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All Journal ODONTO Dental Journal Jurnal Bakti Saraswati Interdental Jurnal Kedokteran Gigi (IJKG) Jurnal Aplikasi dan Inovasi Iptek (JASINTEK) Suluh Pendidikan: Jurnal Ilmu-ilmu Pendidikan LOKATARA SARASWATI Odonto dental journal
Ni Wayan Arni Sardi
Universitas Mahasaraswati Denpasar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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Antibacterial Activity of Bidara Arab Leaves (Ziziphus spina-christi L) Extract Against Gram-negative Anaerobic Subgingival Bacteria Syahriel, Dwis; Hervina, Hervina; Sardi, Ni Wayan Arni
Odonto : Dental Journal Vol 11, No 2 (2024): December 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.2.241-250

Abstract

Background: Gram-negative anaerobic subgingival bacteria play an important role in the initiation and progression of periodontitis. The secondary metabolites contained in Bidara Arab leaves (Ziziphus spina-christi L) have potential to be antibacterial and inhibited the growth of pathogenic bacterial. The purposed of this study to evaluated the antibacterial activity of Bidara Leaves extract against gram-negative anaerobic subgingival bacteria. Method: Experimental laboratories using Mueller hinton agar to determine the antibacterial activity of Bidara leaves extract 40% and 60% against Porphyromonas gingivalis, Aggregatibacter ctinomycetemcomitans, and Fusobacterium nucleatum, with a comparison of the negative control group ethanol 96% and tetracycline as positive control. The production of extracts through maseration techniques and the subsequent phytochemical testing through tube reaction test. Result: The results of phytochemical analysis identified the presence of flavonoids, tannins, saponins, steroids. The inhibition test showed that the Bidara leaves extract exhibited strong inhibition and a concentration of  60% was more effective than 40% against Gram-negative anaerobic subgingival bacteria including Porphyromonas gingivalis, Aggregatibacter ctinomycetemcomitans, and Fusobacterium nucleatum. Conclusion: The Bidara Arab leaves (Ziziphus spina-christi L) extract at concentration 60% was more effective than 40% against gram-negative anaerobic bacteria
EDUKASI MASYARAKAT MELALUI PAMFLET SEBAGAI UPAYA PENCEGAHAN GIGI BERLUBANG DAN PENYAKIT MULUT Kadek Dwi Dessy Sapitri; Hendri Poernomo; Ni Wayan Arni Sardi
LOKATARA SARASWATI Vol 4 No 2 (2025): Lokatara Saraswati: Jurnal Pengabdian kepada Masayarakat
Publisher : Fakultas Bahasa Asing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/lokasaraswati.v4i2.12847

Abstract

Besakih Village, located in Rendang District, Karangasem Regency, Bali, is a culturally rich village known for Besakih Temple, the largest and holiest temple in Bali, which also serves as a major tourist attraction. However, observations reveal that the community still lacks adequate oral health awareness. The level of knowledge about dental diseases such as cavities and periodontal disease remains low, increasing the risk of oral health problems. To address this issue, a Social Service program was held in 2025 focusing on oral health care in Besakih Village. This program provided free dental treatments including scaling, cavity fillings, and tooth extractions. In addition to treatment, oral health education was conducted, covering dental anatomy, cavity care, and prevention of periodontal disease. Informational pamphlets on oral hygiene maintenance were distributed to the community. The program targeted children and the general population to improve knowledge and awareness of oral health maintenance. It is expected that through this Social Service activity, the oral health quality of Besakih Village residents will significantly improve.
Increase in Interleukin-6 Levels in the Gingiva of Male Wistar Rats Induced by Porphyromonas gingivalis Sardi, Ni Wayan Arni; Yasa, Wayan Putu Sutirta; Linawati, Ni Made
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 3 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i3.12869

Abstract

Introduction: Interleukin-6 (IL-6) in healthy gingiva contributes to regulating the immune response and tissue homeostasis. Exposure of lipopolysaccharide (LPS) from the Porphyromonas gingivalis bacteria (P. gingivalis) in periodontal tissues can influence the role of IL-6, shifting it from a tissue homeostatic agent to a pro-inflammatory cytokine. This study aimed to determine the levels of IL-6 in the gingiva of male Wistar rats induced by P. gingivalis bacteria. Material and Methods: This research uses a posttest-only control group design. Thirty-two male Wistar rats were divided into two groups, each consisting of sixteen rats. The control group consisted of 16 male Wistar rats that were not induced with bacteria. The experimental group consisted of sixteen male Wistar rats with the induction of P. gingivalis bacteria. Results and Discussions: The results showed that the IL-6 levels in the healthy male Wistar rat group were lower than the IL-6 levels in the male Wistar rat group induced with P. gingivalis bacteria. More exposure to LPS due to the induction of P. gingivalis bacteria causes increased permeability of the gingival mucosal barrier, which can shift the tissue balance towards a pro-inflammatory state, resulting in increased production of IL-6. Conclusion: IL-6 levels increased in the gingiva of male Wistar rats induced with P. gingivalis bacteria.
Co-Authors Bagus Komang Satriyasa Dewa Ayu Puspawati Dian Tariningsih Dian Tariningsih Dwis Syahriel Hendri Poernomo Hervina Hervina Hervina I Dewa Made Sukrama I Wayan Wesna Astara Kadek Dwi Dessy Sapitri Luh Kadek Budi Martini Made Talitha Suryaningsih Pinatih Ni Luh Putu Sri Maryuni Adnyasari Ni Made Linawati Ni Putu Ratih Berliana Ekasari Ni Wayan Ekayanti YASA, WAYAN PUTU SUTIRTA