaCO3. Phenotypic characterization is morphology test, gram stain and biochemical tests. The results of bacterial isolation obtained 8 isolates of LAB. LAB produced a clear zone in the MRSA media, because these bacteria were able to secrete acid in the MRSA. The results of gram staining show that all isolates are gram positive bacteria. Based on the morphology of LAB had characteristic 6 isolates of cocci and 2 isolates of bacilli. All isolates was able to produce an inhibition zone against E. coli with 3 isolates in the moderate category and 5 isolates in the weak category. The best inhibition zone in the medium category is for cocci-shaped bacteria.The existence of LAB isolates from baby feces can be used as a reference source for further research on probiotics such as other antibacterial test
Correlation of offspring thyroid function and maternal iodine status in iodine deficient-coastal area Ekawanti, Ardiana; As’ad, Suryani; Natsir, Rosdiana; Umar, Husaini; Irawati, Deasy; Kadriyan, Hamsu; Zubaidi, Fitriannisa Faradina; Ayunda, Rahmah Dara
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.23794

Abstract

Thyroid hormone is vital for children's growth and metabolism, relying on sufficient iodine levels for synthesis. Maternal intake determines iodine supply to fetuses and children under two years old. This study aimed to correlate offspring thyroid function with maternal iodine status in coastal areas. A cohort study was conducted, involving pregnant coastal residents. Maternal urinary iodine levels were measured via the ammonium persulfate method, while offspring thyroid stimulating hormones (TSHs) and free thyroxine hormone (fT4) levels were assessed using electro-chemiluminescence immunoassay (ECLIA). Iodine intake was determined through a semiquantitative food frequency questionnaire (FFQ). The correlation between offspring thyroid function and maternal iodine status was analyzed using Pearson’s correlation test. Differences in TSHs and fT4 levels among iodine status groups were examined using the One way-ANOVA test. Maternal iodine status was insufficient with a median urinary iodine of 125 μg/L, resulting in a 60.8% prevalence of iodine insufficiency. Iodine intake (62.20±43.45 μg/day) fell short of recommended levels (RDA). Offspring TSH was 2.29±1.07 μIU/mL, fT4 was 1.26±0.14 ng/dL. TSH and fT4 concentrations showed no significant inter-group differences (p=0.852, p=0.075). Offspring thyroid function did not correlate with maternal iodine status (TSHs: p=0.314; fT4: p=0.258). Offspring thyroid function did not correlate to maternal iodine status in a population of iodine-insufficient and mercury-contaminated coastal areas.
CERDAS CERMAT TENTANG PENCEGAHAN PAJANAN MERKURI PADA SISWA SD DI DAERAH LINGKAR TAMBANG KABUPATEN LOMBOK BARAT Ekawanti, Ardiana; Irawati, Deasy; Nurbaiti, Lina; Zubaidi, Fitriannisa Faradina; Ayunda, Rahmah Dara; Abdurrosyid, Muhammad
Jurnal Pepadu Vol 5 No 3 (2024): Jurnal PEPADU
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v5i3.5849

Abstract

Provinsi Nusa Tenggara Barat memiliki beberapa lokasi pertambangan emas skala kecil, (PESK) baik di pulau Lombok maupun Sumbawa. PESK menjadi salah satu penyumbang emisi merkuri terbesar di dunia. Merkuri adalah bahan kimia yang digunakan dalam proses pengolahan emas. Manusia terpajan merkuri melalui kulit, saluran napas dan melalui saluran cerna. Pajanan merkuri ini memberikan dampak pada kesehatan. Penelitian Ekawanti dkk (2023), didapatkan kejadian peningkatan kadar merkuri di atas ambang WHO sebesar 70 % pada daerah pertambangan emas. Anak- anak yang tinggal di daerah PESK terdampak secara tidak langsung oleh merkuri, bahkan ada yang terdampak langsung karena terlibat dalam proses pengolahan emas membantu orang tuanya. Pengabdian ini bermaksud untuk memberikan pengetahuan bagi siswa SD tentang sumber pajanan merkuri dari lingkungan dan cara mencegah pajanan tersebut. Metode yang digunakan adalah permainan edukatif berupa cerdas cermat setelah diberikan booklet tentang pajanan merkuri dan dampaknya. Pengabdian ini dilaksanakan pada tanggal 6 Mei 2024 yang berlokasi di SDN 1 Buwun Mas. Cerdas cermat diikuti oleh 2 gugus tugas dengan jumlah 12 SD. Kegiatan didahului dengan kegiatan koordinasi Bersama dengan ketua gugus, dan kepala sekolah pada tanggal 29 April 2024 yang bertempat di SDN 1 Buwun Mas di daerah Sepi, pada rapat tersebut sekaligus diserahkan booklet kepada kepala sekolah, sebagai bahan untuk cerdas cermat. Acara cerdas cermat ini menghasilkan pemenang sebagai “duta merkuri”, yaitu SDN 1 Buwun Mas, SDN 2 Buwun Mas dan SDN 3 Buwun Mas. Kesimpulan kegiatan pengabdian ini adalah kegiatan cerdas cermat pencegahan pajanan merkuri sudah terlaksana dengan baik, dengan pemenang sebagai duta merkuri.
Isolasi Staphylococcus aureus dari Swab Tangan Penjamah Makanan di Kantin Universitas Mataram Hasbi, Nurmi; Rosyunita; Rahim, Adelia Riezka; Ayunda, Rahmah Dara
Jurnal Kedokteran Universitas Palangka Raya Vol 12 No 2 (2024): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v12i2.15313

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One of the main qualities of food is seen from the biological safety aspect, such as being free from Pathogenic microorganisms. Staphylococcus aureus is a pathogenic bacterium that can contaminate food ingredients come from the skin of food handlers. S. aureus produces enterotoxins that have a poisoning in consumers.The preliminary observationstated that there were still many food handlers in the Mataram University canteen who did not pay attention to hand hygiene and personal sanitation. This study aims to determine the bacterial contamination of S. aureus swabbed from the hands of food handlers in the Mataram University cafetaria. The method was used in this research is descriptive observational. The research consisted of two stages, namely isolation and biochemical identification. The isolation stage resulted 10 culturable bacterial isolates. All bacteria were able to ferment mannitol on Mannitol Salt Then, the biochemical test identification resulted that all isolates had a positive catalase test, a positive slide coagulase test, Gram-positive, and staphylococci cell. The TSIA test resulted A/A or (acid)/(acid) which indicated that all isolates were able to use diverse carbon sources from sucrose, lactose, glucose. Moreover, other test as sulfur, indole and motility tests were negative. Therefore, all isolates in this study are classified as S. aureus. This research is also a promotive and preventive effort for the campus in implementing hygiene and sanitation for food handlers in the cafetaria.
Mercury Induced Immunological Disorders Abdurrosyid, Muhammad; Ekawanti, Ardiana; Ayunda, Rahmah Dara
PROMOTOR Vol. 8 No. 3 (2025): JUNI
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v8i3.1218

Abstract

The immune response to mercury is unique, it can be immunosuppressive and immunomodulative. The immune response to mercury begins with exposure to mercury from the environment originating from natural activities such as volcanic activity and human activities such as gold processing from artisanal small scale gold mining and chlorine alkali factories, or from consumption mercury- contaminated fish. These mercury sources release inorganic and organic mercury which enters the human body through inhalation, ingestion and absorption through the skin. The entry of mercury into the body will induce innate and adaptive immune responses. The immune response to mercury is immunomodulative and triggers proinflammatory substances production. This mechanism is the pathological basis for clinical manifestations of mercury intoxication in the kidneys, central nervous system, respiratory tract and skin.
Penerapan Game Interaktif dalam Edukasi Perilaku Hidup Bersih dan Sehat (PHBS) sebagai Strategi Pencegahan Stunting di SDN 10 Ampenan Ayunda, Rahmah Dara; Wiwin Lastyana; Azizatul Adni; Lale Justin Amelinda Elizar
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 3 (2025): Juli-September 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i3.12502

Abstract

Stunting merupakan permasalahan gizi kronis yang berdampak pada pertumbuhan fisik dan perkembangan kognitif anak. Salah satu upaya pencegahan stunting adalah melalui edukasi gizi dan perilaku hidup bersih dan sehat (PHBS) sejak usia sekolah dasar. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan siswa SDN 10 Ampenan mengenai PHBS dan gizi seimbang melalui media edukatif Game Isi Piringku. Metode pelaksanaan meliputi tahap persiapan, penyuluhan interaktif, dan praktik permainan edukasi yang dirancang untuk memperkenalkan konsep gizi seimbang serta kebiasaan hidup bersih. Kegiatan diikuti oleh 20 siswa kelas V yang dibagi menjadi 5 kelompok kecil agar setiap siswa berkesempatan aktif bermain dan berdiskusi. Hasil kegiatan menunjukkan bahwa 3 kelompok mampu menyelesaikan permainan dengan benar, sedangkan 2 kelompok lainnya sudah memahami materi namun masih melakukan kesalahan kecil di beberapa bagian permainan. Kesimpulannya, Game Isi Piringku efektif sebagai media pembelajaran interaktif untuk mengenalkan PHBS dan gizi seimbang. Namun, diperlukan penguatan materi karena waktu antara penyampaian materi dan pelaksanaan permainan relatif singkat sehingga sebagian siswa belum mencapai pemahaman sempurna. Keywords: stunting, perilaku hidup bersih dan sehat, gizi seimbang, game edukasi, sekolah dasar
Relationship between Body Mass Index and Anemia in Adolescent Girls at Madrasah Aliyah Nurul Islam Arsy, Lazuardi; Cholidah, Rifana; Ayunda, Rahmah Dara
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7672

Abstract

Indonesia, 4 out of 10 teenagers suffer from anemia. Adolescent girls have a higher likelihood of experiencing anemia due to physical and psychological changes that affect greater nutritional needs. Some references associate anemia with differences in body mass index, thus further research is needed on the relationship between body mass index and the occurrence of anemia. This study aims to determine the relationship between Body Mass Index and the occurrence of Anemia in adolescent girls at MA Nurul Islam. The research design used in this study is cross-sectional. The population consisted of adolescent girls aged 15-18 years from MA Nurul Islam who had started menstruating. The study employed consecutive sampling technique, involving a total of 46 participants. The chi-square test results indicate no association between body mass index and the occurrence of anemia (p = 1.000; PR = 0.800; 95% CI = 0.178-3.587). Additionally, other characteristics such as menstrual duration, menstrual cycle, iron supplement consumption, and parental income also did not show significant associations with the occurrence of anemia among adolescent girls at MA Nurul Islam in this study. This study found no association between body mass index (BMI) and the incidence of anemia in adolescent girls at MA Nurul Islam. Other characteristics examined, such as menstrual duration, menstrual cycle, iron supplement consumption, and parental income, also did not show significant associations with the occurrence of anemia. Therefore, further research with different approaches is needed to evaluate other factors that may affect anemia in adolescent girls.
The Potential of Active Compounds in Traditional Herbal Plants from Lombok for Their Use in Dyslipidemia Christian, Steven; Abdiman, I Made Tobias; Amaliya, Annisa Risqi; Shofa, Dhiya Atsila; Balqis, Ananda Amirah; Sesariana, Mayumi Agestia; Ayunda, Rahmah Dara
Jurnal Biologi Tropis Vol. 24 No. 2b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2b.7788

Abstract

Dyslipidemia is a condition characterized by abnormal lipid levels in the blood, including total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides. This condition can lead to complications such as cardiovascular diseases and stroke. The purpose of this study is to explore the potential of herbal plants from the Sasak tribe, as recorded in Lontar Usada, for managing dyslipidemia. Lontar Usada documents various medicinal plants that are traditionally used by the Sasak people, making it essential to investigate their active compounds and how they influence lipid profiles. This research employs a qualitative approach, focusing on a literature review and analysis of the plants mentioned in Lontar Usada, followed by a biochemical evaluation of their active compounds and mechanisms in regulating lipid metabolism. The findings reveal that several plants listed in Lontar Usada contain bioactive compounds with potential lipid-lowering effects, supporting their traditional use in managing dyslipidemia. In conclusion, the study confirms that the plants from Lontar Usada could offer a natural alternative for dyslipidemia management, aligning with the high cultural acceptance and availability of these plants within the Sasak community.
Antibibiotics Susceptibility Testing Against Staphylococcus Aureus from Nasal Isolates in Food Handlers in Canteen of Mataram University Suryantarini, Ni Wayan Puspa Wijaya; Hasbi, Nurmi; Ayunda, Rahmah Dara
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7891

Abstract

Staphylococcal food poisoning is caused by bacteria Staphylococcus aureus that contaminate food such as through transmission from the nose of the food handlers. Severe bacterial food poisoning requires appropriate antibiotic therapy. This study aims to test the susceptibility and compare the diameter of the inhibition zones of several antibiotics against S. aureus. The study is an experimental analytical consisting of sterilization of materials and antibiotics sensitivity testing using disc diffusion technique with replication. Statistical tests were carried out using the SPSS One Way ANOVA and Post Hoc Test. The result showed that S. aureus was still sensitive to four antibiotics with the average diameter for gentamicin, ciprofloxacin, clindamycin, and chloramphenicol were 17.7 mm, 28.95 mm, 23.58 mm, and 23.08 mm, respectively. Statistical tests showed a significant difference in the diameter of inhibition zone from four antibiotics (p < .05). Ciprofloxacin produced the largest inhibition zone and gentamicin produced the smallest zone, while clindamycin and chloramphenicol did not show a significant difference (p > .05). It can be concluded that the four antibiotics are still suitable to treat diseases such as food poisoning caused by S. aureus. Personal hygiene of food handlers is important to prevent transmission of disease through food. Prevention of antibiotic resistance is carried out by paying attention to the appropriate use of antibiotics in the community. Further research with the larger size of sample and other antibiotics using different techniques is needed.