Article Per Year (5 Year)
p-Index From 2021 - 2026
1.116
P-Index
This Author published in this journals
All Journal Jurnal Farmasi Sains dan Komunitas Jurnal Mandala Pharmacon Indonesia Jurnal Riset Kefarmasian Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Sains dan Kesehatan
Arifin, Arfiani
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 6 Documents
Search

 1 
FORMULASI DAN EVALUASI KESTABILAN FISIK SEDIAAN MASKER GEL PEEL-OFF DARI SARI BUAH LEMON CUI (Citrus microcarpa Bunge.) Arifin, Arfiani; Suwitno, Nurmadani; Sartini, Sartini
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1349

Abstract

Lemon cui also known as fish lemon or kalamansi lemon is known to contain one of them vitamin C which has the potential as an antioxidant so that it can be applied as active ingredient in peel off mask preparations. The aims of this study weretoobtaining the best PVA concentration in the manufacture of peel-off gel masks from lemon cui juice that meet the stability test requirements. physique. The method of making a sample of lemon cui juice is obtained by grinding it using a blender, adding 100 mL of water and then separating the pulp to obtain the juice. The formulation of peel-off gel mask preparations uses variations in the concentration of PVA (Polyvinyl Alcohol), namely F1 (10%), F2 (13%) and F3 (16%). Physical stability tests included organoleptic tests, homogeneity tests, spreadability tests, pH tests, adhesion tests and drying time tests.The results showed that the preparations F1, F2 and F3  showed physical stability  based on the results of organoleptic tests, homogeneity tests, spreadability tests, pH tests, adhesion tests and drying time tests before and after accelerated storage conditions. Based on the test results obtained, it can be concluded that the formulation of the Lemon Cui peel-off gel mask preparation from the three concentrations of PVA met the requirements for physical stability. The best PVA concentration is 10% because it has the best dry time.
Antibacterial Activity Test of Noni Leaves (Morinda citrifolia L.) Ethanol Extract Ointment Against Staphylococcus aureus Bacteria Arifin, Arfiani; Djide, Natsir; Muhtar, Mardiyana
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005763

Abstract

Noni leaves (MorindacitrifoliaL.) are known to provide antibacterial properties and can be used in ointment formulations to prevent or eliminate germs that might cause infections, such as Staphylococcus aureus. This research aimedto formulate an ointment containing noni leaf ethanol extract that fulfills the physical quality test standards and to determine the antibacterial activity of various concentrations of ethanol extract of noni leaves in ointment preparations against Staphylococcus aureus bacteria. The extraction technique employed was maceration with 96% ethanol. The extracted substance was formulated into ointments with concentrations of 2.5%, 5%, and 10%. The antibacterial activity of the ointment was evaluated using the agar diffusion method with wells. Organoleptic, homogeneity, pH, spreadability, and adhesion tests demonstrated that the ointment at the three concentrations of 2.5%, 5%, and 10% satisfied the physical quality test standards. The antibacterial activity test revealed that a 96% ethanol extract of noni leaves inhibited the growth of Staphylococcus aureus bacteria with the maximum diameter of the inhibition zone at a concentration of 10% (15.26 mm) and was classified as strong. 
Formulasi Masker Gel Peel-Off Ekstrak Etanol Daun Petai Cina (Leucaena leucocephala (Lam.) De Wit.) sebagai Antijerawat terhadap Pertumbuhan Bakteri Propionibacterium acnes: Formulation of Peel-Off Mask Gel with Ethanol Extract of Chinese Petai Leaves (Leucaena leucocephala (Lam.) De Wit.) as an Anti-acne Against the Growth of Propionibacterium acnes Bacteria Arifin, Arfiani; Djide, Natsir; Nurhidayah, Nurhidayah
Jurnal Sains dan Kesehatan Vol. 6 No. 1 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i1.2075

Abstract

Propionibacterium acnes is one of the gram-positive bacteria that can lead to the development of acne. One of the plants with the potential to be an anti-acne agent is the Petai Cina leaf (Leucaena leucocephala (Lam.) De Wit.). This study aims to formulate a peel-off gel mask preparation of the ethanol extract of Petai Cina leaf (Leucaena leucocephala (Lam.) De Wit.) that meets the physical quality test requirements and to determine the antiacne activity of the formulation. The extraction method used was maceration with 96% ethanol solvent. From the obtained extract, peel-off gel mask preparations were made and tested for their minimum inhibitory concentration (MIC): FI (2.5%), FII (5%), and FIII (10%), Medi-klin® (positive control), and gel base (negative control). The antibacterial activity was tested using the well diffusion method. The results of this study showed that the peel-off gel mask preparations FI (2.5%), FII (5%), FIII (10%), and the gel base (negative control) met the physical quality test requirements. The results of the anti-acne activity testing against the growth of Propionibacterium acnes bacteria obtained concentrations of extract FI (2.5%) 18.53 mm, FII (5%) 18.85 mm, FIII (10%) 22.27 mm, Medi-klin® 26.43 mm, and the negative control of Petai Cina leaf 6 mm. This indicates that the ethanol extract of Petai Cinaleaf has inhibitory effects on the growth of Propionibacterium acnes bacteria as an anti-acne agent. Keywords:          Chinese petai leaves (Leucaena leucocephala (Lam.) De Wit.), Peel-off gel mask, Propionibacterium acnes, Anti-acne   Abstrak Propionibacterium acnes merupakan salah satu bakteri gram positif yang dapat mengakibatkan timbulnya jerawat. Salah satu tanaman yang berpotensi sebagai antijerawat adalah daun petai cina (Leucaena leucocephala (Lam.) De Wit.). Penelitian ini bertujuan untuk memformulasi sediaan masker gel peel-off ekstrak etanol daun petai cina (Leucaena leucocephala (Lam.) De Wit.) yang memenuhi syarat uji mutu fisik dan untuk mengetahui aktivitas antijerawat formulasi sediaan masker gel peel-off ekstrak etanol daun petai cina (Leucaena leucocephala (Lam.) De Wit.). Metode ekstraksi digunakan yaitu metode maserasi dengan pelarut etanol 96%. Ekstrak yang diperoleh dibuat sediaan masker gel peel-off yang telah di uji konsentrasi hambat minimumnya (KHM) dengan konsentrasi ekstrak FI (2,5%), FII (5%) dan FIII (10%), Medi-klin® (kontrol positif) dan basis gel (kontrol negatif). Pengujian aktivitas antibakteri menggunakan metode sumuran. Hasil penelitian sediaan masker gel peel-off FI (2,5%), FII (5%), FIII (10%) dan basis gel (kontrol negatif) memenuhi syarat uji mutu fisik. Hasil pengujian aktivitas antijerawat terhadap pertumbuhan bakteri Propionibacterium acnes diperoleh konsentrasi ekstrak FI (2,5%) 18,53 mm, FII (5%) 18,85 mm, FIII (10%) 22,27 mm, Medi-klin® 26,43 mm dan kontrol negatif daun petai cina 6 mm. Hal ini menunjukkan bahwa ekstrak etanol daun petai cina memiliki daya hambat terhadap pertumbuhan bakteri Propionibacterium acnes sebagai antijerawat. Kata Kunci:         Daun petai cina (Leucaena leucocephala (Lam.) De Wit.), Masker gel peel-off, Propionibacterium acnes, Antijerawat
Formulasi Clay Mask Ekstrak Etanol Daun Kecombrang (Etlingera elatior) serta Potensinya sebagai Antibakteri dan Antioksidan Arifin, Arfiani; Iqbal, Muhammad; Amri, Ayu Wandira A Baso
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.1017

Abstract

Kecombrang (Etlingera elatior) merupakan tanaman yang memiliki banyak manfaat terutama pada daunnya mengandung senyawa flavonoid yang mampu bertindak sebagai antibakteri dan sebagai antioksidan. Tujuan penelitian ini adalah untuk mengetahui konsentrasi ekstrak etanol daun kecombrang yang memenuhi syarat mutu fisik, untuk mengetahui efek iritasi dari sediaan clay mask pada kulit serta untuk mengetahui potensi antibakteri dan antioksidan pada sediaan clay mask ekstrak etanol daun kecombrang. Penelitian ini diawali dengan ekstraksi menggunakan metode maserasi dengan pelarut etanol 96%. Ekstrak yang didapatkan dibuat dalam sediaan clay mask yang sebelumnya dilakukan uji Konsentrasi Hambat Minimum (KHM) menggunakan metode dilusi cair dan diperoleh konsentrasi FI (1,5%), FII (2,5%), FIII (5%). Pengujian iritasi menggunakan metode patch test dan pengujian aktivitas antibakteri menggunakan metode difusi sumuran serta pengujian aktivitas antioksidan menggunakan metode DPPH. Hasil penelitian yang diperoleh sediaan clay mask ekstrak etanol daun kecombrang memenuhi syarat mutu fisik, tidak terdapat iritasi, dan hasil pengujian aktivitas antibakteri terhadap Cutibacterium acnes diperoleh diameter zona hambat FI (12,89 ± 1,10), FII (14,28 ± 0,89), dan FIII (16,06 ± 0,89) dengan kategori kuat serta hasil pengujian aktivitas antioksidan diperoleh nilai IC50 sediaan clay mask ekstrak etanol daun kecombrang FI (93,184 ± 0,11), FII (90,798 ± 0,11), dan FIII (87,209 ± 0,04) dengan kategori kuat. Hasil analisis statistik pengujian aktivitas antibakteri menggunakan Analisis Varians (ANAVA) menunjukkan ketiga formula berbeda secara signifikan (nilai sig. < 0,05) dan hasil analisis statistik pengujian aktivitas antioksidan menunjukkan bahwa ketiga formula tidak terdapat perbedaan nyata antar perlakuan terhadap aktivitas antioksidan karena nilai sig. > 0.05.
FORMULASI DAN UJI IRITASI SEDIAAN LULUR KRIM CANGKANG SOTONG (Sepia sp.) TERHADAP KELINCI (Oryctolagus cuniculus) Arifin, Arfiani; Ida, Nur; Rosmiyanti, Rosmiyanti
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.359

Abstract

Cuttlefish shell (Sepia sp.) contains calcium carbonate which has benefits in removing dead skin cells, regulating skin pigmentation, shrinking pores, removing acne and black spots and making skin brighter. The aims of this study were to formalize dosage form of cuttlefish shell cream scrub (Sepia sp.) that meets the physical quality requirements and to determine the potential irritation of cuttlefish shell (Sepia sp.) cream scrubs in rabbits (Oryctolagus cuniculus). Reseacrh methods include the dosage form of cuttlefish shell powder using sieve mesh 44, cream scrub formulations with variations in cuttlefish shell powder concentrations by 15%, 20% and 25%. Physical quality test carried iut includes organoleptic tests, homogeneity tests, scatter power tests and sticking power tests. The cream scrub formula irritation test was carried out by patch test method in rabbit test animals. The results of the study obtained that cuttlefish shell cream scrubs have qualified physical quality tests and the degree of irritation value of F1 cream scrubs (cuttlefish shell 15%) of 0,2 which is categorized means very mild irritation.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN KATANG (Ipomoea pes-caprae L.) ASAL WOLU PROVINSI MALUKU MENGGUNAKAN METODE DPPH Hasan, Tahirah; Irfayanti, Nur Alfiah; Arifin, Arfiani; Muhammad, Andila Sari
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.413

Abstract

Ipomoea pes-caprae (L.) is a plant that comes from the convolvulaceae family and is known to have benefits as antioxidant. This study aims to determine the antioxidant activity of ethanol extract of Maluku's katang leaf (Ipomoea pes-caprae L) against DPPH free radicals. Katang leaves simplicia was extracted using 70% ethanol by maceration Testing of antioxidant activity against DPPH free radicals was analyzed using a viable spectrophotometer at a wavelength of 515 nm. The results of the analysis showed that the antioxidant activity of ethanol extract of katang leaves (Ipomoea pes-caprae L.) had an IC50 value of 92.5266±1.83 pg/mL The antioxidant activity ability of katang leaf extract is 0.066 times compared to ascorbic acid with an IC50 value of 6.12810.07 μg/mL
Co-Authors Baso Amri, ayu wandira A Hasan, Tahirah Irfayanti, Nur Alfiah Muhammad Iqbal Muhammad, Andila Sari Muhtar, Mardiyana Natsir Djide Nur Ida Nurhidayah Nurhidayah Rosmiyanti, Rosmiyanti Sartini Sartini Suwitno, Nurmadani